Sgk2 (serum/glucocorticoid regulated kinase 2) - Rat Genome Database

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Gene: Sgk2 (serum/glucocorticoid regulated kinase 2) Rattus norvegicus
Analyze
Symbol: Sgk2
Name: serum/glucocorticoid regulated kinase 2
RGD ID: 620232
Description: Predicted to enable potassium channel regulator activity and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in nucleoplasm. Orthologous to human SGK2 (serum/glucocorticoid regulated kinase 2); INTERACTS WITH 17beta-estradiol; 2,4,6-trinitrotoluene; 2-amino-4,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: serine/threonine-protein kinase Sgk2; serum/glucocorticoid-regulated kinase 2; SGK2, serine/threonine kinase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83172,063,625 - 172,089,000 (+)NCBIGRCr8
mRatBN7.23151,644,102 - 151,669,480 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3151,644,102 - 151,669,480 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3155,452,311 - 155,477,655 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03163,951,255 - 163,976,603 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03161,694,860 - 161,720,202 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03159,361,313 - 159,385,843 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3159,368,273 - 159,384,775 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03165,557,662 - 165,581,916 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43153,849,825 - 153,890,111 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13153,778,278 - 153,794,932 (+)NCBI
Celera3150,301,782 - 150,326,821 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrotoluene  (EXP)
2-amino-4,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
ammonium chloride  (EXP)
ampicillin  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atorvastatin calcium  (ISO)
azoxystrobin  (ISO)
barium(0)  (ISO)
benzo[a]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clothianidin  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
dextran sulfate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
fenofibrate  (ISO)
fluvastatin  (ISO)
glucose  (ISO)
glutathione  (EXP)
GW 4064  (ISO)
hydrogen peroxide  (ISO)
isotretinoin  (ISO)
Licochalcone B  (ISO)
menadione  (ISO)
metformin  (EXP)
methylmercury chloride  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
ouabain  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PCB138  (EXP)
perfluorohexanesulfonic acid  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium atom  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
quinolin-8-ol  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
troglitazone  (EXP,ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12397388   PMID:15057822   PMID:19447520   PMID:20926631  


Genomics

Comparative Map Data
Sgk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83172,063,625 - 172,089,000 (+)NCBIGRCr8
mRatBN7.23151,644,102 - 151,669,480 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3151,644,102 - 151,669,480 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3155,452,311 - 155,477,655 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03163,951,255 - 163,976,603 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03161,694,860 - 161,720,202 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03159,361,313 - 159,385,843 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3159,368,273 - 159,384,775 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03165,557,662 - 165,581,916 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43153,849,825 - 153,890,111 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13153,778,278 - 153,794,932 (+)NCBI
Celera3150,301,782 - 150,326,821 (+)NCBICelera
Cytogenetic Map3q42NCBI
SGK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382043,559,027 - 43,585,627 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2043,558,968 - 43,588,237 (+)EnsemblGRCh38hg38GRCh38
GRCh372042,187,667 - 42,214,267 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362041,621,100 - 41,647,687 (+)NCBINCBI36Build 36hg18NCBI36
Build 342041,621,099 - 41,647,686NCBI
Celera2038,895,152 - 38,921,737 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2038,923,264 - 38,950,126 (+)NCBIHuRef
CHM1_12042,091,437 - 42,118,025 (+)NCBICHM1_1
T2T-CHM13v2.02045,292,229 - 45,318,829 (+)NCBIT2T-CHM13v2.0
Sgk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392162,829,249 - 162,856,059 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2162,829,250 - 162,856,047 (+)EnsemblGRCm39 Ensembl
GRCm382162,987,327 - 163,014,139 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2162,987,330 - 163,014,127 (+)EnsemblGRCm38mm10GRCm38
MGSCv372162,813,217 - 162,839,863 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362162,678,987 - 162,705,568 (+)NCBIMGSCv36mm8
Celera2168,934,488 - 168,961,119 (+)NCBICelera
Cytogenetic Map2H2NCBI
cM Map283.93NCBI
Sgk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544513,581,145 - 13,625,320 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544513,581,145 - 13,625,320 (-)NCBIChiLan1.0ChiLan1.0
SGK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22149,304,906 - 49,331,003 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12049,298,365 - 49,324,092 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02039,897,338 - 39,924,767 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12040,992,171 - 41,018,587 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2040,997,536 - 41,018,587 (+)Ensemblpanpan1.1panPan2
SGK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12431,272,395 - 31,294,409 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2431,272,493 - 31,294,195 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2430,916,070 - 30,938,174 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02431,986,104 - 32,001,288 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2431,980,261 - 32,001,114 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12431,243,810 - 31,265,914 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02431,355,174 - 31,377,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02431,895,633 - 31,917,764 (+)NCBIUU_Cfam_GSD_1.0
Sgk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640180,280,673 - 180,302,503 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365303,008,161 - 3,024,218 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365303,007,934 - 3,025,552 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1746,188,265 - 46,208,804 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11746,188,160 - 46,208,807 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21751,626,067 - 51,649,666 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SGK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1220,217,768 - 20,245,675 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl220,218,420 - 20,246,186 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605068,961,022 - 68,988,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479010,726,486 - 10,752,235 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479010,727,125 - 10,749,060 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sgk2
439 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:541
Count of miRNA genes:281
Interacting mature miRNAs:361
Transcripts:ENSRNOT00000041688
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat

Markers in Region
RH140959  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23151,669,089 - 151,669,271 (+)MAPPERmRatBN7.2
Rnor_6.03159,385,453 - 159,385,634NCBIRnor6.0
Rnor_5.03165,581,526 - 165,581,707UniSTSRnor5.0
RGSC_v3.43153,889,721 - 153,889,902UniSTSRGSC3.4
Celera3150,326,431 - 150,326,612UniSTS
RH 3.4 Map31388.3UniSTS
Cytogenetic Map3q42UniSTS
AA891709  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23151,654,302 - 151,654,514 (+)MAPPERmRatBN7.2
Rnor_6.03159,371,555 - 159,371,766NCBIRnor6.0
Rnor_5.03165,567,628 - 165,567,839UniSTSRnor5.0
RGSC_v3.43153,874,936 - 153,875,147UniSTSRGSC3.4
Celera3150,311,646 - 150,311,857UniSTS
RH 3.4 Map31389.0UniSTS
Cytogenetic Map3q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 22 22 22 23
Low 2 24 19 2 19 27 8 7 10
Below cutoff 1 10 8 4 5 8 4 23 1 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000041688   ⟹   ENSRNOP00000040718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3151,651,515 - 151,669,480 (+)Ensembl
Rnor_6.0 Ensembl3159,368,273 - 159,384,775 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095429   ⟹   ENSRNOP00000090611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3151,644,102 - 151,669,480 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108319   ⟹   ENSRNOP00000081213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3151,644,102 - 151,669,480 (+)Ensembl
RefSeq Acc Id: NM_134463   ⟹   NP_604458
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,063,625 - 172,089,000 (+)NCBI
mRatBN7.23151,644,102 - 151,669,480 (+)NCBI
Rnor_6.03159,361,313 - 159,385,843 (+)NCBI
Rnor_5.03165,557,662 - 165,581,916 (+)NCBI
RGSC_v3.43153,849,825 - 153,890,111 (+)RGD
Celera3150,301,782 - 150,326,821 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_604458 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL91351 (Get FASTA)   NCBI Sequence Viewer  
  EDL96598 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040718.5
  ENSRNOP00000081213
  ENSRNOP00000081213.1
  ENSRNOP00000090611.1
GenBank Protein Q8R4U9 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_604458   ⟸   NM_134463
- UniProtKB: Q8R4U9 (UniProtKB/Swiss-Prot),   A6JX11 (UniProtKB/TrEMBL),   A0A8I6A9X9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000040718   ⟸   ENSRNOT00000041688
RefSeq Acc Id: ENSRNOP00000090611   ⟸   ENSRNOT00000095429
RefSeq Acc Id: ENSRNOP00000081213   ⟸   ENSRNOT00000108319
Protein Domains
AGC-kinase C-terminal   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R4U9-F1-model_v2 AlphaFold Q8R4U9 1-367 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620232 AgrOrtholog
BioCyc Gene G2FUF-46926 BioCyc
Ensembl Genes ENSRNOG00000033573 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041688.6 UniProtKB/TrEMBL
  ENSRNOT00000095429.1 UniProtKB/TrEMBL
  ENSRNOT00000108319 ENTREZGENE
  ENSRNOT00000108319.1 UniProtKB/Swiss-Prot
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171497 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 171497 ENTREZGENE
PANTHER RIBOSOMAL PROTEIN S6 KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SERUM/GLUCOCORTICOID REGULATED KINASE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sgk2 PhenoGen
PROSITE AGC_KINASE_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033573 RatGTEx
SMART S_TK_X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A9X9 ENTREZGENE, UniProtKB/TrEMBL
  A6JX11 ENTREZGENE, UniProtKB/TrEMBL
  Q8R4U9 ENTREZGENE
  R9PXX7_RAT UniProtKB/TrEMBL
  SGK2_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 Sgk2  serum/glucocorticoid regulated kinase 2  Sgk2  SGK2, serine/threonine kinase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-05-12 Sgk2  SGK2, serine/threonine kinase 2  Sgk2  serum/glucocorticoid regulated kinase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Sgk2  serum/glucocorticoid regulated kinase 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Sgk2  serum/glucocorticoid regulated kinase 2      Symbol and Name status set to provisional 70820 PROVISIONAL