Symbol:
Adh1c
Name:
alcohol dehydrogenase 1C (class I), gamma polypeptide
RGD ID:
2044
Description:
Enables all-trans-retinol dehydrogenase (NAD+) activity. Involved in several processes, including animal organ regeneration; response to ethanol; and response to progesterone. Predicted to be located in several cellular components, including ciliary basal body; mitochondrion; and nucleoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in alcohol dependence; late onset Parkinson's disease; and pancreatic cancer. Orthologous to human ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide); ADH1B (alcohol dehydrogenase 1B (class I), beta polypeptide); and ADH1C (alcohol dehydrogenase 1C (class I), gamma polypeptide); INTERACTS WITH (+)-schisandrin B; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 1-naphthyl isothiocyanate.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
Adh; Adh1; Adh1a; Alcohol dehydrogenase (class I), alpha polypeptide; alcohol dehydrogenase 1; alcohol dehydrogenase 1 (class I); alcohol dehydrogenase 1 (class I), gamma polypeptide; alcohol dehydrogenase 1, complex; alcohol dehydrogenase A subunit
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ADH1C (alcohol dehydrogenase 1C (class I), gamma polypeptide) RGD
RGD
Mus musculus (house mouse):
Adh1 (alcohol dehydrogenase 1 (class I)) RGD
RGD
Chinchilla lanigera (long-tailed chinchilla):
Adh1c (alcohol dehydrogenase 1C (class I), gamma polypeptide) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
LOC100970753 (alcohol dehydrogenase 1C) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
LOC100512795 (alcohol dehydrogenase class 4 mu/sigma chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide) HGNC
Ensembl, Inparanoid, OrthoDB, Panther, PhylomeDB
Homo sapiens (human):
ADH1B (alcohol dehydrogenase 1B (class I), beta polypeptide) HGNC
Ensembl, OrthoDB, Panther, PhylomeDB
Homo sapiens (human):
ADH7 (alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide) HGNC
OrthoDB
Homo sapiens (human):
ADH6 (alcohol dehydrogenase 6 (class V)) HGNC
OrthoDB
Alliance orthologs 3
Mus musculus (house mouse):
Adh1 (alcohol dehydrogenase 1 (class I))
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
ADH1C (alcohol dehydrogenase 1C (class I), gamma polypeptide)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
ADH1B (alcohol dehydrogenase 1B (class I), beta polypeptide)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
adh8b (alcohol dehydrogenase 8b)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Danio rerio (zebrafish):
zgc:77938
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Danio rerio (zebrafish):
zgc:63568
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Danio rerio (zebrafish):
adh8a (alcohol dehydrogenase 8a)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Drosophila melanogaster (fruit fly):
Fdh
Alliance
DIOPT (Ensembl Compara|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
H24K24.3
Alliance
DIOPT (Ensembl Compara|PANTHER|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):
SFA1
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
arhgdig
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
adh1b
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER)
Xenopus tropicalis (tropical clawed frog):
adh1a
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Related Pseudogenes:
Adh1-ps1
Is Marker For:
Strains:
SS.MNS-(Adh1-D2Mit5 )/Mco
SS.MNS-(D2Mit6-Adh1 )/Ayd
SS.MNS-(D2Wox27-Adh1 )/Ayd QTLs:
Bp239
Kidm36
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 229,470,703 - 229,482,291 (+) NCBI GRCr8 mRatBN7.2 2 226,797,303 - 226,808,892 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 226,797,303 - 226,808,892 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 2 234,543,562 - 234,555,115 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 232,443,298 - 232,454,851 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 227,307,972 - 227,319,527 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 243,550,655 - 243,562,243 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 243,550,627 - 243,687,857 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 2 262,090,818 - 262,102,977 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 2 235,799,396 - 235,811,584 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 2 235,786,135 - 235,797,838 (+) NCBI Celera 2 218,954,198 - 218,965,645 (+) NCBI Celera Cytogenetic Map 2 q44 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Adh1c Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ADH1 mRNA] CTD PMID:31150632 Adh1c Rat (1->4)-beta-D-glucan multiple interactions ISO Adh1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ADH1 mRNA CTD PMID:36331819 Adh1c Rat 1,2-dimethylhydrazine decreases expression ISO Adh1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of ADH1 mRNA CTD PMID:22206623 Adh1c Rat 1,2-dimethylhydrazine multiple interactions ISO Adh1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADH1 mRNA CTD PMID:22206623 Adh1c Rat 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine decreases expression EXP 6480464 chlorcyclizine results in decreased expression of ADH1 mRNA CTD PMID:21058326 Adh1c Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of ADH1 mRNA CTD PMID:25380136 Adh1c Rat 17alpha-ethynylestradiol increases expression ISO Adh1 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of ADH1 mRNA CTD PMID:17942748 Adh1c Rat 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of ADH1 mRNA CTD PMID:15953391 and PMID:17108234 Adh1c Rat 17alpha-ethynylestradiol multiple interactions ISO Adh1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADH1 mRNA CTD PMID:17942748 Adh1c Rat 17alpha-ethynylestradiol affects expression ISO Adh1 (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of ADH1 mRNA CTD PMID:17555576 Adh1c Rat 17beta-estradiol decreases expression ISO ADH1C (Homo sapiens) 6480464 Estradiol results in decreased expression of ADH1C mRNA CTD PMID:20106945 Adh1c Rat 17beta-estradiol decreases expression ISO Adh1 (Mus musculus) 6480464 Estradiol results in decreased expression of ADH1 mRNA CTD PMID:39298647 Adh1c Rat 17beta-estradiol increases expression ISO Adh1 (Mus musculus) 6480464 Estradiol results in increased expression of ADH1 mRNA CTD PMID:14664709 Adh1c Rat 1H-pyrazole multiple interactions ISO Adh1 (Mus musculus) 6480464 pyrazole inhibits the reaction [ADH1 protein results in increased metabolism of Ethanol] CTD PMID:7646056 Adh1c Rat 1H-pyrazole decreases activity EXP 6480464 pyrazole results in decreased activity of ADH1 protein CTD PMID:15551062 Adh1c Rat 1H-pyrazole decreases activity ISO Adh1 (Mus musculus) 6480464 pyrazole results in decreased activity of ADH1 protein CTD PMID:16289176 Adh1c Rat 2,3,7,8-tetrabromodibenzodioxine decreases expression ISO Adh1 (Mus musculus) 6480464 2 more ... CTD PMID:27604104 Adh1c Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Adh1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADH1 mRNA CTD PMID:17942748 