Rngtt (RNA guanylyltransferase and 5'-phosphatase) - Rat Genome Database

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Gene: Rngtt (RNA guanylyltransferase and 5'-phosphatase) Rattus norvegicus
Analyze
Symbol: Rngtt
Name: RNA guanylyltransferase and 5'-phosphatase
RGD ID: 1311410
Description: Predicted to enable inorganic triphosphate phosphatase activity and mRNA guanylyltransferase activity. Predicted to be involved in 7-methylguanosine mRNA capping. Predicted to be located in nucleus. Orthologous to human RNGTT (RNA guanylyltransferase and 5'-phosphatase); PARTICIPATES IN 5'-end pre-mRNA capping pathway; RNA polymerase II transcription elongation pathway; mRNA decay pathway; INTERACTS WITH bisphenol A; gentamycin; indole-3-methanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313131; mRNA-capping enzyme
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8552,503,335 - 52,709,604 (+)NCBIGRCr8
mRatBN7.2547,706,929 - 47,913,297 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,706,799 - 47,913,295 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,857,742 - 50,071,279 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0551,456,933 - 51,670,474 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0551,400,292 - 51,606,537 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0548,561,325 - 48,779,214 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl548,561,339 - 48,779,207 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0553,143,335 - 53,362,344 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4549,605,150 - 49,811,502 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1549,605,435 - 49,809,750 (+)NCBI
Celera546,464,963 - 46,671,822 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cap-binding complex (CBC). Gonatopoulos-Pournatzis T and Cowling VH, Biochem J. 2014 Jan 15;457(2):231-42. doi: 10.1042/BJ20131214.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9473487   PMID:12477932   PMID:21636784  


Genomics

Comparative Map Data
Rngtt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8552,503,335 - 52,709,604 (+)NCBIGRCr8
mRatBN7.2547,706,929 - 47,913,297 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,706,799 - 47,913,295 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,857,742 - 50,071,279 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0551,456,933 - 51,670,474 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0551,400,292 - 51,606,537 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0548,561,325 - 48,779,214 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl548,561,339 - 48,779,207 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0553,143,335 - 53,362,344 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4549,605,150 - 49,811,502 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1549,605,435 - 49,809,750 (+)NCBI
Celera546,464,963 - 46,671,822 (+)NCBICelera
Cytogenetic Map5q21NCBI
RNGTT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38688,609,897 - 88,963,618 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl688,609,897 - 88,963,618 (-)EnsemblGRCh38hg38GRCh38
GRCh37689,319,616 - 89,673,337 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36689,376,708 - 89,730,067 (-)NCBINCBI36Build 36hg18NCBI36
Build 34689,376,717 - 89,730,023NCBI
Celera689,737,906 - 90,091,236 (-)NCBICelera
Cytogenetic Map6q15NCBI
HuRef686,535,387 - 86,889,057 (-)NCBIHuRef
CHM1_1689,417,753 - 89,771,218 (-)NCBICHM1_1
T2T-CHM13v2.0689,818,328 - 90,172,178 (-)NCBIT2T-CHM13v2.0
Rngtt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39433,310,300 - 33,502,610 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl433,310,311 - 33,502,614 (+)EnsemblGRCm39 Ensembl
GRCm38433,310,300 - 33,502,614 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl433,310,311 - 33,502,614 (+)EnsemblGRCm38mm10GRCm38
MGSCv37433,397,286 - 33,589,585 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36433,639,043 - 33,831,223 (+)NCBIMGSCv36mm8
Celera433,062,022 - 33,255,229 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.78NCBI
Rngtt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541115,486,303 - 15,766,864 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541115,486,532 - 15,766,880 (-)NCBIChiLan1.0ChiLan1.0
RNGTT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25108,695,586 - 109,049,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16106,585,758 - 106,950,049 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0686,490,725 - 86,841,421 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1689,761,712 - 90,118,184 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl689,761,712 - 90,118,184 (-)Ensemblpanpan1.1panPan2
RNGTT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11247,944,600 - 48,306,789 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1247,946,561 - 48,275,969 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1247,751,588 - 48,113,809 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01248,749,397 - 49,112,463 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1248,749,395 - 49,081,061 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11248,046,574 - 48,400,361 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01247,968,381 - 48,330,213 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01248,160,025 - 48,522,394 (-)NCBIUU_Cfam_GSD_1.0
Rngtt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494683,065,010 - 83,284,319 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365103,186,506 - 3,406,159 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365103,186,552 - 3,405,862 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNGTT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl156,852,866 - 57,061,972 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1156,852,864 - 57,061,985 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2163,571,851 - 63,750,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNGTT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11313,053,741 - 13,386,479 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1313,053,405 - 13,386,481 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040189,367,595 - 189,709,120 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rngtt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247995,225,264 - 5,554,168 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247995,225,293 - 5,553,957 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rngtt
1006 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:408
Count of miRNA genes:234
Interacting mature miRNAs:309
Transcripts:ENSRNOT00000010614
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat

Markers in Region
D5Rat52  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2547,845,483 - 47,845,673 (+)MAPPERmRatBN7.2
Rnor_6.0548,698,461 - 48,698,650NCBIRnor6.0
Rnor_5.0553,278,879 - 53,279,068UniSTSRnor5.0
RGSC_v3.4549,743,681 - 49,743,871RGDRGSC3.4
RGSC_v3.4549,743,682 - 49,743,871UniSTSRGSC3.4
RGSC_v3.1549,743,861 - 49,744,050RGD
Celera546,604,035 - 46,604,224UniSTS
RH 3.4 Map5262.39RGD
RH 3.4 Map5262.39UniSTS
RH 2.0 Map5290.5RGD
FHH x ACI Map528.07RGD
Cytogenetic Map5q21UniSTS
D5Rat4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2547,869,062 - 47,869,213 (+)MAPPERmRatBN7.2
Rnor_6.0548,722,038 - 48,722,188NCBIRnor6.0
Rnor_5.0553,302,456 - 53,302,606UniSTSRnor5.0
RGSC_v3.4549,767,271 - 49,767,421UniSTSRGSC3.4
RGSC_v3.4549,767,270 - 49,767,421RGDRGSC3.4
RGSC_v3.1549,767,450 - 49,767,600RGD
Celera546,627,612 - 46,627,764UniSTS
RH 3.4 Map5254.2RGD
RH 3.4 Map5254.2UniSTS
RH 2.0 Map5284.4RGD
SHRSP x BN Map531.7299RGD
FHH x ACI Map528.07RGD
Cytogenetic Map5q21UniSTS
D5Rat133  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2547,797,856 - 47,798,053 (+)MAPPERmRatBN7.2
Rnor_6.0548,652,724 - 48,652,920NCBIRnor6.0
Rnor_5.0553,233,142 - 53,233,338UniSTSRnor5.0
RGSC_v3.4549,696,057 - 49,696,253UniSTSRGSC3.4
Celera546,555,923 - 46,556,119UniSTS
SHRSP x BN Map531.7499UniSTS
SHRSP x BN Map531.7499RGD
Cytogenetic Map5q21UniSTS
BF386630  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2547,713,404 - 47,713,554 (+)MAPPERmRatBN7.2
Rnor_6.0548,567,816 - 48,567,965NCBIRnor6.0
Rnor_5.0553,149,212 - 53,149,361UniSTSRnor5.0
RGSC_v3.4549,611,602 - 49,611,751UniSTSRGSC3.4
Celera546,471,330 - 46,471,479UniSTS
RH 3.4 Map5245.6UniSTS
Cytogenetic Map5q21UniSTS
BE116192  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2547,826,341 - 47,826,554 (+)MAPPERmRatBN7.2
Rnor_6.0548,680,098 - 48,680,310NCBIRnor6.0
Rnor_5.0553,260,516 - 53,260,728UniSTSRnor5.0
RGSC_v3.4549,724,514 - 49,724,726UniSTSRGSC3.4
Celera546,584,895 - 46,585,107UniSTS
RH 3.4 Map5251.9UniSTS
Cytogenetic Map5q21UniSTS
AU048798  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0553,173,142 - 53,173,290UniSTSRnor5.0
Rnor_5.0686,703,412 - 86,704,981UniSTSRnor5.0
RGSC_v3.4676,673,062 - 76,674,650UniSTSRGSC3.4
RGSC_v3.4549,636,076 - 49,636,224UniSTSRGSC3.4
Celera546,495,943 - 46,496,091UniSTS
Cytogenetic Map5q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 34 18 18 18 74 23 37 11
Low 17 23 23 1 23 8 11 12 4 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_592456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC168990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000010614   ⟹   ENSRNOP00000010614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl547,707,011 - 47,913,295 (+)Ensembl
Rnor_6.0 Ensembl548,561,339 - 48,779,207 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091827   ⟹   ENSRNOP00000074574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl547,707,011 - 47,913,288 (+)Ensembl
Rnor_6.0 Ensembl548,561,339 - 48,779,207 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095052   ⟹   ENSRNOP00000082250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl547,706,799 - 47,913,295 (+)Ensembl
RefSeq Acc Id: NM_001107923   ⟹   NP_001101393
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,503,335 - 52,709,604 (+)NCBI
mRatBN7.2547,707,011 - 47,913,295 (+)NCBI
Rnor_6.0548,561,339 - 48,779,214 (+)NCBI
Rnor_5.0553,143,335 - 53,362,344 (+)NCBI
RGSC_v3.4549,605,150 - 49,811,502 (+)RGD
Celera546,464,963 - 46,671,822 (+)RGD
Sequence:
RefSeq Acc Id: XM_039109823   ⟹   XP_038965751
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,515,972 - 52,709,604 (+)NCBI
mRatBN7.2547,707,166 - 47,913,297 (+)NCBI
RefSeq Acc Id: XM_039109824   ⟹   XP_038965752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,503,377 - 52,709,604 (+)NCBI
mRatBN7.2547,706,936 - 47,913,297 (+)NCBI
RefSeq Acc Id: XM_039109825   ⟹   XP_038965753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,503,371 - 52,709,604 (+)NCBI
mRatBN7.2547,706,935 - 47,913,297 (+)NCBI
RefSeq Acc Id: XM_039109826   ⟹   XP_038965754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,503,376 - 52,642,311 (+)NCBI
mRatBN7.2547,706,937 - 47,845,972 (+)NCBI
RefSeq Acc Id: XM_039109827   ⟹   XP_038965755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,503,376 - 52,575,518 (+)NCBI
mRatBN7.2547,706,940 - 47,779,208 (+)NCBI
RefSeq Acc Id: XM_063287586   ⟹   XP_063143656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,503,376 - 52,661,230 (+)NCBI
RefSeq Acc Id: XM_063287587   ⟹   XP_063143657
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,503,376 - 52,706,016 (+)NCBI
RefSeq Acc Id: XM_063287588   ⟹   XP_063143658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,503,376 - 52,575,383 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001101393   ⟸   NM_001107923
- UniProtKB: D3ZH30 (UniProtKB/TrEMBL),   A6IIL7 (UniProtKB/TrEMBL),   B5DFA8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010614   ⟸   ENSRNOT00000010614
RefSeq Acc Id: ENSRNOP00000074574   ⟸   ENSRNOT00000091827
RefSeq Acc Id: XP_038965753   ⟸   XM_039109825
- Peptide Label: isoform X3
- UniProtKB: B5DFA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965752   ⟸   XM_039109824
- Peptide Label: isoform X2
- UniProtKB: B5DFA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965754   ⟸   XM_039109826
- Peptide Label: isoform X5
- UniProtKB: B5DFA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965755   ⟸   XM_039109827
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038965751   ⟸   XM_039109823
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZTT0 (UniProtKB/TrEMBL),   B5DFA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000082250   ⟸   ENSRNOT00000095052
RefSeq Acc Id: XP_063143657   ⟸   XM_063287587
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063143656   ⟸   XM_063287586
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063143658   ⟸   XM_063287588
- Peptide Label: isoform X7
Protein Domains
Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZH30-F1-model_v2 AlphaFold D3ZH30 1-597 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693617
Promoter ID:EPDNEW_R4140
Type:multiple initiation site
Name:Rngtt_1
Description:RNA guanylyltransferase and 5'-phosphatase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0548,561,317 - 48,561,377EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311410 AgrOrtholog
BioCyc Gene G2FUF-41688 BioCyc
BioCyc Pathway PWY-7375 [mRNA capping I] BioCyc
BioCyc Pathway Image PWY-7375 BioCyc
Ensembl Genes ENSRNOG00000007867 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010614 ENTREZGENE
  ENSRNOT00000010614.6 UniProtKB/TrEMBL
  ENSRNOT00000091827.2 UniProtKB/TrEMBL
  ENSRNOT00000095052.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
  3.30.1490.430 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
  DNA ligase/mRNA capping enzyme UniProtKB/TrEMBL
InterPro Dual-sp/Tyr_phosphatase UniProtKB/TrEMBL
  Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  mRNA_cap_enz_bifunc UniProtKB/TrEMBL
  mRNA_cap_enzyme UniProtKB/TrEMBL
  mRNA_cap_enzyme_C UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL_dom UniProtKB/TrEMBL
KEGG Report rno:313131 UniProtKB/TrEMBL
NCBI Gene 313131 ENTREZGENE
PANTHER MRNA-CAPPING ENZYME UniProtKB/TrEMBL
  MRNA-CAPPING ENZYME UniProtKB/TrEMBL
Pfam DSPc UniProtKB/TrEMBL
  mRNA_cap_C UniProtKB/TrEMBL
  mRNA_cap_enzyme UniProtKB/TrEMBL
PhenoGen Rngtt PhenoGen
PIRSF mRNA_capping_HCE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007867 RatGTEx
Superfamily-SCOP DNA ligase/mRNA capping enzyme, catalytic domain UniProtKB/TrEMBL
  Nucleic_acid_OB UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A8I5ZTT0 ENTREZGENE, UniProtKB/TrEMBL
  A6IIL6_RAT UniProtKB/TrEMBL
  A6IIL7 ENTREZGENE, UniProtKB/TrEMBL
  B5DFA8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZH30 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Rngtt  RNA guanylyltransferase and 5'-phosphatase   Rngtt_predicted  RNA guanylyltransferase and 5'-phosphatase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rngtt_predicted  RNA guanylyltransferase and 5'-phosphatase (predicted)      Symbol and Name status set to approved 70820 APPROVED