Clec4e (C-type lectin domain family 4, member E) - Rat Genome Database

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Gene: Clec4e (C-type lectin domain family 4, member E) Rattus norvegicus
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Symbol: Clec4e
Name: C-type lectin domain family 4, member E
RGD ID: 1359298
Description: Predicted to enable several functions, including calcium ion binding activity; glycolipid binding activity; and pattern recognition receptor activity. Predicted to be involved in antifungal innate immune response; pattern recognition receptor signaling pathway; and positive regulation of cytokine production. Predicted to act upstream of or within Fc-gamma receptor signaling pathway; T cell differentiation involved in immune response; and defense response to bacterium. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane and phagocytic vesicle membrane. Orthologous to human CLEC4E (C-type lectin domain family 4 member E); PARTICIPATES IN tuberculosis pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C-type lectin domain family 4 member E; C-type lectin superfamily member 9; Clecsf9; immunoreceptor; macrophage-inducible C-type lectin; mincle
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84158,292,624 - 158,298,607 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4158,293,311 - 158,298,467 (-)EnsemblGRCr8
mRatBN7.24156,606,927 - 156,612,911 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4156,607,614 - 156,612,767 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4162,859,832 - 162,864,988 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04158,642,716 - 158,647,872 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04157,288,124 - 157,293,280 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04156,271,087 - 156,276,243 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4156,270,920 - 156,276,304 (-)Ensemblrn6Rnor6.0
Rnor_5.04223,287,319 - 223,293,143 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44159,901,953 - 159,907,090 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4145,397,723 - 145,402,880 (-)NCBICelera
RGSC_v3.14160,146,888 - 160,152,042 (-)NCBI
Cytogenetic Map4q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mincle, the receptor for mycobacterial cord factor, forms a functional receptor complex with MCL and FcεRI-γ. Lobato-Pascual A, etal., Eur J Immunol. 2013 Dec;43(12):3167-74. doi: 10.1002/eji.201343752. Epub 2013 Aug 26.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Mincle is an ITAM-coupled activating receptor that senses damaged cells. Yamasaki S, etal., Nat Immunol. 2008 Oct;9(10):1179-88. doi: 10.1038/ni.1651. Epub 2008 Sep 7.
8. C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia. Yamasaki S, etal., Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1897-902. doi: 10.1073/pnas.0805177106. Epub 2009 Jan 26.
Additional References at PubMed
PMID:15368084   PMID:23602766   PMID:24101491   PMID:26138128   PMID:28393919   PMID:30353660   PMID:31725411  


