Aprt (adenine phosphoribosyl transferase) - Rat Genome Database

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Gene: Aprt (adenine phosphoribosyl transferase) Rattus norvegicus
Analyze
Symbol: Aprt
Name: adenine phosphoribosyl transferase
RGD ID: 1307758
Description: Enables AMP binding activity. Involved in cellular response to insulin stimulus and lactation. Predicted to be active in cytosol. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in adenine phosphoribosyltransferase deficiency. Orthologous to human APRT (adenine phosphoribosyltransferase); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adenine phosphoribosyltransferase; LOC292072
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,534,737 - 67,537,027 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21950,626,201 - 50,628,491 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,626,202 - 50,628,431 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1957,421,206 - 57,423,174 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,101,358 - 58,103,326 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,319,830 - 60,321,798 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,387,288 - 55,389,256 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,387,288 - 55,389,256 (-)Ensemblrn6Rnor6.0
Rnor_5.01966,095,804 - 66,097,772 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41952,854,657 - 52,856,625 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1949,865,842 - 49,867,810 (-)NCBICelera
RGSC_v3.11952,859,538 - 52,861,506 (-)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
Bufotalin  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
dibenzofurans  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
doxorubicin  (EXP,ISO)
epoxiconazole  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
GSK-J4  (ISO)
GW 4064  (ISO)
inulin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP,ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nimesulide  (EXP)
ochratoxin A  (ISO)
ozone  (ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
PhIP  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)
zidovudine  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Enzymes of the pathway of purine synthesis in the rat mammary gland. Changes in the lactation cycle and the effects of diabetes. Beardsley S, etal., Biochem J. 1988 Mar 1;250(2):395-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Purification of adenine phosphoribosyltransferase by affinity chromatography. Hershey HV and Taylor MW, Prep Biochem. 1978;8(6):453-62.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Enzymic capacities of purine de Novo and salvage pathways for nucleotide synthesis in normal and neoplastic tissues. Natsumeda Y, etal., Cancer Res. 1984 Jun;44(6):2475-9.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. Identification of two novel mutations in adenine phosphoribosyltransferase gene in patients with 2,8-dihydroxyadenine urolithiasis. Taniguchi A, etal., Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1141-5.
15. Increased de novo purine synthesis by insulin through selective enzyme induction in primary cultured rat hepatocytes. Tsuchiya M, etal., Am J Physiol. 1990 May;258(5 Pt 1):C841-8.
Additional References at PubMed
PMID:198184   PMID:1235912   PMID:6307822   PMID:7323947   PMID:7444718   PMID:8112572   PMID:8485579   PMID:8643571   PMID:8864750   PMID:8894695   PMID:9218001   PMID:15196008  
PMID:19056867   PMID:20458337   PMID:23376485   PMID:23533145   PMID:24625528  


Genomics

Comparative Map Data
Aprt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,534,737 - 67,537,027 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21950,626,201 - 50,628,491 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,626,202 - 50,628,431 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1957,421,206 - 57,423,174 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,101,358 - 58,103,326 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,319,830 - 60,321,798 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,387,288 - 55,389,256 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,387,288 - 55,389,256 (-)Ensemblrn6Rnor6.0
Rnor_5.01966,095,804 - 66,097,772 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41952,854,657 - 52,856,625 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1949,865,842 - 49,867,810 (-)NCBICelera
RGSC_v3.11952,859,538 - 52,861,506 (-)NCBI
Cytogenetic Map19q12NCBI
APRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,809,339 - 88,811,928 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,809,339 - 88,811,963 (-)Ensemblhg38GRCh38
GRCh371688,875,747 - 88,878,336 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,403,378 - 87,405,843 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341687,403,379 - 87,405,879NCBI
Celera1673,944,514 - 73,946,979 (-)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,573,103 - 74,575,568 (-)NCBIHuRef
CHM1_11690,287,144 - 90,289,609 (-)NCBICHM1_1
T2T-CHM13v2.01694,879,859 - 94,882,448 (-)NCBIT2T-CHM13v2.0
Aprt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,301,376 - 123,303,646 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,301,374 - 123,303,648 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388122,574,637 - 122,576,907 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,574,635 - 122,576,909 (-)Ensemblmm10GRCm38
MGSCv378125,098,537 - 125,100,807 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368125,460,727 - 125,462,950 (-)NCBIMGSCv36mm8
Celera8126,804,235 - 126,806,505 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.91NCBI
Aprt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,687,938 - 2,690,906 (-)Ensembl
ChiLan1.0NW_0049555412,687,938 - 2,690,906 (-)NCBIChiLan1.0ChiLan1.0
APRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,582,498 - 98,585,192 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,494,670 - 104,497,177 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,522,628 - 69,525,138 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,179,020 - 89,181,505 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,179,020 - 89,181,504 (-)EnsemblpanPan2panpan1.1
APRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,563,154 - 64,565,537 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,563,192 - 64,565,445 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha564,574,619 - 64,577,004 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0564,783,377 - 64,785,760 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,783,416 - 64,785,668 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,809,556 - 64,811,939 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,641,062 - 64,643,445 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,047,101 - 65,049,491 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Aprt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,160,104 - 25,162,762 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641913,475 - 918,748 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936641913,674 - 916,312 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6890,831 - 893,276 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16890,272 - 893,278 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.261,090,009 - 1,092,413 (-)NCBISscrofa10.2Sscrofa10.2susScr3
APRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,196,858 - 74,199,789 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,194,013 - 74,199,891 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660471,479,268 - 1,482,118 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aprt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746805,758 - 807,963 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746805,742 - 807,963 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Aprt
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11742,203,352 - 42,205,626 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:42
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000064180
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
Aprt  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21950,626,747 - 50,627,000 (+)MAPPERmRatBN7.2
Rnor_6.01955,387,600 - 55,387,852NCBIRnor6.0
Rnor_5.01966,096,116 - 66,096,368UniSTSRnor5.0
RGSC_v3.41952,854,969 - 52,855,221UniSTSRGSC3.4
Celera1949,866,154 - 49,866,406UniSTS
Cytogenetic Map19q12UniSTS
RH127914  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81967,534,983 - 67,535,299 (+)Marker Load Pipeline
mRatBN7.21950,626,447 - 50,626,763 (+)MAPPERmRatBN7.2
Rnor_6.01955,387,300 - 55,387,615NCBIRnor6.0
Rnor_5.01966,095,816 - 66,096,131UniSTSRnor5.0
RGSC_v3.41952,854,669 - 52,854,984UniSTSRGSC3.4
Celera1949,865,854 - 49,866,169UniSTS
RH 3.4 Map19699.71UniSTS
Cytogenetic Map19q12UniSTS
RH94458  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21950,626,416 - 50,626,575 (+)MAPPERmRatBN7.2
Rnor_6.01955,387,269 - 55,387,427NCBIRnor6.0
Rnor_5.01966,095,785 - 66,095,943UniSTSRnor5.0
RGSC_v3.41952,854,638 - 52,854,796UniSTSRGSC3.4
Celera1949,865,823 - 49,865,981UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000064180   ⟹   ENSRNOP00000061449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1950,626,202 - 50,628,431 (-)Ensembl
Rnor_6.0 Ensembl1955,387,288 - 55,389,256 (-)Ensembl
RefSeq Acc Id: NM_001013061   ⟹   NP_001013079
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81967,534,737 - 67,537,027 (-)NCBI
mRatBN7.21950,626,201 - 50,628,491 (-)NCBI
Rnor_6.01955,387,288 - 55,389,256 (-)NCBI
Rnor_5.01966,095,804 - 66,097,772 (-)NCBI
RGSC_v3.41952,854,657 - 52,856,625 (-)RGD
Celera1949,865,842 - 49,867,810 (-)RGD
Sequence:
RefSeq Acc Id: NP_001013079   ⟸   NM_001013061
- UniProtKB: P36972 (UniProtKB/Swiss-Prot),   A0A8L2QU71 (UniProtKB/TrEMBL),   A6IZS8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061449   ⟸   ENSRNOT00000064180
Protein Domains
Phosphoribosyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P36972-F1-model_v2 AlphaFold P36972 1-180 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701212
Promoter ID:EPDNEW_R11735
Type:initiation region
Name:Aprt_1
Description:adenine phosphoribosyl transferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01955,389,287 - 55,389,347EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307758 AgrOrtholog
BioCyc Gene G2FUF-5381 BioCyc
BioCyc Pathway P121-PWY [adenine and adenosine salvage I] BioCyc
BioCyc Pathway Image P121-PWY BioCyc
Ensembl Genes ENSRNOG00000014405 Ensembl
Gene3D-CATH 3.40.50.2020 UniProtKB/Swiss-Prot
InterPro Ade_phspho_trans UniProtKB/Swiss-Prot
  PRibTrfase_dom UniProtKB/Swiss-Prot
  PRTase-like UniProtKB/Swiss-Prot
  UPRTase/APRTase UniProtKB/Swiss-Prot
KEGG Report rno:292072 UniProtKB/Swiss-Prot
NCBI Gene 292072 ENTREZGENE
PANTHER ADENINE PHOSPHORIBOSYLTRANSFERASE UniProtKB/Swiss-Prot
  ADENINE PHOSPHORIBOSYLTRANSFERASE UniProtKB/Swiss-Prot
Pfam Pribosyltran UniProtKB/Swiss-Prot
PhenoGen Aprt PhenoGen
PROSITE PUR_PYR_PR_TRANSFER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014405 RatGTEx
Superfamily-SCOP SSF53271 UniProtKB/Swiss-Prot
UniProt A0A8L2QU71 ENTREZGENE, UniProtKB/TrEMBL
  A6IZS8 ENTREZGENE, UniProtKB/TrEMBL
  APT_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Aprt  adenine phosphoribosyl transferase   Aprt_predicted  adenine phosphoribosyl transferase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Aprt_predicted  adenine phosphoribosyl transferase (predicted)      Symbol and Name status set to approved 70820 APPROVED