FLT3LG (fms related receptor tyrosine kinase 3 ligand) - Rat Genome Database

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Gene: FLT3LG (fms related receptor tyrosine kinase 3 ligand) Homo sapiens
Analyze
Symbol: FLT3LG
Name: fms related receptor tyrosine kinase 3 ligand
RGD ID: 1353824
HGNC Page HGNC:3766
Description: Predicted to enable identical protein binding activity and receptor tyrosine kinase binding activity. Involved in embryonic hemopoiesis and positive regulation of cell population proliferation. Predicted to be located in external side of plasma membrane. Predicted to be active in cell surface and extracellular space. Implicated in colon carcinoma; glioblastoma; and high grade glioma. Biomarker of Fanconi anemia; aplastic anemia; multiple myeloma; and myelofibrosis.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FL; FLG3L; flt3 ligand; FLT3L; fms related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; SL cytokine
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,474,215 - 49,486,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,474,207 - 49,486,231 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,977,472 - 49,989,488 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,669,298 - 54,681,300 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,669,297 - 54,681,299NCBI
Celera1946,846,847 - 46,858,811 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,355,067 - 46,367,027 (+)NCBIHuRef
CHM1_11949,978,739 - 49,990,762 (+)NCBICHM1_1
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Inflammatory and anti-glioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression. Ali S, etal., Mol Ther. 2004 Dec;10(6):1071-84.
2. FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis. Desterke C, etal., Cancer Res. 2011 Apr 15;71(8):2901-15. doi: 10.1158/0008-5472.CAN-10-1731. Epub 2011 Apr 12.
3. Flt3 ligand lessens the growth of tumors obtained after colon cancer cell injection in rats but does not restore tumor-suppressed dendritic cell function. Favre-Felix N, etal., Int J Cancer. 2000 Jun 15;86(6):827-34.
4. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
5. Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model. King GD, etal., Neuro Oncol. 2008 Feb;10(1):19-31. Epub 2007 Dec 13.
6. Potential role of FLT3-ligand in the angiogenic process of multiple myeloma. Kokonozaki M, etal., Leuk Res. 2015 Dec;39(12):1467-72. doi: 10.1016/j.leukres.2015.10.009. Epub 2015 Oct 20.
7. Plasma/serum levels of flt3 ligand are low in normal individuals and highly elevated in patients with Fanconi anemia and acquired aplastic anemia. Lyman SD, etal., Blood. 1995 Dec 1;86(11):4091-6.
8. FLT3 activation improves post-myocardial infarction remodeling involving a cytoprotective effect on cardiomyocytes. Pfister O, etal., J Am Coll Cardiol. 2014 Mar 18;63(10):1011-9. doi: 10.1016/j.jacc.2013.08.1647. Epub 2013 Oct 30.
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Effect of Flt3 ligand gene transfer in experimental pancreatic cancer. Ryschich E, etal., Int J Colorectal Dis. 2007 Feb;22(2):215-23. Epub 2006 Mar 10.
11. Endogenous FLT-3 ligand serum levels are associated with disease stage in patients with myelodysplastic syndromes. Zwierzina H, etal., Leukemia. 1999 Apr;13(4):553-7.