Genomics

Comparative Map Data
Clec4e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84158,292,624 - 158,298,607 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4158,293,311 - 158,298,467 (-)EnsemblGRCr8
mRatBN7.24156,606,927 - 156,612,911 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4156,607,614 - 156,612,767 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4162,859,832 - 162,864,988 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04158,642,716 - 158,647,872 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04157,288,124 - 157,293,280 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04156,271,087 - 156,276,243 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4156,270,920 - 156,276,304 (-)Ensemblrn6Rnor6.0
Rnor_5.04223,287,319 - 223,293,143 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44159,901,953 - 159,907,090 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4145,397,723 - 145,402,880 (-)NCBICelera
RGSC_v3.14160,146,888 - 160,152,042 (-)NCBI
Cytogenetic Map4q42NCBI
CLEC4E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,533,275 - 8,540,905 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,533,305 - 8,540,905 (-)Ensemblhg38GRCh38
GRCh37128,685,871 - 8,693,501 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,577,168 - 8,584,825 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34128,577,167 - 8,584,811NCBI
Celera1210,221,897 - 10,229,555 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef128,468,250 - 8,475,908 (-)NCBIHuRef
CHM1_1128,654,869 - 8,662,532 (-)NCBICHM1_1
T2T-CHM13v2.0128,516,734 - 8,524,370 (-)NCBIT2T-CHM13v2.0
Clec4e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396123,258,748 - 123,266,830 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6123,258,748 - 123,266,829 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386123,281,789 - 123,289,871 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6123,281,789 - 123,289,870 (-)Ensemblmm10GRCm38
MGSCv376123,231,807 - 123,239,889 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366123,247,408 - 123,255,490 (-)NCBIMGSCv36mm8
Celera6125,079,435 - 125,087,544 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map658.35NCBI
Clec4e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554135,256,440 - 5,262,938 (+)Ensembl
ChiLan1.0NW_0049554135,256,523 - 5,261,385 (+)NCBIChiLan1.0ChiLan1.0
CLEC4E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21014,057,708 - 14,070,479 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11214,054,468 - 14,067,239 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,620,618 - 8,627,610 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,835,598 - 8,842,081 (-)NCBIPanPan1.1PanPan1.1panPan2
LOC611538
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12737,561,445 - 37,568,652 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2737,563,038 - 37,568,463 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha279,047,754 - 9,054,953 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02737,914,984 - 37,922,184 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2737,904,114 - 37,922,172 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12737,789,556 - 37,796,752 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02737,831,158 - 37,838,354 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,534,492 - 8,541,692 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Clec4e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494599,900,137 - 99,906,784 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936858316,954 - 321,668 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936858316,954 - 321,668 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLEC4E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1563,219,229 - 63,228,566 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CLEC4E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,315,888 - 8,322,240 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,316,049 - 8,321,274 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666089414,308 - 420,182 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clec4e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248604,108,640 - 4,113,839 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248604,108,782 - 4,113,693 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Clec4e
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1624,065,388 - 24,071,072 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Clec4e
60 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:16
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000013562
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4150095743159267220Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4148834094168870974Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 43 87 79 78 47 92 47 6 302 168 11 65 63 63 31 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000078725   ⟹   ENSRNOP00000073160
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4158,293,311 - 158,298,467 (-)Ensembl
mRatBN7.2 Ensembl4156,607,614 - 156,612,767 (-)Ensembl
Rnor_6.0 Ensembl4156,270,920 - 156,276,304 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112159   ⟹   ENSRNOP00000096103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4158,293,311 - 158,298,467 (-)Ensembl
mRatBN7.2 Ensembl4156,607,614 - 156,612,767 (-)Ensembl
RefSeq Acc Id: NM_001005897   ⟹   NP_001005897
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84158,293,311 - 158,298,467 (-)NCBI
mRatBN7.24156,607,614 - 156,612,770 (-)NCBI
Rnor_6.04156,271,087 - 156,276,243 (-)NCBI
Rnor_5.04223,287,319 - 223,293,143 (-)NCBI
RGSC_v3.44159,901,953 - 159,907,090 (-)RGD
Celera4145,397,723 - 145,402,880 (-)RGD
Sequence:
RefSeq Acc Id: XM_039108009   ⟹   XP_038963937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84158,292,624 - 158,298,607 (-)NCBI
mRatBN7.24156,606,927 - 156,612,911 (-)NCBI
RefSeq Acc Id: XM_039108010   ⟹   XP_038963938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84158,292,624 - 158,297,682 (-)NCBI
mRatBN7.24156,606,927 - 156,611,987 (-)NCBI
RefSeq Acc Id: XR_005503275
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84158,292,624 - 158,298,606 (-)NCBI
mRatBN7.24156,606,927 - 156,612,911 (-)NCBI
RefSeq Acc Id: NP_001005897   ⟸   NM_001005897
- UniProtKB: G3V7B4 (UniProtKB/TrEMBL),   A6ILH3 (UniProtKB/TrEMBL),   Q2TUL7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073160   ⟸   ENSRNOT00000078725
RefSeq Acc Id: XP_038963937   ⟸   XM_039108009
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AQ60 (UniProtKB/TrEMBL),   Q2TUL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963938   ⟸   XM_039108010
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000096103   ⟸   ENSRNOT00000112159
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q67EQ1-F1-model_v2 AlphaFold Q67EQ1 1-215 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359298 AgrOrtholog
BioCyc Gene G2FUF-43125 BioCyc
Ensembl Genes ENSRNOG00000061394 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000078725 ENTREZGENE
  ENSRNOT00000112159 ENTREZGENE
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot
InterPro C-type_lectin-like UniProtKB/Swiss-Prot
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot
  C-type_lectin/snaclec_domain UniProtKB/Swiss-Prot
  C-type_lectin_CS UniProtKB/Swiss-Prot
  CD209-like_CTLD UniProtKB/Swiss-Prot
  CTDL_fold UniProtKB/Swiss-Prot
KEGG Report rno:450223 UniProtKB/Swiss-Prot
NCBI Gene 450223 ENTREZGENE
PANTHER MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED UniProtKB/Swiss-Prot
Pfam Lectin_C UniProtKB/Swiss-Prot
PhenoGen Clec4e PhenoGen
PROSITE C_TYPE_LECTIN_1 UniProtKB/Swiss-Prot
  C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000061394 RatGTEx
SMART CLECT UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot
UniProt A0A8I6AQ60 ENTREZGENE, UniProtKB/TrEMBL
  A6ILH3 ENTREZGENE, UniProtKB/TrEMBL
  CLC4E_RAT UniProtKB/Swiss-Prot
  G3V7B4 ENTREZGENE, UniProtKB/TrEMBL
  Q2TUL7 ENTREZGENE, UniProtKB/TrEMBL
  Q67EQ1 ENTREZGENE
UniProt Secondary Q56TZ4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-06-08 Clec4e  C-type lectin domain family 4, member E  Clec4e  C-type lectin domain family 4, member e  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Clec4e  C-type lectin domain family 4, member e  Clecsf9  macrophage-inducible C-type lectin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 Clecsf9  macrophage-inducible C-type lectin      Symbol and Name status set to provisional 70820 PROVISIONAL