COX6C (COX6C protein) - Rat Genome Database

Name: COX6C
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: COX6C (COX6C protein) Sus scrofa

Analyze

Symbol:

COX6C

Name:

COX6C protein

RGD ID:

14179532

Description:

INVOLVED IN mitochondrial electron transport, cytochrome c to oxygen (inferred); oxidative phosphorylation (inferred); ASSOCIATED WITH Cohen syndrome (ortholog); FOUND IN mitochondrial respiratory chain complex IV (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Cytochrome c oxidase polypeptide VIc; cytochrome c oxidase subunit 6C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	37,074,649 - 37,091,849 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	37,074,619 - 37,089,364 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	39,990,984 - 40,005,771 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cohen syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitochondrial electron transport, cytochrome c to oxygen (IEA)

oxidative phosphorylation (IEA)

Cellular Component

mitochondrial inner membrane (IEA)

mitochondrial membrane (IEA)

mitochondrial respiratory chain complex IV (IEA,ISO)

mitochondrion (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:30032202

Genomics

Comparative Map Data

COX6C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	37,074,649 - 37,091,849 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	37,074,619 - 37,089,364 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	39,990,984 - 40,005,771 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COX6C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	99,877,865 - 99,893,707 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	99,873,200 - 99,893,707 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	100,890,093 - 100,905,935 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	100,959,548 - 100,975,071 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	100,959,547 - 100,975,071	NCBI
Celera	8	97,076,023 - 97,092,041 (-)	NCBI		Celera
Cytogenetic Map	8	q22.2	NCBI
HuRef	8	96,092,853 - 96,108,871 (-)	NCBI		HuRef
CHM1_1	8	100,931,004 - 100,947,023 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	101,002,824 - 101,018,666 (-)	NCBI		T2T-CHM13v2.0

Cox6c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	35,932,122 - 35,938,392 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	35,926,032 - 35,938,392 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	35,931,976 - 35,938,246 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	35,925,886 - 35,938,246 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	35,861,731 - 35,868,001 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	35,876,565 - 35,882,835 (-)	NCBI		MGSCv36	mm8
Celera	15	36,558,001 - 36,564,267 (-)	NCBI		Celera
Cytogenetic Map	15	B3.1	NCBI
cM Map	15	14.46	NCBI

Cox6c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	69,014,410 - 69,027,145 (-)	NCBI		GRCr8
mRatBN7.2	7	67,129,265 - 67,142,001 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	67,111,024 - 67,141,963 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	69,017,776 - 69,030,505 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	71,220,382 - 71,233,111 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	71,088,251 - 71,100,975 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	74,723,177 - 74,735,650 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	74,723,179 - 74,735,650 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	74,880,032 - 74,892,505 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	71,465,790 - 71,478,524 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	71,486,526 - 71,498,346 (-)	NCBI
Celera	7	64,212,107 - 64,224,807 (-)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

LOC102014046
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	15,230,562 - 15,241,610 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955417	15,230,562 - 15,241,610 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100994763
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	117,233,195 - 117,248,888 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	92,772,122 - 92,787,821 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	96,525,872 - 96,541,578 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	98,700,722 - 98,716,662 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	98,700,724 - 98,716,662 (-)	Ensembl	panpan1.1		panPan2

LOC101970194
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	35,843,593 - 35,854,787 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	43,269,711 - 43,283,683 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	43,269,744 - 43,280,886 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC103237200
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	94,737,674 - 94,753,239 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666039	45,937,277 - 45,957,667 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101716380
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624763	6,850,621 - 6,877,822 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624763	6,867,602 - 6,877,864 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in COX6C
327 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001097473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013996570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK344443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK344745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK392221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU138567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ629154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01087826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HX218717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000095198 ⟹ ENSSSCP00000080138

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	37,074,649 - 37,091,849 (+)	Ensembl

RefSeq Acc Id:

NM_001097473 ⟹ NP_001090942

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	37,074,619 - 37,089,364 (+)	NCBI

Sequence:

show sequence

CTTTATCTTTGCGCCTGCGCGGTGCTGGAACCCCGTCCATTTCTCCGTCAGTCTGCAAGGACGT
TGTTGTGGAGCTGTCAAGGAGAAAAATTACCATGGCTACTAGTTCTTTGACCAAACCTCAGATG
CGTGGCCTTCTGGCCAAGCGTCTGCGATTTCATATTGTTGGAGCATTCATTGTCTCATTGGGGG
TTGCAACTTTCTATAAGTTTGCTGTGGCTGAACCAAGAAAGAAGGCATACGCAGATTTCTACAG
AAATTATGATTCCATGAAAGATTTTGAGGAGATGAGGAAGGCTGGTATCTTTCAGAGTGCGAAG
TGATTTTGGAATGTAAAGAATTTCTTTGGGTTGAGTTCCATGGAAGTTTGTCACTTAACCATTT
TCCTGAACTGTGAAACTATGAGCTCCAAGTATCTGGGCTAAGAAGTAGTTTCTCTTGATAAATA
AACAGTTAACAAATACTGTGAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_013996570 ⟹ XP_013852024