Additional References at PubMed
PMID:7505204   PMID:7566977   PMID:7824267   PMID:8145851   PMID:8180375   PMID:9590652   PMID:9651358   PMID:10637491   PMID:10881197   PMID:11159533   PMID:11710537   PMID:11721383  
PMID:11847009   PMID:11877288   PMID:11956621   PMID:11983110   PMID:12002675   PMID:12036900   PMID:12223523   PMID:12477932   PMID:12676789   PMID:12759428   PMID:12817014   PMID:12969963  
PMID:14670916   PMID:14764540   PMID:15226184   PMID:15489334   PMID:15728521   PMID:15905588   PMID:15914030   PMID:16169070   PMID:16487027   PMID:17949888   PMID:18797870   PMID:18982072  
PMID:19426596   PMID:20142363   PMID:20552015   PMID:20628624   PMID:20933441   PMID:21149635   PMID:21263155   PMID:21505426   PMID:21516120   PMID:21873635   PMID:22110249   PMID:22463758  
PMID:23124877   PMID:24314260   PMID:24419512   PMID:25135299   PMID:25241761   PMID:26559027   PMID:27331411   PMID:28538663   PMID:28917156   PMID:29317685   PMID:29604902   PMID:29695770  
PMID:29892279   PMID:30630980   PMID:31035172   PMID:31175312   PMID:32155324   PMID:32296183   PMID:33369136   PMID:35281004   PMID:35559673   PMID:36081495   PMID:36845082   PMID:37759746  


Genomics

Comparative Map Data
FLT3LG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,474,215 - 49,486,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,474,207 - 49,486,231 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,977,472 - 49,989,488 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,669,298 - 54,681,300 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,669,297 - 54,681,299NCBI
Celera1946,846,847 - 46,858,811 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,355,067 - 46,367,027 (+)NCBIHuRef
CHM1_11949,978,739 - 49,990,762 (+)NCBICHM1_1
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBIT2T-CHM13v2.0
Flt3l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,780,607 - 44,785,914 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,779,212 - 44,785,856 (-)EnsemblGRCm39 Ensembl
GRCm38745,131,183 - 45,136,490 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,129,788 - 45,136,432 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,386,559 - 52,391,802 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,999,456 - 45,004,327 (-)NCBIMGSCv36mm8
Celera740,584,281 - 40,589,522 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.14NCBI
Flt3lg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,751,518 - 104,756,925 (-)NCBIGRCr8
mRatBN7.2195,615,056 - 95,620,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,609,370 - 95,620,463 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,000,447 - 101,005,854 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,473,114 - 109,478,521 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,763,521 - 102,768,928 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,126,006 - 101,131,413 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,124,479 - 101,131,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,190,086 - 102,197,519 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,607,131 - 95,611,290 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera189,873,472 - 89,878,870 (-)NCBICelera
Cytogenetic Map1q22NCBI
Flt3lg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,365,938 - 1,370,002 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,364,056 - 1,371,245 (-)NCBIChiLan1.0ChiLan1.0
FLT3LG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,589,080 - 55,601,931 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,509,418 - 57,522,277 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,486,169 - 46,499,008 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,410,448 - 55,422,545 (+)NCBIpanpan1.1PanPan1.1panPan2
FLT3LG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,015,222 - 107,025,181 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,015,223 - 107,024,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,598,496 - 106,607,982 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,535,285 - 107,544,772 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,535,286 - 107,545,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,208,335 - 107,217,819 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,850,390 - 106,859,883 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,691,506 - 107,700,992 (-)NCBIUU_Cfam_GSD_1.0
