Advanced Search (OLGA)

Gene: Plekha7 (pleckstrin homology domain containing A7) Rattus norvegicus

Analyze

Symbol:

Plekha7

Name:

pleckstrin homology domain containing A7

RGD ID:

1598216

Description:

Predicted to enable delta-catenin binding activity. Involved in vasodilation. Predicted to be located in cell-cell junction and centrosome. Predicted to be part of pore complex. Predicted to be active in zonula adherens. Used to study glomerulosclerosis and hypertension. Orthologous to human PLEKHA7 (pleckstrin homology domain containing A7); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; amitrole.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC499249; pleckstrin homology domain containing, family A member 7; pleckstrin homology domain-containing family A member 7; RGD1304650; similar to Plekha7 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

Plekha7^em1Mcwi ; Plekha7^em4Mcwi

Genetic Models:

SS-Plekha7^em1Mcwi ; SS-Plekha7^em4Mcwi-/- ; SS-Plekha7^em4Mcwi

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	179,799,040 - 179,982,281 (-)	Ensembl				GRCr8
mRatBN7.2	1	170,364,524 - 170,547,843 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	170,365,135 - 170,547,775 (-)	Ensembl				mRatBN7.2
Rnor_6.0	1	185,427,600 - 185,493,985 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	185,356,975 - 185,538,694 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	192,397,589 - 192,463,974 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	174,249,022 - 174,316,226 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	168,231,482 - 168,298,068 (-)	NCBI		Celera
Cytogenetic Map	1	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

angle-closure glaucoma (ISO)

Cardiac Fibrosis (IMP)

cleft lip (ISO)

glomerulosclerosis (IMP)

hypertension (IMP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

caffeine (ISO)

calcitriol (ISO)

carbamazepine (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

DDE (ISO)

dibenz[a,h]anthracene (ISO)

dichloroacetic acid (ISO)

dicrotophos (ISO)

dimethyl sulfoxide (ISO)

doxorubicin (ISO)

endosulfan (EXP)

fenamidone (ISO)

FR900359 (ISO)

fulvestrant (ISO)

glucose (ISO)

methimazole (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N,N-diethyl-m-toluamide (EXP)

nickel sulfate (ISO)

nitrofen (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP)

phenethyl isothiocyanate (ISO)

potassium chromate (ISO)

potassium dichromate (ISO)

progesterone (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

temozolomide (ISO)

titanium dioxide (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell-cell adhesion mediated by cadherin (IEA,ISO)

epithelial cell-cell adhesion (ISO)

pore complex assembly (IEA,ISO)

vasodilation (IMP)

zonula adherens maintenance (ISO)

Cellular Component

cell junction (IEA,ISO)

cell-cell junction (IEA,ISO)

centrosome (ISO)

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO)

pore complex (IEA,ISO)

zonula adherens (ISO)

Molecular Function

delta-catenin binding (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

E-cadherin signaling pathway (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased susceptibility to hypertension (IMP)

decreased systemic vascular resistance (IMP)

decreased urine albumin level (IMP)

decreased urine protein level (IMP)

increased cardiac output (IMP)

increased cardiac stroke volume (IMP)

increased vasodilation (IMP)

salt-sensitive hypertension (IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat.	Endres BT, etal., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:15632090	PMID:19041755	PMID:19056867	PMID:21454477	PMID:23990464	PMID:30463011

Genomics

Comparative Map Data

Plekha7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	179,799,040 - 179,982,281 (-)	Ensembl				GRCr8
mRatBN7.2	1	170,364,524 - 170,547,843 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	170,365,135 - 170,547,775 (-)	Ensembl				mRatBN7.2
Rnor_6.0	1	185,427,600 - 185,493,985 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	185,356,975 - 185,538,694 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	192,397,589 - 192,463,974 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	174,249,022 - 174,316,226 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	168,231,482 - 168,298,068 (-)	NCBI		Celera
Cytogenetic Map	1	q35	NCBI

PLEKHA7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	16,777,297 - 17,014,414 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	16,777,297 - 17,014,420 (-)	Ensembl			hg38	GRCh38
GRCh37	11	16,798,844 - 17,035,961 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	16,765,786 - 16,992,535 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	16,765,787 - 16,992,535	NCBI
Celera	11	16,936,331 - 17,162,547 (-)	NCBI		Celera
Cytogenetic Map	11	p15.2-p15.1	NCBI
HuRef	11	16,493,736 - 16,718,829 (-)	NCBI		HuRef
CHM1_1	11	16,808,365 - 17,035,019 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	16,874,672 - 17,111,588 (-)	NCBI		T2T-CHM13v2.0

