Map4k4 (mitogen-activated protein kinase kinase kinase kinase 4) - Rat Genome Database

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Gene: Map4k4 (mitogen-activated protein kinase kinase kinase kinase 4) Rattus norvegicus
Analyze
Symbol: Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
RGD ID: 1305322
Description: Predicted to enable ATP binding activity; kinase activity; and microtubule binding activity. Involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus and negative regulation of neuron projection regeneration. Predicted to be located in focal adhesion. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4); PARTICIPATES IN ceramide signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; tumor necrosis factor mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC301363
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8949,696,573 - 49,822,353 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl949,696,700 - 49,822,353 (+)EnsemblGRCr8
mRatBN7.2942,200,708 - 42,326,708 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx950,702,578 - 50,828,197 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0955,825,326 - 55,950,939 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0954,101,736 - 54,227,399 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0946,657,444 - 46,782,545 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl946,657,575 - 46,782,545 (+)Ensemblrn6Rnor6.0
Rnor_5.0946,342,983 - 46,469,618 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4939,087,924 - 39,213,053 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera939,949,780 - 40,073,740 (+)NCBICelera
RGSC_v3.1939,072,258 - 39,212,860 (+)NCBI
Cytogenetic Map9q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
aconitine  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (EXP)
bortezomib  (ISO)
bucladesine  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cerium trichloride  (ISO)
chloroprene  (EXP)
choline  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gallic acid  (ISO)
gamma-hexachlorocyclohexane  (EXP)
hexadecanoic acid  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
inulin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nitrates  (EXP)
ochratoxin A  (ISO)
okadaic acid  (ISO)
oleic acid  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sertraline  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfates  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (EXP,ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)
focal adhesion  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion. Bouzakri K, etal., J Biol Chem. 2009 Oct 9;284(41):27892-8. doi: 10.1074/jbc.M109.048058. Epub 2009 Aug 18.
2. Silencing CDC25A inhibits the proliferation of liver cancer cells by downregulating IL‑6 in vitro and in vivo. Chen S, etal., Int J Mol Med. 2020 Mar;45(3):743-752. doi: 10.3892/ijmm.2020.4461. Epub 2020 Jan 9.
3. Role of microRNA-141 in colorectal cancer with lymph node metastasis. Feng L, etal., Exp Ther Med. 2016 Nov;12(5):3405-3410. doi: 10.3892/etm.2016.3751. Epub 2016 Sep 27.
4. MAP4K4 promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma. Feng XJ, etal., Tumour Biol. 2016 Aug;37(8):11457-67. doi: 10.1007/s13277-016-5022-1. Epub 2016 Mar 24.
5. MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance. Gao X, etal., Mol Oncol. 2017 Jun;11(6):628-639. doi: 10.1002/1878-0261.12055. Epub 2017 May 2.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Construction and validation of a novel prognostic signature of microRNAs in lung adenocarcinoma. Li W, etal., PeerJ. 2021 Jan 8;9:e10470. doi: 10.7717/peerj.10470. eCollection 2021.
9. RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell. Lin JC, etal., Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):259-272. doi: 10.1016/j.bbamcr.2017.11.005. Epub 2017 Nov 11.
10. ShRNA-targeted MAP4K4 inhibits hepatocellular carcinoma growth. Liu AW, etal., Clin Cancer Res. 2011 Feb 15;17(4):710-20. doi: 10.1158/1078-0432.CCR-10-0331. Epub 2010 Dec 30.
11. Silencing of MAP4K4 by short hairpin RNA suppresses proliferation, induces G1 cell cycle arrest and induces apoptosis in gastric cancer cells. Liu YF, etal., Mol Med Rep. 2016 Jan;13(1):41-8. doi: 10.3892/mmr.2015.4510. Epub 2015 Nov 6.
12. Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen. Loh SH, etal., Cell Death Differ. 2008 Feb;15(2):283-98. Epub 2007 Nov 16.
13. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
16. GOA pipeline RGD automated data pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Comprehensive gene review and curation RGD comprehensive gene curation
20. MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway. Wang B, etal., Cell Cycle. 2015;14(7):1046-58. doi: 10.1080/15384101.2015.1007767.