Adh1c Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ADH1 mRNA CTD PMID:34747641 Adh1c Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Adh1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of ADH1 mRNA CTD PMID:28213091 Adh1c Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ADH1 mRNA CTD PMID:18796159 and PMID:21215274 Adh1c Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO ADH1C (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ADH1C mRNA CTD PMID:20106945 and PMID:26159488 Adh1c Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ADH1C mRNA CTD PMID:26159488 Adh1c Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Adh1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ADH1 mRNA CTD PMID:17949056 and PMID:21570461 Adh1c Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO ADH1C (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of ADH1C mRNA CTD PMID:22298810 Adh1c Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Adh1 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Adh1c Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of ADH1 mRNA CTD PMID:21346803 Adh1c Rat 2-butoxyethanol decreases expression ISO Adh1 (Mus musculus) 6480464 n-butoxyethanol results in decreased expression of ADH1 mRNA CTD PMID:19812364 Adh1c Rat 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:34256052 Adh1c Rat 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 AHR gene mutant form inhibits the reaction [3 more ... CTD PMID:34256052 Adh1c Rat 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of ADH1 protein CTD PMID:34915118 Adh1c Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO ADH1C (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ADH1C mRNA CTD PMID:28628672 Adh1c Rat 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of ADH1 mRNA CTD PMID:25380136 Adh1c Rat 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of ADH1 mRNA CTD PMID:30723492 Adh1c Rat 4,4'-sulfonyldiphenol increases expression ISO Adh1 (Mus musculus) 6480464 bisphenol S results in increased expression of ADH1 mRNA CTD PMID:30951980 and PMID:39298647 Adh1c Rat 4-hydroxyphenyl retinamide increases expression ISO Adh1 (Mus musculus) 6480464 Fenretinide results in increased expression of ADH1C mRNA CTD PMID:28973697 Adh1c Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole decreases expression ISO ADH1C (Homo sapiens) 6480464 Omeprazole results in decreased expression of ADH1C mRNA CTD PMID:12040753 Adh1c Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of ADH1 mRNA CTD PMID:30047161 Adh1c Rat acetaldehyde increases chemical synthesis ISO Adh1 (Mus musculus) 6480464 ADH1 protein results in increased chemical synthesis of Acetaldehyde CTD PMID:11893554 Adh1c Rat acetaldehyde multiple interactions ISO ADH1C (Homo sapiens) 6480464 [ADH1C protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde CTD PMID:15138216 Adh1c Rat acetaldehyde multiple interactions ISO Adh1 (Mus musculus) 6480464 [ADH1 protein co-treated with Ethanol] results in increased abundance of Acetaldehyde more ... CTD PMID:11981770 and PMID:7646056 Adh1c Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of ADH1 mRNA CTD PMID:31881176 Adh1c Rat acetone multiple interactions ISO Adh1 (Mus musculus) 6480464 [ADH1 protein results in increased oxidation of allyl alcohol] which results in increased abundance of Acetone CTD PMID:11981770 Adh1c Rat acrolein affects reduction EXP 6480464 ADH1 protein affects the reduction of Acrolein CTD PMID:12604195 Adh1c Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of ADH1 mRNA CTD PMID:28959563 Adh1c Rat aflatoxin B1 affects expression ISO ADH1C (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of ADH1C protein CTD PMID:20106945 Adh1c Rat aflatoxin B1 decreases expression ISO ADH1C (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of ADH1C mRNA CTD PMID:27153756 Adh1c Rat all-trans-retinoic acid increases expression ISO ADH1C (Homo sapiens) 6480464 Tretinoin results in increased expression of ADH1C mRNA CTD PMID:23830798 Adh1c Rat allyl alcohol increases oxidation ISO Adh1 (Mus musculus) 6480464 ADH1 protein results in increased oxidation of allyl alcohol CTD PMID:11981770 Adh1c Rat allyl alcohol multiple interactions ISO Adh1 (Mus musculus) 6480464 [ADH1 protein results in increased oxidation of allyl alcohol] which results in increased abundance of Acetone CTD PMID:11981770 Adh1c Rat alpha-hexachlorocyclohexane decreases expression EXP 6480464 alpha-hexachlorocyclohexane results in decreased expression of ADH1 mRNA CTD PMID:16940010 Adh1c Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of ADH1 mRNA CTD PMID:30047161 Adh1c Rat Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of ADH1 mRNA CTD PMID:18178546 Adh1c Rat atazanavir sulfate multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ADH1C mRNA CTD PMID:33819548 Adh1c Rat Azoxymethane multiple interactions ISO Adh1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADH1 mRNA CTD PMID:29950665 Adh1c Rat benzalkonium chloride decreases expression ISO Adh1 (Mus musculus) 6480464 Benzalkonium Compounds results in decreased expression of ADH1 mRNA CTD PMID:31199489 Adh1c Rat benzene affects expression EXP 6480464 Benzene affects the expression of ADH1 mRNA CTD PMID:15878777 Adh1c Rat benzo[a]pyrene increases mutagenesis ISO ADH1C (Homo sapiens) 6480464 Benzo(a)pyrene results in increased mutagenesis of ADH1C gene CTD PMID:25435355 Adh1c Rat benzo[a]pyrene decreases expression ISO ADH1C (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of ADH1C mRNA CTD PMID:32234424 Adh1c Rat benzo[a]pyrene affects methylation ISO ADH1C (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ADH1C promoter CTD PMID:27901495 Adh1c Rat benzo[a]pyrene increases expression ISO Adh1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of ADH1 mRNA CTD PMID:22228805 Adh1c Rat bifenthrin increases expression ISO Adh1 (Mus musculus) 6480464 bifenthrin results in increased expression of ADH1 mRNA CTD PMID:26071804 Adh1c Rat bis(2-ethylhexyl) phthalate affects expression ISO Adh1 (Mus musculus) 6480464 Diethylhexyl Phthalate affects the expression of ADH1 mRNA CTD PMID:27405655 Adh1c Rat bis(2-ethylhexyl) phthalate decreases expression ISO Adh1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of ADH1 mRNA CTD PMID:34319233 Adh1c Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ADH1 mRNA and bisphenol A results in decreased expression of ADH1C mRNA CTD PMID:22842222 more ... Adh1c Rat bisphenol A decreases expression ISO Adh1 (Mus musculus) 6480464 bisphenol A results in decreased expression of ADH1 mRNA CTD PMID:33221593 Adh1c Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ADH1 mRNA CTD PMID:30903817 Adh1c Rat bisphenol A increases expression ISO ADH1C (Homo sapiens) 6480464 bisphenol A results in increased expression of ADH1C mRNA CTD PMID:29275510 Adh1c Rat bisphenol A increases expression ISO Adh1 (Mus musculus) 6480464 bisphenol A results in increased expression of ADH1 mRNA CTD PMID:30790712 and PMID:30951980 Adh1c Rat bisphenol AF increases expression ISO ADH1C (Homo sapiens) 6480464 bisphenol AF results in increased expression of ADH1C protein CTD PMID:34186270 Adh1c Rat bisphenol F increases expression ISO Adh1 (Mus musculus) 6480464 bisphenol F results in increased expression of ADH1 mRNA CTD PMID:30951980 Adh1c Rat bosentan decreases expression ISO ADH1C (Homo sapiens) 6480464 Bosentan results in decreased expression of ADH1C mRNA and Bosentan results in decreased expression of ADH1C protein CTD PMID:29761207 Adh1c Rat cadmium dichloride increases expression ISO Adh1 (Mus musculus) 6480464 Cadmium Chloride results in increased expression of ADH1 mRNA CTD PMID:24982889 Adh1c Rat carbon nanotube decreases expression ISO Adh1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Adh1c Rat carnosic acid increases expression ISO Adh1 (Mus musculus) 6480464 salvin results in increased expression of ADH1 protein CTD PMID:35926579 Adh1c Rat CGP 52608 multiple interactions ISO ADH1C (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to ADH1C gene] CTD PMID:28238834 Adh1c Rat chenodeoxycholic acid multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ADH1C mRNA more ... CTD PMID:33819548 Adh1c Rat chlordecone increases expression ISO Adh1 (Mus musculus) 6480464 Chlordecone results in increased expression of ADH1 mRNA CTD PMID:33711761 Adh1c Rat chlordecone decreases expression ISO Adh1 (Mus musculus) 6480464 Chlordecone results in decreased expression of ADH1 mRNA CTD PMID:29980752 Adh1c Rat chlorotoluron decreases expression ISO ADH1C (Homo sapiens) 6480464 chlortoluron results in decreased expression of ADH1C mRNA CTD PMID:39207506 Adh1c Rat cimetidine multiple interactions ISO ADH1C (Homo sapiens) 6480464 Cimetidine inhibits the reaction [ADH1C protein results in increased oxidation of Ethanol] CTD PMID:23220590 Adh1c Rat cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of ADH1 protein CTD PMID:22023808 Adh1c Rat clofibrate multiple interactions ISO Adh1 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ADH1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ADH1 mRNA] CTD PMID:17585979 Adh1c Rat clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of ADH1 mRNA CTD PMID:12851107 Adh1c Rat clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ADH1 mRNA CTD PMID:17602206 Adh1c Rat cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of ADH1 mRNA and cobaltous chloride results in increased expression of ADH1 protein CTD PMID:24386269 Adh1c Rat copper atom decreases expression EXP 6480464 Copper results in decreased expression of ADH1 mRNA CTD PMID:22465980 and PMID:30556269 Adh1c Rat copper(0) decreases expression EXP 6480464 Copper results in decreased expression of ADH1 mRNA CTD PMID:22465980 and PMID:30556269 Adh1c Rat crotonaldehyde affects reduction EXP 6480464 ADH1 protein affects the reduction of 2-butenal CTD PMID:12604195 Adh1c Rat cyanamide multiple interactions ISO Adh1 (Mus musculus) 6480464 Cyanamide promotes the reaction [[ADH1 protein co-treated with Ethanol] results in increased abundance of Acetaldehyde] and Cyanamide promotes the reaction [[ADH1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] CTD PMID:11981770 and PMID:7646056 Adh1c Rat cyclosporin A decreases expression ISO ADH1C (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ADH1C mRNA CTD PMID:20106945 Adh1c Rat cyclosporin A multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of ADH1C mRNA CTD PMID:33819548 Adh1c Rat deoxycholic acid multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ADH1C mRNA more ... CTD PMID:33819548 Adh1c Rat dexamethasone increases expression ISO Adh1 (Mus musculus) 6480464 Dexamethasone results in increased expression of ADH1 mRNA CTD PMID:22733784 Adh1c Rat dexamethasone multiple interactions ISO ADH1C (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ADH1C mRNA CTD PMID:28628672 Adh1c Rat dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of ADH1 mRNA CTD PMID:20032058 Adh1c Rat dexamethasone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of ADH1 mRNA] CTD PMID:20032058 Adh1c Rat dexamethasone increases expression ISO ADH1C (Homo sapiens) 6480464 Dexamethasone results in increased expression of ADH1C mRNA CTD PMID:25047013 Adh1c Rat dextran sulfate multiple interactions ISO Adh1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADH1 mRNA CTD PMID:29950665 Adh1c Rat diallyl disulfide multiple interactions ISO Adh1 (Mus musculus) 6480464 diallyl disulfide inhibits the reaction [Ethanol results in decreased expression of ADH1 protein] CTD PMID:35526736 Adh1c Rat dibutyl phthalate multiple interactions ISO Adh1 (Mus musculus) 6480464 [Dibutyl Phthalate results in increased abundance of monobutyl phthalate] which affects the expression of ADH1 mRNA CTD PMID:34175954 Adh1c Rat diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of ADH1 protein CTD PMID:25772430 Adh1c Rat diethyl malate affects expression ISO Adh1 (Mus musculus) 6480464 diethyl malate affects the expression of ADH1 mRNA CTD PMID:24814887 Adh1c Rat diethylstilbestrol decreases expression ISO Adh1 (Mus musculus) 6480464 Diethylstilbestrol results in decreased expression of ADH1 mRNA CTD PMID:15171707 Adh1c Rat diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of ADH1 mRNA CTD PMID:36653537 Adh1c Rat dimethylarsinic acid decreases expression EXP 6480464 Cacodylic Acid results in decreased expression of ADH1 mRNA CTD PMID:37567419 Adh1c Rat dioxygen decreases expression ISO ADH1C (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of ADH1C mRNA CTD PMID:19695866 Adh1c Rat disulfiram decreases activity EXP 6480464 Disulfiram results in decreased activity of ADH1 protein CTD PMID:15551062 Adh1c Rat endosulfan multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ADH1C mRNA CTD PMID:26159488 Adh1c Rat epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of ADH1 mRNA CTD PMID:29038839 Adh1c Rat ethanol multiple interactions ISO Adh1 (Mus musculus) 6480464 [ADH1 protein co-treated with Ethanol] results in increased abundance of Acetaldehyde more ... CTD PMID:11981770 more ... Adh1c Rat ethanol decreases expression ISO Adh1 (Mus musculus) 6480464 Ethanol results in decreased expression of ADH1 mRNA and Ethanol results in decreased expression of ADH1 protein CTD PMID:28119953 and PMID:35526736 Adh1c Rat ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of ADH1C protein CTD PMID:23200777 Adh1c Rat ethanol increases oxidation ISO ADH1C (Homo sapiens) 6480464 ADH1C protein results in increased oxidation of Ethanol CTD PMID:21167143 and PMID:23220590 Adh1c Rat ethanol increases expression ISO ADH1C (Homo sapiens) 6480464 Ethanol results in increased expression of ADH1C mRNA CTD PMID:23300006 Adh1c Rat ethanol affects response to substance ISO ADH1C (Homo sapiens) 6480464 ADH1C gene polymorphism affects the susceptibility to Ethanol CTD PMID:20171022 Adh1c Rat ethanol increases expression ISO Adh1 (Mus musculus) 6480464 Ethanol results in increased expression of ADH1 mRNA and Ethanol results in increased