Flt3lg (Fms related receptor tyrosine kinase 3 ligand) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Flt3lg (Fms related receptor tyrosine kinase 3 ligand) Rattus norvegicus
Analyze
Symbol: Flt3lg
Name: Fms related receptor tyrosine kinase 3 ligand
RGD ID: 2322792
Description: Used to study pancreatic cancer. Human ortholog(s) of this gene implicated in colon carcinoma; glioblastoma; high grade glioma; and immunodeficiency 125. Orthologous to human FLT3LG (fms related receptor tyrosine kinase 3 ligand); INTERACTS WITH bisphenol A; (+)-catechin (ortholog); 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AC099450.1; fms-related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand-like; Gm45713; LOC100363556; LOC102547607; LOC103691111; predicted gene 45713; rCG54594-like; uncharacterized LOC103691111
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,751,518 - 104,756,925 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1104,749,983 - 104,757,038 (-)EnsemblGRCr8
mRatBN7.2195,615,056 - 95,620,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,609,370 - 95,620,463 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1101,000,447 - 101,005,854 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,473,114 - 109,478,521 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,763,521 - 102,768,928 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,126,006 - 101,131,413 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,124,479 - 101,131,413 (-)Ensemblrn6Rnor6.0
Rnor_5.01102,190,086 - 102,197,519 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4195,607,131 - 95,611,290 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera189,873,472 - 89,878,870 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Inflammatory and anti-glioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression. Ali S, etal., Mol Ther. 2004 Dec;10(6):1071-84.
2. FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis. Desterke C, etal., Cancer Res. 2011 Apr 15;71(8):2901-15. doi: 10.1158/0008-5472.CAN-10-1731. Epub 2011 Apr 12.
3. Flt3 ligand lessens the growth of tumors obtained after colon cancer cell injection in rats but does not restore tumor-suppressed dendritic cell function. Favre-Felix N, etal., Int J Cancer. 2000 Jun 15;86(6):827-34.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model. King GD, etal., Neuro Oncol. 2008 Feb;10(1):19-31. Epub 2007 Dec 13.
6. Potential role of FLT3-ligand in the angiogenic process of multiple myeloma. Kokonozaki M, etal., Leuk Res. 2015 Dec;39(12):1467-72. doi: 10.1016/j.leukres.2015.10.009. Epub 2015 Oct 20.
7. Plasma/serum levels of flt3 ligand are low in normal individuals and highly elevated in patients with Fanconi anemia and acquired aplastic anemia. Lyman SD, etal., Blood. 1995 Dec 1;86(11):4091-6.
8. FLT3 activation improves post-myocardial infarction remodeling involving a cytoprotective effect on cardiomyocytes. Pfister O, etal., J Am Coll Cardiol. 2014 Mar 18;63(10):1011-9. doi: 10.1016/j.jacc.2013.08.1647. Epub 2013 Oct 30.
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Effect of Flt3 ligand gene transfer in experimental pancreatic cancer. Ryschich E, etal., Int J Colorectal Dis. 2007 Feb;22(2):215-23. Epub 2006 Mar 10.
11. Endogenous FLT-3 ligand serum levels are associated with disease stage in patients with myelodysplastic syndromes. Zwierzina H, etal., Leukemia. 1999 Apr;13(4):553-7.
Additional References at PubMed
PMID:7505204   PMID:7531700   PMID:7630197   PMID:8180375   PMID:8896402   PMID:12387740   PMID:14607906   PMID:20360400   PMID:21048959   PMID:21149635   PMID:23844157   PMID:23913046  


Genomics

Comparative Map Data
Flt3lg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,751,518 - 104,756,925 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1104,749,983 - 104,757,038 (-)EnsemblGRCr8
mRatBN7.2195,615,056 - 95,620,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,609,370 - 95,620,463 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1101,000,447 - 101,005,854 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,473,114 - 109,478,521 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,763,521 - 102,768,928 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,126,006 - 101,131,413 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,124,479 - 101,131,413 (-)Ensemblrn6Rnor6.0
Rnor_5.01102,190,086 - 102,197,519 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4195,607,131 - 95,611,290 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera189,873,472 - 89,878,870 (-)NCBICelera
Cytogenetic Map1q22NCBI
FLT3LG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,474,215 - 49,486,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,474,150 - 49,486,233 (+)Ensemblhg38GRCh38
GRCh371949,977,472 - 49,989,488 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,669,298 - 54,681,300 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341954,669,297 - 54,681,299NCBI
Celera1946,846,847 - 46,858,811 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,355,067 - 46,367,027 (+)NCBIHuRef
CHM1_11949,978,739 - 49,990,762 (+)NCBICHM1_1
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBIT2T-CHM13v2.0
Flt3l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,780,607 - 44,785,914 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,779,212 - 44,785,856 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38745,131,183 - 45,136,490 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,129,788 - 45,136,432 (-)Ensemblmm10GRCm38
MGSCv37752,386,559 - 52,391,802 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36744,999,456 - 45,004,327 (-)NCBIMGSCv36mm8
Celera740,584,281 - 40,589,522 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.14NCBI
Flt3lg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,365,938 - 1,370,002 (-)Ensembl
ChiLan1.0NW_0049555591,364,056 - 1,371,245 (-)NCBIChiLan1.0ChiLan1.0
FLT3LG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,589,080 - 55,601,931 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,509,418 - 57,522,277 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,486,169 - 46,499,008 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,410,448 - 55,422,545 (+)NCBIPanPan1.1PanPan1.1panPan2
FLT3LG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,015,222 - 107,025,181 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,015,223 - 107,024,708 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1106,598,496 - 106,607,982 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01107,535,285 - 107,544,772 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,535,286 - 107,545,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,208,335 - 107,217,819 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,850,390 - 106,859,883 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,691,506 - 107,700,992 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Flt3lg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,723,863 - 21,733,400 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,343,491 - 3,350,176 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,343,541 - 3,351,590 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLT3LG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,653,820 - 42,665,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,654,412 - 42,660,458 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607322,583,397 - 22,594,517 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flt3lg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248324,733,820 - 4,739,214 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Flt3lg
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12154,407,305 - 154,414,305 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Flt3lg
37 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1101228864146228864Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1102359314153680016Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1101594089146594089Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1100345976145345976Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat

Markers in Region
Flt3l  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,619,112 - 95,619,716 (+)MAPPERmRatBN7.2
Rnor_6.01101,130,063 - 101,130,666NCBIRnor6.0
Rnor_5.01102,195,571 - 102,196,174UniSTSRnor5.0
RGSC_v3.4195,610,167 - 95,610,770UniSTSRGSC3.4


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 92 59 6 356 192 11 138 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000027976   ⟹   ENSRNOP00000027976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,609,370 - 95,612,459 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082283   ⟹   ENSRNOP00000073852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1104,752,430 - 104,756,705 (-)Ensembl
mRatBN7.2 Ensembl195,615,057 - 95,620,243 (-)Ensembl
Rnor_6.0 Ensembl1101,126,969 - 101,131,012 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093210   ⟹   ENSRNOP00000076088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1104,752,430 - 104,756,705 (-)Ensembl
mRatBN7.2 Ensembl195,609,761 - 95,620,243 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,613,528 - 95,620,320 (-)Ensembl
Rnor_6.0 Ensembl1101,124,627 - 101,131,379 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093498   ⟹   ENSRNOP00000076117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1104,749,983 - 104,756,558 (-)Ensembl
mRatBN7.2 Ensembl195,613,525 - 95,620,463 (-)Ensembl
Rnor_6.0 Ensembl1101,124,479 - 101,131,050 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093559   ⟹   ENSRNOP00000076314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,609,761 - 95,620,243 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1101,129,300 - 101,129,720 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093729   ⟹   ENSRNOP00000076296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1104,752,430 - 104,757,038 (-)Ensembl
mRatBN7.2 Ensembl195,615,057 - 95,620,463 (-)Ensembl
Rnor_6.0 Ensembl1101,126,006 - 101,131,413 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000123250   ⟹   ENSRNOP00000106161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1104,750,731 - 104,756,558 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000136007   ⟹   ENSRNOP00000101209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1104,750,731 - 104,756,852 (-)Ensembl
RefSeq Acc Id: NM_001305939   ⟹   NP_001292868
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,751,518 - 104,756,925 (-)NCBI
mRatBN7.2195,615,056 - 95,620,463 (-)NCBI
Rnor_6.01101,126,006 - 101,131,413 (-)NCBI
Celera189,873,472 - 89,878,870 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001292868 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073852.2
  ENSRNOP00000076088.3
  ENSRNOP00000076117.3
  ENSRNOP00000076296
  ENSRNOP00000076296.3
  ENSRNOP00000101209.1
  ENSRNOP00000106161.1
RefSeq Acc Id: NP_001292868   ⟸   NM_001305939
- Peptide Label: precursor
- UniProtKB: A6JAY1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073852   ⟸   ENSRNOT00000082283
Ensembl Acc Id: ENSRNOP00000076296   ⟸   ENSRNOT00000093729
Ensembl Acc Id: ENSRNOP00000076117   ⟸   ENSRNOT00000093498
Ensembl Acc Id: ENSRNOP00000076088   ⟸   ENSRNOT00000093210
Ensembl Acc Id: ENSRNOP00000076314   ⟸   ENSRNOT00000093559
Ensembl Acc Id: ENSRNOP00000027976   ⟸   ENSRNOT00000027976
Ensembl Acc Id: ENSRNOP00000106161   ⟸   ENSRNOT00000123250
Ensembl Acc Id: ENSRNOP00000101209   ⟸   ENSRNOT00000136007