Additional References at PubMed
PMID:9135144   PMID:9890973   PMID:14966141   PMID:22797597   PMID:23207904   PMID:24163766   PMID:25490267   PMID:25601402   PMID:25931508   PMID:26296893   PMID:35303564  


Genomics

Comparative Map Data
Map4k4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8949,696,573 - 49,822,353 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl949,696,700 - 49,822,353 (+)EnsemblGRCr8
mRatBN7.2942,200,708 - 42,326,708 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx950,702,578 - 50,828,197 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0955,825,326 - 55,950,939 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0954,101,736 - 54,227,399 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0946,657,444 - 46,782,545 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl946,657,575 - 46,782,545 (+)Ensemblrn6Rnor6.0
Rnor_5.0946,342,983 - 46,469,618 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4939,087,924 - 39,213,053 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera939,949,780 - 40,073,740 (+)NCBICelera
RGSC_v3.1939,072,258 - 39,212,860 (+)NCBI
Cytogenetic Map9q22NCBI
MAP4K4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382101,697,707 - 101,894,690 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2101,696,850 - 101,894,690 (+)Ensemblhg38GRCh38
GRCh372102,314,169 - 102,511,152 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362101,680,920 - 101,877,584 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342101,773,005 - 101,969,669NCBI
Celera296,515,852 - 96,712,368 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef296,077,883 - 96,275,019 (+)NCBIHuRef
CHM1_12102,318,538 - 102,515,492 (+)NCBICHM1_1
T2T-CHM13v2.02102,156,317 - 102,352,940 (+)NCBIT2T-CHM13v2.0
Map4k4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39139,939,806 - 40,065,470 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl139,940,073 - 40,065,470 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38139,900,902 - 40,026,310 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl139,900,913 - 40,026,310 (+)Ensemblmm10GRCm38
MGSCv37139,957,758 - 40,083,155 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36139,845,776 - 39,969,471 (+)NCBIMGSCv36mm8
Celera139,697,172 - 39,822,126 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map118.53NCBI
Map4k4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554707,333,351 - 7,470,751 (+)Ensembl
ChiLan1.0NW_0049554707,334,050 - 7,470,751 (+)NCBIChiLan1.0ChiLan1.0
MAP4K4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,337,096 - 26,530,653 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A26,336,669 - 26,533,414 (-)NCBINHGRI_mPanPan1
PanPan1.12A102,752,617 - 102,945,263 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A102,750,221 - 102,945,263 (+)EnsemblpanPan2panpan1.1
MAP4K4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11041,088,020 - 41,276,801 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1041,089,371 - 41,276,891 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1041,011,441 - 41,202,508 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01041,953,205 - 42,144,746 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1041,955,875 - 42,144,609 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11041,668,761 - 41,859,816 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01041,948,929 - 42,139,431 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01042,140,514 - 42,331,820 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Map4k4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629290,518,662 - 90,617,516 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936713435,238 - 612,835 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936713515,388 - 616,024 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAP4K4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl352,484,274 - 52,649,410 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1352,483,028 - 52,649,480 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2355,031,486 - 55,196,190 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAP4K4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1145,391,416 - 5,579,163 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl145,391,449 - 5,583,916 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041173,068,911 - 173,261,800 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Map4k4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247496,332,534 - 6,495,942 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247496,332,686 - 6,495,942 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Map4k4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14116,159,452 - 116,284,969 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Map4k4
1400 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:555
Count of miRNA genes:264
Interacting mature miRNAs:321
Transcripts:ENSRNOT00000019180
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)93145606157460683Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
AU045934  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8949,820,691 - 49,820,817 (+)Marker Load Pipeline
mRatBN7.2942,325,036 - 42,325,161 (+)MAPPERmRatBN7.2
Rnor_6.0946,780,884 - 46,781,008NCBIRnor6.0
Rnor_5.0946,466,256 - 46,466,380UniSTSRnor5.0
RGSC_v3.4939,211,392 - 39,211,516UniSTSRGSC3.4
Celera940,072,079 - 40,072,203UniSTS
Cytogenetic Map9q21UniSTS
RH129992  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,199,641 - 42,199,859 (+)MAPPERmRatBN7.2
Rnor_6.0946,655,944 - 46,656,161NCBIRnor6.0
Rnor_5.0946,341,490 - 46,341,707UniSTSRnor5.0
RGSC_v3.4939,085,946 - 39,086,163UniSTSRGSC3.4
Celera939,947,777 - 39,947,994UniSTS
RH 3.4 Map9393.09UniSTS
Cytogenetic Map9q21UniSTS