expression of ADH1 protein CTD PMID:22554647 more ... Adh1c Rat ethanol increases metabolic processing ISO ADH1C (Homo sapiens) 6480464 ADH1C protein results in increased metabolism of Ethanol CTD PMID:15138216 and PMID:19822198 Adh1c Rat ethanol increases metabolic processing ISO Adh1 (Mus musculus) 6480464 ADH1 protein results in increased metabolism of Ethanol CTD PMID:7646056 and PMID:7943667 Adh1c Rat ethanol multiple interactions ISO ADH1C (Homo sapiens) 6480464 [ADH1C protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde more ... CTD PMID:15138216 more ... Adh1c Rat ethanol multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Ethanol results in increased expression of ADH1 mRNA] more ... CTD PMID:20705415 and PMID:25111957 Adh1c Rat ethanol increases expression EXP 6480464 Ethanol results in increased expression of ADH1 mRNA CTD PMID:15353170 and PMID:20705415 Adh1c Rat ethylene glycol increases oxidation ISO ADH1C (Homo sapiens) 6480464 ADH1C protein results in increased oxidation of Ethylene Glycol CTD PMID:21167143 Adh1c Rat etomoxir increases expression EXP 6480464 etomoxir results in increased expression of ADH1 mRNA CTD PMID:19234235 Adh1c Rat fenofibrate decreases expression ISO ADH1C (Homo sapiens) 6480464 Fenofibrate results in decreased expression of ADH1C mRNA CTD PMID:25572481 Adh1c Rat fenthion increases expression ISO Adh1 (Mus musculus) 6480464 Fenthion results in increased expression of ADH1 mRNA CTD PMID:34813904 Adh1c Rat fluconazole decreases expression EXP 6480464 Fluconazole results in decreased expression of ADH1 mRNA CTD PMID:16643972 Adh1c Rat fluoranthene multiple interactions ISO Adh1 (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of ADH1 mRNA CTD PMID:28329830 Adh1c Rat folic acid multiple interactions ISO Adh1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADH1 mRNA CTD PMID:22206623 Adh1c Rat fomepizole decreases activity ISO Adh1 (Mus musculus) 6480464 fomepizole results in decreased activity of ADH1 protein CTD PMID:7943667 Adh1c Rat fomepizole multiple interactions ISO ADH1C (Homo sapiens) 6480464 fomepizole inhibits the reaction [ADH1C protein results in increased oxidation of Ethanol] CTD PMID:21167143 Adh1c Rat formaldehyde decreases response to substance EXP 6480464 ADH1 protein results in decreased susceptibility to Formaldehyde CTD PMID:21276436 Adh1c Rat glycochenodeoxycholic acid multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ADH1C mRNA more ... CTD PMID:33819548 Adh1c Rat glycocholic acid multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ADH1C mRNA more ... CTD PMID:33819548 Adh1c Rat glycodeoxycholic acid multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ADH1C mRNA more ... CTD PMID:33819548 Adh1c Rat hydrogen peroxide multiple interactions ISO Adh1 (Mus musculus) 6480464 Hydrogen Peroxide results in decreased expression of and results in decreased activity of ADH1 protein CTD PMID:31870920 Adh1c Rat hydrogen peroxide increases expression ISO Adh1 (Mus musculus) 6480464 Hydrogen Peroxide results in increased expression of ADH1 mRNA CTD PMID:31870920 Adh1c Rat indometacin multiple interactions ISO ADH1C (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ADH1C mRNA CTD PMID:28628672 Adh1c Rat indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of ADH1 mRNA CTD PMID:36868495 Adh1c Rat inulin multiple interactions ISO Adh1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ADH1 mRNA CTD PMID:36331819 Adh1c Rat irinotecan affects expression EXP 6480464 Irinotecan affects the expression of ADH1 mRNA CTD PMID:20097248 Adh1c Rat isoprenaline increases expression ISO Adh1 (Mus musculus) 6480464 Isoproterenol results in increased expression of ADH1 mRNA CTD PMID:20003209 Adh1c Rat ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of ADH1 mRNA CTD PMID:36653537 Adh1c Rat methamphetamine decreases expression ISO Adh1 (Mus musculus) 6480464 Methamphetamine results in decreased expression of ADH1 mRNA CTD PMID:36914120 Adh1c Rat methanol increases oxidation ISO ADH1C (Homo sapiens) 6480464 ADH1C protein results in increased oxidation of Methanol CTD PMID:21167143 Adh1c Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of ADH1 mRNA CTD PMID:30047161 Adh1c Rat mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of ADH1 mRNA CTD PMID:25972201 Adh1c Rat milrinone increases expression EXP 6480464 Milrinone results in increased expression of ADH1 mRNA CTD PMID:22936366 Adh1c Rat Monobutylphthalate multiple interactions ISO Adh1 (Mus musculus) 6480464 [Dibutyl Phthalate results in increased abundance of monobutyl phthalate] which affects the expression of ADH1 mRNA CTD PMID:34175954 Adh1c Rat Muconic dialdehyde increases reduction ISO Adh1 (Mus musculus) 6480464 ADH1 protein results in increased reduction of muconaldehyde CTD PMID:16289176 Adh1c Rat N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Ethanol results in increased expression of ADH1 mRNA] CTD PMID:20705415 Adh1c Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ADH1 mRNA CTD PMID:17602206 Adh1c Rat N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of ADH1 mRNA CTD PMID:25380136 Adh1c Rat N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of ADH1 protein CTD PMID:19716841 Adh1c Rat naphthalene decreases expression EXP 6480464 naphthalene analog results in decreased expression of ADH1 mRNA CTD PMID:24976557 Adh1c Rat nefazodone multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH1C mRNA CTD PMID:33819548 Adh1c Rat nickel atom decreases expression ISO Adh1 (Mus musculus) 6480464 Nickel results in decreased expression of ADH1 mRNA CTD PMID:12540486 Adh1c Rat nitrofen increases expression EXP 6480464 nitrofen results in increased expression of ADH1 mRNA CTD PMID:33484710 Adh1c Rat obeticholic acid decreases expression ISO ADH1C (Homo sapiens) 6480464 obeticholic acid results in decreased expression of ADH1C mRNA CTD PMID:27939613 Adh1c Rat ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of ADH1 mRNA CTD PMID:12700408 Adh1c Rat okadaic acid decreases expression ISO ADH1C (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of ADH1C mRNA and Okadaic Acid results in decreased expression of ADH1C protein CTD PMID:38832940 Adh1c Rat oleanolic acid multiple interactions EXP 6480464 Oleanolic Acid inhibits the reaction [Ethanol results in increased expression of and results in increased activity of ADH1 protein] CTD PMID:25111957 Adh1c Rat omeprazole decreases expression ISO ADH1C (Homo sapiens) 6480464 Omeprazole results in decreased expression of ADH1C mRNA CTD PMID:12040753 Adh1c Rat ouabain affects expression ISO ADH1C (Homo sapiens) 6480464 Ouabain affects the expression of ADH1C protein CTD PMID:17268060 Adh1c Rat p-toluidine increases expression EXP 6480464 4-toluidine results in increased expression of ADH1C mRNA CTD PMID:27638505 Adh1c Rat paracetamol multiple interactions ISO Adh1 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ADH1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ADH1 mRNA] CTD PMID:17585979 Adh1c Rat paracetamol multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of ADH1C mRNA CTD PMID:33819548 Adh1c Rat paracetamol decreases expression ISO ADH1C (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ADH1C mRNA CTD PMID:21420995 Adh1c Rat paracetamol affects expression ISO Adh1 (Mus musculus) 6480464 Acetaminophen affects the expression of ADH1 mRNA CTD PMID:17562736 Adh1c Rat pentachlorophenol multiple interactions ISO ADH1C (Homo sapiens) 6480464 Pentachlorophenol inhibits the reaction [ADH1C protein results in increased metabolism of Ethanol] CTD PMID:19822198 Adh1c Rat perfluorooctane-1-sulfonic acid affects expression ISO Adh1 (Mus musculus) 6480464 perfluorooctane sulfonic acid affects the expression of ADH1 mRNA CTD PMID:19429403 Adh1c Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Adh1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ADH1 mRNA more ... CTD PMID:36331819 Adh1c Rat perfluorooctanoic acid affects expression ISO Adh1 (Mus musculus) 6480464 perfluorooctanoic acid affects the expression of ADH1 mRNA CTD PMID:19429403 Adh1c Rat perfluorooctanoic acid decreases expression ISO ADH1C (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of ADH1C mRNA CTD PMID:27153767 Adh1c Rat phenobarbital decreases expression ISO Adh1 (Mus musculus) 6480464 Phenobarbital results in decreased expression of ADH1 protein CTD PMID:35881160 Adh1c Rat phenobarbital decreases expression ISO ADH1C (Homo sapiens) 6480464 Phenobarbital results in decreased expression of ADH1 protein CTD PMID:35881160 Adh1c Rat pirinixic acid multiple interactions ISO Adh1 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ADH1 mRNA CTD PMID:19710929 Adh1c Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ADH1 mRNA CTD PMID:22112501 Adh1c Rat pirinixic acid increases expression ISO Adh1 (Mus musculus) 6480464 pirinixic acid results in increased expression of ADH1 mRNA CTD PMID:17426115 and PMID:20813756 Adh1c Rat potassium dichromate affects expression ISO Adh1 (Mus musculus) 6480464 Potassium Dichromate affects the expression of ADH1 mRNA CTD PMID:23608068 Adh1c Rat pravastatin decreases expression ISO Adh1 (Mus musculus) 6480464 Pravastatin results in decreased expression of ADH1 mRNA CTD PMID:27225895 Adh1c Rat pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of ADH1 mRNA CTD PMID:27225895 Adh1c Rat pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of ADH1 mRNA CTD PMID:19162173 Adh1c Rat pregnenolone 16alpha-carbonitrile decreases expression ISO Adh1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in decreased expression of ADH1 mRNA CTD PMID:28903501 Adh1c Rat progesterone increases expression ISO ADH1C (Homo sapiens) 6480464 Progesterone results in increased expression of ADH1C mRNA CTD PMID:20864642 Adh1c Rat propan-2-ol increases oxidation ISO Adh1 (Mus musculus) 6480464 ADH1 protein results in increased oxidation of 2-Propanol CTD PMID:11981770 Adh1c Rat propan-2-ol increases oxidation ISO ADH1C (Homo sapiens) 6480464 ADH1C protein results in increased oxidation of 2-Propanol CTD PMID:21167143 Adh1c Rat propanal decreases expression ISO ADH1C (Homo sapiens) 6480464 propionaldehyde results in decreased expression of ADH1C mRNA CTD PMID:26079696 Adh1c Rat raloxifene increases expression EXP 6480464 Raloxifene Hydrochloride results in increased expression of ADH1 mRNA CTD PMID:15576828 Adh1c Rat rifampicin increases expression ISO ADH1C (Homo sapiens) 6480464 Rifampin results in increased expression of ADH1C mRNA CTD PMID:12040753 Adh1c Rat rotenone decreases expression ISO ADH1C (Homo sapiens) 6480464 Rotenone results in decreased expression of ADH1C mRNA CTD PMID:29955902 Adh1c Rat S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 Buthionine Sulfoximine promotes the reaction [Ethanol results in increased expression of ADH1 mRNA] CTD PMID:20705415 Adh1c Rat senecionine increases expression ISO Adh1 (Mus musculus) 6480464 senecionine results in increased expression of ADH1 protein CTD PMID:35357534 Adh1c Rat silicon dioxide decreases expression ISO ADH1C (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of ADH1C mRNA CTD PMID:25895662 Adh1c Rat silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of ADH1 mRNA CTD PMID:32721576 Adh1c Rat sodium arsenite decreases expression ISO ADH1C (Homo sapiens) 6480464 sodium arsenite results in decreased expression of ADH1C mRNA CTD PMID:29301061 Adh1c Rat sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of ADH1 protein CTD PMID:29459688 Adh1c Rat streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of ADH1 mRNA CTD PMID:25905778 Adh1c Rat sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of ADH1 mRNA CTD PMID:30047161 Adh1c Rat Sunset Yellow FCF multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ADH1C mRNA CTD PMID:33819548 Adh1c Rat tamoxifen affects expression ISO Adh1 (Mus musculus) 6480464 Tamoxifen affects the expression of ADH1 mRNA CTD PMID:17555576 Adh1c Rat taraxerone multiple interactions ISO Adh1 (Mus musculus) 6480464 taraxerone promotes the reaction [Ethanol results in increased expression of ADH1 mRNA] CTD PMID:22554647 Adh1c Rat tartrazine multiple interactions ISO ADH1C (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ADH1C mRNA CTD PMID:33819548 Adh1c Rat tauroursodeoxycholic acid decreases expression EXP 6480464 ursodoxicoltaurine results in decreased expression of ADH1 mRNA CTD PMID:15885361 Adh1c Rat testosterone decreases expression ISO Adh1 (Mus musculus) 6480464 Testosterone results in decreased expression of ADH1 mRNA CTD PMID:19693291 Adh1c Rat testosterone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of ADH1 mRNA] CTD PMID:20032058 Adh1c Rat tetrachloroethene decreases expression ISO Adh1 (Mus musculus) 6480464 Tetrachloroethylene results in decreased expression of ADH1 mRNA CTD PMID:28973375 Adh1c Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ADH1 mRNA] CTD PMID:31150632 Adh1c Rat tetrachloromethane decreases expression ISO Adh1 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of ADH1 mRNA CTD PMID:31919559 Adh1c Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ADH1 mRNA CTD PMID:30723492 and PMID:31150632 Adh1c Rat tetrachloromethane multiple interactions ISO Adh1 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of and results in decreased activity of ADH1 protein CTD PMID:31870920 Adh1c Rat titanium dioxide increases expression ISO Adh1 (Mus musculus) 6480464 titanium dioxide results in increased expression of ADH1 mRNA CTD PMID:23131501 Adh1c Rat titanium dioxide multiple interactions ISO Adh1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADH1 mRNA CTD PMID:29950665 Adh1c Rat triadimefon increases expression EXP 6480464 triadimefon results in increased expression of ADH1 mRNA CTD PMID:16643972 Adh1c Rat trichloroethene affects expression ISO Adh1 (Mus musculus) 6480464 Trichloroethylene affects the expression of ADH1 mRNA CTD PMID:29353386 Adh1c Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of ADH1 mRNA CTD PMID:33387578 