Or14j1 (olfactory receptor family 14 subfamily J member 1) - Rat Genome Database

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Gene: Or14j1 (olfactory receptor family 14 subfamily J member 1) Rattus norvegicus
Analyze
Symbol: Or14j1
Name: olfactory receptor family 14 subfamily J member 1
RGD ID: 1333127
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR14J1 (olfactory receptor family 14 subfamily J member 1); INTERACTS WITH atrazine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1693; olfactory receptor gene Olr1693; olfactory receptor Olr1693; Olr1693
RGD Orthologs
Human
Mouse
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820694,951 - 695,913 (-)NCBIGRCr8
mRatBN7.220689,684 - 690,646 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20685,475 - 692,605 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx20705,251 - 706,213 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.020708,716 - 709,678 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020623,799 - 624,761 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.020830,485 - 831,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl20830,485 - 831,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.020814,959 - 815,921 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.420646,784 - 647,746 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.120646,783 - 647,746 (-)NCBI
Celera201,463,529 - 1,464,491 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
megacolon  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or14j1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820694,951 - 695,913 (-)NCBIGRCr8
mRatBN7.220689,684 - 690,646 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20685,475 - 692,605 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx20705,251 - 706,213 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.020708,716 - 709,678 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020623,799 - 624,761 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.020830,485 - 831,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl20830,485 - 831,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.020814,959 - 815,921 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.420646,784 - 647,746 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.120646,783 - 647,746 (-)NCBI
Celera201,463,529 - 1,464,491 (-)NCBICelera
Cytogenetic Map20p12NCBI
OR14J1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,301,701 - 29,313,017 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,301,701 - 29,313,017 (+)EnsemblGRCh38hg38GRCh38
GRCh37629,269,478 - 29,280,794 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,382,446 - 29,383,411 (+)NCBINCBI36Build 36hg18NCBI36
Build 34629,382,445 - 29,383,411NCBI
Celera630,880,644 - 30,881,609 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,082,076 - 29,083,041 (+)NCBIHuRef
CHM1_1629,276,729 - 29,277,694 (+)NCBICHM1_1
T2T-CHM13v2.0629,176,465 - 29,187,793 (+)NCBIT2T-CHM13v2.0
Or14j1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391738,145,802 - 38,146,919 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1738,143,840 - 38,149,381 (+)EnsemblGRCm39 Ensembl
GRCm381737,834,911 - 37,836,028 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,832,949 - 37,838,490 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,971,856 - 37,972,973 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361737,443,054 - 37,444,016 (+)NCBIMGSCv36mm8
Celera1741,274,402 - 41,275,519 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
LOC100970983
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2543,934,315 - 43,945,610 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1639,898,673 - 39,909,976 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,124,922 - 29,126,027 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,783,067 - 29,784,172 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl629,783,126 - 29,784,091 (+)Ensemblpanpan1.1panPan2
OR14J1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13526,143,651 - 26,144,616 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3526,143,651 - 26,144,616 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3525,954,903 - 25,955,868 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03526,448,330 - 26,449,295 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3526,448,330 - 26,449,295 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13526,103,742 - 26,104,707 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03526,161,971 - 26,162,936 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,633,094 - 27,634,059 (+)NCBIUU_Cfam_GSD_1.0
LOC103221890
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11743,256,772 - 43,261,237 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1743,257,284 - 43,258,246 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604428,976,538 - 28,977,642 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101726258
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624756111,415 - 112,377 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624756111,415 - 112,465 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Or14j1
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000000976
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system exocrine system hepatobiliary system nervous system reproductive system
High
Medium
Low 1
Below cutoff 1 1 1 1 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000976   ⟹   ENSRNOP00000000976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl20830,485 - 831,447 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099203   ⟹   ENSRNOP00000083520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20685,475 - 692,605 (-)Ensembl
RefSeq Acc Id: NM_001000557   ⟹   NP_001000557
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr820694,951 - 695,913 (-)NCBI
mRatBN7.220689,684 - 690,646 (-)NCBI
Rnor_6.020830,485 - 831,447 (-)NCBI
Rnor_5.020814,959 - 815,921 (-)NCBI
RGSC_v3.420646,784 - 647,746 (-)RGD
Celera201,463,529 - 1,464,491 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000557 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84647 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000083520
  ENSRNOP00000083520.1
Reference Protein Sequences
RefSeq Acc Id: NP_001000557   ⟸   NM_001000557
- UniProtKB: D4ACX4 (UniProtKB/TrEMBL),   A6KR42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000000976   ⟸   ENSRNOT00000000976
RefSeq Acc Id: ENSRNOP00000083520   ⟸   ENSRNOT00000099203
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ACX4-F1-model_v2 AlphaFold D4ACX4 1-320 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333127 AgrOrtholog
BioCyc Gene G2FUF-5066 BioCyc
Ensembl Genes ENSRNOG00000000749 Ensembl
  ENSRNOG00000066890 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000099203 ENTREZGENE
  ENSRNOT00000099203.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:365523 UniProtKB/TrEMBL
NCBI Gene 365523 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 14J1 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or14j1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000749 RatGTEx
  ENSRNOG00000066890 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6KR42 ENTREZGENE, UniProtKB/TrEMBL
  D4ACX4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or14j1  olfactory receptor family 14 subfamily J member 1  Olr1693  olfactory receptor 1693  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1693  olfactory receptor 1693   Olr1693_predicted  olfactory receptor 1693 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1693_predicted  olfactory receptor 1693 (predicted)      Symbol and Name status set to approved 70820 APPROVED