RH132131  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,300,637 - 42,300,823 (+)MAPPERmRatBN7.2
Rnor_6.0946,756,485 - 46,756,670NCBIRnor6.0
Rnor_5.0946,441,857 - 46,442,042UniSTSRnor5.0
RGSC_v3.4939,186,974 - 39,187,159UniSTSRGSC3.4
Celera940,047,603 - 40,047,788UniSTS
RH 3.4 Map9389.5UniSTS
Cytogenetic Map9q21UniSTS
AI454038  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,318,214 - 42,318,401 (+)MAPPERmRatBN7.2
Rnor_6.0946,774,062 - 46,774,248NCBIRnor6.0
Rnor_5.0946,459,434 - 46,459,620UniSTSRnor5.0
RGSC_v3.4939,204,570 - 39,204,756UniSTSRGSC3.4
Celera940,065,257 - 40,065,443UniSTS
RH 3.4 Map9389.5UniSTS
Cytogenetic Map9q21UniSTS
AW433645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,326,341 - 42,326,547 (+)MAPPERmRatBN7.2
Rnor_6.0946,782,189 - 46,782,394NCBIRnor6.0
Rnor_5.0946,467,561 - 46,467,766UniSTSRnor5.0
RGSC_v3.4939,212,697 - 39,212,902UniSTSRGSC3.4
Celera940,073,384 - 40,073,589UniSTS
RH 3.4 Map9389.5UniSTS
Cytogenetic Map9q21UniSTS
BG371733  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,308,967 - 42,309,063 (+)MAPPERmRatBN7.2
Rnor_6.0946,764,815 - 46,764,910NCBIRnor6.0
Rnor_5.0946,450,187 - 46,450,282UniSTSRnor5.0
RGSC_v3.4939,195,304 - 39,195,399UniSTSRGSC3.4
Celera940,055,933 - 40,056,028UniSTS
RH 3.4 Map10681.5UniSTS
Cytogenetic Map9q21UniSTS
BE119253  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,300,268 - 42,300,435 (+)MAPPERmRatBN7.2
Rnor_6.0946,756,116 - 46,756,282NCBIRnor6.0
Rnor_5.0946,441,488 - 46,441,654UniSTSRnor5.0
RGSC_v3.4939,186,605 - 39,186,771UniSTSRGSC3.4
Celera940,047,234 - 40,047,400UniSTS
RH 3.4 Map9393.9UniSTS
Cytogenetic Map9q21UniSTS
UniSTS:234115  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,325,036 - 42,325,132 (+)MAPPERmRatBN7.2
Rnor_6.0946,780,884 - 46,780,979NCBIRnor6.0
Rnor_5.0946,466,256 - 46,466,351UniSTSRnor5.0
RGSC_v3.4939,211,392 - 39,211,487UniSTSRGSC3.4
Celera940,072,079 - 40,072,174UniSTS
Cytogenetic Map9q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM217582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000019180   ⟹   ENSRNOP00000019180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl949,696,700 - 49,822,353 (+)Ensembl
mRatBN7.2 Ensembl942,273,275 - 42,326,698 (+)Ensembl
Rnor_6.0 Ensembl946,657,922 - 46,782,545 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083322   ⟹   ENSRNOP00000074373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl949,696,700 - 49,822,353 (+)Ensembl
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)Ensembl
Rnor_6.0 Ensembl946,657,575 - 46,781,136 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102137   ⟹   ENSRNOP00000092452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102257   ⟹   ENSRNOP00000097771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl949,696,700 - 49,822,353 (+)Ensembl
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105968   ⟹   ENSRNOP00000078532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111572   ⟹   ENSRNOP00000085187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl949,696,700 - 49,822,353 (+)Ensembl
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115451   ⟹   ENSRNOP00000078890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl949,696,700 - 49,822,353 (+)Ensembl
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115768   ⟹   ENSRNOP00000092349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl949,696,700 - 49,822,353 (+)Ensembl
mRatBN7.2 Ensembl942,200,278 - 42,326,698 (+)Ensembl
RefSeq Acc Id: NM_001106904   ⟹   NP_001100374
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,700 - 49,822,353 (+)NCBI
mRatBN7.2942,201,039 - 42,326,698 (+)NCBI
Rnor_6.0946,657,922 - 46,782,545 (+)NCBI
Rnor_5.0946,342,983 - 46,469,618 (+)NCBI
RGSC_v3.4939,087,924 - 39,213,053 (+)RGD
Celera939,949,780 - 40,073,740 (+)RGD
Sequence:
RefSeq Acc Id: NM_001401996   ⟹   NP_001388925
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,700 - 49,822,353 (+)NCBI
mRatBN7.2942,201,039 - 42,326,698 (+)NCBI
RefSeq Acc Id: XM_008767003   ⟹   XP_008765225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,575 - 49,822,353 (+)NCBI
mRatBN7.2942,200,715 - 42,326,708 (+)NCBI
Rnor_6.0946,657,445 - 46,782,545 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008767011   ⟹   XP_008765233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,586 - 49,822,353 (+)NCBI
mRatBN7.2942,200,915 - 42,326,699 (+)NCBI
Rnor_6.0946,657,447 - 46,782,545 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008767014   ⟹   XP_008765236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,584 - 49,822,353 (+)NCBI
mRatBN7.2942,200,914 - 42,326,699 (+)NCBI
Rnor_6.0946,657,447 - 46,782,545 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596342   ⟹   XP_017451831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,588 - 49,822,353 (+)NCBI
mRatBN7.2942,200,918 - 42,326,699 (+)NCBI
Rnor_6.0946,657,448 - 46,782,545 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596343   ⟹   XP_017451832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,581 - 49,822,353 (+)NCBI
mRatBN7.2942,200,909 - 42,326,699 (+)NCBI
Rnor_6.0946,657,446 - 46,782,545 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083226   ⟹   XP_038939154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,581 - 49,822,353 (+)NCBI
mRatBN7.2942,200,907 - 42,326,699 (+)NCBI
RefSeq Acc Id: XM_039083228   ⟹   XP_038939156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,582 - 49,822,353 (+)NCBI
mRatBN7.2942,200,909 - 42,326,699 (+)NCBI
RefSeq Acc Id: XM_039083231   ⟹   XP_038939159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,579 - 49,822,353 (+)NCBI
mRatBN7.2942,200,901 - 42,326,708 (+)NCBI
RefSeq Acc Id: XM_039083233   ⟹   XP_038939161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,585 - 49,822,353 (+)NCBI
mRatBN7.2942,200,914 - 42,326,699 (+)NCBI
