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| # | Reference Title | Reference Citation |
| 1. | Hypothyroidism in the adult rat causes brain region-specific biochemical dysfunction. | Ahmed MT, etal., J Endocrinol. 1993 Aug;138(2):299-305. |
| 2. | Late onset MLD with normal nerve conduction associated with two novel missense mutations in the ASA gene. | Gallo S, etal., J Neurol Neurosurg Psychiatry 2004 Apr;75(4):655-7. |
| 3. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 4. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
| 5. | Ethanol decreases rat hepatic arylsulfatase A activity levels. | Jean S, etal., Alcohol Clin Exp Res. 2006 Nov;30(11):1950-5. |
| 6. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 7. | Rat sperm AS-A: subcellular localization in testis and epididymis and surface distribution in epididymal sperm. | Ngernsoungnern A, etal., Cell Tissue Res. 2004 Nov;318(2):353-63. Epub 2004 Sep 30. |
| 8. | The effect of pH on the kinetics of arylsulphatases A and B. | O'Fagain C, etal., Biochem J. 1983 Sep 1;213(3):603-7. |
| 9. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
| 10. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 11. | SMPDB Annotation Import Pipeline | Pipeline to import SMPDB annotations from SMPDB into RGD |
| 12. | GOA pipeline | RGD automated data pipeline |
| 13. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 14. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 15. | Autophagy-related changes of arylsulphatases A and B in rat liver lysosomes. | Sanghavi P and Koenig H, Biochem J. 1976 Jun 1;155(3):725-8. |
| 16. | ASA E382K disrupts a potential exonic splicing enhancer and causes exon skipping, but missense mutations in ASA are not associated with ESEs. | Shotelersuk V, etal., Int J Mol Med 2004 Oct;14(4):683-9. |
| 17. | Studies on urinary arylsulphatase activity in vitamin A deficient rats. | Srinivas L and Rao PB, Int J Vitam Nutr Res. 1976;46(1):3-10. |
| 18. | Role of sperm surface arylsulfatase A in mouse sperm-zona pellucida binding. | Tantibhedhyangkul J, etal., Biol Reprod 2002 Jul;67(1):212-9. |
| 19. | Developmental profiles of arylsulfatases A and B in rat cerebral cortex and spinal cord. | van der Pal RH, etal., Biochim Biophys Acta. 1991 Feb 5;1081(3):315-20. |
| 20. | Inability of thiol compounds to restore CNS arylsulfatases inhibited by methyl mercury. | Vinay SD and Sood PP, Pharmacol Toxicol. 1991 Jul;69(1):71-4. |
| 21. | Purification of rat liver arylsulfatase A and its microheterogeneity assayed by crossed affinity-immunoelectrophoresis. | Wojczyk B, etal., Acta Biochim Pol. 1992;39(4):355-67. |
| 22. | Enzymic changes in the cervix of the rat and hamster during the oestrous cycle and the effect of steroids. | Zachariah E and Moudgal NR, J Endocrinol. 1977 Feb;72(2):153-61. |
| PMID:12477932 | PMID:12888274 | PMID:15962010 | PMID:16174644 | PMID:23376485 | PMID:23533145 | PMID:24006456 |
| Arsa (Rattus norvegicus - Norway rat) |
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| ARSA (Homo sapiens - human) |
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| Arsa (Mus musculus - house mouse) |
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| Arsa (Chinchilla lanigera - long-tailed chinchilla) |
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| ARSA (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ARSA (Canis lupus familiaris - dog) |
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| Arsa (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ARSA (Sus scrofa - pig) |
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| ARSA (Chlorocebus sabaeus - green monkey) |
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| Arsa (Heterocephalus glaber - naked mole-rat) |
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| Arsa (Rattus rattus - black rat) |
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.
Variants in Arsa
15 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| BI277783 |
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| DLAT |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 67 | 164 | 91 | 90 | 59 | 92 | 59 | 6 | 356 | 192 | 11 | 143 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_001034933 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_017594886 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AC125982 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| BC105852 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BN000735 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474027 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ212178 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000017783 ⟹ ENSRNOP00000017782 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001034933 ⟹ NP_001030105 | ||||||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| Protein RefSeqs | NP_001030105 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAI05853 | (Get FASTA) | NCBI Sequence Viewer |
| CAI84981 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL76575 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL76576 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000017782 | ||
| ENSRNOP00000017782.4 |
| RefSeq Acc Id: | NP_001030105 ⟸ NM_001034933 |
| - Peptide Label: | precursor |
| - UniProtKB: | Q32KK2 (UniProtKB/TrEMBL), F7FF93 (UniProtKB/TrEMBL), Q3KR80 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000017782 ⟸ ENSRNOT00000017783 |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-Q32KK2-F1-model_v2 | AlphaFold | Q32KK2 | 1-507 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| RGD ID: | 13695590 | ||||||||
| Promoter ID: | EPDNEW_R6115 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Arsa_1 | ||||||||
| Description: | arylsulfatase A | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
|
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1310381 | AgrOrtholog |
| BioCyc Gene | G2FUF-32432 | BioCyc |
| Ensembl Genes | ENSRNOG00000012953 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000017783 | ENTREZGENE |
| ENSRNOT00000017783.8 | UniProtKB/TrEMBL | |
| Gene3D-CATH | 3.30.1120.10 | UniProtKB/TrEMBL |
| 3.40.720.10 | UniProtKB/TrEMBL | |
| IMAGE_CLONE | IMAGE:7452956 | IMAGE-MGC_LOAD |
| InterPro | Alkaline_phosphatase_core | UniProtKB/TrEMBL |
| Sulfatase | UniProtKB/TrEMBL | |
| Sulfatase | UniProtKB/TrEMBL | |
| Sulfatase_CS | UniProtKB/TrEMBL | |
| KEGG Report | rno:315222 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:125207 | IMAGE-MGC_LOAD |
| NCBI Gene | 315222 | ENTREZGENE |
| PANTHER | ARYLSULFATASE A | UniProtKB/TrEMBL |
| ARYLSULFATASE FAMILY MEMBER | UniProtKB/TrEMBL | |
| Pfam | Sulfatase | UniProtKB/TrEMBL |
| Sulfatase_C | UniProtKB/TrEMBL | |
| PhenoGen | Arsa | PhenoGen |
| PROSITE | SULFATASE_1 | UniProtKB/TrEMBL |
| SULFATASE_2 | UniProtKB/TrEMBL | |
| RatGTEx | ENSRNOG00000012953 | RatGTEx |
| Superfamily-SCOP | Alkaline_phosphatase_core | UniProtKB/TrEMBL |
| UniProt | A6K7N3_RAT | UniProtKB/TrEMBL |
| F7FF93 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q32KK2 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q3KR80 | ENTREZGENE, UniProtKB/TrEMBL |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2005-12-06 | Arsa | arylsulfatase A | Arsa_predicted | arylsulfatase A (predicted) | Symbol and Name updated | 1559027 | APPROVED |
| 2005-01-12 | Arsa_predicted | arylsulfatase A (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |