Setd3 (SET domain containing 3, actin N3(tau)-histidine methyltransferase) - Rat Genome Database

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Gene: Setd3 (SET domain containing 3, actin N3(tau)-histidine methyltransferase) Rattus norvegicus
Analyze
Symbol: Setd3
Name: SET domain containing 3, actin N3(tau)-histidine methyltransferase (Ensembl:SET domain containing 3, actin histidine methyltransferase)
RGD ID: 1309550
Description: Enables protein-L-histidine N-tele-methyltransferase activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and regulation of uterine smooth muscle contraction. Predicted to act upstream of or within positive regulation of muscle cell differentiation. Predicted to be located in cytoplasm. Predicted to be part of chromatin. Orthologous to human SETD3 (SET domain containing 3, actin N3(tau)-histidine methyltransferase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actin-histidine N-methyltransferase; histone-lysine N-methyltransferase setd3; histone-lysine N-methyltransferase setd3-like; LOC100910833; LOC299295; protein-L-histidine N-tele-methyltransferase; RGD1309550; SET domain containing 3; SET domain containing 3, actin histidine methyltransferase; SET domain-containing protein 3; similar to hypothetical protein D12Ertd771e
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Setd3-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86132,787,478 - 132,854,421 (-)NCBIGRCr8
mRatBN7.26127,023,058 - 127,090,020 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,023,058 - 127,090,008 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6127,147,450 - 127,214,376 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,442,494 - 127,509,420 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06126,800,688 - 126,867,637 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,023,128 - 132,090,072 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,023,945 - 132,075,875 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,193,508 - 141,260,420 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46132,479,553 - 132,546,414 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16132,455,160 - 132,552,700 (-)NCBI
Celera6124,582,489 - 124,649,275 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISO)
cytoplasm  (IEA,ISO,ISS)
nucleus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. SETD3 protein is the actin-specific histidine N-methyltransferase. Kwiatkowski S, etal., Elife. 2018 Dec 11;7. pii: 37921. doi: 10.7554/eLife.37921.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21832073   PMID:29950684   PMID:30626964   PMID:30785395   PMID:34218417  


Genomics

Comparative Map Data
Setd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86132,787,478 - 132,854,421 (-)NCBIGRCr8
mRatBN7.26127,023,058 - 127,090,020 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,023,058 - 127,090,008 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6127,147,450 - 127,214,376 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,442,494 - 127,509,420 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06126,800,688 - 126,867,637 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,023,128 - 132,090,072 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,023,945 - 132,075,875 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,193,508 - 141,260,420 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46132,479,553 - 132,546,414 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16132,455,160 - 132,552,700 (-)NCBI
Celera6124,582,489 - 124,649,275 (-)NCBICelera
Cytogenetic Map6q32NCBI
SETD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381499,397,748 - 99,486,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1499,397,748 - 99,480,889 (-)EnsemblGRCh38hg38GRCh38
GRCh371499,864,085 - 99,947,196 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361498,933,836 - 99,016,979 (-)NCBINCBI36Build 36hg18NCBI36
Celera1479,918,981 - 80,002,111 (-)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1480,047,465 - 80,130,640 (-)NCBIHuRef
CHM1_11499,801,849 - 99,884,990 (-)NCBICHM1_1
T2T-CHM13v2.01493,629,309 - 93,718,026 (-)NCBIT2T-CHM13v2.0
Setd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912108,072,690 - 108,145,616 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12108,072,690 - 108,145,573 (-)EnsemblGRCm39 Ensembl
GRCm3812108,106,431 - 108,179,345 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12108,106,431 - 108,179,314 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712109,344,641 - 109,417,494 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612108,554,247 - 108,627,070 (-)NCBIMGSCv36mm8
Celera12109,343,892 - 109,402,354 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.23NCBI
Setd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543820,754,539 - 20,826,700 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543820,754,593 - 20,826,570 (-)NCBIChiLan1.0ChiLan1.0
SETD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215100,552,654 - 100,635,474 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11499,769,148 - 99,851,960 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01480,022,123 - 80,104,935 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11499,344,422 - 99,427,036 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1499,343,164 - 99,426,486 (-)Ensemblpanpan1.1panPan2
SETD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1867,821,394 - 67,899,814 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl867,821,968 - 67,886,557 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha867,344,686 - 67,424,084 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0868,108,090 - 68,187,690 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl868,108,102 - 68,187,606 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1867,769,231 - 67,848,727 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0867,835,703 - 67,915,160 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,232,725 - 68,312,327 (-)NCBIUU_Cfam_GSD_1.0
Setd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086406,814,451 - 6,872,970 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366043,209,360 - 3,267,937 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366043,209,498 - 3,268,030 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SETD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7120,412,545 - 120,486,686 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17120,412,545 - 120,486,687 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27127,972,348 - 128,046,483 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SETD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12477,346,119 - 77,435,978 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2477,345,205 - 77,435,896 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605364,486,997 - 64,572,516 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Setd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247344,393,188 - 4,469,224 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247344,392,627 - 4,468,961 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Setd3
99 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:430
Count of miRNA genes:228
Interacting mature miRNAs:272
Transcripts:ENSRNOT00000009120, ENSRNOT00000044312
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat

Markers in Region
RH128412  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,023,210 - 127,023,426 (+)MAPPERmRatBN7.2
Rnor_6.06132,023,281 - 132,023,496NCBIRnor6.0
Rnor_5.06141,193,661 - 141,193,876UniSTSRnor5.0
RGSC_v3.46132,479,706 - 132,479,921UniSTSRGSC3.4
Celera6124,582,642 - 124,582,857UniSTS
RH 3.4 Map6791.7UniSTS
Cytogenetic Map6q32UniSTS
D12Ertd771e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,023,106 - 127,023,376 (+)MAPPERmRatBN7.2
Rnor_6.06132,023,177 - 132,023,446NCBIRnor6.0
Rnor_5.06141,193,557 - 141,193,826UniSTSRnor5.0
RGSC_v3.46132,479,602 - 132,479,871UniSTSRGSC3.4
Celera6124,582,538 - 124,582,807UniSTS
Cytogenetic Map6q32UniSTS
RH140597  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,023,841 - 127,024,045 (+)MAPPERmRatBN7.2
Rnor_6.06132,023,912 - 132,024,115NCBIRnor6.0
Rnor_5.06141,194,292 - 141,194,495UniSTSRnor5.0
RGSC_v3.46132,480,337 - 132,480,540UniSTSRGSC3.4
Celera6124,583,273 - 124,583,476UniSTS
Cytogenetic Map6q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000009120   ⟹   ENSRNOP00000009121
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,023,075 - 127,090,008 (-)Ensembl
Rnor_6.0 Ensembl6132,023,945 - 132,075,875 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000057179   ⟹   ENSRNOP00000054006
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,023,058 - 127,089,941 (-)Ensembl
Rnor_6.0 Ensembl6131,602,413 - 131,648,661 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094185   ⟹   ENSRNOP00000084001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,023,058 - 127,072,479 (-)Ensembl
RefSeq Acc Id: NM_001346470   ⟹   NP_001333399
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,854,421 (-)NCBI
mRatBN7.26127,023,058 - 127,090,008 (-)NCBI
RefSeq Acc Id: XM_063261778   ⟹   XP_063117848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,837,292 (-)NCBI
RefSeq Acc Id: XM_063261779   ⟹   XP_063117849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,840,235 (-)NCBI
RefSeq Acc Id: XM_063261780   ⟹   XP_063117850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,840,137 (-)NCBI
RefSeq Acc Id: XM_063261781   ⟹   XP_063117851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86132,787,478 - 132,840,175 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000009121   ⟸   ENSRNOT00000009120
RefSeq Acc Id: NP_001333399   ⟸   NM_001346470
- UniProtKB: Q5FWY6 (UniProtKB/Swiss-Prot),   G3V6U9 (UniProtKB/TrEMBL),   A6KBF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000054006   ⟸   ENSRNOT00000057179
RefSeq Acc Id: ENSRNOP00000084001   ⟸   ENSRNOT00000094185
RefSeq Acc Id: XP_063117849   ⟸   XM_063261779
- Peptide Label: isoform X2
- UniProtKB: A6KBF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117851   ⟸   XM_063261781
- Peptide Label: isoform X2
- UniProtKB: A6KBF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117850   ⟸   XM_063261780
- Peptide Label: isoform X2
- UniProtKB: A6KBF4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117848   ⟸   XM_063261778
- Peptide Label: isoform X1
- UniProtKB: D4A7S1 (UniProtKB/TrEMBL)
Protein Domains
SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A7S1-F1-model_v2 AlphaFold D4A7S1 1-381 view protein structure
AF-G3V6U9-F1-model_v2 AlphaFold G3V6U9 1-596 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309550 AgrOrtholog
BioCyc Gene G2FUF-36310 BioCyc
Ensembl Genes ENSRNOG00000006587 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00000046275 Ensembl
  ENSRNOG00055028714 UniProtKB/Swiss-Prot
  ENSRNOG00060019035 UniProtKB/Swiss-Prot
  ENSRNOG00065028495 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009120 ENTREZGENE
  ENSRNOT00000009120.9 UniProtKB/Swiss-Prot
  ENSRNOT00000057179.5 UniProtKB/TrEMBL
  ENSRNOT00000094185.1 UniProtKB/TrEMBL
  ENSRNOT00055049727 UniProtKB/Swiss-Prot
  ENSRNOT00060032966 UniProtKB/Swiss-Prot
  ENSRNOT00065049159 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.1420.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  set domain protein methyltransferase, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7311656 IMAGE-MGC_LOAD
InterPro Rubisco_LSMT_subst-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rubisco_LSMT_subst-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SET_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SETD3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SETD3_SET UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:299295 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105804 IMAGE-MGC_LOAD
NCBI Gene 299295 ENTREZGENE
PANTHER ACTIN-HISTIDINE N-METHYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Rubis-subs-bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SET UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Setd3 PhenoGen
PROSITE SAM_MT43_SETD3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SET UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006587 RatGTEx
  ENSRNOG00000046275 RatGTEx
  ENSRNOG00055028714 RatGTEx
  ENSRNOG00060019035 RatGTEx
  ENSRNOG00065028495 RatGTEx
Superfamily-SCOP SSF81822 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82199 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A126_RAT UniProtKB/TrEMBL
  A6KBF2 ENTREZGENE, UniProtKB/TrEMBL
  A6KBF4 ENTREZGENE, UniProtKB/TrEMBL
  D4A7S1 ENTREZGENE, UniProtKB/TrEMBL
  G3V6U9 ENTREZGENE
  Q5FWY6 ENTREZGENE
  SETD3_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q5FWY6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-09 Setd3  SET domain containing 3, actin N3(tau)-histidine methyltransferase  Setd3  SET domain containing 3, actin histidine methyltransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Setd3  SET domain containing 3, actin histidine methyltransferase  LOC100910833  histone-lysine N-methyltransferase setd3-like  Data merged from RGD:6496142 737654 PROVISIONAL
2019-01-04 Setd3  SET domain containing 3, actin histidine methyltransferase  Setd3  SET domain containing 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100910833  histone-lysine N-methyltransferase setd3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-26 Setd3  SET domain containing 3  RGD1309550  similar to hypothetical protein D12Ertd771e  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1309550  similar to hypothetical protein D12Ertd771e  RGD1309550_predicted  similar to hypothetical protein D12Ertd771e (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309550_predicted  similar to hypothetical protein D12Ertd771e (predicted)  LOC299295_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC299295_predicted  similar to hypothetical protein D12Ertd771e (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL