Atp6v1c2 (ATPase H+ transporting V1 subunit C2) - Rat Genome Database

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Gene: Atp6v1c2 (ATPase H+ transporting V1 subunit C2) Rattus norvegicus
Analyze
Symbol: Atp6v1c2
Name: ATPase H+ transporting V1 subunit C2
RGD ID: 1359430
Description: Predicted to enable identical protein binding activity and proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in positive regulation of Wnt signaling pathway. Predicted to act upstream of or within proton transmembrane transport. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Orthologous to human ATP6V1C2 (ATPase H+ transporting V1 subunit C2); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATPase, H+ transporting, lysosomal V1 subunit C2; ATPase, H+ transporting, V1 subunit C; ATPase, H+ transporting, V1 subunit C, isoform 2; LOC362802; similar to RIKEN cDNA 1110038G14; V-ATPase subunit C 2; V-type ATPase C2 subunit a isoform; V-type proton ATPase subunit C 2; vacuolar H+ ATPase C2; vacuolar proton pump subunit C 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8645,809,269 - 45,872,914 (-)NCBIGRCr8
mRatBN7.2640,080,545 - 40,144,199 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,080,547 - 40,120,028 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx640,407,983 - 40,447,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0640,722,678 - 40,762,133 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0640,155,927 - 40,195,380 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0642,585,452 - 42,632,289 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl642,585,934 - 42,630,983 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0652,307,211 - 52,351,972 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera639,381,677 - 39,420,442 (-)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
7. Mouse proton pump ATPase C subunit isoforms (C2-a and C2-b) specifically expressed in kidney and lung. Sun-Wada GH, etal., J Biol Chem 2003 Nov 7;278(45):44843-51. Epub 2003 Aug 28.
Additional References at PubMed
PMID:12527205   PMID:16283434   PMID:17897319   PMID:19056867   PMID:20093472   PMID:21356312   PMID:23376485  


Genomics

Comparative Map Data
Atp6v1c2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8645,809,269 - 45,872,914 (-)NCBIGRCr8
mRatBN7.2640,080,545 - 40,144,199 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,080,547 - 40,120,028 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx640,407,983 - 40,447,436 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0640,722,678 - 40,762,133 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0640,155,927 - 40,195,380 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0642,585,452 - 42,632,289 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl642,585,934 - 42,630,983 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0652,307,211 - 52,351,972 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera639,381,677 - 39,420,442 (-)NCBICelera
Cytogenetic Map6q16NCBI
ATP6V1C2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38210,720,943 - 10,785,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl210,721,100 - 10,785,110 (+)EnsemblGRCh38hg38GRCh38
GRCh37210,861,756 - 10,925,236 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36210,779,226 - 10,842,687 (+)NCBINCBI36Build 36hg18NCBI36
Build 34210,812,420 - 10,875,832NCBI
Celera210,777,001 - 10,840,382 (+)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef210,713,330 - 10,776,550 (+)NCBIHuRef
CHM1_1210,791,519 - 10,854,975 (+)NCBICHM1_1
T2T-CHM13v2.0210,750,978 - 10,815,109 (+)NCBIT2T-CHM13v2.0
Atp6v1c2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391217,334,722 - 17,375,700 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1217,334,722 - 17,379,360 (-)EnsemblGRCm39 Ensembl
GRCm381217,284,721 - 17,325,386 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1217,284,721 - 17,329,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv371217,291,527 - 17,331,536 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361217,310,201 - 17,350,192 (-)NCBIMGSCv36mm8
Celera1217,606,632 - 17,646,929 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map128.06NCBI
Atp6v1c2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,711,235 - 5,735,081 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554875,711,235 - 5,735,081 (+)NCBIChiLan1.0ChiLan1.0
ATP6V1C2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212115,734,027 - 115,825,994 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A115,737,998 - 115,829,120 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A10,689,538 - 10,783,372 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A10,874,395 - 10,936,457 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A10,872,071 - 10,936,457 (+)Ensemblpanpan1.1panPan2
ATP6V1C2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1177,602,348 - 7,653,402 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl177,599,535 - 7,653,402 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha177,526,180 - 7,578,668 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0177,702,415 - 7,755,089 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl177,702,390 - 7,755,089 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1177,589,007 - 7,641,343 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0177,591,391 - 7,643,850 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0177,604,848 - 7,657,564 (+)NCBIUU_Cfam_GSD_1.0
Atp6v1c2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629252,063,348 - 52,116,116 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365326,818,758 - 6,865,959 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365326,818,387 - 6,866,691 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP6V1C2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3125,775,099 - 125,825,244 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13125,774,259 - 125,825,752 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23134,530,646 - 134,581,910 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATP6V1C2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11496,827,671 - 96,894,854 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1496,828,451 - 96,893,116 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604515,398,860 - 15,464,184 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp6v1c2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248654,711,119 - 4,734,740 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248654,711,324 - 4,734,409 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp6v1c2
320 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:162
Count of miRNA genes:113
Interacting mature miRNAs:127
Transcripts:ENSRNOT00000071977
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat

Markers in Region
RH127360  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,080,666 - 40,081,020 (+)MAPPERmRatBN7.2
Rnor_6.0642,586,098 - 42,586,451NCBIRnor6.0
Rnor_5.0652,307,333 - 52,307,686UniSTSRnor5.0
Celera639,381,799 - 39,382,152UniSTS
RH 3.4 Map6185.2UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 25 22 11
Low 3 34 55 39 19 39 4 4 74 10 19 4
Below cutoff 9 2 2 2 4 7 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001014199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY594319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000071977   ⟹   ENSRNOP00000066981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,080,547 - 40,120,028 (-)Ensembl
Rnor_6.0 Ensembl642,585,997 - 42,630,983 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081433   ⟹   ENSRNOP00000071116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,080,547 - 40,120,028 (-)Ensembl
Rnor_6.0 Ensembl642,585,934 - 42,616,548 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099858   ⟹   ENSRNOP00000093823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,080,547 - 40,120,028 (-)Ensembl
RefSeq Acc Id: NM_001014199   ⟹   NP_001014221
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,269 - 45,848,747 (-)NCBI
mRatBN7.2640,080,545 - 40,120,028 (-)NCBI
Rnor_6.0642,585,976 - 42,632,289 (-)NCBI
Rnor_5.0652,307,211 - 52,351,972 (-)NCBI
Celera639,381,677 - 39,420,442 (-)RGD
Sequence:
RefSeq Acc Id: XM_017594241   ⟹   XP_017449730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,848,633 (-)NCBI
mRatBN7.2640,080,545 - 40,119,907 (-)NCBI
Rnor_6.0642,585,501 - 42,631,072 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112599   ⟹   XP_038968527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,914 (-)NCBI
mRatBN7.2640,080,545 - 40,144,199 (-)NCBI
RefSeq Acc Id: XM_039112600   ⟹   XP_038968528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,914 (-)NCBI
mRatBN7.2640,080,545 - 40,144,199 (-)NCBI
RefSeq Acc Id: XM_039112604   ⟹   XP_038968532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,914 (-)NCBI
mRatBN7.2640,080,545 - 40,144,199 (-)NCBI
RefSeq Acc Id: XM_039112607   ⟹   XP_038968535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,847,400 (-)NCBI
mRatBN7.2640,080,545 - 40,118,685 (-)NCBI
RefSeq Acc Id: XM_063262165   ⟹   XP_063118235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,872 (-)NCBI
RefSeq Acc Id: XM_063262166   ⟹   XP_063118236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,864 (-)NCBI
RefSeq Acc Id: XM_063262167   ⟹   XP_063118237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,894 (-)NCBI
RefSeq Acc Id: XM_063262168   ⟹   XP_063118238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,848,630 (-)NCBI
RefSeq Acc Id: XM_063262169   ⟹   XP_063118239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,865 (-)NCBI
RefSeq Acc Id: XM_063262170   ⟹   XP_063118240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,871 (-)NCBI
RefSeq Acc Id: XM_063262171   ⟹   XP_063118241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,914 (-)NCBI
RefSeq Acc Id: XM_063262172   ⟹   XP_063118242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,864 (-)NCBI
RefSeq Acc Id: XM_063262173   ⟹   XP_063118243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,914 (-)NCBI
RefSeq Acc Id: XM_063262174   ⟹   XP_063118244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,894 (-)NCBI
RefSeq Acc Id: XM_063262175   ⟹   XP_063118245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,809,289 - 45,872,865 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001014221   ⟸   NM_001014199
- UniProtKB: Q53B80 (UniProtKB/Swiss-Prot),   Q6AYE4 (UniProtKB/Swiss-Prot),   A0A0G2JZN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449730   ⟸   XM_017594241
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JZN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071116   ⟸   ENSRNOT00000081433
RefSeq Acc Id: ENSRNOP00000066981   ⟸   ENSRNOT00000071977
RefSeq Acc Id: XP_038968528   ⟸   XM_039112600
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JZN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968532   ⟸   XM_039112604
- Peptide Label: isoform X2
- UniProtKB: Q6AYE4 (UniProtKB/Swiss-Prot),   Q53B80 (UniProtKB/Swiss-Prot),   A0A0G2JZN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968527   ⟸   XM_039112599
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JZN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968535   ⟸   XM_039112607
- Peptide Label: isoform X5
- UniProtKB: M0RBN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000093823   ⟸   ENSRNOT00000099858
RefSeq Acc Id: XP_063118243   ⟸   XM_063262173
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118241   ⟸   XM_063262171
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118237   ⟸   XM_063262167
- Peptide Label: isoform X2
- UniProtKB: Q6AYE4 (UniProtKB/Swiss-Prot),   Q53B80 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063118244   ⟸   XM_063262174
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118235   ⟸   XM_063262165
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118240   ⟸   XM_063262170
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118239   ⟸   XM_063262169
- Peptide Label: isoform X2
- UniProtKB: Q6AYE4 (UniProtKB/Swiss-Prot),   Q53B80 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063118245   ⟸   XM_063262175
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118242   ⟸   XM_063262172
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118236   ⟸   XM_063262166
- Peptide Label: isoform X2
- UniProtKB: Q6AYE4 (UniProtKB/Swiss-Prot),   Q53B80 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063118238   ⟸   XM_063262168
- Peptide Label: isoform X2
- UniProtKB: Q6AYE4 (UniProtKB/Swiss-Prot),   Q53B80 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYE4-F1-model_v2 AlphaFold Q6AYE4 1-425 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359430 AgrOrtholog
BioCyc Gene G2FUF-38057 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000050553 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055005725 UniProtKB/Swiss-Prot
  ENSRNOG00060003957 UniProtKB/Swiss-Prot
  ENSRNOG00065005630 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000071977 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000071977.3 UniProtKB/Swiss-Prot
  ENSRNOT00000081433.2 UniProtKB/TrEMBL
  ENSRNOT00000099858.1 UniProtKB/Swiss-Prot
  ENSRNOT00055009247 UniProtKB/Swiss-Prot
  ENSRNOT00060006609 UniProtKB/Swiss-Prot
  ENSRNOT00065008397 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  subunit c (vma5p) of the yeast v-atpase, domain 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7122992 IMAGE-MGC_LOAD
InterPro ATPase_V1-cplx_csu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vac_ATP_synth_c_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362802 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94046 IMAGE-MGC_LOAD
NCBI Gene 362802 ENTREZGENE
PANTHER PTHR10137 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE SUBUNIT C 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam V-ATPase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atp6v1c2 PhenoGen
RatGTEx ENSRNOG00000050553 RatGTEx
  ENSRNOG00055005725 RatGTEx
  ENSRNOG00060003957 RatGTEx
  ENSRNOG00065005630 RatGTEx
Superfamily-SCOP SSF118203 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JZN3 ENTREZGENE, UniProtKB/TrEMBL
  A6HAU4_RAT UniProtKB/TrEMBL
  A6HAU5_RAT UniProtKB/TrEMBL
  M0RBN8 ENTREZGENE, UniProtKB/TrEMBL
  Q53B80 ENTREZGENE
  Q6AYE4 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q53B80 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Atp6v1c2  ATPase H+ transporting V1 subunit C2  Atp6v1c2  ATPase, H+ transporting, lysosomal V1 subunit C2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Atp6v1c2  ATPase, H+ transporting, lysosomal V1 subunit C2  Atp6v1c2  ATPase, H+ transporting, V1 subunit C, isoform 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Atp6v1c2  ATPase, H+ transporting, V1 subunit C, isoform 2  LOC362802  similar to RIKEN cDNA 1110038G14  Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC362802  similar to RIKEN cDNA 1110038G14      Symbol and Name status set to provisional 70820 PROVISIONAL