Plekha7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	115,722,722 - 115,907,617 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	115,722,720 - 115,907,611 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	116,123,485 - 116,308,383 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	116,123,485 - 116,308,376 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	123,267,632 - 123,333,355 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	115,915,267 - 115,980,990 (-)	NCBI		MGSCv36	mm8
Celera	7	116,070,352 - 116,128,150 (-)	NCBI		Celera
Cytogenetic Map	7	F1	NCBI
cM Map	7	61.42	NCBI

Plekha7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	31,655,391 - 31,784,002 (-)	Ensembl
ChiLan1.0	NW_004955414	31,655,391 - 31,784,009 (-)	NCBI	ChiLan1.0	ChiLan1.0

PLEKHA7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	19,140,106 - 19,374,232 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	19,100,993 - 19,335,143 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	16,861,464 - 17,095,610 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	16,550,032 - 16,780,558 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	16,555,368 - 16,647,075 (-)	Ensembl			panPan2	panpan1.1

PLEKHA7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	39,426,313 - 39,564,683 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	39,427,401 - 39,645,585 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	38,926,739 - 39,146,021 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	40,530,499 - 40,749,997 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	40,530,553 - 40,751,380 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	39,544,090 - 39,763,976 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	39,750,951 - 39,970,185 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	40,089,812 - 40,309,507 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Plekha7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	46,021,866 - 46,185,642 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936528	2,092,746 - 2,218,870 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936528	2,093,233 - 2,219,622 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLEKHA7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	42,081,541 - 42,311,548 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	42,081,546 - 42,311,526 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	45,136,385 - 45,348,300 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLEKHA7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	47,933,468 - 48,155,749 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	145,372,350 - 145,604,357 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plekha7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	8,421,188 - 8,655,236 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624766	8,421,069 - 8,655,016 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Plekha7
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	85,274,378 - 85,455,140 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Plekha7
1809 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	68
Count of miRNA genes:	63
Interacting mature miRNAs:	64
Transcripts:	ENSRNOT00000064706
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	137611478	182611478	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	153679879	198679879	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	177339686	222339686	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	132760429	191848948	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	153679879	205813246	Rat
8694166	Bw147	Body weight QTL 147	6.83	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	1	153788989	198788989	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	142582336	182383862	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	160573753	210707719	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	160573753	210707719	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	165278545	210278545	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	161077990	206077990	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	168063662	213063662	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	159894717	207261263	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	163992710	208992710	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	155359438	194575574	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	140833106	185833106	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	153679879	232414077	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	160574007	235238518	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	132760429	191848948	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	162753891	207753891	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	153680016	182383862	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	153680016	183564652	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	172718770	228180370	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
2312558	Glom17	Glomerulus QTL 17	3.9	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	175967553	200707874	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	178547286	206690557	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
1582204	Livw1	Liver weight QTL 1	3.6	0.0003	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	1	170078537	182384005	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	210707719	Rat
1576310	Schws2	Schwannoma susceptibility QTL 2		0.029	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	1	153788989	198788989	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	165707719	210707719	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	173363824	227535316	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	180021436	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	191190115	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	132966869	206393015	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	140915717	185915717	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	132760429	191848948	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat
7411599	Foco11	Food consumption QTL 11	18.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	1	153788989	198788989	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	210707719	Rat

Markers in Region

D1Uia11

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	179,843,720 - 179,843,918 (+)	Marker Load Pipeline
mRatBN7.2	1	170,409,393 - 170,409,595 (-)	MAPPER	mRatBN7.2
Rnor_6.0	1	185,494,248 - 185,494,449	NCBI	Rnor6.0
Rnor_5.0	1	192,464,237 - 192,464,438	UniSTS	Rnor5.0
RGSC_v3.4	1	174,248,558 - 174,248,759	UniSTS	RGSC3.4
RGSC_v3.4	1	174,248,557 - 174,248,759	RGD	RGSC3.4
Celera	1	168,231,018 - 168,231,219	UniSTS
RGSC_v3.1	1	174,387,803 - 174,388,005	RGD
Cytogenetic Map	1	q34	UniSTS