RefSeq Acc Id: XM_039083234   ⟹   XP_038939162
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,584 - 49,822,353 (+)NCBI
mRatBN7.2942,200,912 - 42,326,699 (+)NCBI
RefSeq Acc Id: XM_039083235   ⟹   XP_038939163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,580 - 49,822,353 (+)NCBI
mRatBN7.2942,200,907 - 42,326,699 (+)NCBI
RefSeq Acc Id: XM_039083238   ⟹   XP_038939166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,583 - 49,822,353 (+)NCBI
mRatBN7.2942,200,911 - 42,326,708 (+)NCBI
RefSeq Acc Id: XM_039083239   ⟹   XP_038939167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,587 - 49,822,353 (+)NCBI
mRatBN7.2942,200,917 - 42,326,699 (+)NCBI
RefSeq Acc Id: XM_039083240   ⟹   XP_038939168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,577 - 49,822,353 (+)NCBI
mRatBN7.2942,200,899 - 42,326,708 (+)NCBI
RefSeq Acc Id: XM_039083242   ⟹   XP_038939170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,587 - 49,822,353 (+)NCBI
mRatBN7.2942,200,918 - 42,326,699 (+)NCBI
RefSeq Acc Id: XM_039083243   ⟹   XP_038939171
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,588 - 49,822,353 (+)NCBI
mRatBN7.2942,200,919 - 42,326,699 (+)NCBI
RefSeq Acc Id: XM_063266895   ⟹   XP_063122965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,574 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266896   ⟹   XP_063122966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,575 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266897   ⟹   XP_063122967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,579 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266898   ⟹   XP_063122968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,576 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266899   ⟹   XP_063122969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,574 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266900   ⟹   XP_063122970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,582 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266901   ⟹   XP_063122971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,578 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266902   ⟹   XP_063122972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,577 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266904   ⟹   XP_063122974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,573 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266905   ⟹   XP_063122975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,579 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266906   ⟹   XP_063122976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,577 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266907   ⟹   XP_063122977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,579 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266908   ⟹   XP_063122978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,577 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266909   ⟹   XP_063122979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,580 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266911   ⟹   XP_063122981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,576 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266912   ⟹   XP_063122982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,581 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266913   ⟹   XP_063122983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,583 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266914   ⟹   XP_063122984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,584 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266915   ⟹   XP_063122985
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,582 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266916   ⟹   XP_063122986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,589 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266917   ⟹   XP_063122987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,580 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266918   ⟹   XP_063122988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,584 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266919   ⟹   XP_063122989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,584 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266920   ⟹   XP_063122990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,585 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266921   ⟹   XP_063122991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,583 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266922   ⟹   XP_063122992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,582 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266923   ⟹   XP_063122993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,583 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266924   ⟹   XP_063122994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,581 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266925   ⟹   XP_063122995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,582 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266926   ⟹   XP_063122996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,584 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266927   ⟹   XP_063122997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,582 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266928   ⟹   XP_063122998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,588 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266929   ⟹   XP_063122999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,585 - 49,822,353 (+)NCBI
