Arsa (arylsulfatase A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Arsa (arylsulfatase A) Mus musculus
Analyze
Symbol: Arsa
Name: arylsulfatase A
RGD ID: 1321257
MGI Page MGI
Description: Predicted to enable arylsulfatase activity and calcium ion binding activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in plasma membrane. Is expressed in brain and genitourinary system. Used to study metachromatic leukodystrophy. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy. Orthologous to human ARSA (arylsulfatase A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A; As; As-2; AS-A; As2; ASA; AW212749; C230037L18Rik; cerebroside-sulfatase; TISP73
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,356,679 - 89,361,627 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1589,356,679 - 89,361,628 (-)EnsemblGRCm39 Ensembl
GRCm381589,472,476 - 89,477,424 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,472,476 - 89,477,425 (-)EnsemblGRCm38mm10GRCm38
MGSCv371589,302,907 - 89,307,855 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361589,300,261 - 89,316,421 (-)NCBIMGSCv36mm8
Celera1591,601,657 - 91,606,605 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axon morphology  (IAGP)
abnormal brain internal capsule morphology  (IAGP)
abnormal brain white matter morphology  (IAGP)
abnormal cerebellar molecular layer  (IAGP)
abnormal epididymis morphology  (IAGP)
abnormal eye morphology  (IAGP)
abnormal gait  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal lysosome morphology  (IAGP)
abnormal male germ cell morphology  (IAGP)
abnormal microglial cell morphology  (IAGP)
abnormal myelination  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal passive avoidance behavior  (IAGP)
abnormal Purkinje cell morphology  (IAGP)
abnormal Schwann cell morphology  (IAGP)
abnormal seminiferous tubule epithelium morphology  (IAGP)
abnormal Sertoli cell morphology  (IAGP)
abnormal spatial learning  (IAGP)
abnormal sperm head morphology  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal testis morphology  (IAGP)
abnormal vestibular ganglion morphology  (IAGP)
astrocytosis  (IAGP)
ataxia  (IAGP)
cochlear ganglion degeneration  (IAGP)
coiled sperm flagellum  (IAGP)
deafness  (IAGP)
decreased Sertoli cell phagocytosis  (IAGP)
decreased testis weight  (IAGP)
demyelination  (IAGP)
hyperactivity  (IAGP)
impaired balance  (IAGP)
impaired binding of sperm to zona pellucida  (IAGP)
impaired coordination  (IAGP)
impaired fertilization  (IAGP)
impaired swimming  (IAGP)
increased male germ cell apoptosis  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
oligozoospermia  (IAGP)
Purkinje cell degeneration  (IAGP)
reduced male fertility  (IAGP)
short stride length  (IAGP)
teratozoospermia  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Hypothyroidism in the adult rat causes brain region-specific biochemical dysfunction. Ahmed MT, etal., J Endocrinol. 1993 Aug;138(2):299-305.
2. Late onset MLD with normal nerve conduction associated with two novel missense mutations in the ASA gene. Gallo S, etal., J Neurol Neurosurg Psychiatry 2004 Apr;75(4):655-7.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. ASA E382K disrupts a potential exonic splicing enhancer and causes exon skipping, but missense mutations in ASA are not associated with ESEs. Shotelersuk V, etal., Int J Mol Med 2004 Oct;14(4):683-9.
14. Role of sperm surface arylsulfatase A in mouse sperm-zona pellucida binding. Tantibhedhyangkul J, etal., Biol Reprod 2002 Jul;67(1):212-9.
Additional References at PubMed
PMID:1572648   PMID:6118238   PMID:7910580   PMID:8962139   PMID:9728336   PMID:10349636   PMID:10505624   PMID:10575108   PMID:10822308   PMID:10922068   PMID:11042159   PMID:11076861  
PMID:11430883   PMID:11685544   PMID:11919180   PMID:12021068   PMID:12074561   PMID:12477932   PMID:12773421   PMID:14681479   PMID:15188402   PMID:15193296   PMID:15733089   PMID:15772092  
PMID:15962010   PMID:16141072   PMID:16141073   PMID:16554462   PMID:16602821   PMID:16630546   PMID:17715338   PMID:17728461   PMID:17845130   PMID:17883393   PMID:18287559   PMID:18336930  
PMID:18420734   PMID:19224915   PMID:19637231   PMID:19860853   PMID:20297902   PMID:20503373   PMID:21267068   PMID:21451524   PMID:21459117   PMID:21490328   PMID:21873635   PMID:21965315  
PMID:22388935   PMID:22685254   PMID:22923692   PMID:23883774   PMID:24006456   PMID:25605750   PMID:25632048   PMID:25896249   PMID:31312839   PMID:32325033   PMID:34199863   PMID:35273160  


Genomics

Comparative Map Data
Arsa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,356,679 - 89,361,627 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1589,356,679 - 89,361,628 (-)EnsemblGRCm39 Ensembl
GRCm381589,472,476 - 89,477,424 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,472,476 - 89,477,425 (-)EnsemblGRCm38mm10GRCm38
MGSCv371589,302,907 - 89,307,855 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361589,300,261 - 89,316,421 (-)NCBIMGSCv36mm8
Celera1591,601,657 - 91,606,605 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.94NCBI
ARSA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382250,622,754 - 50,628,152 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2250,622,754 - 50,628,173 (-)EnsemblGRCh38hg38GRCh38
GRCh372251,061,182 - 51,066,580 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,410,315 - 49,413,473 (-)NCBINCBI36Build 36hg18NCBI36
Build 342249,353,599 - 49,356,720NCBI
Celera2234,939,475 - 34,942,633 (-)NCBICelera
Cytogenetic Map22q13.33ENTREZGENE
HuRef2233,951,640 - 33,957,003 (-)NCBIHuRef
CHM1_12251,019,964 - 51,025,351 (-)NCBICHM1_1
T2T-CHM13v2.02251,133,297 - 51,138,663 (-)NCBIT2T-CHM13v2.0
Arsa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,422,971 - 122,426,971 (-)NCBIGRCr8
mRatBN7.27120,542,788 - 120,547,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,543,362 - 120,548,783 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7122,296,387 - 122,298,913 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,522,533 - 124,525,059 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,484,772 - 124,487,298 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,446,644 - 130,452,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,446,668 - 130,451,283 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07130,131,465 - 130,137,453 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,790,208 - 127,792,734 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17127,824,434 - 127,826,966 (-)NCBI
Celera7117,017,039 - 117,019,565 (-)NCBICelera
Cytogenetic Map7q34NCBI
Arsa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541333,623,525 - 33,629,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541333,624,460 - 33,629,491 (-)NCBIChiLan1.0ChiLan1.0
ARSA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22360,542,613 - 60,545,784 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12263,231,615 - 63,236,318 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02230,868,812 - 30,871,970 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12249,978,955 - 49,982,108 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2249,978,955 - 49,982,099 (-)Ensemblpanpan1.1panPan2
ARSA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11016,691,927 - 16,694,346 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1016,691,758 - 16,695,398 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1016,669,563 - 16,671,982 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01017,418,229 - 17,420,648 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1017,417,717 - 17,423,153 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11017,142,642 - 17,145,061 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01017,465,701 - 17,468,120 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01017,597,813 - 17,600,232 (+)NCBIUU_Cfam_GSD_1.0
Arsa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945187,281 - 205,493 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936629187,275 - 191,008 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936629187,281 - 205,493 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARSA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5107,149 - 111,518 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15107,103 - 110,330 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap5p15-p11NCBI
ARSA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11933,102,803 - 33,105,958 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1933,100,117 - 33,105,926 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366654618,495 - 21,647 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arsa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624752149,187 - 153,746 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624752149,248 - 153,625 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arsa