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2322792 AgrOrtholog
BioCyc Gene G2FUF-59710 BioCyc
Ensembl Genes ENSRNOG00000020618 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000056212 Ensembl
Ensembl Transcript ENSRNOT00000082283.3 UniProtKB/TrEMBL
  ENSRNOT00000093210.3 UniProtKB/TrEMBL
  ENSRNOT00000093498.3 UniProtKB/TrEMBL
  ENSRNOT00000093729 ENTREZGENE
  ENSRNOT00000093729.3 UniProtKB/TrEMBL
  ENSRNOT00000123250.1 UniProtKB/TrEMBL
  ENSRNOT00000136007.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/TrEMBL
  3.90.1180.10 UniProtKB/TrEMBL
  6.10.250.3250 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  Flt3_lig UniProtKB/TrEMBL
  Ribosomal_L13_sf UniProtKB/TrEMBL
NCBI Gene Flt3lg ENTREZGENE
PANTHER FMS-RELATED TYROSINE KINASE 3 LIGAND UniProtKB/TrEMBL
  PTHR11032 UniProtKB/TrEMBL
Pfam Flt3_lig UniProtKB/TrEMBL
PhenoGen Flt3lg PhenoGen
RatGTEx ENSRNOG00000020618 RatGTEx
  ENSRNOG00000056212 RatGTEx
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A0G2K6K8_RAT UniProtKB/TrEMBL
  A0A1W2Q602_RAT UniProtKB/TrEMBL
  A0A1W2Q636_RAT UniProtKB/TrEMBL
  A0A1W2Q6J3_RAT UniProtKB/TrEMBL
  A0ABK0L8I2_RAT UniProtKB/TrEMBL
  A0ABK0LV54_RAT UniProtKB/TrEMBL
  A6JAY1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Flt3lg  Fms related receptor tyrosine kinase 3 ligand  AC099450.1    Data merged from RGD:15003495 737654 PROVISIONAL
2021-02-23 AC099450.1    Gm45713  predicted gene 45713  Symbol and/or name change 19259462 PROVISIONAL
2020-12-03 Gm45713  predicted gene 45713  AC099450.1    Symbol and/or name change 19259462 PROVISIONAL
2020-01-03 Flt3lg  Fms related receptor tyrosine kinase 3 ligand  Flt3lg  fms-related tyrosine kinase 3 ligand  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-11-08 AC099450.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2015-04-10 Flt3lg  fms-related tyrosine kinase 3 ligand  LOC102547607  fms-related tyrosine kinase 3 ligand-like  Data merged from RGD:7750778 737654 APPROVED
2014-08-25 LOC103691111  uncharacterized LOC103691111      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-12-18 LOC102547607  fms-related tyrosine kinase 3 ligand-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-09-11 Flt3lg  fms-related tyrosine kinase 3 ligand  LOC100363556  rCG54594-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100363556  rCG54594-like      Symbol and Name status set to provisional 70820 PROVISIONAL