RefSeq Acc Id: XM_063266930   ⟹   XP_063123000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8949,696,580 - 49,822,353 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001100374 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388925 (Get FASTA)   NCBI Sequence Viewer  
  XP_008765225 (Get FASTA)   NCBI Sequence Viewer  
  XP_008765233 (Get FASTA)   NCBI Sequence Viewer  
  XP_008765236 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451831 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451832 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939154 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939156 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939159 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939161 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939162 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939163 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939166 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939167 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939168 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939170 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939171 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122965 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122966 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122967 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122968 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122969 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122970 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122971 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122972 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122974 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122975 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122976 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122977 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122978 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122979 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122981 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122982 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122983 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122984 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122985 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122986 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122987 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122988 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122989 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122990 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122991 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122992 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122993 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122994 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122995 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122996 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122997 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122998 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122999 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123000 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AIU47302 (Get FASTA)   NCBI Sequence Viewer  
  EDL99184 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019180
  ENSRNOP00000019180.8
  ENSRNOP00000074373.3
  ENSRNOP00000078890
  ENSRNOP00000078890.2
  ENSRNOP00000085187
  ENSRNOP00000085187.2
  ENSRNOP00000092349
  ENSRNOP00000092349.2
  ENSRNOP00000097771
  ENSRNOP00000097771.2
RefSeq Acc Id: NP_001100374   ⟸   NM_001106904
- Peptide Label: isoform 1
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765225   ⟸   XM_008767003
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765233   ⟸   XM_008767011
- Peptide Label: isoform X22
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765236   ⟸   XM_008767014
- Peptide Label: isoform X34
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451832   ⟸   XM_017596343
- Peptide Label: isoform X30
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451831   ⟸   XM_017596342
- Peptide Label: isoform X26
- UniProtKB: A0A8I6AT99 (UniProtKB/TrEMBL),   A0A8I5ZLV4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074373   ⟸   ENSRNOT00000083322
Ensembl Acc Id: ENSRNOP00000019180   ⟸   ENSRNOT00000019180
RefSeq Acc Id: XP_038939168   ⟸   XM_039083240
- Peptide Label: isoform X28
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939159   ⟸   XM_039083231
- Peptide Label: isoform X14
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939154   ⟸   XM_039083226
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K7W4 (UniProtKB/TrEMBL),   A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939163   ⟸   XM_039083235
- Peptide Label: isoform X20
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939156   ⟸   XM_039083228
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939166   ⟸   XM_039083238
- Peptide Label: isoform X24
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939162   ⟸   XM_039083234
- Peptide Label: isoform X19
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939161   ⟸   XM_039083233
- Peptide Label: isoform X18
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939167   ⟸   XM_039083239
- Peptide Label: isoform X27
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939170   ⟸   XM_039083242
- Peptide Label: isoform X35
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939171   ⟸   XM_039083243
- Peptide Label: isoform X36
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078532   ⟸   ENSRNOT00000105968
Ensembl Acc Id: ENSRNOP00000078890   ⟸   ENSRNOT00000115451
Ensembl Acc Id: ENSRNOP00000092452   ⟸   ENSRNOT00000102137
Ensembl Acc Id: ENSRNOP00000085187   ⟸   ENSRNOT00000111572
Ensembl Acc Id: ENSRNOP00000097771   ⟸   ENSRNOT00000102257