134 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:860
Count of miRNA genes:495
Interacting mature miRNAs:598
Transcripts:ENSMUST00000023292, ENSMUST00000165199, ENSMUST00000168052, ENSMUST00000168270
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
1558845Alprf_malcohol preference (mouse)Not determined158734927190274568Mouse
12738413Lfibq10_mliver fibrosis QTL 10 (mouse)158784208589927286Mouse

Markers in Region
AW212749  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381589,472,637 - 89,472,754UniSTSGRCm38
MGSCv371589,303,068 - 89,303,185UniSTSGRCm37
Celera1591,601,818 - 91,601,935UniSTS
Cytogenetic Map15EUniSTS
Whitehead/MRC_RH15819.97UniSTS
Arsa  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381589,474,976 - 89,475,561UniSTSGRCm38
MGSCv371589,305,407 - 89,305,992UniSTSGRCm37
Celera1591,604,157 - 91,604,742UniSTS
Cytogenetic Map15EUniSTS
cM Map15 UniSTS
DLAT  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381589,474,619 - 89,474,824UniSTSGRCm38
MGSCv371589,305,050 - 89,305,255UniSTSGRCm37
Celera1591,603,800 - 91,604,005UniSTS
Cytogenetic Map15EUniSTS
Arsa  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15EUniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000023292
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1589,356,731 - 89,360,316 (-)Ensembl
GRCm38.p6 Ensembl1589,472,528 - 89,476,113 (-)Ensembl
RefSeq Acc Id: ENSMUST00000165199   ⟹   ENSMUSP00000127646
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1589,356,679 - 89,361,628 (-)Ensembl
GRCm38.p6 Ensembl1589,472,476 - 89,477,425 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168052
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1589,360,434 - 89,361,614 (-)Ensembl
GRCm38.p6 Ensembl1589,476,231 - 89,477,411 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168270   ⟹   ENSMUSP00000130574
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1589,357,443 - 89,358,474 (-)Ensembl
GRCm38.p6 Ensembl1589,473,240 - 89,474,271 (-)Ensembl
RefSeq Acc Id: NM_009713   ⟹   NP_033843
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391589,356,679 - 89,361,627 (-)NCBI
GRCm381589,472,476 - 89,477,424 (-)ENTREZGENE
MGSCv371589,302,907 - 89,307,855 (-)RGD
Celera1591,601,657 - 91,606,605 (-)RGD
cM Map15 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033843   ⟸   NM_009713
- Peptide Label: precursor
- UniProtKB: Q9DC66 (UniProtKB/Swiss-Prot),   P50428 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000127646   ⟸   ENSMUST00000165199
RefSeq Acc Id: ENSMUSP00000130574   ⟸   ENSMUST00000168270
Protein Domains
N-sulphoglucosamine sulphohydrolase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P50428-F1-model_v2 AlphaFold P50428 1-506 view protein structure

Promoters
RGD ID:6847164
Promoter ID:MM_ACW:19061
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:ARSA.CSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361589,304,226 - 89,304,726 (-)MPROMDB
RGD ID:6847167
Promoter ID:MM_ACW:19062
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ARSA.DSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361589,305,126 - 89,305,626 (-)MPROMDB
RGD ID:6825785
Promoter ID:MM_KWN:19435
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK082325_C230037L18RIK,   ENSMUST00000023292,   NM_009713
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361589,306,421 - 89,306,921 (-)MPROMDB
RGD ID:8684744
Promoter ID:EPDNEW_M20403
Type:initiation region
Name:Arsa_2
Description:Mus musculus arylsulfatase A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20405  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381589,476,102 - 89,476,162EPDNEW
RGD ID:8684748
Promoter ID:EPDNEW_M20405
Type:initiation region
Name:Arsa_1
Description:Mus musculus arylsulfatase A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20403  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381589,477,406 - 89,477,466EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88077 AgrOrtholog
Ensembl Genes ENSMUSG00000022620 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000165199 ENTREZGENE
  ENSMUST00000165199.8 UniProtKB/Swiss-Prot
  ENSMUST00000168270.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1120.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.720.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Alkaline_phosphatase_core_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SGSH_C UniProtKB/TrEMBL
  Sulfatase_CS UniProtKB/Swiss-Prot
  Sulfatase_N UniProtKB/Swiss-Prot
KEGG Report mmu:11883 UniProtKB/Swiss-Prot
MGD MGI:88077 ENTREZGENE
NCBI Gene 11883 ENTREZGENE
PANTHER ARYLSULFATASE A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARYLSULFATASE FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SGSH_C UniProtKB/TrEMBL
  Sulfatase UniProtKB/Swiss-Prot
  Sulfatase_C UniProtKB/Swiss-Prot
PhenoGen Arsa PhenoGen
PROSITE SULFATASE_1 UniProtKB/Swiss-Prot
  SULFATASE_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53649 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ARSA_MOUSE UniProtKB/Swiss-Prot
  F6QGM0_MOUSE UniProtKB/TrEMBL
  P50428 ENTREZGENE
  Q8K4U2_MOUSE UniProtKB/TrEMBL
  Q9DC66 ENTREZGENE
UniProt Secondary Q9DC66 UniProtKB/Swiss-Prot