Plekha7 (pleckstrin homology domain containing A7) - Rat Genome Database

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Gene: Plekha7 (pleckstrin homology domain containing A7) Ictidomys tridecemlineatus
Analyze
Symbol: Plekha7
Name: pleckstrin homology domain containing A7
RGD ID: 12703254
Description: ENCODES a protein that exhibits delta-catenin binding (ortholog); INVOLVED IN vasodilation (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ASSOCIATED WITH angle-closure glaucoma (ortholog); Cardiac Fibrosis (ortholog); cleft lip (ortholog); FOUND IN centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain containing A7, transcript variant X1; pleckstrin homology domain containing A7, transcript variant X2; pleckstrin homology domain containing A7, transcript variant X3; pleckstrin homology domain containing A7, transcript variant X4; pleckstrin homology domain containing A7, transcript variant X5; pleckstrin homology domain-containing family A member 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494746,021,866 - 46,185,642 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365282,092,746 - 2,218,870 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365282,093,233 - 2,219,622 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Plekha7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494746,021,866 - 46,185,642 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365282,092,746 - 2,218,870 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365282,093,233 - 2,219,622 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381116,777,297 - 17,014,414 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1116,777,297 - 17,014,415 (-)EnsemblGRCh38hg38GRCh38
GRCh371116,798,844 - 17,035,961 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361116,765,786 - 16,992,535 (-)NCBINCBI36Build 36hg18NCBI36
Build 341116,765,787 - 16,992,535NCBI
Celera1116,936,331 - 17,162,547 (-)NCBICelera
Cytogenetic Map11p15.2-p15.1NCBI
HuRef1116,493,736 - 16,718,829 (-)NCBIHuRef
CHM1_11116,808,365 - 17,035,019 (-)NCBICHM1_1
T2T-CHM13v2.01116,874,672 - 17,111,588 (-)NCBIT2T-CHM13v2.0
Plekha7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397115,722,722 - 115,907,617 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7115,722,720 - 115,907,611 (-)EnsemblGRCm39 Ensembl
GRCm387116,123,485 - 116,308,383 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7116,123,485 - 116,308,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv377123,267,632 - 123,333,355 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367115,915,267 - 115,980,990 (-)NCBIMGSCv36mm8
Celera7116,070,352 - 116,128,150 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map761.42NCBI
Plekha7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,798,856 - 179,982,155 (-)NCBIGRCr8
mRatBN7.21170,364,524 - 170,547,843 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1170,365,135 - 170,547,775 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01185,427,600 - 185,493,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1185,356,975 - 185,538,694 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01192,397,589 - 192,463,974 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,249,022 - 174,316,226 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1168,231,482 - 168,298,068 (-)NCBICelera
Cytogenetic Map1q35NCBI
Plekha7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541431,655,391 - 31,784,002 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541431,655,391 - 31,784,009 (-)NCBIChiLan1.0ChiLan1.0
PLEKHA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2919,140,106 - 19,374,232 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11119,100,993 - 19,335,143 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01116,861,464 - 17,095,610 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11116,550,032 - 16,780,558 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1116,555,368 - 16,647,075 (-)Ensemblpanpan1.1panPan2
PLEKHA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12139,426,313 - 39,564,683 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2139,427,401 - 39,645,585 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2138,926,739 - 39,146,021 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02140,530,499 - 40,749,997 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2140,530,553 - 40,751,380 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12139,544,090 - 39,763,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02139,750,951 - 39,970,185 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02140,089,812 - 40,309,507 (-)NCBIUU_Cfam_GSD_1.0
PLEKHA7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl242,081,541 - 42,311,548 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1242,081,546 - 42,311,526 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2245,136,385 - 45,348,300 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1147,933,468 - 48,155,749 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038145,372,350 - 145,604,357 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247668,421,188 - 8,655,236 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247668,421,069 - 8,655,016 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005326763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040284694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005733619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005733620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000001427   ⟹   ENSSTOP00000001280
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365282,092,746 - 2,218,180 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000028593   ⟹   ENSSTOP00000022428
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365282,137,711 - 2,218,870 (+)Ensembl
RefSeq Acc Id: XM_040284677   ⟹   XP_040140611
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,484 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284678   ⟹   XP_040140612
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,097,645 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284679   ⟹   XP_040140613
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,484 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284681   ⟹   XP_040140615
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,484 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284682   ⟹   XP_040140616
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,484 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284683   ⟹   XP_040140617
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,484 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284684   ⟹   XP_040140618
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,109,526 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284685   ⟹   XP_040140619
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,108,706 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284686   ⟹   XP_040140620
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,484 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284687   ⟹   XP_040140621
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,059,243 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284688   ⟹   XP_040140622
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,493 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284689   ⟹   XP_040140623
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,021,866 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284690   ⟹   XP_040140624
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,101,345 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284691   ⟹   XP_040140625
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,485 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284692   ⟹   XP_040140626
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,485 - 46,185,642 (+)NCBI
RefSeq Acc Id: XM_040284693   ⟹   XP_040140627
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,483 - 46,174,207 (+)NCBI
RefSeq Acc Id: XM_040284694   ⟹   XP_040140628
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,483 - 46,174,204 (+)NCBI
RefSeq Acc Id: XR_005733619
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,484 - 46,185,642 (+)NCBI
RefSeq Acc Id: XR_005733620
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494746,058,484 - 46,185,642 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_040140623   ⟸   XM_040284689
- Peptide Label: isoform X10
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140627   ⟸   XM_040284693
- Peptide Label: isoform X13
RefSeq Acc Id: XP_040140628   ⟸   XM_040284694
- Peptide Label: isoform X13
RefSeq Acc Id: XP_040140611   ⟸   XM_040284677
- Peptide Label: isoform X1
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140615   ⟸   XM_040284681
- Peptide Label: isoform X4
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140616   ⟸   XM_040284682
- Peptide Label: isoform X5
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140613   ⟸   XM_040284679
- Peptide Label: isoform X3
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140617   ⟸   XM_040284683
- Peptide Label: isoform X6
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140620   ⟸   XM_040284686
- Peptide Label: isoform X9
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140625   ⟸   XM_040284691
- Peptide Label: isoform X11
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140626   ⟸   XM_040284692
- Peptide Label: isoform X12
- UniProtKB: I3LYK3 (UniProtKB/TrEMBL),   I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140622   ⟸   XM_040284688
- Peptide Label: isoform X10
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140621   ⟸   XM_040284687
- Peptide Label: isoform X10
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140612   ⟸   XM_040284678
- Peptide Label: isoform X2
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140624   ⟸   XM_040284690
- Peptide Label: isoform X10
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140619   ⟸   XM_040284685
- Peptide Label: isoform X8
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040140618   ⟸   XM_040284684
- Peptide Label: isoform X7
- UniProtKB: I3NDI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000001280   ⟸   ENSSTOT00000001427
RefSeq Acc Id: ENSSTOP00000022428   ⟸   ENSSTOT00000028593
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000001423 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000001427.3 UniProtKB/TrEMBL
  ENSSTOT00000028593.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PKHA4/5/6/7_PH UniProtKB/TrEMBL
NCBI Gene Plekha7 ENTREZGENE
PANTHER PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt I3LYK3 ENTREZGENE, UniProtKB/TrEMBL
  I3NDI1 ENTREZGENE, UniProtKB/TrEMBL