Flt3lg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,723,863 - 21,733,400 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,343,491 - 3,350,176 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,343,541 - 3,351,590 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLT3LG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,653,820 - 42,665,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,654,412 - 42,660,458 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,583,397 - 22,594,517 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flt3lg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248324,733,820 - 4,739,214 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FLT3LG
10 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3 copy number gain not provided [RCV001007050] Chr19:44738088..53621561 [GRCh37]
Chr19:19q13.31-13.42		 pathogenic
GRCh37/hg19 19q13.33(chr19:49600909-51366070)x3 copy number gain not provided [RCV000847250] Chr19:49600909..51366070 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_001459.4(FLT3LG):c.611G>A (p.Cys204Tyr) single nucleotide variant Inborn genetic diseases [RCV003272363] Chr19:49480427 [GRCh38]
Chr19:49983684 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_001459.4(FLT3LG):c.33A>G (p.Thr11=) single nucleotide variant not provided [RCV000961668] Chr19:49474672 [GRCh38]
Chr19:49977929 [GRCh37]
Chr19:19q13.33		 benign
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871) copy number gain not provided [RCV001249294] Chr19:47939842..54626871 [GRCh37]
Chr19:19q13.32-13.42		 not provided
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438) copy number gain not specified [RCV002052689] Chr19:49911081..53127438 [GRCh37]
Chr19:19q13.33-13.41		 likely pathogenic
NC_000019.9:g.(?_49519325)_(50366015_?)dup duplication Developmental and epileptic encephalopathy, 12 [RCV002030046] Chr19:49519325..50366015 [GRCh37]
Chr19:19q13.33		 uncertain significance
NC_000019.9:g.(?_48618906)_(50921204_?)dup duplication Developmental and epileptic encephalopathy, 12 [RCV001939968]|not provided [RCV001916178] Chr19:48618906..50921204 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_001459.4(FLT3LG):c.299G>A (p.Arg100His) single nucleotide variant Inborn genetic diseases [RCV002840944] Chr19:49476523 [GRCh38]
Chr19:49979780 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_001459.4(FLT3LG):c.344C>G (p.Pro115Arg) single nucleotide variant Inborn genetic diseases [RCV002764162] Chr19:49478910 [GRCh38]
Chr19:49982167 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_001459.4(FLT3LG):c.541G>T (p.Ala181Ser) single nucleotide variant Inborn genetic diseases [RCV002959350] Chr19:49480357 [GRCh38]
Chr19:49983614 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_001459.4(FLT3LG):c.242G>A (p.Arg81His) single nucleotide variant Inborn genetic diseases [RCV002940074] Chr19:49476466 [GRCh38]
Chr19:49979723 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_001459.4(FLT3LG):c.254G>A (p.Arg85Gln) single nucleotide variant Inborn genetic diseases [RCV002722942] Chr19:49476478 [GRCh38]
Chr19:49979735 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_001459.4(FLT3LG):c.5C>T (p.Thr2Ile) single nucleotide variant Inborn genetic diseases [RCV003218559] Chr19:49474644 [GRCh38]
Chr19:49977901 [GRCh37]
Chr19:19q13.33		 likely benign
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43		 likely pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:48905537-51614930)x3 copy number gain not specified [RCV003986127] Chr19:48905537..51614930 [GRCh37]
Chr19:19q13.33-13.41		 likely pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4351
Count of miRNA genes:983
Interacting mature miRNAs:1221
Transcripts:ENST00000204637, ENST00000344019, ENST00000593422, ENST00000594009, ENST00000595510, ENST00000595815, ENST00000596435, ENST00000597551, ENST00000597914, ENST00000598472, ENST00000598555, ENST00000600084, ENST00000600429, ENST00000601800
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D10S16   No map positions available.
STS-U03858  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19q13.3UniSTS
GeneMap99-GB4 RH Map19270.88UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1330 1125 418 8 676 1 1870 655 646 31 667 709 8 730 1198
Low 1067 1843 1245 555 1077 403 2447 1531 3047 347 733 867 165 1 474 1590 4 2
