Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rrn3 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RRN3 mRNA] | CTD | PMID:31150632 | Rrn3 | Rat | 1,2-dichloroethane | decreases expression | ISO | Rrn3 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of RRN3 mRNA | CTD | PMID:28960355 | Rrn3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Rrn3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RRN3 mRNA | CTD | PMID:22206623 | Rrn3 | Rat | 17beta-estradiol | decreases phosphorylation | ISO | RRN3 (Homo sapiens) | 6480464 | Estradiol results in decreased phosphorylation of RRN3 protein | CTD | PMID:27026707 | Rrn3 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of RRN3 mRNA | CTD | PMID:31388691 | Rrn3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rrn3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RRN3 mRNA | CTD | PMID:21570461 | Rrn3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RRN3 mRNA | CTD | PMID:32109520 | Rrn3 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of RRN3 mRNA | CTD | PMID:20188158 | Rrn3 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | bisphenol S results in increased expression of RRN3 mRNA | CTD | PMID:39298647 | Rrn3 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of RRN3 mRNA | CTD | PMID:30047161 | Rrn3 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of RRN3 mRNA | CTD | PMID:31881176 | Rrn3 | Rat | aflatoxin B1 | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of RRN3 mRNA | CTD | PMID:19770486 | Rrn3 | Rat | aflatoxin B1 | decreases methylation | ISO | RRN3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of RRN3 gene | CTD | PMID:27153756 | Rrn3 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of RRN3 mRNA | CTD | PMID:23630614 | Rrn3 | Rat | arsane | affects methylation | ISO | RRN3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of RRN3 gene | CTD | PMID:25304211 | Rrn3 | Rat | arsane | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rrn3 | Rat | arsenic atom | affects methylation | ISO | RRN3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of RRN3 gene | CTD | PMID:25304211 | Rrn3 | Rat | arsenic atom | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rrn3 | Rat | arsenite(3-) | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to RRN3 mRNA] | CTD | PMID:32406909 | Rrn3 | Rat | atrazine | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | Atrazine results in increased expression of RRN3 mRNA | CTD | PMID:26518232 | Rrn3 | Rat | benzo[a]pyrene | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RRN3 mRNA | CTD | PMID:19770486|PMID:22228805 | Rrn3 | Rat | benzo[a]pyrene | increases methylation | ISO | RRN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RRN3 promoter | CTD | PMID:27901495 | Rrn3 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RRN3 mRNA | CTD | PMID:25181051 | Rrn3 | Rat | butanal | decreases expression | ISO | RRN3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of RRN3 mRNA | CTD | PMID:26079696 | Rrn3 | Rat | cadmium atom | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RRN3 more ... | CTD | PMID:35301059 | Rrn3 | Rat | cadmium dichloride | decreases expression | ISO | RRN3 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of RRN3 mRNA | CTD | PMID:38382870 | Rrn3 | Rat | cadmium dichloride | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RRN3 more ... | CTD | PMID:33830842|PMID:35301059 | Rrn3 | Rat | cadmium dichloride | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of RRN3 protein | CTD | PMID:33830842 | Rrn3 | Rat | carbon nanotube | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of RRN3 mRNA | CTD | PMID:25554681 | Rrn3 | Rat | cisplatin | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of RRN3 mRNA | CTD | PMID:27392435 | Rrn3 | Rat | copper(II) sulfate | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of RRN3 mRNA | CTD | PMID:19549813 | Rrn3 | Rat | coumarin | increases phosphorylation | ISO | RRN3 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of RRN3 protein | CTD | PMID:35688186 | Rrn3 | Rat | crocidolite asbestos | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in increased expression of RRN3 mRNA | CTD | PMID:18687144 | Rrn3 | Rat | dibenz[a,h]anthracene | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | 1,2,5,6-dibenzanthracene results in increased expression of RRN3 mRNA | CTD | PMID:26377693 | Rrn3 | Rat | dicrotophos | decreases expression | ISO | RRN3 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of RRN3 mRNA | CTD | PMID:28302478 | Rrn3 | Rat | diethylstilbestrol | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | Diethylstilbestrol results in increased expression of RRN3 mRNA | CTD | PMID:22467019 | Rrn3 | Rat | epoxiconazole | decreases expression | ISO | Rrn3 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of RRN3 mRNA | CTD | PMID:35436446 | Rrn3 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of RRN3 mRNA | CTD | PMID:34044035 | Rrn3 | Rat | folic acid | multiple interactions | ISO | Rrn3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RRN3 mRNA | CTD | PMID:22206623 | Rrn3 | Rat | FR900359 | decreases phosphorylation | ISO | RRN3 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of RRN3 protein | CTD | PMID:37730182 | Rrn3 | Rat | manganese atom | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rrn3 | Rat | manganese(0) | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rrn3 | Rat | manganese(II) chloride | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rrn3 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of RRN3 gene | CTD | PMID:35440735 | Rrn3 | Rat | methyl methanesulfonate | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of RRN3 mRNA | CTD | PMID:23649840 | Rrn3 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of RRN3 mRNA | CTD | PMID:24136188 | Rrn3 | Rat | paracetamol | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of RRN3 mRNA | CTD | PMID:26690555 | Rrn3 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Rrn3 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of RRN3 mRNA | CTD | PMID:37995155 | Rrn3 | Rat | perfluorononanoic acid | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of RRN3 mRNA | CTD | PMID:32588087 | Rrn3 | Rat | pirinixic acid | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Rrn3 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of RRN3 mRNA | CTD | PMID:30047161 | Rrn3 | Rat | resveratrol | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of RRN3 mRNA | CTD | PMID:23557933 | Rrn3 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of RRN3 mRNA | CTD | PMID:28374803 | Rrn3 | Rat | senecionine | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | senecionine results in increased expression of RRN3 protein | CTD | PMID:35357534 | Rrn3 | Rat | sodium arsenite | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of RRN3 mRNA | CTD | PMID:38568856 | Rrn3 | Rat | sodium arsenite | multiple interactions | ISO | RRN3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rrn3 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of RRN3 mRNA | CTD | PMID:30047161 | Rrn3 | Rat | sunitinib | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of RRN3 mRNA | CTD | PMID:31533062 | Rrn3 | Rat | tert-butyl hydroperoxide | increases expression | ISO | RRN3 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of RRN3 mRNA | CTD | PMID:29432895 | Rrn3 | Rat | tetrachloromethane | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of RRN3 mRNA | CTD | PMID:27339419 | Rrn3 | Rat | tetrachloromethane | decreases expression | ISO | Rrn3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of RRN3 mRNA | CTD | PMID:31919559 | Rrn3 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of RRN3 mRNA | CTD | PMID:31150632 | Rrn3 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RRN3 mRNA] | CTD | PMID:31150632 | Rrn3 | Rat | tetraphene | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of RRN3 mRNA | CTD | PMID:26377693 | Rrn3 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of RRN3 mRNA | CTD | PMID:34492290 | Rrn3 | Rat | titanium dioxide | decreases methylation | ISO | Rrn3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of RRN3 promoter | CTD | PMID:35295148 | Rrn3 | Rat | triphenyl phosphate | affects expression | ISO | RRN3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of RRN3 mRNA | CTD | PMID:37042841 | Rrn3 | Rat | Triptolide | increases expression | ISO | Rrn3 (Mus musculus) | 6480464 | triptolide results in increased expression of RRN3 mRNA | CTD | PMID:32835833 | Rrn3 | Rat | valproic acid | affects expression | ISO | RRN3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RRN3 mRNA | CTD | PMID:25979313 | Rrn3 | Rat | valproic acid | decreases expression | ISO | RRN3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of RRN3 mRNA | CTD | PMID:37505509 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