RH128343

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	170,375,022 - 170,375,239 (-)	MAPPER	mRatBN7.2
Rnor_6.0	1	185,528,902 - 185,529,118	NCBI	Rnor6.0
Rnor_5.0	1	192,495,714 - 192,495,930	UniSTS	Rnor5.0
RGSC_v3.4	1	174,214,192 - 174,214,408	UniSTS	RGSC3.4
Celera	1	168,199,748 - 168,199,964	UniSTS
RH 3.4 Map	1	1562.3	UniSTS
Cytogenetic Map	1	q34	UniSTS

D5S2405

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	170,438,681 - 170,439,326 (-)	MAPPER	mRatBN7.2
Rnor_6.0	1	185,464,521 - 185,465,165	NCBI	Rnor6.0
Rnor_5.0	1	192,434,510 - 192,435,154	UniSTS	Rnor5.0
RGSC_v3.4	1	174,278,476 - 174,279,120	UniSTS	RGSC3.4
Celera	1	168,260,353 - 168,260,997	UniSTS
Cytogenetic Map	1	q34	UniSTS

Genetic Models

This gene Plekha7 is modified in the following models/strains:

SS-Plekha7^em1Mcwi SS-Plekha7^em4Mcwi-/- SS-Plekha7^em4Mcwi

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001144861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432446	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432447	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432451	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101149	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279471	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279480	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279492	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279505	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000064706 ⟹ ENSRNOP00000059811

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	179,803,372 - 179,982,281 (-)	Ensembl
mRatBN7.2 Ensembl	1	170,369,040 - 170,433,927 (-)	Ensembl
Rnor_6.0 Ensembl	1	185,427,736 - 185,487,594 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086681 ⟹ ENSRNOP00000074003

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	179,799,040 - 179,982,281 (-)	Ensembl
mRatBN7.2 Ensembl	1	170,365,135 - 170,434,130 (-)	Ensembl
Rnor_6.0 Ensembl	1	185,356,975 - 185,538,694 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097576 ⟹ ENSRNOP00000088208

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	179,799,141 - 179,910,816 (-)	Ensembl
mRatBN7.2 Ensembl	1	170,365,135 - 170,476,372 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102237 ⟹ ENSRNOP00000086270

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	179,802,164 - 179,910,816 (-)	Ensembl
mRatBN7.2 Ensembl	1	170,368,413 - 170,547,775 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103236 ⟹ ENSRNOP00000083710

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	170,374,926 - 170,547,775 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110407 ⟹ ENSRNOP00000094927

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	179,799,234 - 179,982,129 (-)	Ensembl
mRatBN7.2 Ensembl	1	170,365,135 - 170,547,775 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115676 ⟹ ENSRNOP00000085633

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	179,809,534 - 179,862,449 (-)	Ensembl
mRatBN7.2 Ensembl	1	170,374,926 - 170,434,005 (-)	Ensembl

RefSeq Acc Id:

XM_039101137 ⟹ XP_038957065

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101139 ⟹ XP_038957067

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,800,024 - 179,982,155 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101140 ⟹ XP_038957068

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101141 ⟹ XP_038957069

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101142 ⟹ XP_038957070

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101146 ⟹ XP_038957074

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101147 ⟹ XP_038957075

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,910,896 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,477,261 (-)	NCBI

RefSeq Acc Id:

XM_039101148 ⟹ XP_038957076

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101149 ⟹ XP_038957077

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,941,928 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,507,438 (-)	NCBI

RefSeq Acc Id:

XM_039101150 ⟹ XP_038957078

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,800,027 - 179,982,155 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101151 ⟹ XP_038957079

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,154 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101152 ⟹ XP_038957080

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,154 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,547,842 (-)	NCBI

RefSeq Acc Id:

XM_039101153 ⟹ XP_038957081

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,877,958 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,443,565 (-)	NCBI

RefSeq Acc Id:

XM_039101155 ⟹ XP_038957083

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,852,775 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,418,452 (-)	NCBI

RefSeq Acc Id:

XM_039101157 ⟹ XP_038957085

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,910,887 (-)	NCBI
mRatBN7.2	1	170,364,524 - 170,476,630 (-)	NCBI

RefSeq Acc Id:

XM_063279471 ⟹ XP_063135541

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,800,024 - 179,982,155 (-)	NCBI

RefSeq Acc Id:

XM_063279480 ⟹ XP_063135550

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI

RefSeq Acc Id:

XM_063279483 ⟹ XP_063135553

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,802,164 - 179,982,155 (-)	NCBI

RefSeq Acc Id:

XM_063279486 ⟹ XP_063135556

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,800,033 - 179,982,155 (-)	NCBI

RefSeq Acc Id:

XM_063279492 ⟹ XP_063135562

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,154 (-)	NCBI

RefSeq Acc Id:

XM_063279495 ⟹ XP_063135565

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,800,024 - 179,982,155 (-)	NCBI

RefSeq Acc Id:

XM_063279498 ⟹ XP_063135568

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,155 (-)	NCBI

RefSeq Acc Id:

XM_063279505 ⟹ XP_063135575

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,950,728 (-)	NCBI

RefSeq Acc Id:

XM_063279508 ⟹ XP_063135578

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,798,856 - 179,982,154 (-)	NCBI

RefSeq Acc Id:

XM_063279520 ⟹ XP_063135590

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	179,800,024 - 179,910,889 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001419375	(Get FASTA)	NCBI Sequence Viewer
	NP_001419376	(Get FASTA)	NCBI Sequence Viewer
	NP_001419377	(Get FASTA)	NCBI Sequence Viewer
	NP_001419378	(Get FASTA)	NCBI Sequence Viewer
	NP_001419379	(Get FASTA)	NCBI Sequence Viewer
	NP_001419380	(Get FASTA)	NCBI Sequence Viewer
	NP_001419381	(Get FASTA)	NCBI Sequence Viewer
	NP_001419382	(Get FASTA)	NCBI Sequence Viewer
	XP_038957065	(Get FASTA)	NCBI Sequence Viewer
	XP_038957067	(Get FASTA)	NCBI Sequence Viewer
	XP_038957068	(Get FASTA)	NCBI Sequence Viewer
	XP_038957069	(Get FASTA)	NCBI Sequence Viewer
	XP_038957070	(Get FASTA)	NCBI Sequence Viewer
	XP_038957074	(Get FASTA)	NCBI Sequence Viewer
	XP_038957075	(Get FASTA)	NCBI Sequence Viewer
	XP_038957076	(Get FASTA)	NCBI Sequence Viewer
	XP_038957077	(Get FASTA)	NCBI Sequence Viewer
	XP_038957078	(Get FASTA)	NCBI Sequence Viewer
	XP_038957079	(Get FASTA)	NCBI Sequence Viewer
	XP_038957080	(Get FASTA)	NCBI Sequence Viewer
	XP_038957081	(Get FASTA)	NCBI Sequence Viewer
	XP_038957083	(Get FASTA)	NCBI Sequence Viewer
	XP_038957085	(Get FASTA)	NCBI Sequence Viewer
	XP_063135541	(Get FASTA)	NCBI Sequence Viewer
	XP_063135550	(Get FASTA)	NCBI Sequence Viewer
	XP_063135553	(Get FASTA)	NCBI Sequence Viewer
	XP_063135556	(Get FASTA)	NCBI Sequence Viewer
	XP_063135562	(Get FASTA)	NCBI Sequence Viewer
	XP_063135565	(Get FASTA)	NCBI Sequence Viewer
	XP_063135568	(Get FASTA)	NCBI Sequence Viewer
	XP_063135575	(Get FASTA)	NCBI Sequence Viewer
	XP_063135578	(Get FASTA)	NCBI Sequence Viewer
	XP_063135590	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM17741	(Get FASTA)	NCBI Sequence Viewer
	EDM17742	(Get FASTA)	NCBI Sequence Viewer
	EDM17743	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000059811
	ENSRNOP00000059811.4
	ENSRNOP00000074003
	ENSRNOP00000074003.3
	ENSRNOP00000085633
	ENSRNOP00000085633.2
	ENSRNOP00000086270
	ENSRNOP00000086270.2
	ENSRNOP00000088208
	ENSRNOP00000088208.2
	ENSRNOP00000094927
	ENSRNOP00000094927.2

Ensembl Acc Id:

ENSRNOP00000074003 ⟸ ENSRNOT00000086681

Ensembl Acc Id:

ENSRNOP00000059811 ⟸ ENSRNOT00000064706

RefSeq Acc Id:	XP_038957079 ⟸ XM_039101151
- Peptide Label:	isoform X13
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957080 ⟸ XM_039101152
- Peptide Label:	isoform X17

RefSeq Acc Id:	XP_038957074 ⟸ XM_039101146
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957069 ⟸ XM_039101141
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957078 ⟸ XM_039101150
- Peptide Label:	isoform X12
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957068 ⟸ XM_039101140
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957076 ⟸ XM_039101148
- Peptide Label:	isoform X9
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957065 ⟸ XM_039101137
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957070 ⟸ XM_039101142
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957067 ⟸ XM_039101139
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957077 ⟸ XM_039101149
- Peptide Label:	isoform X10
- UniProtKB:	D3ZRT6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957075 ⟸ XM_039101147
- Peptide Label:	isoform X8
- UniProtKB:	D3ZRT6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957085 ⟸ XM_039101157
- Peptide Label:	isoform X22
- UniProtKB:	A0A8I6A7D6 (UniProtKB/TrEMBL), D3ZRT6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957081 ⟸ XM_039101153
- Peptide Label:	isoform X18
- UniProtKB:	D3ZRT6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957083 ⟸ XM_039101155
- Peptide Label:	isoform X20
- UniProtKB:	D3ZRT6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000083710 ⟸ ENSRNOT00000103236

Ensembl Acc Id:

ENSRNOP00000085633 ⟸ ENSRNOT00000115676

Ensembl Acc Id:

ENSRNOP00000094927 ⟸ ENSRNOT00000110407

Ensembl Acc Id:

ENSRNOP00000088208 ⟸ ENSRNOT00000097576

Ensembl Acc Id:

ENSRNOP00000086270 ⟸ ENSRNOT00000102237

RefSeq Acc Id:	XP_063135568 ⟸ XM_063279498
- Peptide Label:	isoform X16
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135550 ⟸ XM_063279480
- Peptide Label:	isoform X11
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135578 ⟸ XM_063279508
- Peptide Label:	isoform X19

RefSeq Acc Id:	XP_063135562 ⟸ XM_063279492
- Peptide Label:	isoform X14

RefSeq Acc Id:	XP_063135575 ⟸ XM_063279505
- Peptide Label:	isoform X18
- UniProtKB:	D3ZRT6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135565 ⟸ XM_063279495
- Peptide Label:	isoform X15
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135541 ⟸ XM_063279471
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135590 ⟸ XM_063279520
- Peptide Label:	isoform X21
- UniProtKB:	D3ZRT6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135556 ⟸ XM_063279486
- Peptide Label:	isoform X12
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135553 ⟸ XM_063279483
- Peptide Label:	isoform X12
- UniProtKB:	A0A8I6A1V7 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K6Z8-F1-model_v2	AlphaFold	A0A0G2K6Z8	1-1193	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1598216	AgrOrtholog
BioCyc Gene	G2FUF-57721	BioCyc
Ensembl Genes	ENSRNOG00000024602	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000064706	ENTREZGENE
	ENSRNOT00000064706.4	UniProtKB/TrEMBL
	ENSRNOT00000086681	ENTREZGENE
	ENSRNOT00000086681.3	UniProtKB/TrEMBL
	ENSRNOT00000097576	ENTREZGENE
	ENSRNOT00000097576.2	UniProtKB/TrEMBL
	ENSRNOT00000102237	ENTREZGENE
	ENSRNOT00000102237.2	UniProtKB/TrEMBL
	ENSRNOT00000110407	ENTREZGENE
	ENSRNOT00000110407.2	UniProtKB/TrEMBL
	ENSRNOT00000115676	ENTREZGENE
	ENSRNOT00000115676.2	UniProtKB/TrEMBL
Gene3D-CATH	2.20.70.10	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
InterPro	PH_type	UniProtKB/TrEMBL
	PKHA4/5/6/7_PH	UniProtKB/TrEMBL
	Pleckstrin_homology	UniProtKB/TrEMBL
	WW_dom	UniProtKB/TrEMBL
	WW_dom_sf	UniProtKB/TrEMBL
NCBI Gene	499249	ENTREZGENE
PANTHER	PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN	UniProtKB/TrEMBL
	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7	UniProtKB/TrEMBL
Pfam	PF00169	UniProtKB/TrEMBL
	TBCA_PH	UniProtKB/TrEMBL
PhenoGen	Plekha7	PhenoGen
PROSITE	PH_DOMAIN	UniProtKB/TrEMBL
	WW_DOMAIN_1	UniProtKB/TrEMBL
	WW_DOMAIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000024602	RatGTEx
SMART	SM00233	UniProtKB/TrEMBL
	SM00456	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	SSF51045	UniProtKB/TrEMBL
UniProt	A0A0G2K6Z8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZXL6	ENTREZGENE
	A0A8I6A1V7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A229	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A7D6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GKY3	ENTREZGENE, UniProtKB/TrEMBL
	D3ZRT6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-05	Plekha7	pleckstrin homology domain containing, family A member 7	LOC499249	similar to Plekha7 protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC499249	similar to Plekha7 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

Mammalian Phenotype

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

Mammalian Phenotype