Below cutoff 41 19 59 57 181 57 40 8 38 38 58 37 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001204502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001204503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001278637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001278638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005258680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005258681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005258682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005258683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006723116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017026532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017026533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017026534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017026535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_935781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_935782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC010619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI792400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC028001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC126293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC136464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB490139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U03858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U29874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000204637   ⟹   ENSP00000204637
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,236 - 49,486,231 (+)Ensembl
RefSeq Acc Id: ENST00000593422
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,583 - 49,476,730 (+)Ensembl
RefSeq Acc Id: ENST00000594009   ⟹   ENSP00000469613
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,561 - 49,486,231 (+)Ensembl
RefSeq Acc Id: ENST00000595510   ⟹   ENSP00000471226
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,602 - 49,482,391 (+)Ensembl
RefSeq Acc Id: ENST00000596435   ⟹   ENSP00000469942
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,228 - 49,486,231 (+)Ensembl
RefSeq Acc Id: ENST00000597551   ⟹   ENSP00000468977
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,215 - 49,486,231 (+)Ensembl
RefSeq Acc Id: ENST00000597914   ⟹   ENSP00000473098
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,478,917 - 49,481,581 (+)Ensembl
RefSeq Acc Id: ENST00000598472
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,476,109 - 49,486,029 (+)Ensembl
RefSeq Acc Id: ENST00000598555   ⟹   ENSP00000469181
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,475,780 - 49,486,231 (+)Ensembl
RefSeq Acc Id: ENST00000600084   ⟹   ENSP00000472628
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,236 - 49,486,231 (+)Ensembl
RefSeq Acc Id: ENST00000600429   ⟹   ENSP00000470453
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,252 - 49,486,151 (+)Ensembl
RefSeq Acc Id: ENST00000601800   ⟹   ENSP00000471860
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,474,207 - 49,486,231 (+)Ensembl
RefSeq Acc Id: NM_001204502   ⟹   NP_001191431
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,215 - 49,486,231 (+)NCBI
GRCh371949,977,455 - 49,989,491 (+)NCBI
HuRef1946,355,067 - 46,367,027 (+)ENTREZGENE
CHM1_11949,978,739 - 49,990,762 (+)NCBI
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001204503   ⟹   NP_001191432
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,586 - 49,486,231 (+)NCBI
GRCh371949,977,455 - 49,989,491 (+)NCBI
HuRef1946,355,067 - 46,367,027 (+)ENTREZGENE
CHM1_11949,979,091 - 49,990,762 (+)NCBI
T2T-CHM13v2.01952,474,559 - 52,486,197 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001278637   ⟹   NP_001265566
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,215 - 49,486,231 (+)NCBI
GRCh371949,977,455 - 49,989,491 (+)NCBI
HuRef1946,355,067 - 46,367,027 (+)NCBI
CHM1_11949,978,739 - 49,990,762 (+)NCBI
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001278638   ⟹   NP_001265567
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,215 - 49,486,231 (+)NCBI
HuRef1946,355,067 - 46,367,027 (+)NCBI
CHM1_11949,978,739 - 49,990,762 (+)NCBI
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001459   ⟹   NP_001450
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,215 - 49,486,231 (+)NCBI
GRCh371949,977,455 - 49,989,491 (+)NCBI
