Eci2 (enoyl-CoA delta isomerase 2) - Rat Genome Database

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Gene: Eci2 (enoyl-CoA delta isomerase 2) Rattus norvegicus
Analyze
Symbol: Eci2
Name: enoyl-CoA delta isomerase 2
RGD ID: 1359427
Description: Enables delta(3)-delta(2)-enoyl-CoA isomerase activity. Involved in fatty acid beta-oxidation. Located in peroxisome. Orthologous to human ECI2 (enoyl-CoA delta isomerase 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: D3,D2-enoyl-CoA isomerase; delta(3),delta(2)-enoyl-CoA isomerase; dodecenoyl-CoA isomerase; enoyl-CoA delta isomerase 2, mitochondrial; enoyl-Coenzyme A delta isomerase 2; MGC94706; Peci; peroxisomal 3,2-trans-enoyl-CoA isomerase; peroxisomal D3,D2-enoyl-CoA isomerase; peroxisomal delta3, delta2-enoyl-Coenzyme A isomerase; similar to Peci protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81730,056,274 - 30,092,169 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1730,076,524 - 30,092,161 (+)EnsemblGRCr8
mRatBN7.21729,850,884 - 29,886,781 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1729,870,391 - 29,886,781 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1729,697,249 - 29,713,626 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01731,300,993 - 31,317,370 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01729,692,972 - 29,709,349 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01730,556,926 - 30,573,324 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1730,556,884 - 30,639,040 (+)Ensemblrn6Rnor6.0
Rnor_5.01732,456,608 - 32,473,006 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41736,198,752 - 36,215,199 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1729,440,358 - 29,456,756 (+)NCBICelera
RGSC_v3.11736,201,592 - 36,218,037 (+)NCBI
Cytogenetic Map17p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
arsenite(3-)  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bezafibrate  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (EXP)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
fenamidone  (ISO)
fenofibrate  (EXP)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
glafenine  (EXP)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP)
indometacin  (EXP)
ivermectin  (ISO)
L-ethionine  (EXP)
leflunomide  (EXP)
Muraglitazar  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
nobiletin  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sulindac  (EXP)
sunitinib  (ISO)
Tesaglitazar  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
Torularhodin  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (EXP)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrion  (IBA,IEA,ISO)
peroxisomal matrix  (IBA,IEA,ISO)
peroxisome  (IDA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Characterization of PECI, a novel monofunctional Delta(3), Delta(2)-enoyl-CoA isomerase of mammalian peroxisomes. Geisbrecht BV, etal., J Biol Chem 1999 Jul 30;274(31):21797-803.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
6. Functional characterization of Delta3,Delta2-enoyl-CoA isomerases from rat liver. Zhang D, etal., J Biol Chem. 2002 Mar 15;277(11):9127-32. Epub 2002 Jan 7.
Additional References at PubMed
PMID:14561759   PMID:18614015   PMID:19946888   PMID:20178365   PMID:24344334   PMID:25515061  


Genomics

Comparative Map Data
Eci2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81730,056,274 - 30,092,169 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1730,076,524 - 30,092,161 (+)EnsemblGRCr8
mRatBN7.21729,850,884 - 29,886,781 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1729,870,391 - 29,886,781 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1729,697,249 - 29,713,626 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01731,300,993 - 31,317,370 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01729,692,972 - 29,709,349 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01730,556,926 - 30,573,324 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1730,556,884 - 30,639,040 (+)Ensemblrn6Rnor6.0
Rnor_5.01732,456,608 - 32,473,006 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41736,198,752 - 36,215,199 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1729,440,358 - 29,456,756 (+)NCBICelera
RGSC_v3.11736,201,592 - 36,218,037 (+)NCBI
Cytogenetic Map17p12NCBI
ECI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3864,115,706 - 4,135,575 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl64,115,685 - 4,135,597 (-)Ensemblhg38GRCh38
GRCh3764,115,940 - 4,135,809 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3664,060,926 - 4,080,830 (-)NCBIBuild 36Build 36hg18NCBI36
Celera65,344,491 - 5,364,393 (-)NCBICelera
Cytogenetic Map6p25.2NCBI
HuRef63,992,233 - 4,012,127 (-)NCBIHuRef
CHM1_164,118,762 - 4,138,665 (-)NCBICHM1_1
T2T-CHM13v2.063,984,995 - 4,004,863 (-)NCBIT2T-CHM13v2.0
Eci2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391335,161,731 - 35,211,098 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1335,161,731 - 35,211,079 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381334,977,748 - 35,027,115 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1334,977,748 - 35,027,096 (-)Ensemblmm10GRCm38
MGSCv371335,069,617 - 35,086,013 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361334,985,214 - 35,001,581 (-)NCBIMGSCv36mm8
Celera1336,108,118 - 36,124,460 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1314.23NCBI
Eci2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554659,296,973 - 9,314,942 (+)Ensembl
ChiLan1.0NW_0049554659,297,794 - 9,314,409 (+)NCBIChiLan1.0ChiLan1.0
ECI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2518,742,235 - 18,762,166 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1614,746,238 - 14,766,104 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v063,948,748 - 3,968,634 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.164,137,612 - 4,157,426 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl64,137,353 - 4,157,538 (-)EnsemblpanPan2panpan1.1
ECI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1354,349,075 - 4,368,219 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl354,342,214 - 4,366,331 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha354,358,525 - 4,379,268 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0354,411,021 - 4,431,664 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl354,402,727 - 4,431,646 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1354,286,023 - 4,306,883 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0354,307,504 - 4,328,446 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0355,642,089 - 5,662,568 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Eci2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494620,037,629 - 20,055,228 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365348,306,636 - 8,324,942 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365348,306,669 - 8,323,454 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl72,421,054 - 2,446,319 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.172,426,126 - 2,446,172 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.272,506,958 - 2,523,596 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ECI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11768,034,906 - 68,054,825 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1768,034,939 - 68,054,657 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660444,071,650 - 4,091,575 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eci2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475621,005,073 - 21,021,457 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475621,003,768 - 21,021,461 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Eci2
322 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:154
Count of miRNA genes:117
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000022022
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17926675540968173Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)173006647275066472Rat
8552966Pigfal18Plasma insulin-like growth factor 1 level QTL 188.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)171286094257860942Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172266079955604694Rat
9589151Insul30Insulin level QTL 308.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)171286094257860942Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172149899450592236Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172328632264246472Rat
9589057Scfw6Subcutaneous fat weight QTL 68.620.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)171286094257860942Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)172652205171522051Rat
9590154Scort9Serum corticosterone level QTL 923.570.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)171286094257860942Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172201970567019705Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
9590088Insglur7Insulin/glucose ratio QTL 720.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)171286094257860942Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)171060469455604694Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171553702560531414Rat
7411666Foco31Food consumption QTL 3111.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)171286094257860942Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172385892668858926Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17857434232199534Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172385892668858926Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172723344565155015Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172723344572233445Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172385892668858926Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172385892668858926Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172385892668858926Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat

Markers in Region
BG376613  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21729,869,972 - 29,870,153 (+)MAPPERmRatBN7.2
Rnor_6.01730,556,521 - 30,556,701NCBIRnor6.0
Rnor_5.01732,456,203 - 32,456,383UniSTSRnor5.0
RGSC_v3.41736,198,347 - 36,198,527UniSTSRGSC3.4
Celera1729,439,953 - 29,440,133UniSTS
RH 3.4 Map17326.51UniSTS
Cytogenetic Map17p12UniSTS
RH134397  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21729,886,423 - 29,886,620 (+)MAPPERmRatBN7.2
Rnor_6.01730,572,972 - 30,573,168NCBIRnor6.0
Rnor_5.01732,472,654 - 32,472,850UniSTSRnor5.0
RGSC_v3.41736,214,847 - 36,215,043UniSTSRGSC3.4
Celera1729,456,404 - 29,456,600UniSTS
RH 3.4 Map17371.6UniSTS
Cytogenetic Map17p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 51 67 138 95 11 50 36 32 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000022022   ⟹   ENSRNOP00000022022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1730,076,524 - 30,092,161 (+)Ensembl
mRatBN7.2 Ensembl1729,870,391 - 29,886,781 (+)Ensembl
Rnor_6.0 Ensembl1730,556,926 - 30,573,310 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000048923   ⟹   ENSRNOP00000050206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1730,130,787 - 30,149,137 (+)Ensembl
mRatBN7.2 Ensembl1729,921,977 - 29,943,860 (+)Ensembl
Rnor_6.0 Ensembl1730,617,382 - 30,639,040 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080929   ⟹   ENSRNOP00000072135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1730,128,588 - 30,149,137 (+)Ensembl
mRatBN7.2 Ensembl1729,923,200 - 29,943,862 (+)Ensembl
Rnor_6.0 Ensembl1730,556,884 - 30,638,954 (+)Ensembl
RefSeq Acc Id: NM_001006966   ⟹   NP_001006967
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,075,766 - 30,092,164 (+)NCBI
mRatBN7.21729,870,378 - 29,886,776 (+)NCBI
Rnor_6.01730,556,926 - 30,573,324 (+)NCBI
Rnor_5.01732,456,608 - 32,473,006 (+)NCBI
RGSC_v3.41736,198,752 - 36,215,199 (+)RGD
Celera1729,440,358 - 29,456,756 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095482   ⟹   XP_038951410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,056,274 - 30,092,169 (+)NCBI
mRatBN7.21729,850,884 - 29,886,781 (+)NCBI
RefSeq Acc Id: XM_039095483   ⟹   XP_038951411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,075,735 - 30,092,169 (+)NCBI
mRatBN7.21729,870,330 - 29,886,781 (+)NCBI
RefSeq Acc Id: XM_039095484   ⟹   XP_038951412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,075,271 - 30,092,169 (+)NCBI
mRatBN7.21729,870,016 - 29,886,781 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001006967 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951410 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951411 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951412 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83764 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022022
GenBank Protein Q5XIC0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001006967   ⟸   NM_001006966
- Peptide Label: precursor
- UniProtKB: Q5XIC0 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022022   ⟸   ENSRNOT00000022022
Ensembl Acc Id: ENSRNOP00000072135   ⟸   ENSRNOT00000080929
Ensembl Acc Id: ENSRNOP00000050206   ⟸   ENSRNOT00000048923
RefSeq Acc Id: XP_038951410   ⟸   XM_039095482
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QBE2 (UniProtKB/TrEMBL),   A6J7E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951412   ⟸   XM_039095484
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QBE2 (UniProtKB/TrEMBL),   A6J7E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951411   ⟸   XM_039095483
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QBE2 (UniProtKB/TrEMBL),   A6J7E6 (UniProtKB/TrEMBL)
Protein Domains
ACB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIC0-F1-model_v2 AlphaFold Q5XIC0 1-391 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700405
Promoter ID:EPDNEW_R10928
Type:multiple initiation site
Name:Eci2_1
Description:enoyl-CoA delta isomerase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10929  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01730,556,939 - 30,556,999EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359427 AgrOrtholog
BioCyc Gene G2FUF-9621 BioCyc
BioCyc Pathway FAO-PWY [fatty acid beta-oxidation I (generic)] BioCyc
  PWY-5137 [fatty acid beta-oxidation III (unsaturated, odd number)] BioCyc
BioCyc Pathway Image FAO-PWY BioCyc
  PWY-5137 BioCyc
Ensembl Genes ENSRNOG00000029549 Ensembl
  ENSRNOG00000066714 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000022022 ENTREZGENE
Gene3D-CATH 1.10.12.10 UniProtKB/Swiss-Prot
  1.20.80.10 UniProtKB/Swiss-Prot
  2-enoyl-CoA Hydratase, Chain A, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7193133 IMAGE-MGC_LOAD
InterPro Acyl-CoA-binding_prot_CS UniProtKB/Swiss-Prot
  Acyl-CoA-binding_protein UniProtKB/Swiss-Prot
  Acyl-CoA-binding_sf UniProtKB/Swiss-Prot
  ClpP/crotonase-like_dom_sf UniProtKB/Swiss-Prot
  ECH/Chromodomain_protein UniProtKB/Swiss-Prot
  Enoyl-CoA_hydra/iso UniProtKB/Swiss-Prot
  Enoyl-CoA_hydra_C UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
KEGG Report rno:291075 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94706 IMAGE-MGC_LOAD
NCBI Gene 291075 ENTREZGENE
PANTHER ENOYL-COA DELTA ISOMERASE 2 UniProtKB/Swiss-Prot
  PTHR43684 UniProtKB/Swiss-Prot
Pfam ACBP UniProtKB/Swiss-Prot
  ECH_1 UniProtKB/Swiss-Prot
PhenoGen Eci2 PhenoGen
PRINTS ACOABINDINGP UniProtKB/Swiss-Prot
PROSITE ACB_1 UniProtKB/Swiss-Prot
  ACB_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000029549 RatGTEx
  ENSRNOG00000066714 RatGTEx
Superfamily-SCOP SSF47027 UniProtKB/Swiss-Prot
  SSF52096 UniProtKB/Swiss-Prot
UniProt A0A8L2QBE2 ENTREZGENE, UniProtKB/TrEMBL
  A6J7E6 ENTREZGENE, UniProtKB/TrEMBL
  ECI2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-03 Eci2  enoyl-CoA delta isomerase 2  Eci2  enoyl-Coenzyme A delta isomerase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-03-17 Eci2  enoyl-Coenzyme A delta isomerase 2  Peci  peroxisomal D3,D2-enoyl-CoA isomerase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-11 Peci  peroxisomal D3,D2-enoyl-CoA isomerase  Peci  peroxisomal delta3, delta2-enoyl-Coenzyme A isomerase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Peci  peroxisomal delta3, delta2-enoyl-Coenzyme A isomerase      Name updated 1299863 APPROVED
2005-07-29 Peci  similar to Peci protein      Symbol and Name status set to provisional 70820 PROVISIONAL