Rad23b (RAD23 nucleotide excision repair protein B) - Rat Genome Database

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Pathways
Gene: Rad23b (RAD23 nucleotide excision repair protein B) Rattus norvegicus
Analyze
Symbol: Rad23b
Name: RAD23 nucleotide excision repair protein B (Ensembl:RAD23 homolog B, nucleotide excision repair protein)
RGD ID: 1562958
Description: Predicted to enable several functions, including DNA damage sensor activity; proteasome binding activity; and ubiquitin binding activity. Involved in embryonic organ development. Predicted to be located in cytoplasm and nucleus. Predicted to be part of XPC complex. Predicted to be active in cytosol and nucleoplasm. Orthologous to human RAD23B (RAD23 homolog B, nucleotide excision repair protein); PARTICIPATES IN nucleotide excision repair pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-pilocarpine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC298012; MGC112630; RAD23 homolog B; RAD23 homolog B (S. cerevisiae); RAD23 homolog B, nucleotide excision repair protein; RAD23b homolog; RAD23b homolog (S. cerevisiae); similar to MHR23B; UV excision repair protein RAD23 homolog B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8574,885,518 - 74,923,621 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl574,885,516 - 74,962,426 (+)EnsemblGRCr8
mRatBN7.2570,090,232 - 70,128,340 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl570,090,232 - 70,128,319 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx571,970,372 - 72,008,648 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0573,797,196 - 73,835,069 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0573,769,324 - 73,807,197 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0572,103,704 - 72,141,701 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl572,103,704 - 72,141,700 (+)Ensemblrn6Rnor6.0
Rnor_5.0576,267,574 - 76,305,117 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4573,256,542 - 73,294,296 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera568,949,047 - 68,987,190 (+)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium acetate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorophyllin  (ISO)
choline  (ISO)
cisplatin  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
depsipeptide  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
isobutanol  (ISO)
isoniazide  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (EXP)
LY294002  (ISO)
MeIQx  (ISO)
menadione  (ISO)
Mesaconitine  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (EXP)
nitrates  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
p-menthan-3-ol  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
PhIP  (ISO)
pinosylvin  (ISO)
pirinixic acid  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium chloride  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trans-pinosylvin  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vitamin E  (ISO)
wortmannin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. TFIIH: when transcription met DNA repair. Compe E and Egly JM, Nat Rev Mol Cell Biol. 2012 May 10;13(6):343-54. doi: 10.1038/nrm3350.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Nucleotide excision repair gene expression in the rat conceptus during organogenesis. Vinson RK and Hales BF, Mutat Res. 2001 Jul 12;486(2):113-23.
Additional References at PubMed
PMID:8168482   PMID:9734359   PMID:11279143   PMID:11809813   PMID:12815074   PMID:19182904   PMID:19435460   PMID:19941824   PMID:22431748   PMID:22871113   PMID:25901318   PMID:29581031  