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	37,074,722 - 37,089,364 (+)	NCBI

Sequence:

show sequence

TTGGTTTCACCTTATTGCCGCCTCCCGCTGCCGGCCCTTGGTCTGCTTTGGACTGTCAAGGAGA
AAAATTACCATGGCTACTAGTTCTTTGACCAAACCTCAGATGCGTGGCCTTCTGGCCAAGCGTC
TGCGATTTCATATTGTTGGAGCATTCATTGTCTCATTGGGGGTTGCAACTTTCTATAAGTTTGC
TGTGGCTGAACCAAGAAAGAAGGCATACGCAGATTTCTACAGAAATTATGATTCCATGAAAGAT
TTTGAGGAGATGAGGAAGGCTGGTATCTTTCAGAGTGCGAAGTGATTTTGGAATGTAAAGAATT
TCTTTGGGTTGAGTTCCATGGAAGTTTGTCACTTAACCATTTTCCTGAACTGTGAAACTATGAG
CTCCAAGTATCTGGGCTAAGAAGTAGTTTCTCTTGATAAATAAACAGTTAACAAATACTGTGAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001090942	(Get FASTA)	NCBI Sequence Viewer
	XP_013852024	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A1XQT2	(Get FASTA)	NCBI Sequence Viewer
	ABK55638	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000080138
	ENSSSCP00000080138.1
	ENSSSCP00005036238.1
	ENSSSCP00005036243.1
	ENSSSCP00005036271.1
	ENSSSCP00015022817.1
	ENSSSCP00030000207.1
	ENSSSCP00060033977.1
	ENSSSCP00070020139.1

RefSeq Acc Id:	NP_001090942 ⟸ NM_001097473
- UniProtKB:	A1XQT2 (UniProtKB/Swiss-Prot), A0A4X1TXH1 (UniProtKB/TrEMBL), A0A8W4FML3 (UniProtKB/TrEMBL), A0A8D1BQK2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATSSLTKPQMRGLLAKRLRFHIVGAFIVSLGVATFYKFAVAEPRKKAYADFYRNYDSMKDFEE MRKAGIFQSAK hide sequence

RefSeq Acc Id:	XP_013852024 ⟸ XM_013996570
- Peptide Label:	isoform X1
- UniProtKB:	A1XQT2 (UniProtKB/Swiss-Prot), A0A4X1TXH1 (UniProtKB/TrEMBL), A0A8W4FML3 (UniProtKB/TrEMBL), A0A8D1BQK2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATSSLTKPQMRGLLAKRLRFHIVGAFIVSLGVATFYKFAVAEPRKKAYADFYRNYDSMKDFEE MRKAGIFQSAK hide sequence

RefSeq Acc Id:

ENSSSCP00000080138 ⟸ ENSSSCT00000095198

Protein Domains

Mitochondrial cytochrome c oxidase subunit VIc/VIIs

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000060790	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005036737	UniProtKB/TrEMBL
	ENSSSCG00015042457	UniProtKB/TrEMBL
	ENSSSCG00030000222	UniProtKB/TrEMBL
	ENSSSCG00060057725	UniProtKB/TrEMBL
	ENSSSCG00070012438	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000095198	ENTREZGENE
	ENSSSCT00000095198.1	UniProtKB/TrEMBL
	ENSSSCT00005058660.1	UniProtKB/TrEMBL
	ENSSSCT00005058671.1	UniProtKB/TrEMBL
	ENSSSCT00005058708.1	UniProtKB/TrEMBL
	ENSSSCT00015056951.1	UniProtKB/TrEMBL
	ENSSSCT00030000340.1	UniProtKB/TrEMBL
	ENSSSCT00060078641.1	UniProtKB/TrEMBL
	ENSSSCT00070024338.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.93.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Cytochrome_c_oxidase_VIc/VIIs	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cytochrome_c_oxidase_VIc_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	ssc:100037989	UniProtKB/TrEMBL
NCBI Gene	COX6C	ENTREZGENE
PANTHER	CYTOCHROME C OXIDASE SUBUNIT 6C	UniProtKB/Swiss-Prot
	CYTOCHROME C OXIDASE SUBUNIT 6C	UniProtKB/Swiss-Prot
	CYTOCHROME C OXIDASE SUBUNIT 6C	UniProtKB/TrEMBL
	CYTOCHROME C OXIDASE SUBUNIT 6C	UniProtKB/TrEMBL
Pfam	COX6C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF81415	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A4X1TXH1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1BQK2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8W4FML3	ENTREZGENE
	A1XQT2	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	A0A8W4FML3	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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