Cox6c (cytochrome c oxidase subunit 6C) - Rat Genome Database

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Gene: Cox6c (cytochrome c oxidase subunit 6C) Rattus norvegicus
Analyze
Symbol: Cox6c
Name: cytochrome c oxidase subunit 6C
RGD ID: 620616
Description: Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in oxidative phosphorylation and proton transmembrane transport. Predicted to be located in mitochondrial membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Orthologous to human COX6C (cytochrome c oxidase subunit 6C); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 1,3-dinitrobenzene; 3,4-methylenedioxymethamphetamine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: COVIc; COX-VIc; Cox6c2; cytochrome c oxidase polypeptide VIc-2; cytochrome c oxidase subunit 6C-2; cytochrome c oxidase, subunit VIc; cytochrome oxidase subunit VIc
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Cox6c-ps1  
Is Marker For: Strains:   SS.LEW-(D7Rat73-D7Rat128)/Ayd   LEW.SS-(D7Rat73-D7Rat128)/Ayd  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8769,014,410 - 69,027,145 (-)NCBIGRCr8
mRatBN7.2767,129,265 - 67,142,001 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl767,111,024 - 67,141,963 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx769,017,776 - 69,030,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0771,220,382 - 71,233,111 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0771,088,251 - 71,100,975 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0774,723,177 - 74,735,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl774,723,179 - 74,735,650 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0774,880,032 - 74,892,505 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4771,465,790 - 71,478,524 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1771,486,526 - 71,498,346 (-)NCBI
Celera764,212,107 - 64,224,807 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-epicatechin-3-O-gallate  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
astaxanthin  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
clofibrate  (ISO)
cocaine  (ISO)
corosolic acid  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
fenthion  (ISO)
folic acid  (ISO)
gallic acid  (ISO)
gallocatechin  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (ISO)
ivermectin  (ISO)
lamivudine  (ISO)
limonene  (EXP)
lipopolysaccharide  (ISO)
methidathion  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
PhIP  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
T-2 toxin  (EXP)
tetrachloromethane  (EXP,ISO)
tetrahydropalmatine  (ISO)
thapsigargin  (EXP,ISO)
thioacetamide  (EXP)
tolcapone  (EXP)
trichloroethene  (EXP)
triptonide  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Construction of a cDNA clone for a nuclear-coded subunit of cytochrome c oxidase from rat liver. Parimoo S, etal., Biochem Biophys Res Commun 1984 Feb 14;118(3):902-9.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Tissue-specific regulation of cytochrome c oxidase subunit expression by thyroid hormone. Sheehan TE, etal., Am J Physiol Endocrinol Metab 2004 Jun;286(6):E968-74. Epub 2004 Feb 17.
Additional References at PubMed
PMID:1300526   PMID:2822403   PMID:2836143   PMID:2854406   PMID:7601105   PMID:8889548   PMID:12477932   PMID:12865426   PMID:14651853   PMID:15277470   PMID:15489334   PMID:16778019  
PMID:18614015   PMID:29476059   PMID:30030519  


Genomics

Comparative Map Data
Cox6c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8769,014,410 - 69,027,145 (-)NCBIGRCr8
mRatBN7.2767,129,265 - 67,142,001 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl767,111,024 - 67,141,963 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx769,017,776 - 69,030,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0771,220,382 - 71,233,111 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0771,088,251 - 71,100,975 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0774,723,177 - 74,735,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl774,723,179 - 74,735,650 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0774,880,032 - 74,892,505 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4771,465,790 - 71,478,524 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1771,486,526 - 71,498,346 (-)NCBI
Celera764,212,107 - 64,224,807 (-)NCBICelera
Cytogenetic Map7q22NCBI
COX6C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38899,877,865 - 99,893,707 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl899,873,200 - 99,893,707 (-)EnsemblGRCh38hg38GRCh38
GRCh378100,890,093 - 100,905,935 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368100,959,548 - 100,975,071 (-)NCBINCBI36Build 36hg18NCBI36
Build 348100,959,547 - 100,975,071NCBI
Celera897,076,023 - 97,092,041 (-)NCBICelera
Cytogenetic Map8q22.2NCBI
HuRef896,092,853 - 96,108,871 (-)NCBIHuRef
CHM1_18100,931,004 - 100,947,023 (-)NCBICHM1_1
T2T-CHM13v2.08101,002,824 - 101,018,666 (-)NCBIT2T-CHM13v2.0
Cox6c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391535,932,122 - 35,938,392 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1535,926,032 - 35,938,392 (-)EnsemblGRCm39 Ensembl
GRCm381535,931,976 - 35,938,246 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1535,925,886 - 35,938,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv371535,861,731 - 35,868,001 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361535,876,565 - 35,882,835 (-)NCBIMGSCv36mm8
Celera1536,558,001 - 36,564,267 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1514.46NCBI
LOC102014046
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541715,230,562 - 15,241,610 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541715,230,562 - 15,241,610 (-)NCBIChiLan1.0ChiLan1.0
LOC100994763
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27117,233,195 - 117,248,888 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1892,772,122 - 92,787,821 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0896,525,872 - 96,541,578 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1898,700,722 - 98,716,662 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl898,700,724 - 98,716,662 (-)Ensemblpanpan1.1panPan2
LOC101970194
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530335,843,593 - 35,854,787 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647043,269,711 - 43,283,683 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647043,269,744 - 43,280,886 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COX6C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl437,074,649 - 37,091,849 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1437,074,619 - 37,089,364 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2439,990,984 - 40,005,771 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103237200
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1894,737,674 - 94,753,239 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603945,937,277 - 45,957,667 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101716380
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247636,850,621 - 6,877,822 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247636,867,602 - 6,877,864 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cox6c
38 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:122
Interacting mature miRNAs:130
Transcripts:ENSRNOT00000014407
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat


Related Rat Strains
The following Strains have been annotated to Cox6c
LEW.SS-(D7Rat73-D7Rat128)/Ayd     SS.LEW-(D7Rat73-D7Rat128)/Ayd    


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2 17 1
Medium 1 26 57 41 19 41 8 10 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AH002156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI716762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF976717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ745239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  K01565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000014407   ⟹   ENSRNOP00000014407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl767,111,024 - 67,141,963 (-)Ensembl
Rnor_6.0 Ensembl774,723,179 - 74,735,650 (-)Ensembl
RefSeq Acc Id: NM_019360   ⟹   NP_062233
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8769,014,410 - 69,027,145 (-)NCBI
mRatBN7.2767,129,265 - 67,142,001 (-)NCBI
Rnor_6.0774,723,177 - 74,735,650 (-)NCBI
Rnor_5.0774,880,032 - 74,892,505 (-)NCBI
RGSC_v3.4771,465,790 - 71,478,524 (-)RGD
Celera764,212,107 - 64,224,807 (-)RGD
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_062233   ⟸   NM_019360
- UniProtKB: Q63703 (UniProtKB/Swiss-Prot),   P11951 (UniProtKB/Swiss-Prot),   A6HR20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014407   ⟸   ENSRNOT00000014407
Protein Domains
Mitochondrial cytochrome c oxidase subunit VIc/VIIs

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P11951-F1-model_v2 AlphaFold P11951 1-76 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695288
Promoter ID:EPDNEW_R5813
Type:multiple initiation site
Name:Cox6c_1
Description:cytochrome c oxidase subunit 6C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0774,735,624 - 74,735,684EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620616 AgrOrtholog
BioCyc Gene G2FUF-33657 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000010807 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055028039 UniProtKB/Swiss-Prot
  ENSRNOG00060009824 UniProtKB/Swiss-Prot
  ENSRNOG00065002189 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014407 ENTREZGENE
  ENSRNOT00000014407.6 UniProtKB/Swiss-Prot
  ENSRNOT00055048514 UniProtKB/Swiss-Prot
  ENSRNOT00060016581 UniProtKB/Swiss-Prot
  ENSRNOT00065002884 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.93.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6922382 IMAGE-MGC_LOAD
InterPro Cytochrome_c_oxidase_VIc/VIIs UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cytochrome_c_oxidase_VIc_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:54322 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72859 IMAGE-MGC_LOAD
NCBI Gene 54322 ENTREZGENE
PANTHER CYTOCHROME C OXIDASE SUBUNIT 6C UniProtKB/Swiss-Prot
  CYTOCHROME C OXIDASE SUBUNIT 6C UniProtKB/Swiss-Prot
  CYTOCHROME C OXIDASE SUBUNIT 6C UniProtKB/TrEMBL
  CYTOCHROME C OXIDASE SUBUNIT 6C UniProtKB/TrEMBL
Pfam COX6C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cox6c PhenoGen
RatGTEx ENSRNOG00000010807 RatGTEx
  ENSRNOG00055028039 RatGTEx
  ENSRNOG00060009824 RatGTEx
  ENSRNOG00065002189 RatGTEx
Superfamily-SCOP Mitochondrial cytochrome c oxidase subunit VIc UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6HR19_RAT UniProtKB/TrEMBL
  A6HR20 ENTREZGENE, UniProtKB/TrEMBL
  CX6C2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q63703 ENTREZGENE
UniProt Secondary Q63703 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Cox6c  cytochrome c oxidase subunit 6C  Cox6c  cytochrome c oxidase, subunit VIc  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Cox6c  cytochrome c oxidase, subunit VIc    cytochrome oxidase subunit VIc  Name updated 1299863 APPROVED
2002-08-07 Cox6c  cytochrome oxidase subunit VIc      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 632578