Vps25 (vacuolar protein sorting 25 homolog) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Vps25 (vacuolar protein sorting 25 homolog) Rattus norvegicus
Analyze
Symbol: Vps25
Name: vacuolar protein sorting 25 homolog
RGD ID: 1584685
Description: Predicted to enable protein homodimerization activity and structural molecule activity. Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in cytosol; endosome membrane; and nucleus. Predicted to be part of ESCRT II complex. Orthologous to human VPS25 (vacuolar protein sorting 25 homolog); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ELL-associated protein of 20 kDa; ESCRT-II complex subunit VPS25; LOC681059; similar to Vacuolar protein sorting protein 25 (ELL-associated protein of 20 kDa); vacuolar protein sorting 25; vacuolar protein sorting 25 (S. cerevisiae); vacuolar protein sorting 25 homolog (S. cerevisiae); vacuolar protein-sorting-associated protein 25
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,696,330 - 86,701,871 (+)NCBIGRCr8
mRatBN7.21086,196,062 - 86,201,606 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,188,812 - 86,231,829 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,234,035 - 91,239,520 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,708,548 - 90,714,031 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,101,709 - 86,107,192 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,174,684 - 89,180,165 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,174,684 - 89,180,160 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,973,180 - 88,978,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,277,207 - 90,288,162 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1084,913,038 - 84,918,528 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11278625   PMID:14519844   PMID:14651853   PMID:15057822   PMID:15489334   PMID:16371348   PMID:16973552   PMID:17010938   PMID:19056867   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Vps25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,696,330 - 86,701,871 (+)NCBIGRCr8
mRatBN7.21086,196,062 - 86,201,606 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,188,812 - 86,231,829 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,234,035 - 91,239,520 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,708,548 - 90,714,031 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,101,709 - 86,107,192 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,174,684 - 89,180,165 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,174,684 - 89,180,160 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,973,180 - 88,978,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,277,207 - 90,288,162 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1084,913,038 - 84,918,528 (+)NCBICelera
Cytogenetic Map10q31NCBI
VPS25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,773,449 - 42,779,599 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,773,449 - 42,779,599 (+)EnsemblGRCh38hg38GRCh38
GRCh371740,925,467 - 40,931,617 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,178,980 - 38,185,143 (+)NCBINCBI36Build 36hg18NCBI36
Celera1737,581,441 - 37,587,604 (+)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1736,689,949 - 36,696,113 (+)NCBIHuRef
CHM1_11741,161,040 - 41,167,204 (+)NCBICHM1_1
T2T-CHM13v2.01743,630,589 - 43,636,739 (+)NCBIT2T-CHM13v2.0
Vps25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,144,533 - 101,150,377 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,144,533 - 101,150,375 (+)EnsemblGRCm39 Ensembl
GRCm3811101,252,326 - 101,259,551 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,253,707 - 101,259,549 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711101,115,057 - 101,120,860 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611101,069,833 - 101,075,636 (+)NCBIMGSCv36mm8
MGSCv3611102,032,190 - 102,038,205 (+)NCBIMGSCv36mm8
Celera11112,549,939 - 112,551,229 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1164.48NCBI
Vps25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,589,509 - 16,594,497 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,589,509 - 16,593,730 (+)NCBIChiLan1.0ChiLan1.0
VPS25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,206,197 - 22,212,397 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,096,294 - 24,102,499 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,538,322 - 14,544,573 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,763,523 - 14,769,672 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,763,523 - 14,769,672 (-)Ensemblpanpan1.1panPan2