Adh1c Rat trimellitic anhydride decreases expression ISO Adh1 (Mus musculus) 6480464 trimellitic anhydride results in decreased expression of ADH1 mRNA CTD PMID:19042947 Adh1c Rat triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of ADH1 mRNA CTD PMID:30589522 Adh1c Rat Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of ADH1 mRNA CTD PMID:23639586 Adh1c Rat troglitazone decreases expression ISO ADH1C (Homo sapiens) 6480464 troglitazone results in decreased expression of ADH1C mRNA CTD PMID:25572481 Adh1c Rat valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of ADH1 mRNA CTD PMID:24136188 Adh1c Rat valproic acid decreases expression ISO ADH1C (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ADH1C mRNA and Valproic Acid results in decreased expression of ADH1C protein CTD PMID:29154799 and PMID:29501571 Adh1c Rat valproic acid increases expression ISO Adh1 (Mus musculus) 6480464 Valproic Acid results in increased expression of ADH1 mRNA CTD PMID:24896083 Adh1c Rat valproic acid affects expression ISO Adh1 (Mus musculus) 6480464 Valproic Acid affects the expression of ADH1 mRNA CTD PMID:17292431 Adh1c Rat zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ADH1C mRNA CTD PMID:12672911 Adh1c Rat zinc atom multiple interactions ISO Adh1 (Mus musculus) 6480464 [Zinc co-treated with Ethanol] results in increased expression of ADH1 mRNA CTD PMID:19637192 Adh1c Rat zinc sulfate multiple interactions ISO Adh1 (Mus musculus) 6480464 [Ethanol co-treated with Zinc Sulfate] results in increased activity of ADH1 protein and [Ethanol co-treated with Zinc Sulfate] results in increased expression of ADH1 protein CTD PMID:15920153 Adh1c Rat zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ADH1C mRNA CTD PMID:12672911 Adh1c Rat zinc(0) multiple interactions ISO Adh1 (Mus musculus) 6480464 [Zinc co-treated with Ethanol] results in increased expression of ADH1 mRNA CTD PMID:19637192
(+)-schisandrin B (EXP) (1->4)-beta-D-glucan (ISO) 1,2-dimethylhydrazine (ISO) 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine (EXP) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (ISO) 1H-pyrazole (EXP,ISO) 2,3,7,8-tetrabromodibenzodioxine (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2,4-dinitrotoluene (EXP) 2-butoxyethanol (ISO) 3,3',4,4',5-pentachlorobiphenyl (EXP) 3-chloropropane-1,2-diol (EXP) 3-isobutyl-1-methyl-7H-xanthine (ISO) 4,4'-diaminodiphenylmethane (EXP) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (ISO) 6-propyl-2-thiouracil (EXP) acetaldehyde (ISO) acetamide (EXP) acetone (ISO) acrolein (EXP) acrylamide (EXP) aflatoxin B1 (ISO) all-trans-retinoic acid (ISO) allyl alcohol (ISO) alpha-hexachlorocyclohexane (EXP) amitrole (EXP) Aroclor 1254 (EXP) atazanavir sulfate (ISO) Azoxymethane (ISO) benzalkonium chloride (ISO) benzene (EXP) benzo[a]pyrene (ISO) bifenthrin (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) bisphenol F (ISO) bosentan (ISO) cadmium dichloride (ISO) carbon nanotube (ISO) carnosic acid (ISO) CGP 52608 (ISO) chenodeoxycholic acid (ISO) chlordecone (ISO) chlorotoluron (ISO) cimetidine (ISO) cisplatin (EXP) clofibrate (EXP,ISO) clofibric acid (EXP) cobalt dichloride (EXP) copper atom (EXP) copper(0) (EXP) crotonaldehyde (EXP) cyanamide (ISO) cyclosporin A (ISO) deoxycholic acid (ISO) dexamethasone (EXP,ISO) dextran sulfate (ISO) diallyl disulfide (ISO) dibutyl phthalate (ISO) diclofenac (EXP) diethyl malate (ISO) diethylstilbestrol (EXP,ISO) dimethylarsinic acid (EXP) dioxygen (ISO) disulfiram (EXP) endosulfan (ISO) epoxiconazole (EXP) ethanol (EXP,ISO) ethylene glycol (ISO) etomoxir (EXP) fenofibrate (ISO) fenthion (ISO) fluconazole (EXP) fluoranthene (ISO) folic acid (ISO) fomepizole (ISO) formaldehyde (EXP) glycochenodeoxycholic acid (ISO) glycocholic acid (ISO) glycodeoxycholic acid (ISO) hydrogen peroxide (ISO) indometacin (EXP,ISO) inulin (ISO) irinotecan (EXP) isoprenaline (ISO) ketoconazole (EXP) methamphetamine (ISO) methanol (ISO) methimazole (EXP) mifepristone (EXP) milrinone (EXP) Monobutylphthalate (ISO) Muconic dialdehyde (ISO) N-acetyl-L-cysteine (EXP) N-nitrosodiethylamine (EXP) N-nitrosodimethylamine (EXP) N-nitrosomorpholine (EXP) naphthalene (EXP) nefazodone (ISO) nickel atom (ISO) nitrofen (EXP) obeticholic acid (ISO) ochratoxin A (EXP) okadaic acid (ISO) oleanolic acid (EXP) omeprazole (ISO) ouabain (ISO) p-toluidine (EXP) paracetamol (ISO) pentachlorophenol (ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (ISO) phenobarbital (ISO) pirinixic acid (EXP,ISO) potassium dichromate (ISO) pravastatin (EXP,ISO) pregnenolone 16alpha-carbonitrile (EXP,ISO) progesterone (ISO) propan-2-ol (ISO) propanal (ISO) raloxifene (EXP) rifampicin (ISO) rotenone (ISO) S-butyl-DL-homocysteine (S,R)-sulfoximine (EXP) senecionine (ISO) silicon dioxide (EXP,ISO) sodium arsenite (EXP,ISO) streptozocin (EXP) sulfadimethoxine (EXP) Sunset Yellow FCF (ISO) tamoxifen (ISO) taraxerone (ISO) tartrazine (ISO) tauroursodeoxycholic acid (EXP) testosterone (EXP,ISO) tetrachloroethene (ISO) tetrachloromethane (EXP,ISO) titanium dioxide (ISO) triadimefon (EXP) trichloroethene (EXP,ISO) trimellitic anhydride (ISO) triphenyl phosphate (EXP) Triptolide (EXP) troglitazone (ISO) valdecoxib (EXP) valproic acid (ISO) zinc atom (EXP,ISO) zinc sulfate (ISO) zinc(0) (EXP,ISO)
Biological Process
animal organ regeneration (IEP) behavioral response to ethanol (IEA,ISO) ethanol catabolic process (IEA,ISO) lipid metabolic process (IDA) response to ethanol (IEP) response to progesterone (IEP) response to retinoic acid (IEA,ISO) response to steroid hormone (IEA,ISO) response to testosterone (IEA,ISO) retinoic acid metabolic process (IBA,IEA,ISO) retinoid metabolic process (IEA,ISO) retinol metabolic process (IBA,IEA,ISO)
1.
An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count.
Chen G, etal., Addict Biol. 2017 Nov;22(6):1475-1485. doi: 10.1111/adb.12402. Epub 2016 May 5.
2.
Distribution of alcohol dehydrogenase and the low Km form of aldehyde dehydrogenase in isolated perivenous and periportal hepatocytes in rats.
Chen L, etal., Alcohol Clin Exp Res. 1992 Feb;16(1):23-9.
3.
Structure and expression of the rat class I alcohol dehydrogenase gene.
Crabb DW, etal., Genomics 1989 Nov;5(4):906-14.
4.
High-level expression of rat class I alcohol dehydrogenase is sufficient for ethanol-induced fat accumulation in transduced HeLa cells.
Galli A, etal., Hepatology. 1999 Apr;29(4):1164-70.
5.
Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain.
Galter D, etal., Eur J Biochem 2003 Mar;270(6):1316-26.
6.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
8.
Methanol metabolism and embryotoxicity in rat and mouse conceptuses: comparisons of alcohol dehydrogenase (ADH1), formaldehyde dehydrogenase (ADH3), and catalase.
Harris C, etal., Reprod Toxicol. 2003 May-Jun;17(3):349-57.
9.
Ocular alcohol dehydrogenase in the rat: regional distribution and kinetics of the ADH-1 isoenzyme with retinol and retinal.
Julia P, etal., Exp Eye Res. 1986 Apr;42(4):305-14.
10.