Genomics

Comparative Map Data
Rad23b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8574,885,518 - 74,923,621 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl574,885,516 - 74,962,426 (+)EnsemblGRCr8
mRatBN7.2570,090,232 - 70,128,340 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl570,090,232 - 70,128,319 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx571,970,372 - 72,008,648 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0573,797,196 - 73,835,069 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0573,769,324 - 73,807,197 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0572,103,704 - 72,141,701 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl572,103,704 - 72,141,700 (+)Ensemblrn6Rnor6.0
Rnor_5.0576,267,574 - 76,305,117 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4573,256,542 - 73,294,296 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera568,949,047 - 68,987,190 (+)NCBICelera
Cytogenetic Map5q24NCBI
RAD23B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389107,283,279 - 107,332,194 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9107,283,137 - 107,332,192 (+)Ensemblhg38GRCh38
GRCh379110,045,560 - 110,094,475 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369109,085,365 - 109,134,291 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349107,125,098 - 107,174,025NCBI
Celera980,547,624 - 80,596,476 (+)NCBICelera
Cytogenetic Map9q31.2NCBI
HuRef979,647,342 - 79,696,523 (+)NCBIHuRef
CHM1_19110,192,246 - 110,241,111 (+)NCBICHM1_1
T2T-CHM13v2.09119,455,054 - 119,503,938 (+)NCBIT2T-CHM13v2.0
Rad23b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39455,350,042 - 55,392,237 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl455,350,043 - 55,392,237 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38455,350,042 - 55,392,237 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl455,350,043 - 55,392,237 (+)Ensemblmm10GRCm38
MGSCv37455,362,914 - 55,405,109 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36455,371,157 - 55,412,312 (+)NCBIMGSCv36mm8
Celera455,261,308 - 55,305,783 (+)NCBICelera
Cytogenetic Map4B3NCBI
cM Map429.7NCBI
Rad23b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541919,429,970 - 19,460,796 (-)Ensembl
ChiLan1.0NW_00495541919,428,415 - 19,473,181 (-)NCBIChiLan1.0ChiLan1.0
RAD23B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21132,077,773 - 32,125,225 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1932,078,843 - 32,130,941 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0978,433,461 - 78,482,157 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19106,622,383 - 106,670,314 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9106,622,377 - 106,670,317 (+)EnsemblpanPan2panpan1.1
RAD23B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11162,732,989 - 62,778,957 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1162,732,984 - 62,775,978 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1161,131,232 - 61,177,125 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01163,874,392 - 63,920,316 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1163,874,474 - 63,918,434 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11162,397,151 - 62,443,059 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01162,407,466 - 62,453,391 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01163,109,368 - 63,155,283 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rad23b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947178,001,694 - 178,041,910 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365595,226,223 - 5,264,491 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365595,224,679 - 5,264,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD23B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1248,448,265 - 248,493,647 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11248,447,991 - 248,493,651 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21278,901,650 - 278,947,022 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAD23B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11232,203,501 - 32,250,555 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1232,204,893 - 32,250,570 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603510,428,681 - 10,476,086 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rad23b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247584,167,215 - 4,211,487 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247584,168,341 - 4,211,893 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rad23b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1196,138,665 - 96,176,842 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rad23b
375 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:244
Count of miRNA genes:149
Interacting mature miRNAs:202
Transcripts:ENSRNOT00000021629
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)573779642103472210Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 13 84 213 91 90 59 145 59 6 471 272 22 191 109 124 31 34 34

Sequence


Ensembl Acc Id: ENSRNOT00000021629   ⟹   ENSRNOP00000021629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl574,885,516 - 74,924,652 (+)Ensembl
mRatBN7.2 Ensembl570,090,232 - 70,128,319 (+)Ensembl
Rnor_6.0 Ensembl572,103,704 - 72,141,700 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118370   ⟹   ENSRNOP00000097319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl574,885,516 - 74,924,652 (+)Ensembl
mRatBN7.2 Ensembl570,090,232 - 70,128,319 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000142815   ⟹   ENSRNOP00000099817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl574,885,516 - 74,962,426 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000143851   ⟹   ENSRNOP00000108434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl574,885,516 - 74,959,964 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000150344   ⟹   ENSRNOP00000103316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl574,885,516 - 74,933,858 (+)Ensembl
RefSeq Acc Id: NM_001025275   ⟹   NP_001020446
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8574,885,518 - 74,923,621 (+)NCBI
mRatBN7.2570,090,232 - 70,128,340 (+)NCBI
Rnor_6.0572,103,704 - 72,141,701 (+)NCBI
Rnor_5.0576,267,574 - 76,305,117 (+)NCBI
RGSC_v3.4573,256,542 - 73,294,296 (+)RGD
Celera568,949,047 - 68,987,190 (+)RGD
Sequence:
RefSeq Acc Id: NP_001020446   ⟸   NM_001025275
- UniProtKB: Q5CZZ8 (UniProtKB/Swiss-Prot),   Q0D2G8 (UniProtKB/Swiss-Prot),   Q6IRD5 (UniProtKB/Swiss-Prot),   Q4KMA2 (UniProtKB/Swiss-Prot),   A6KDQ3 (UniProtKB/TrEMBL),   A0A8I6AUT2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021629   ⟸   ENSRNOT00000021629
Ensembl Acc Id: ENSRNOP00000097319   ⟸   ENSRNOT00000118370
Ensembl Acc Id: ENSRNOP00000108434   ⟸   ENSRNOT00000143851
Ensembl Acc Id: ENSRNOP00000103316   ⟸   ENSRNOT00000150344
Ensembl Acc Id: ENSRNOP00000099817   ⟸   ENSRNOT00000142815
Protein Domains
STI1   UBA   Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KMA2-F1-model_v2 AlphaFold Q4KMA2 1-415 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693749
Promoter ID:EPDNEW_R4274
Type:multiple initiation site
Name:Rad23b_1
Description:RAD23 homolog B, nucleotide excision repair protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0572,103,710 - 72,103,770EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562958 AgrOrtholog
BioCyc Gene G2FUF-41244 BioCyc
Ensembl Genes ENSRNOG00000016137 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021629 ENTREZGENE
  ENSRNOT00000021629.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.540 UniProtKB/Swiss-Prot
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7099379 IMAGE-MGC_LOAD
  IMAGE:7190031 IMAGE-MGC_LOAD
  IMAGE:7312455 IMAGE-MGC_LOAD
  IMAGE:7445676 IMAGE-MGC_LOAD
InterPro Rad23 UniProtKB/Swiss-Prot
  RAD23A/B_UBA1 UniProtKB/Swiss-Prot
  STI1_HS-bd UniProtKB/Swiss-Prot
  UBA UniProtKB/Swiss-Prot
  UBA-like_sf UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
  Ubiquitin_dom UniProtKB/Swiss-Prot
  XPC-bd UniProtKB/Swiss-Prot
  XPC-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:298012 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105481 IMAGE-MGC_LOAD
  MGC:112630 IMAGE-MGC_LOAD
  MGC:124964 IMAGE-MGC_LOAD
  MGC:91771 IMAGE-MGC_LOAD
NCBI Gene 298012 ENTREZGENE
PANTHER UV EXCISION REPAIR PROTEIN RAD23 UniProtKB/Swiss-Prot
  UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG B UniProtKB/Swiss-Prot
Pfam UBA UniProtKB/Swiss-Prot
  ubiquitin UniProtKB/Swiss-Prot
  XPC-binding UniProtKB/Swiss-Prot
PhenoGen Rad23b PhenoGen
PRINTS RAD23PROTEIN UniProtKB/Swiss-Prot
PROSITE UBA UniProtKB/Swiss-Prot
  UBIQUITIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016137 RatGTEx
SMART STI1 UniProtKB/Swiss-Prot
  UBA UniProtKB/Swiss-Prot
  UBQ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF101238 UniProtKB/Swiss-Prot
  SSF46934 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
UniProt A0A8I6AUT2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LD01_RAT UniProtKB/TrEMBL
  A0ABK0LDD2_RAT UniProtKB/TrEMBL
  A0ABK0LRA1_RAT UniProtKB/TrEMBL
  A6KDQ3 ENTREZGENE, UniProtKB/TrEMBL
  A6KDQ4_RAT UniProtKB/TrEMBL
  A6KDQ6_RAT UniProtKB/TrEMBL
  Q0D2G8 ENTREZGENE
  Q4KMA2 ENTREZGENE
  Q5CZZ8 ENTREZGENE
  Q6IRD5 ENTREZGENE
  RD23B_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q0D2G8 UniProtKB/Swiss-Prot
  Q5CZZ8 UniProtKB/Swiss-Prot
  Q6IRD5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Rad23b  RAD23 nucleotide excision repair protein B  Rad23b  RAD23 homolog B, nucleotide excision repair protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-17 Rad23b  RAD23 homolog B, nucleotide excision repair protein  Rad23b  RAD23 homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Rad23b  RAD23 homolog B (S. cerevisiae)  Rad23b  RAD23b homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Rad23b  RAD23b homolog (S. cerevisiae)  LOC298012  similar to MHR23B  Symbol and Name updated 1299863 APPROVED
2006-02-09 LOC298012  similar to MHR23B      Symbol and Name status set to provisional 70820 PROVISIONAL