Vps25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,583,447 - 19,589,169 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,486,003 - 17,491,689 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,486,009 - 17,491,692 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VPS25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,082,865 - 20,088,566 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,082,864 - 20,088,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,339,869 - 20,342,699 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VPS25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,512,161 - 63,520,923 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,511,674 - 63,521,093 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,304,232 - 34,310,429 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vps25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,428,448 - 1,432,574 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,428,448 - 1,432,583 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Vps25
20 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:331
Count of miRNA genes:202
Interacting mature miRNAs:224
Transcripts:ENSRNOT00000027770, ENSRNOT00000027804, ENSRNOT00000043754
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)107563188787055282Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
631555Bp134Blood pressure QTL 1340.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)108051528791230079Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)107877551698279596Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)107889965587307728Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107437208494965338Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1085565469103884409Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
2301398Kidm38Kidney mass QTL 380.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)108400727295933025Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)108402232193995963Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107255241693995749Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
4889948Bss91Bone structure and strength QTL 914tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)108256485692369470Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1080515287101325465Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107624608594965338Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
12880055Am11Aortic mass QTL 110.004aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)108400727295933025Rat

Markers in Region
RH128509  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21086,201,392 - 86,201,583 (+)MAPPERmRatBN7.2
Rnor_6.01089,179,952 - 89,180,142NCBIRnor6.0
Rnor_5.01088,978,448 - 88,978,638UniSTSRnor5.0
RGSC_v3.41090,287,947 - 90,288,137UniSTSRGSC3.4
Celera1084,918,315 - 84,918,505UniSTS
RH 3.4 Map10877.1UniSTS
Cytogenetic Map10q32.1UniSTS
AW107467  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21086,201,138 - 86,201,230 (+)MAPPERmRatBN7.2
Rnor_6.01089,179,698 - 89,179,789NCBIRnor6.0
Rnor_5.01088,978,194 - 88,978,285UniSTSRnor5.0
RGSC_v3.41090,287,693 - 90,287,784UniSTSRGSC3.4
Celera1084,918,061 - 84,918,152UniSTS
Cytogenetic Map10q32.1UniSTS
MARC_24031-24032:1029960467:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21086,198,291 - 86,199,177 (+)MAPPERmRatBN7.2
Rnor_6.01089,176,855 - 89,177,739NCBIRnor6.0
Rnor_5.01088,975,351 - 88,976,235UniSTSRnor5.0
RGSC_v3.41090,284,847 - 90,285,731UniSTSRGSC3.4
Celera1084,915,209 - 84,916,095UniSTS
Cytogenetic Map10q32.1UniSTS
MARC_27470-27471:1034353500:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21086,198,296 - 86,199,193 (+)MAPPERmRatBN7.2
Rnor_6.01089,176,860 - 89,177,755NCBIRnor6.0
Rnor_5.01088,975,356 - 88,976,251UniSTSRnor5.0
RGSC_v3.41090,284,852 - 90,285,747UniSTSRGSC3.4
Celera1084,915,214 - 84,916,111UniSTS
Cytogenetic Map10q32.1UniSTS
RH124894  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21086,201,327 - 86,201,466 (+)MAPPERmRatBN7.2
Rnor_6.01089,179,887 - 89,180,025NCBIRnor6.0
Rnor_5.01088,978,383 - 88,978,521UniSTSRnor5.0
RGSC_v3.41090,287,882 - 90,288,020UniSTSRGSC3.4
Celera1084,918,250 - 84,918,388UniSTS
Cytogenetic Map10q32.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2
Low 3 43 57 41 19 41 8 11 74 35 37 11 8
Below cutoff 2

Sequence


RefSeq Acc Id: ENSRNOT00000027770   ⟹   ENSRNOP00000027770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,202,693 - 86,219,629 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000043754   ⟹   ENSRNOP00000044397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,188,854 - 86,201,601 (+)Ensembl
Rnor_6.0 Ensembl1089,174,684 - 89,180,160 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000043953   ⟹   ENSRNOP00000043210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,188,812 - 86,190,687 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1089,175,017 - 89,177,429 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1089,176,873 - 89,178,644 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075953   ⟹   ENSRNOP00000068003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,196,099 - 86,201,598 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076056   ⟹   ENSRNOP00000080834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,203,829 - 86,231,829 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076366   ⟹   ENSRNOP00000068513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,202,693 - 86,231,829 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,196,268 - 86,201,598 (+)Ensembl
Rnor_6.0 Ensembl1089,174,694 - 89,177,771 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,195,281 - 86,200,277 (+)Ensembl
Rnor_6.0 Ensembl1089,174,691 - 89,178,134 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078931   ⟹   ENSRNOP00000072084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1086,196,048 - 86,231,812 (+)Ensembl
RefSeq Acc Id: NM_001173451   ⟹   NP_001166922
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81086,696,387 - 86,701,871 (+)NCBI
mRatBN7.21086,196,120 - 86,201,606 (+)NCBI
Rnor_6.01089,174,684 - 89,180,165 (+)NCBI
Rnor_5.01088,973,180 - 88,978,661 (+)NCBI
Celera1084,913,038 - 84,918,528 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039086821   ⟹   XP_038942749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81086,696,330 - 86,701,867 (+)NCBI
mRatBN7.21086,196,062 - 86,200,105 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001166922 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942749 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000044397.4
  ENSRNOP00000068003
  ENSRNOP00000068003.2
  ENSRNOP00000072084.2
  ENSRNOP00000082243.1
  ENSRNOP00000095750.1
GenBank Protein P0C0A1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001166922   ⟸   NM_001173451
- UniProtKB: P0C0A1 (UniProtKB/Swiss-Prot),   A0A096MJ61 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000044397   ⟸   ENSRNOT00000043754
RefSeq Acc Id: XP_038942749   ⟸   XM_039086821
- Peptide Label: isoform X1
- UniProtKB: A6HJ97 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000027770   ⟸   ENSRNOT00000027770
RefSeq Acc Id: ENSRNOP00000068513   ⟸   ENSRNOT00000076366
RefSeq Acc Id: ENSRNOP00000043210   ⟸   ENSRNOT00000043953
RefSeq Acc Id: ENSRNOP00000072084   ⟸   ENSRNOT00000078931
RefSeq Acc Id: ENSRNOP00000068003   ⟸   ENSRNOT00000075953
RefSeq Acc Id: ENSRNOP00000080834   ⟸   ENSRNOT00000076056
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C0A1-F1-model_v2 AlphaFold P0C0A1 1-176 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697750
Promoter ID:EPDNEW_R8272
Type:multiple initiation site
Name:Vps25_1
Description:vacuolar protein sorting 25 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01089,174,697 - 89,174,757EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584685 AgrOrtholog
BioCyc Gene G2FUF-23188 BioCyc
Ensembl Genes ENSRNOG00000020441 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000051179 Ensembl
Ensembl Transcript ENSRNOT00000043754.5 UniProtKB/TrEMBL
  ENSRNOT00000075953 ENTREZGENE
  ENSRNOT00000075953.2 UniProtKB/TrEMBL
  ENSRNOT00000076658.3 UniProtKB/TrEMBL
  ENSRNOT00000076944.3 UniProtKB/TrEMBL
  ENSRNOT00000078931.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.10.570 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin-like UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Cyclin-like_sf UniProtKB/TrEMBL
  ESCRT-II_cplx_Vps25-sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ESCRT-II_cplx_Vps25-sub_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Kinase_OSR1/WNK_CCT UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:681059 UniProtKB/Swiss-Prot
NCBI Gene 681059 ENTREZGENE
PANTHER PTHR13149 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE WNK4 UniProtKB/TrEMBL
  VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ESCRT-II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OSR1_C UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PhenoGen Vps25 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020441 RatGTEx
  ENSRNOG00000051179 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47954 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A096MJ61 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K231_RAT UniProtKB/TrEMBL
  A0A8I5ZT86_RAT UniProtKB/TrEMBL
  A0A8I6APN0_RAT UniProtKB/TrEMBL
  A0A8L2QP36_RAT UniProtKB/TrEMBL
  A6HJ97 ENTREZGENE, UniProtKB/TrEMBL
  P0C0A1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-19 Vps25  vacuolar protein sorting 25 homolog  Vps25  vacuolar protein sorting 25  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-13 Vps25  vacuolar protein sorting 25  Vps25  vacuolar protein sorting 25 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-11 Vps25  vacuolar protein sorting 25 homolog (S. cerevisiae)  Vps25  vacuolar protein sorting 25 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Vps25  vacuolar protein sorting 25 (S. cerevisiae)  LOC681059  similar to Vacuolar protein sorting protein 25 (ELL-associated protein of 20 kDa)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC681059  similar to Vacuolar protein sorting protein 25 (ELL-associated protein of 20 kDa)      Symbol and Name status set to provisional 70820 PROVISIONAL