Impact of alcohol consumption with polymorphisms in alcohol-metabolizing enzymes on pancreatic cancer risk in Japanese.
Kanda J, etal., Cancer Sci. 2008 Dec 4.
11.
Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration.
Lopez-Valencia V, etal., Biochem Pharmacol. 2007 Feb 15;73(4):586-96. Epub 2006 Oct 26.
12.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
13.
Interactions of alcohol dehydrogenase to p-hydroxyacetophenone-sepharose and p-acetamidophenol-sepharose.
Negoro M and Wakabayashi I, Alcohol Clin Exp Res. 2005 Dec;29(12 Suppl):304S-8S.
14.
Evidence for the expression of alcohol dehydrogenase class I gene in rat uterus and its up-regulation by progesterone.
Ohno T, etal., Endocr J. 2008 Mar;55(1):83-90. Epub 2008 Jan 24.
15.
OMIM Disease Annotation Pipeline
OMIM Disease Annotation Pipeline
16.
GOA pipeline
RGD automated data pipeline
17.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
19.
Ethanol concentration-dependent alterations in gene expression during acute binge drinking in the HIV-1 transgenic rat.
Sarkar S and Chang SL, Alcohol Clin Exp Res. 2013 Jul;37(7):1082-90. doi: 10.1111/acer.12077. Epub 2013 Feb 15.
20.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Adh1c Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 229,470,703 - 229,482,291 (+) NCBI GRCr8 mRatBN7.2 2 226,797,303 - 226,808,892 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 226,797,303 - 226,808,892 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 2 234,543,562 - 234,555,115 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 232,443,298 - 232,454,851 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 227,307,972 - 227,319,527 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 243,550,655 - 243,562,243 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 243,550,627 - 243,687,857 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 2 262,090,818 - 262,102,977 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 2 235,799,396 - 235,811,584 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 2 235,786,135 - 235,797,838 (+) NCBI Celera 2 218,954,198 - 218,965,645 (+) NCBI Celera Cytogenetic Map 2 q44 NCBI
ADH1C Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 4 99,336,497 - 99,352,746 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 4 99,336,497 - 99,352,746 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 4 100,257,654 - 100,273,903 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 4 100,476,672 - 100,492,940 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 4 100,614,828 - 100,631,081 NCBI Celera 4 97,554,804 - 97,571,075 (-) NCBI Celera Cytogenetic Map 4 q23 NCBI HuRef 4 95,995,418 - 96,011,667 (-) NCBI HuRef CHM1_1 4 100,234,034 - 100,250,392 (-) NCBI CHM1_1 T2T-CHM13v2.0 4 102,651,250 - 102,667,501 (-) NCBI T2T-CHM13v2.0
Adh1 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 3 137,983,346 - 137,996,459 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 3 137,966,752 - 137,996,459 (+) Ensembl GRCm39 Ensembl GRCm38 3 138,277,585 - 138,290,698 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 3 138,260,991 - 138,290,698 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 3 137,940,609 - 137,953,655 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 3 138,215,032 - 138,228,078 (+) NCBI MGSCv36 mm8 Celera 3 144,684,702 - 144,697,775 (+) NCBI Celera Cytogenetic Map 3 G3 NCBI cM Map 3 64.16 NCBI
Adh1c Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 NW_004955496 8,136,279 - 8,149,496 (+) NCBI ChiLan1.0 ChiLan1.0
LOC100970753 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 3 97,415,305 - 97,432,225 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 4 97,698,981 - 97,715,496 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 4 91,756,817 - 91,773,056 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 4 102,418,515 - 102,435,079 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 4 102,388,575 - 102,435,079 (-) Ensembl panpan1.1 panPan2
LOC100512795 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 8 121,020,969 - 121,041,506 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 8 121,020,683 - 121,041,735 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 8 130,164,997 - 130,185,238 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
.
2301408 Kidm36 Kidney mass QTL 36 0.002 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 2 190613715 226808892 Rat 1598813 Memor9 Memory QTL 9 2.7 exploratory behavior trait (VT:0010471) average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674) 2 199341726 234244620 Rat 8693697 Alc36 Alcohol consumption QTL 36 2 0.592 drinking behavior trait (VT:0001422) calculated ethanol drink intake rate (CMO:0001615) 2 217139753 236660713 Rat 1298075 Scl17 Serum cholesterol level QTL 17 3.4 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 2 211744537 249053267 Rat 2298479 Eau5 Experimental allergic uveoretinitis QTL 5 0.0021 uvea integrity trait (VT:0010551) experimental autoimmune uveitis score (CMO:0001504) 2 202446871 237938339 Rat 1354648 Bp239 Blood pressure QTL 239 0.001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 66118463 226797303 Rat 1300126 Bp175 Blood pressure QTL 175 3.46 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 214226044 247136170 Rat 1354649 Kidm17 Kidney mass QTL 17 2.9 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 2 81754530 227146641 Rat 10755499 Bp389 Blood pressure QTL 389 2.61 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 2 18960362 228801039 Rat 7207484 Bss108 Bone structure and strength QTL 108 5.3 femur strength trait (VT:0010010) femur total energy absorbed before break (CMO:0001677) 2 211744537 249053267 Rat 2313073 Bmd75 Bone mineral density QTL 75 4.1 0.0001 tibia mineral mass (VT:1000283) total volumetric bone mineral density (CMO:0001728) 2 215377404 237938339 Rat 7411555 Bw132 Body weight QTL 132 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 2 223389739 249053267 Rat 738013 Alc15 Alcohol consumption QTL 15 4.1 0.00022 consumption behavior trait (VT:0002069) ethanol drink intake rate to body weight ratio (CMO:0001616) 2 184165752 229165752 Rat 61398 Bp50 Blood pressure QTL 50 4.4 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 189599258 234599258 Rat 7207482 Bss107 Bone structure and strength QTL 107 7 femur strength trait (VT:0010010) femur ultimate force (CMO:0001675) 2 211744537 249053267 Rat 1549836 Bss2 Bone structure and strength QTL 2 7.5 femur strength trait (VT:0010010) femur midshaft polar moment of inertia (CMO:0001669) 2 211744537 249053267 Rat 2317752 Glom23 Glomerulus QTL 23 3.6 urine protein amount (VT:0005160) urine protein level (CMO:0000591) 2 193452645 245889826 Rat 2317885 Alcrsp28 Alcohol response QTL 28 2.1 0.63 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 2 212828222 249053267 Rat 1331767 Hrtrt12 Heart rate QTL 12 3.373 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 2 218414747 240841241 Rat 1581499 Esta2 Estrogen-induced thymic atrophy QTL 2 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 2 189599258 226936289 Rat 9589044 Scfw1 Subcutaneous fat weight QTL 1 5.8 0.001 subcutaneous adipose mass (VT:1000472) abdominal subcutaneous fat pad weight (CMO:0002069) 2 182171407 227171407 Rat 8694435 Bw166 Body weight QTL 166 14.08 0.001 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 2 182171407 227171407 Rat 2293833 Kiddil8 Kidney dilation QTL 8 2.9 kidney pelvis morphology trait (VT:0004194) hydronephrosis severity score (CMO:0001208) 2 219753301 247136170 Rat 1598835 Anxrr18 Anxiety related response QTL 18 2.98 body movement coordination trait (VT:0005424) number of rearing movements in an experimental apparatus (CMO:0001752) 2 200990457 245990457 Rat 8694383 Bw158 Body weight QTL 158 7.69 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 2 182171407 227171407 Rat 7207490 Bss111 Bone structure and strength QTL 111 6.4 femur morphology trait (VT:0000559) femur midshaft cortical cross-sectional area (CMO:0001663) 2 211744537 249053267 Rat 8693622 Alc26 Alcohol consumption QTL 26 2.4 0.667 drinking behavior trait (VT:0001422) calculated ethanol drink intake rate (CMO:0001615) 2 221136523 241305619 Rat 2306901 Bp337 Blood pressure QTL 337 0.01 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 164073756 227146641 Rat 61366 Iddm3 Insulin dependent diabetes mellitus QTL 3 4.7 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 2 189599258 234599258 Rat 9587428 Epfw6 Epididymal fat weight QTL 6 7.47 0.001 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 2 223389739 249053267 Rat 8694194 Abfw1 Abdominal fat weight QTL 1 11.7 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 2 182171407 227171407 Rat 2293844 Kiddil7 Kidney dilation QTL 7 3.5 kidney pelvis morphology trait (VT:0004194) hydronephrosis severity score (CMO:0001208) 2 219753301 247136170 Rat 1641891 Alcrsp17 Alcohol response QTL 17 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 2 149559561 249053267 Rat 724534 Uae6 Urinary albumin excretion QTL 6 10 urine albumin amount (VT:0002871) urine albumin level (CMO:0000130) 2 78665619 249053267 Rat
D2Mco31
Rat Assembly Chr Position (strand) Source JBrowse Cytogenetic Map 2 q44 UniSTS
RH127331
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 226,808,361 - 226,808,574 (+) MAPPER mRatBN7.2 Rnor_6.0 2 243,561,713 - 243,561,925 NCBI Rnor6.0 Rnor_5.0 2 262,102,447 - 262,102,659 UniSTS Rnor5.0 RGSC_v3.4 2 235,811,054 - 235,811,266 UniSTS RGSC3.4 Celera 2 218,965,115 - 218,965,327 UniSTS Cytogenetic Map 2 q44 UniSTS
RH94448
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 226,804,370 - 226,804,497 (+) MAPPER mRatBN7.2 mRatBN7.2 2 226,925,460 - 226,925,587 (+) MAPPER mRatBN7.2 Rnor_6.0 2 243,678,784 - 243,678,910 NCBI Rnor6.0 Rnor_6.0 2 243,557,722 - 243,557,848 NCBI Rnor6.0 Rnor_5.0 2 262,215,552 - 262,215,678 UniSTS Rnor5.0 Rnor_5.0 2 262,098,456 - 262,098,582 UniSTS Rnor5.0 RGSC_v3.4 2 235,806,700 - 235,806,826 UniSTS RGSC3.4 RGSC_v3.4 2 235,929,773 - 235,929,899 UniSTS RGSC3.4 Celera 2 219,082,133 - 219,082,259 UniSTS Celera 2 218,961,124 - 218,961,250 UniSTS RH 3.4 Map 2 1605.6 UniSTS Cytogenetic Map 2 q44 UniSTS
AI233003
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 226,808,694 - 226,808,846 (+) MAPPER mRatBN7.2 Rnor_6.0 2 243,562,046 - 243,562,197 NCBI Rnor6.0 Rnor_5.0 2 262,102,780 - 262,102,931 UniSTS Rnor5.0 RGSC_v3.4 2 235,811,387 - 235,811,538 UniSTS RGSC3.4 Celera 2 218,965,448 - 218,965,599 UniSTS RH 3.4 Map 2 1595.4 UniSTS Cytogenetic Map 2 q44 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
3
11
29
70
57
60
41
19
41
146
59
62
35
39
19
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000036993 ⟹ ENSRNOP00000030638
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 2 243,656,579 - 243,687,857 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000083682 ⟹ ENSRNOP00000072955
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 226,799,121 - 226,807,597 (+) Ensembl Rnor_6.0 Ensembl 2 243,550,639 - 243,561,757 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000085067 ⟹ ENSRNOP00000069797
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 226,797,303 - 226,808,892 (+) Ensembl Rnor_6.0 Ensembl 2 243,550,627 - 243,687,383 (+) Ensembl
RefSeq Acc Id:
NM_019286 ⟹ NP_062159
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 229,470,703 - 229,482,291 (+) NCBI mRatBN7.2 2 226,797,303 - 226,808,892 (+) NCBI Rnor_6.0 2 243,550,655 - 243,562,243 (+) NCBI Rnor_5.0 2 262,090,818 - 262,102,977 (+) NCBI RGSC_v3.4 2 235,799,396 - 235,811,584 (+) RGD Celera 2 218,954,198 - 218,965,645 (+) NCBI
Sequence:
TCACTGCAGGAGGGAAGAAGTCTACGAGGATCCATCCATTTCCTGCCCACAGCGAAGGACAGCATGAGCACAGCTGGAAAAGTAATCAAATGCAAAGCGGCCGTGCTATGGGAGCCTCACAAGCCCTT
hide sequence
RefSeq Acc Id:
NP_062159 ⟸ NM_019286
- UniProtKB:
P06757 (UniProtKB/Swiss-Prot), Q8K571 (UniProtKB/TrEMBL)
- Sequence:
MSTAGKVIKCKAAVLWEPHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHAVSGSLFTPLPAVLGHEGAGIVESIGEGVTCVKPGDKVIPLFSPQCGKCRICKHPESNLCCQTKNLTQPKGALLDG
hide sequence
Ensembl Acc Id:
ENSRNOP00000069797 ⟸ ENSRNOT00000085067
Ensembl Acc Id:
ENSRNOP00000030638 ⟸ ENSRNOT00000036993
Ensembl Acc Id:
ENSRNOP00000072955 ⟸ ENSRNOT00000083682
RGD ID: 13691785 Promoter ID: EPDNEW_R2310 Type: multiple initiation site Name: Adh6_1 Description: alcohol dehydrogenase 6 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 2 243,550,657 - 243,550,717 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2023-06-19
Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
Adh1c
alcohol dehydrogenase 1 (class I), gamma polypeptide
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2023-06-09
Adh1c
alcohol dehydrogenase 1 (class I), gamma polypeptide
Adh1
alcohol dehydrogenase 1C (class I), gamma polypeptide
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2022-04-08
Adh1
alcohol dehydrogenase 1C (class I), gamma polypeptide
Adh1
alcohol dehydrogenase 1 (class I)
Name changed
629549 APPROVED
2013-03-07
Adh1
alcohol dehydrogenase 1 (class I)
Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2012-10-01
Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
Adh1
alcohol dehydrogenase 1 (class I)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2010-05-28
Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
Adh1
alcohol dehydrogenase 1 (class I)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2010-05-28
Adh1
alcohol dehydrogenase 1 (class I)
Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2006-03-30
Adh1
alcohol dehydrogenase 1 (class I)
alcohol dehydrogenase 1
Name updated
1299863 APPROVED
2002-11-06
Adh1
alcohol dehydrogenase 1
Alcohol dehydrogenase (class I), alpha polypeptide
Name updated
625702 APPROVED
2002-06-10
Adh1
Alcohol dehydrogenase (class I), alpha polypeptide
Symbol and Name status set to approved
70586 APPROVED