Ensembl Acc Id: ENSRNOP00000092349   ⟸   ENSRNOT00000115768
RefSeq Acc Id: NP_001388925   ⟸   NM_001401996
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL),   A0A8I6ADP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122974   ⟸   XM_063266904
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122965   ⟸   XM_063266895
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122969   ⟸   XM_063266899
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122966   ⟸   XM_063266896
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122981   ⟸   XM_063266911
- Peptide Label: isoform X23
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122968   ⟸   XM_063266898
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122976   ⟸   XM_063266906
- Peptide Label: isoform X15
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122972   ⟸   XM_063266902
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122978   ⟸   XM_063266908
- Peptide Label: isoform X17
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122971   ⟸   XM_063266901
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122975   ⟸   XM_063266905
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122967   ⟸   XM_063266897
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122977   ⟸   XM_063266907
- Peptide Label: isoform X16
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122987   ⟸   XM_063266917
- Peptide Label: isoform X37
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122979   ⟸   XM_063266909
- Peptide Label: isoform X21
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123000   ⟸   XM_063266930
- Peptide Label: isoform X50
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122994   ⟸   XM_063266924
- Peptide Label: isoform X44
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122982   ⟸   XM_063266912
- Peptide Label: isoform X25
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122995   ⟸   XM_063266925
- Peptide Label: isoform X45
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122992   ⟸   XM_063266922
- Peptide Label: isoform X42
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122970   ⟸   XM_063266900
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122997   ⟸   XM_063266927
- Peptide Label: isoform X47
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122985   ⟸   XM_063266915
- Peptide Label: isoform X32
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122983   ⟸   XM_063266913
- Peptide Label: isoform X29
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122991   ⟸   XM_063266921
- Peptide Label: isoform X41
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122993   ⟸   XM_063266923
- Peptide Label: isoform X43
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122988   ⟸   XM_063266918
- Peptide Label: isoform X38
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL),   A0A8I5ZYP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122989   ⟸   XM_063266919
- Peptide Label: isoform X39
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122996   ⟸   XM_063266926
- Peptide Label: isoform X46
- UniProtKB: A6INM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122984   ⟸   XM_063266914
- Peptide Label: isoform X31
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122990   ⟸   XM_063266920
- Peptide Label: isoform X40
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL),   A0A8I6AHN7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122999   ⟸   XM_063266929
- Peptide Label: isoform X49
- UniProtKB: A0A8I5ZLV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122998   ⟸   XM_063266928
- Peptide Label: isoform X48
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122986   ⟸   XM_063266916
- Peptide Label: isoform X33
- UniProtKB: A0A8I5ZL09 (UniProtKB/TrEMBL)
Protein Domains
CNH   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7W4-F1-model_v2 AlphaFold A0A0G2K7W4 1-1348 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305322 AgrOrtholog
BioCyc Gene G2FUF-27731 BioCyc
Ensembl Genes ENSRNOG00000014013 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019180 ENTREZGENE
  ENSRNOT00000019180.8 UniProtKB/TrEMBL
  ENSRNOT00000083322.3 UniProtKB/TrEMBL
  ENSRNOT00000102257 ENTREZGENE
  ENSRNOT00000102257.2 UniProtKB/TrEMBL
  ENSRNOT00000111572 ENTREZGENE
  ENSRNOT00000111572.2 UniProtKB/TrEMBL
  ENSRNOT00000115451 ENTREZGENE
  ENSRNOT00000115451.2 UniProtKB/TrEMBL
  ENSRNOT00000115768 ENTREZGENE
  ENSRNOT00000115768.2 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Citron UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  STE20_Ser-Thr_kinase UniProtKB/TrEMBL
KEGG Report rno:301363 UniProtKB/TrEMBL
NCBI Gene 301363 ENTREZGENE
PANTHER CNH DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MISSHAPEN LIKE KINASE 1 UniProtKB/TrEMBL
Pfam CNH UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PhenoGen Map4k4 PhenoGen
PROSITE CNH UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014013 RatGTEx
SMART CNH UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A097PIG6_RAT UniProtKB/TrEMBL
  A0A0G2K7W4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZL09 ENTREZGENE
  A0A8I5ZLV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYP2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADP3 ENTREZGENE
  A0A8I6AHN7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AT99 ENTREZGENE, UniProtKB/TrEMBL
  A6INM6 ENTREZGENE, UniProtKB/TrEMBL
  F1M754_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Map4k4  mitogen-activated protein kinase kinase kinase kinase 4   Map4k4_predicted  mitogen-activated protein kinase kinase kinase kinase 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Map4k4_predicted  mitogen-activated protein kinase kinase kinase kinase 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED