Or1i2 (olfactory receptor family 1 subfamily I member 2) - Rat Genome Database

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Gene: Or1i2 (olfactory receptor family 1 subfamily I member 2) Rattus norvegicus
Analyze
Symbol: Or1i2
Name: olfactory receptor family 1 subfamily I member 2
RGD ID: 1334246
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. Orthologous to human OR1I1 (olfactory receptor family 1 subfamily I member 1); INTERACTS WITH 1,2-dimethylhydrazine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1087; olfactory receptor gene Olr1087; olfactory receptor Olr1087; Olr1087; ratchr7-12543995-12544936_ORF
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,636,515 - 11,637,456 (+)NCBIGRCr8
mRatBN7.2710,985,938 - 10,986,879 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,980,344 - 10,987,036 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,806,473 - 13,807,414 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,683,865 - 15,684,806 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,561,762 - 13,562,703 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,996,966 - 13,997,907 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,996,966 - 13,997,907 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,153,449 - 14,154,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,543,995 - 12,544,936 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,543,994 - 12,544,936 (+)NCBI
Celera79,103,332 - 9,104,273 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or1i2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,636,515 - 11,637,456 (+)NCBIGRCr8
mRatBN7.2710,985,938 - 10,986,879 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,980,344 - 10,987,036 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,806,473 - 13,807,414 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,683,865 - 15,684,806 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,561,762 - 13,562,703 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,996,966 - 13,997,907 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,996,966 - 13,997,907 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,153,449 - 14,154,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,543,995 - 12,544,936 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,543,994 - 12,544,936 (+)NCBI
Celera79,103,332 - 9,104,273 (+)NCBICelera
Cytogenetic Map7q11NCBI
OR1I1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,082,211 - 15,092,970 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,082,211 - 15,092,970 (+)EnsemblGRCh38hg38GRCh38
GRCh371915,193,022 - 15,203,781 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,058,877 - 15,059,944 (+)NCBINCBI36Build 36hg18NCBI36
Build 341915,058,876 - 15,059,944NCBI
Celera1915,093,586 - 15,094,653 (+)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,765,566 - 14,766,633 (+)NCBIHuRef
CHM1_11915,197,371 - 15,198,438 (+)NCBICHM1_1
T2T-CHM13v2.01915,207,150 - 15,217,911 (+)NCBIT2T-CHM13v2.0
Or1i2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,447,503 - 78,453,908 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,446,837 - 78,453,908 (-)EnsemblGRCm39 Ensembl
GRCm381078,611,669 - 78,618,074 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,611,003 - 78,618,074 (-)EnsemblGRCm38mm10GRCm38
MGSCv371078,074,414 - 78,080,819 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361078,014,827 - 78,015,768 (-)NCBIMGSCv36mm8
Celera1079,633,878 - 79,640,283 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
LOC102012872
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554958,171,204 - 8,172,145 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554958,171,204 - 8,172,145 (-)NCBIChiLan1.0ChiLan1.0
LOC134729652
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,998,913 - 19,999,953 (+)NCBINHGRI_mPanPan1-v2
OR1I1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12047,037,917 - 47,038,873 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2047,037,917 - 47,146,610 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,888,653 - 46,889,609 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,530,991 - 47,531,947 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12046,762,423 - 46,763,379 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02047,181,614 - 47,182,570 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,452,759 - 47,453,715 (-)NCBIUU_Cfam_GSD_1.0
LOC101977308
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,818,354 - 205,819,322 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365965,367,493 - 5,368,434 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365965,367,493 - 5,368,693 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100523537
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,470,357 - 62,471,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1262,470,108 - 62,471,575 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2262,031,244 - 62,032,482 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103234061
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,682,193 - 13,683,939 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,682,583 - 13,683,647 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660745,844,972 - 5,846,239 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101705676
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,175,915 - 2,176,856 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249012,175,915 - 2,177,027 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Or1i2
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:22
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000009615
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 1
Below cutoff 2 1 3 1 1 5 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000009615   ⟹   ENSRNOP00000009615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl710,980,344 - 10,987,036 (+)Ensembl
Rnor_6.0 Ensembl713,996,966 - 13,997,907 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102702   ⟹   ENSRNOP00000091753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl710,984,634 - 10,987,036 (+)Ensembl
RefSeq Acc Id: NM_001000418   ⟹   NP_001000418
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,636,515 - 11,637,456 (+)NCBI
mRatBN7.2710,985,938 - 10,986,879 (+)NCBI
Rnor_6.0713,996,966 - 13,997,907 (+)NCBI
Rnor_5.0714,153,449 - 14,154,390 (+)NCBI
RGSC_v3.4712,543,995 - 12,544,936 (+)RGD
Celera79,103,332 - 9,104,273 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000418 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89448 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009615.5
  ENSRNOP00000091753.1
Reference Protein Sequences
RefSeq Acc Id: NP_001000418   ⟸   NM_001000418
- UniProtKB: D3ZZN7 (UniProtKB/TrEMBL),   A6K928 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000009615   ⟸   ENSRNOT00000009615
RefSeq Acc Id: ENSRNOP00000091753   ⟸   ENSRNOT00000102702
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZN7-F1-model_v2 AlphaFold D3ZZN7 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334246 AgrOrtholog
BioCyc Gene G2FUF-34839 BioCyc
Ensembl Genes ENSRNOG00000007348 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009615.5 UniProtKB/TrEMBL
  ENSRNOT00000102702.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:299586 UniProtKB/TrEMBL
NCBI Gene 299586 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 1I1 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1i2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007348 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6GJ75_RAT UniProtKB/TrEMBL
  A6K928 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZN7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or1i2  olfactory receptor family 1 subfamily I member 2  Olr1087  olfactory receptor 1087  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1087  olfactory receptor 1087   Olr1087_predicted  olfactory receptor 1087 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1087_predicted  olfactory receptor 1087 (predicted)      Symbol and Name status set to approved 70820 APPROVED