Gene: Zfp473 (zinc finger protein 473) Rattus norvegicus
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Symbol:
Zfp473
Name:
zinc finger protein 473
RGD ID:
1305084
Description:
Enables DNA-binding transcription factor binding activity. Involved in negative regulation of transcription initiation by RNA polymerase II. Predicted to be located in Cajal body. Predicted to be active in nucleus. Orthologous to human ZNF473 (zinc finger protein 473); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC292884; RGD1305084; similar to Zinc finger protein 184; zinc finger protein 473 homolog; Znf473
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 104,358,757 - 104,379,833 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 1 104,359,709 - 104,379,775 (-) Ensembl GRCr8 mRatBN7.2 1 95,222,683 - 95,243,328 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 95,223,433 - 95,243,325 (-) Ensembl mRatBN7.2 Rnor_6.0 1 100,736,319 - 100,755,498 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 100,736,243 - 100,746,021 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 1 101,800,924 - 101,820,140 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 1 95,211,692 - 95,221,283 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 1 89,486,059 - 89,505,241 (-) NCBI Celera RGSC_v3.1 1 95,266,640 - 95,299,394 (-) NCBI Cytogenetic Map 1 q22 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Zfp473 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of ZNF473 mRNA CTD PMID:22079256 Zfp473 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Zfp473 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zfp473 Rat 1,2-dichloroethane affects expression ISO Zfp473 (Mus musculus) 6480464 ethylene dichloride affects the expression of ZFP473 mRNA CTD PMID:28960355 Zfp473 Rat 1,2-dimethylhydrazine decreases expression ISO Zfp473 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of ZFP473 mRNA CTD PMID:22206623 Zfp473 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Zfp473 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zfp473 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Zfp473 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zfp473 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Zfp473 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ZFP473 mRNA CTD PMID:16962184|PMID:21570461 Zfp473 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ZFP473 mRNA CTD PMID:33387578 Zfp473 Rat 2,3,7,8-Tetrachlorodibenzofuran increases expression EXP 6480464 2,3,7,8-tetrachlorodibenzofuran results in increased expression of ZFP473 mRNA CTD PMID:32109520 Zfp473 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Zfp473 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zfp473 Rat 2-methylcholine affects expression ISO ZNF473 (Homo sapiens) 6480464 beta-methylcholine affects the expression of ZNF473 mRNA CTD PMID:21179406 Zfp473 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZFP473 mRNA CTD PMID:32119087 Zfp473 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... CTD PMID:28628672 Zfp473 Rat 4,4'-sulfonyldiphenol multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... CTD PMID:28628672 Zfp473 Rat 5-fluorouracil affects response to substance ISO ZNF473 (Homo sapiens) 6480464 ZNF473 protein affects the susceptibility to Fluorouracil CTD PMID:15331170 Zfp473 Rat 5-fluorouracil increases expression ISO ZNF473 (Homo sapiens) 6480464 Fluorouracil results in increased expression of ZNF473 mRNA CTD PMID:15331170 Zfp473 Rat acrylamide increases expression ISO ZNF473 (Homo sapiens) 6480464 Acrylamide results in increased expression of ZNF473 mRNA CTD PMID:32763439 Zfp473 Rat aflatoxin B1 increases expression ISO ZNF473 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of ZNF473 mRNA CTD PMID:22100608 Zfp473 Rat aflatoxin B1 increases methylation ISO ZNF473 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of ZNF473 gene CTD PMID:27153756 Zfp473 Rat all-trans-retinoic acid decreases expression ISO ZNF473 (Homo sapiens) 6480464 Tretinoin results in decreased expression of ZNF473 mRNA CTD PMID:23724009 Zfp473 Rat aristolochic acid A increases expression ISO ZNF473 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of ZNF473 mRNA CTD PMID:33212167 Zfp473 Rat arsane multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Zfp473 Rat arsenic atom multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Zfp473 Rat atrazine decreases expression ISO ZNF473 (Homo sapiens) 6480464 Atrazine results in decreased expression of ZNF473 mRNA CTD PMID:22378314 Zfp473 Rat benzo[a]pyrene decreases expression ISO Zfp473 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of ZFP473 mRNA CTD PMID:22228805 Zfp473 Rat benzo[a]pyrene increases methylation ISO ZNF473 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ZNF473 3' UTR CTD PMID:27901495 Zfp473 Rat beta-lapachone increases expression ISO ZNF473 (Homo sapiens) 6480464 beta-lapachone results in increased expression of ZNF473 mRNA CTD PMID:38218311 Zfp473 Rat bisphenol A increases expression ISO ZNF473 (Homo sapiens) 6480464 bisphenol A results in increased expression of ZNF473 mRNA CTD PMID:36232920 Zfp473 Rat CGP 52608 multiple interactions ISO ZNF473 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to ZNF473 gene] CTD PMID:28238834 Zfp473 Rat chlorpyrifos decreases expression ISO Zfp473 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of ZFP473 mRNA CTD PMID:37019170 Zfp473 Rat cobalt dichloride increases expression ISO ZNF473 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of ZNF473 mRNA CTD PMID:19320972 Zfp473 Rat copper atom multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of ZNF473 mRNA CTD PMID:20971185 Zfp473 Rat copper(0) multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of ZNF473 mRNA CTD PMID:20971185 Zfp473 Rat copper(II) sulfate increases expression ISO ZNF473 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of ZNF473 mRNA CTD PMID:19549813 Zfp473 Rat CU-O LINKAGE increases expression ISO ZNF473 (Homo sapiens) 6480464 cupric oxide results in increased expression of ZNF473 mRNA CTD PMID:22077320 Zfp473 Rat cyclosporin A increases expression ISO ZNF473 (Homo sapiens) 6480464 Cyclosporine results in increased expression of ZNF473 mRNA CTD PMID:20106945|PMID:25562108 Zfp473 Rat dexamethasone multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... CTD PMID:28628672 Zfp473 Rat doxorubicin decreases expression ISO ZNF473 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of ZNF473 mRNA CTD PMID:29803840 Zfp473 Rat ethyl methanesulfonate increases expression ISO ZNF473 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of ZNF473 mRNA CTD PMID:23649840 Zfp473 Rat formaldehyde increases expression ISO ZNF473 (Homo sapiens) 6480464 Formaldehyde results in increased expression of ZNF473 mRNA CTD PMID:23649840 Zfp473 Rat glyphosate decreases expression EXP 6480464 Glyphosate results in decreased expression of ZFP473 mRNA CTD PMID:38314887 Zfp473 Rat hydrogen peroxide affects expression ISO ZNF473 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of ZNF473 mRNA CTD PMID:20044591 Zfp473 Rat indometacin multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... CTD PMID:28628672 Zfp473 Rat iron dichloride decreases expression ISO ZNF473 (Homo sapiens) 6480464 ferrous chloride results in decreased expression of ZNF473 mRNA CTD PMID:35984750 Zfp473 Rat Licochalcone B increases expression ISO ZNF473 (Homo sapiens) 6480464 licochalcone B results in increased expression of ZNF473 mRNA CTD PMID:33647349 Zfp473 Rat manganese atom multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Zfp473 Rat manganese(0) multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Zfp473 Rat manganese(II) chloride multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Zfp473 Rat methyl methanesulfonate increases expression ISO ZNF473 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of ZNF473 mRNA CTD PMID:23649840 Zfp473 Rat paracetamol increases expression ISO ZNF473 (Homo sapiens) 6480464 Acetaminophen results in increased expression of ZNF473 mRNA CTD PMID:21420995|PMID:22230336 Zfp473 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of ZFP473 mRNA CTD PMID:33387578 Zfp473 Rat PCB138 multiple interactions ISO Zfp473 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Zfp473 Rat potassium chromate increases expression ISO ZNF473 (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of ZNF473 mRNA CTD PMID:22079256 Zfp473 Rat potassium chromate multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of ZNF473 mRNA CTD PMID:22079256 Zfp473 Rat potassium dichromate decreases expression ISO Zfp473 (Mus musculus) 6480464 Potassium Dichromate results in decreased expression of ZFP473 mRNA CTD PMID:23608068 Zfp473 Rat silver atom increases expression ISO ZNF473 (Homo sapiens) 6480464 Silver results in increased expression of ZNF473 mRNA CTD PMID:26014281 Zfp473 Rat silver(0) increases expression ISO ZNF473 (Homo sapiens) 6480464 Silver results in increased expression of ZNF473 mRNA CTD PMID:26014281 Zfp473 Rat sodium arsenite increases expression ISO ZNF473 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ZNF473 mRNA CTD PMID:38568856 Zfp473 Rat sodium arsenite multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Zfp473 Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ZFP473 mRNA CTD PMID:34492290 Zfp473 Rat thiram increases expression ISO ZNF473 (Homo sapiens) 6480464 Thiram results in increased expression of ZNF473 mRNA CTD PMID:38568856 Zfp473 Rat titanium dioxide decreases methylation ISO Zfp473 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of ZFP473 gene CTD PMID:35295148 Zfp473 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of ZFP473 mRNA CTD PMID:33387578 Zfp473 Rat trimellitic anhydride increases expression ISO Zfp473 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of ZFP473 mRNA CTD PMID:19042947 Zfp473 Rat triphenyl phosphate affects expression ISO ZNF473 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ZNF473 mRNA CTD PMID:37042841 Zfp473 Rat triptonide affects expression ISO Zfp473 (Mus musculus) 6480464 triptonide affects the expression of ZFP473 mRNA CTD PMID:33045310 Zfp473 Rat trovafloxacin decreases expression ISO Zfp473 (Mus musculus) 6480464 trovafloxacin results in decreased expression of ZFP473 mRNA CTD PMID:35537566 Zfp473 Rat valproic acid increases expression ISO ZNF473 (Homo sapiens) 6480464 Valproic Acid results in increased expression of ZNF473 mRNA CTD PMID:29154799 Zfp473 Rat valproic acid decreases expression ISO ZNF473 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ZNF473 mRNA CTD PMID:28001369 Zfp473 Rat valproic acid increases methylation ISO ZNF473 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of ZNF473 gene CTD PMID:29154799 Zfp473 Rat zinc atom multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of ZNF473 mRNA CTD PMID:18593933 Zfp473 Rat zinc(0) multiple interactions ISO ZNF473 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of ZNF473 mRNA CTD PMID:18593933