Rngtt (RNA guanylyltransferase and 5'-phosphatase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Rngtt (RNA guanylyltransferase and 5'-phosphatase) Ictidomys tridecemlineatus
Analyze
Symbol: Rngtt
Name: RNA guanylyltransferase and 5'-phosphatase
RGD ID: 12652674
Description: ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); GTP binding (inferred); INVOLVED IN 7-methylguanosine mRNA capping (inferred); nucleobase-containing compound metabolic process (inferred); RNA processing (inferred); PARTICIPATES IN 5'-end pre-mRNA capping pathway; RNA polymerase II transcription elongation pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mRNA-capping enzyme; RNA guanylyltransferase and 5'-phosphatase, transcript variant X1; RNA guanylyltransferase and 5'-phosphatase, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494683,065,010 - 83,284,319 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365103,186,506 - 3,406,159 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365103,186,552 - 3,405,862 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rngtt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494683,065,010 - 83,284,319 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365103,186,506 - 3,406,159 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365103,186,552 - 3,405,862 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNGTT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38688,609,897 - 88,963,618 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl688,609,897 - 88,963,618 (-)EnsemblGRCh38hg38GRCh38
GRCh37689,319,616 - 89,673,337 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36689,376,708 - 89,730,067 (-)NCBINCBI36Build 36hg18NCBI36
Build 34689,376,717 - 89,730,023NCBI
Celera689,737,906 - 90,091,236 (-)NCBICelera
Cytogenetic Map6q15NCBI
HuRef686,535,387 - 86,889,057 (-)NCBIHuRef
CHM1_1689,417,753 - 89,771,218 (-)NCBICHM1_1
T2T-CHM13v2.0689,818,328 - 90,172,178 (-)NCBIT2T-CHM13v2.0
Rngtt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39433,310,300 - 33,502,610 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl433,310,311 - 33,502,614 (+)EnsemblGRCm39 Ensembl
GRCm38433,310,300 - 33,502,614 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl433,310,311 - 33,502,614 (+)EnsemblGRCm38mm10GRCm38
MGSCv37433,397,286 - 33,589,585 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36433,639,043 - 33,831,223 (+)NCBIMGSCv36mm8
Celera433,062,022 - 33,255,229 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.78NCBI
Rngtt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8552,503,335 - 52,709,604 (+)NCBIGRCr8
mRatBN7.2547,706,929 - 47,913,297 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,706,799 - 47,913,295 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,857,742 - 50,071,279 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0551,456,933 - 51,670,474 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0551,400,292 - 51,606,537 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0548,561,325 - 48,779,214 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl548,561,339 - 48,779,207 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0553,143,335 - 53,362,344 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4549,605,150 - 49,811,502 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1549,605,435 - 49,809,750 (+)NCBI
Celera546,464,963 - 46,671,822 (+)NCBICelera
Cytogenetic Map5q21NCBI
Rngtt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541115,486,303 - 15,766,864 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541115,486,532 - 15,766,880 (-)NCBIChiLan1.0ChiLan1.0
RNGTT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25108,695,586 - 109,049,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16106,585,758 - 106,950,049 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0686,490,725 - 86,841,421 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1689,761,712 - 90,118,184 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl689,761,712 - 90,118,184 (-)Ensemblpanpan1.1panPan2
RNGTT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11247,944,600 - 48,306,789 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1247,946,561 - 48,275,969 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1247,751,588 - 48,113,809 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01248,749,397 - 49,112,463 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1248,749,395 - 49,081,061 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11248,046,574 - 48,400,361 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01247,968,381 - 48,330,213 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01248,160,025 - 48,522,394 (-)NCBIUU_Cfam_GSD_1.0
RNGTT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl156,852,866 - 57,061,972 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1156,852,864 - 57,061,985 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2163,571,851 - 63,750,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNGTT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11313,053,741 - 13,386,479 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1313,053,405 - 13,386,481 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040189,367,595 - 189,709,120 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rngtt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247995,225,264 - 5,554,168 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247995,225,293 - 5,553,957 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000007151   ⟹   ENSSTOP00000006391
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365103,186,506 - 3,406,159 (+)Ensembl
RefSeq Acc Id: XM_005324717   ⟹   XP_005324774
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494683,065,010 - 83,284,319 (-)NCBI
SpeTri2.0NW_0049365103,186,554 - 3,405,862 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005324774 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000006391.3
GenBank Protein KAG3289914 (Get FASTA)   NCBI Sequence Viewer  
  KAG3289915 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005324774   ⟸   XM_005324717
- UniProtKB: I3M970 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000006391   ⟸   ENSSTOT00000007151
Protein Domains
Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000007145 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007151.3 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
  3.30.1490.430 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
  DNA ligase/mRNA capping enzyme UniProtKB/TrEMBL
InterPro Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  mRNA_cap_enz_bifunc UniProtKB/TrEMBL
  mRNA_cap_enzyme_adenylation UniProtKB/TrEMBL
  mRNA_cap_enzyme_C UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL_dom UniProtKB/TrEMBL
NCBI Gene Rngtt ENTREZGENE
PANTHER MRNA-CAPPING ENZYME UniProtKB/TrEMBL
  MRNA-CAPPING ENZYME UniProtKB/TrEMBL
Pfam DSPc UniProtKB/TrEMBL
  mRNA_cap_C UniProtKB/TrEMBL
  mRNA_cap_enzyme UniProtKB/TrEMBL
PIRSF mRNA_capping_HCE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
Superfamily-SCOP DNA ligase/mRNA capping enzyme, catalytic domain UniProtKB/TrEMBL
  SSF50249 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt I3M970 ENTREZGENE, UniProtKB/TrEMBL