Build 361954,669,298 - 54,681,300 (+)NCBI Archive
HuRef1946,355,067 - 46,367,027 (+)ENTREZGENE
CHM1_11949,978,739 - 49,990,762 (+)NCBI
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006723116   ⟹   XP_006723179
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,603 - 49,481,916 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011526675   ⟹   XP_011524977
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,215 - 49,486,231 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011526676   ⟹   XP_011524978
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,363 - 49,486,231 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011526677   ⟹   XP_011524979
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,603 - 49,486,231 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011526678   ⟹   XP_011524980
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,215 - 49,486,231 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011526680   ⟹   XP_011524982
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,603 - 49,486,231 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047438519   ⟹   XP_047294475
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,603 - 49,486,231 (+)NCBI
RefSeq Acc Id: XM_047438520   ⟹   XP_047294476
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,603 - 49,481,901 (+)NCBI
RefSeq Acc Id: XM_047438521   ⟹   XP_047294477
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,603 - 49,486,231 (+)NCBI
RefSeq Acc Id: XM_047438522   ⟹   XP_047294478
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,215 - 49,486,231 (+)NCBI
RefSeq Acc Id: XM_047438523   ⟹   XP_047294479
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,215 - 49,486,231 (+)NCBI
RefSeq Acc Id: XM_054320357   ⟹   XP_054176332
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,576 - 52,486,197 (+)NCBI
RefSeq Acc Id: XM_054320358   ⟹   XP_054176333
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,576 - 52,481,878 (+)NCBI
RefSeq Acc Id: XM_054320359   ⟹   XP_054176334
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBI
RefSeq Acc Id: XM_054320360   ⟹   XP_054176335
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,336 - 52,486,197 (+)NCBI
RefSeq Acc Id: XM_054320361   ⟹   XP_054176336
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,576 - 52,481,893 (+)NCBI
RefSeq Acc Id: XM_054320362   ⟹   XP_054176337
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,576 - 52,486,197 (+)NCBI
RefSeq Acc Id: XM_054320363   ⟹   XP_054176338
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBI
RefSeq Acc Id: XM_054320364   ⟹   XP_054176339
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,576 - 52,486,197 (+)NCBI
RefSeq Acc Id: XM_054320365   ⟹   XP_054176340
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBI
RefSeq Acc Id: XM_054320366   ⟹   XP_054176341
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBI
RefSeq Acc Id: XM_054320367   ⟹   XP_054176342
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,474,576 - 52,486,197 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001191431 (Get FASTA)   NCBI Sequence Viewer  
  NP_001191432 (Get FASTA)   NCBI Sequence Viewer  
  NP_001265566 (Get FASTA)   NCBI Sequence Viewer  
  NP_001265567 (Get FASTA)   NCBI Sequence Viewer  
  NP_001450 (Get FASTA)   NCBI Sequence Viewer  
  XP_006723179 (Get FASTA)   NCBI Sequence Viewer  
  XP_011524977 (Get FASTA)   NCBI Sequence Viewer  
  XP_011524978 (Get FASTA)   NCBI Sequence Viewer  
  XP_011524979 (Get FASTA)   NCBI Sequence Viewer  
  XP_011524980 (Get FASTA)   NCBI Sequence Viewer  
  XP_011524982 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294475 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294476 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294477 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294478 (Get FASTA)   NCBI Sequence Viewer  
  XP_047294479 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176332 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176333 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176334 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176335 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176336 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176337 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176338 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176339 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176340 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176341 (Get FASTA)   NCBI Sequence Viewer  
  XP_054176342 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA17999 (Get FASTA)   NCBI Sequence Viewer  
  AAA19825 (Get FASTA)   NCBI Sequence Viewer  
  AAA90949 (Get FASTA)   NCBI Sequence Viewer  
  AAA90950 (Get FASTA)   NCBI Sequence Viewer  
  AAH06331 (Get FASTA)   NCBI Sequence Viewer  
  AAH11914 (Get FASTA)   NCBI Sequence Viewer  
  AAH28001 (Get FASTA)   NCBI Sequence Viewer  
  AAI26294 (Get FASTA)   NCBI Sequence Viewer  
  AAI36465 (Get FASTA)   NCBI Sequence Viewer  
  AAI44130 (Get FASTA)   NCBI Sequence Viewer  
  BAG62728 (Get FASTA)   NCBI Sequence Viewer  
  EAW52488 (Get FASTA)   NCBI Sequence Viewer  
  EAW52489 (Get FASTA)   NCBI Sequence Viewer  
  EAW52490 (Get FASTA)   NCBI Sequence Viewer  
  EAW52491 (Get FASTA)   NCBI Sequence Viewer  
  EAW52492 (Get FASTA)   NCBI Sequence Viewer  
  EAW52493 (Get FASTA)   NCBI Sequence Viewer  
  EAW52494 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000204637
  ENSP00000204637.2
  ENSP00000468977
  ENSP00000468977.1
  ENSP00000469181
  ENSP00000469181.1
  ENSP00000469613
  ENSP00000469613.1
  ENSP00000469942.1
  ENSP00000470453
  ENSP00000470453.1
  ENSP00000471226.1
  ENSP00000471860.1
  ENSP00000472628.1
  ENSP00000473098.1
GenBank Protein P49771 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001191431   ⟸   NM_001204502
- Peptide Label: isoform 1 precursor
- UniProtKB: B9EGH2 (UniProtKB/Swiss-Prot),   A0AVC2 (UniProtKB/Swiss-Prot),   Q05C96 (UniProtKB/Swiss-Prot),   P49771 (UniProtKB/Swiss-Prot),   B7ZLY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001450   ⟸   NM_001459
- Peptide Label: isoform 1 precursor
- UniProtKB: B9EGH2 (UniProtKB/Swiss-Prot),   A0AVC2 (UniProtKB/Swiss-Prot),   Q05C96 (UniProtKB/Swiss-Prot),   P49771 (UniProtKB/Swiss-Prot),   B7ZLY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001191432   ⟸   NM_001204503
- Peptide Label: isoform 1 precursor
- UniProtKB: B9EGH2 (UniProtKB/Swiss-Prot),   A0AVC2 (UniProtKB/Swiss-Prot),   Q05C96 (UniProtKB/Swiss-Prot),   P49771 (UniProtKB/Swiss-Prot),   B7ZLY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001265567   ⟸   NM_001278638
- Peptide Label: isoform 2
- UniProtKB: P49771 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001265566   ⟸   NM_001278637
- Peptide Label: isoform 2
- UniProtKB: P49771 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006723179   ⟸   XM_006723116
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011524977   ⟸   XM_011526675
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011524980   ⟸   XM_011526678
- Peptide Label: isoform X6
- UniProtKB: M0QXI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011524978   ⟸   XM_011526676
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011524982   ⟸   XM_011526680
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_011524979   ⟸   XM_011526677
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSP00000471226   ⟸   ENST00000595510
RefSeq Acc Id: ENSP00000469942   ⟸   ENST00000596435
RefSeq Acc Id: ENSP00000468977   ⟸   ENST00000597551
RefSeq Acc Id: ENSP00000473098   ⟸   ENST00000597914
RefSeq Acc Id: ENSP00000469181   ⟸   ENST00000598555
RefSeq Acc Id: ENSP00000204637   ⟸   ENST00000204637
RefSeq Acc Id: ENSP00000472628   ⟸   ENST00000600084
RefSeq Acc Id: ENSP00000470453   ⟸   ENST00000600429
RefSeq Acc Id: ENSP00000471860   ⟸   ENST00000601800
RefSeq Acc Id: ENSP00000469613   ⟸   ENST00000594009
RefSeq Acc Id: XP_047294478   ⟸   XM_047438522
- Peptide Label: isoform X8
RefSeq Acc Id: XP_047294479   ⟸   XM_047438523
- Peptide Label: isoform X9
RefSeq Acc Id: XP_047294475   ⟸   XM_047438519
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047294477   ⟸   XM_047438521
- Peptide Label: isoform X7
RefSeq Acc Id: XP_047294476   ⟸   XM_047438520
- Peptide Label: isoform X2
- UniProtKB: P49771 (UniProtKB/Swiss-Prot),   B9EGH2 (UniProtKB/Swiss-Prot),   A0AVC2 (UniProtKB/Swiss-Prot),   Q05C96 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054176334   ⟸   XM_054320359
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054176338   ⟸   XM_054320363
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054176340   ⟸   XM_054320365
- Peptide Label: isoform X8
RefSeq Acc Id: XP_054176341   ⟸   XM_054320366
- Peptide Label: isoform X9
RefSeq Acc Id: XP_054176335   ⟸   XM_054320360
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054176332   ⟸   XM_054320357
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054176337   ⟸   XM_054320362
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054176339   ⟸   XM_054320364
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054176342   ⟸   XM_054320367
- Peptide Label: isoform X10
RefSeq Acc Id: XP_054176336   ⟸   XM_054320361
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054176333   ⟸   XM_054320358
- Peptide Label: isoform X2
- UniProtKB: P49771 (UniProtKB/Swiss-Prot),   B9EGH2 (UniProtKB/Swiss-Prot),   A0AVC2 (UniProtKB/Swiss-Prot),   Q05C96 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49771-F1-model_v2 AlphaFold P49771 1-235 view protein structure

Promoters
RGD ID:13205137
Promoter ID:EPDNEW_H26149
Type:initiation region
Name:FLT3LG_1
Description:fms related tyrosine kinase 3 ligand
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26150  EPDNEW_H26151  EPDNEW_H26152  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,221 - 49,474,281EPDNEW
RGD ID:13205139
Promoter ID:EPDNEW_H26150
Type:initiation region
Name:FLT3LG_2
Description:fms related tyrosine kinase 3 ligand
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26149  EPDNEW_H26151  EPDNEW_H26152  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,474,586 - 49,474,646EPDNEW
RGD ID:13205141
Promoter ID:EPDNEW_H26151
Type:initiation region
Name:FLT3LG_3
Description:fms related tyrosine kinase 3 ligand
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26149  EPDNEW_H26150  EPDNEW_H26152  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,479,009 - 49,479,069EPDNEW
RGD ID:13205143
Promoter ID:EPDNEW_H26152
Type:initiation region
Name:FLT3LG_4
Description:fms related tyrosine kinase 3 ligand
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26149  EPDNEW_H26150  EPDNEW_H26151  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,480,433 - 49,480,493EPDNEW
RGD ID:6795407
Promoter ID:HG_KWN:30542
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000344019,   NM_001459,   UC002PNV.1,   UC002PNW.1,   UC002PNX.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361954,669,086 - 54,669,687 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3766 AgrOrtholog
COSMIC FLT3LG COSMIC
Ensembl Genes ENSG00000090554 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000204637 ENTREZGENE
  ENST00000204637.6 UniProtKB/Swiss-Prot
  ENST00000594009 ENTREZGENE
  ENST00000594009.5 UniProtKB/Swiss-Prot
  ENST00000595510.1 UniProtKB/Swiss-Prot
  ENST00000596435.5 UniProtKB/TrEMBL
  ENST00000597551 ENTREZGENE
  ENST00000597551.6 UniProtKB/Swiss-Prot
  ENST00000597914.1 UniProtKB/TrEMBL
  ENST00000598555 ENTREZGENE
  ENST00000598555.1 UniProtKB/TrEMBL
  ENST00000600084.5 UniProtKB/TrEMBL
  ENST00000600429 ENTREZGENE
  ENST00000600429.5 UniProtKB/Swiss-Prot
  ENST00000601800.5 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000090554 GTEx
HGNC ID HGNC:3766 ENTREZGENE
Human Proteome Map FLT3LG Human Proteome Map
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flt3_lig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:2323 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 2323 ENTREZGENE
OMIM 600007 OMIM
PANTHER FMS-RELATED TYROSINE KINASE 3 LIGAND UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11032 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Flt3_lig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA28182 PharmGKB
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0AVC2 ENTREZGENE
  B7ZLY4 ENTREZGENE, UniProtKB/TrEMBL
  B9EGH2 ENTREZGENE
  FLT3L_HUMAN UniProtKB/Swiss-Prot
  M0QXI0 ENTREZGENE, UniProtKB/TrEMBL
  M0QYM9_HUMAN UniProtKB/TrEMBL
  M0R2K0_HUMAN UniProtKB/TrEMBL
  M0R3A6_HUMAN UniProtKB/TrEMBL
  P49771 ENTREZGENE
  Q05C96 ENTREZGENE
UniProt Secondary A0AVC2 UniProtKB/Swiss-Prot
  B9EGH2 UniProtKB/Swiss-Prot
  Q05C96 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-10 FLT3LG  fms related receptor tyrosine kinase 3 ligand  FLT3LG  fms related tyrosine kinase 3 ligand  Symbol and/or name change 5135510 APPROVED
2016-01-19 FLT3LG  fms related tyrosine kinase 3 ligand  FLT3LG  fms-related tyrosine kinase 3 ligand  Symbol and/or name change 5135510 APPROVED