Ipo5 (importin 5) - Rat Genome Database

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Gene: Ipo5 (importin 5) Rattus norvegicus
Analyze
Symbol: Ipo5
Name: importin 5
RGD ID: 1308715
Description: Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in several processes, including cytoplasmic pattern recognition receptor signaling pathway; positive regulation of protein import into nucleus; and protein import into nucleus. Predicted to be located in Golgi apparatus; cytosol; and nucleus. Predicted to be active in cytoplasm and nucleus. Orthologous to human IPO5 (importin 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: importin-5; karyopherin (importin) beta 3; Kpnb3; LOC306182; RAN binding protein 5; Ranbp5; similar to RAN binding protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,397,626 - 104,447,985 (+)NCBIGRCr8
mRatBN7.21597,990,755 - 98,041,074 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,005,299 - 98,041,126 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.015106,243,110 - 106,293,326 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,257,650 - 106,292,112 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015109,639,020 - 109,689,209 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415105,944,155 - 106,021,407 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115105,983,354 - 106,037,884 (+)NCBI
Celera1596,799,493 - 96,849,477 (+)NCBICelera
Cytogenetic Map15q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-methoxyethanol  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acrolein  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
coumarin  (ISO)
decabromodiphenyl ether  (EXP)
deguelin  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenpyroximate  (ISO)
fenvalerate  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
ketoconazole  (ISO)
lovastatin  (ISO)
mercury dichloride  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
miconazole  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tebufenpyrad  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (IEA,ISO)
Golgi apparatus  (IEA,ISO)
nuclear membrane  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9687515   PMID:17143267   PMID:18504258   PMID:19946888   PMID:22681889   PMID:22730302  


Genomics

Comparative Map Data
Ipo5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,397,626 - 104,447,985 (+)NCBIGRCr8
mRatBN7.21597,990,755 - 98,041,074 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,005,299 - 98,041,126 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.015106,243,110 - 106,293,326 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,257,650 - 106,292,112 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015109,639,020 - 109,689,209 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415105,944,155 - 106,021,407 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115105,983,354 - 106,037,884 (+)NCBI
Celera1596,799,493 - 96,849,477 (+)NCBICelera
Cytogenetic Map15q24NCBI
IPO5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381397,953,675 - 98,024,296 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1397,953,658 - 98,024,296 (+)EnsemblGRCh38hg38GRCh38
GRCh371398,605,929 - 98,676,550 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361397,403,930 - 97,474,551 (+)NCBINCBI36Build 36hg18NCBI36
Celera1379,453,341 - 79,523,964 (+)NCBICelera
Cytogenetic Map13q32.2NCBI
HuRef1379,203,817 - 79,274,125 (+)NCBIHuRef
CHM1_11398,576,302 - 98,646,937 (+)NCBICHM1_1
T2T-CHM13v2.01397,160,508 - 97,231,138 (+)NCBIT2T-CHM13v2.0
Ipo5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914121,134,271 - 121,185,451 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14121,148,636 - 121,185,411 (+)EnsemblGRCm39 Ensembl
GRCm3814120,896,840 - 120,948,046 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14120,911,224 - 120,947,999 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714121,310,416 - 121,347,268 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614120,046,431 - 120,083,179 (+)NCBIMGSCv36mm8
Celera14119,467,218 - 119,497,933 (+)NCBICelera
Cytogenetic Map14E4- E5NCBI
cM Map1464.81NCBI
Ipo5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540412,416,755 - 12,459,452 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540412,416,755 - 12,480,281 (-)NCBIChiLan1.0ChiLan1.0
IPO5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21499,471,672 - 99,541,033 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11398,140,454 - 98,209,817 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01379,115,320 - 79,185,598 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11398,295,472 - 98,336,707 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1398,294,766 - 98,336,700 (+)Ensemblpanpan1.1panPan2
IPO5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12248,126,053 - 48,182,897 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2248,136,242 - 48,180,495 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2247,906,269 - 47,965,065 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02248,566,642 - 48,625,469 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2248,566,671 - 48,625,439 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12248,215,943 - 48,274,722 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02248,249,947 - 48,308,738 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02248,285,886 - 48,344,697 (+)NCBIUU_Cfam_GSD_1.0
Ipo5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945183,675,492 - 183,720,213 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647212,229,922 - 12,271,964 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647212,231,970 - 12,271,639 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IPO5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1167,004,109 - 67,060,551 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11167,019,299 - 67,059,375 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21174,138,179 - 74,173,295 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IPO5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1376,644,113 - 76,690,718 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl376,644,131 - 76,692,146 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604633,103,550 - 33,150,436 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ipo5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479312,969,459 - 13,004,139 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479312,971,397 - 13,004,126 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ipo5
146 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:596
Count of miRNA genes:199
Interacting mature miRNAs:238
Transcripts:ENSRNOT00000014859, ENSRNOT00000072538
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)158226252098288169Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)158226252098288169Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat

Markers in Region
RH130384  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21812,037,710 - 12,037,891 (-)MAPPERmRatBN7.2
mRatBN7.21598,039,233 - 98,039,872 (+)MAPPERmRatBN7.2
Rnor_6.015106,291,486 - 106,292,124NCBIRnor6.0
Rnor_6.01815,440,311 - 15,440,491NCBIRnor6.0
Rnor_5.01815,219,000 - 15,219,180UniSTSRnor5.0
Rnor_5.015109,687,385 - 109,688,023UniSTSRnor5.0
RGSC_v3.41812,501,618 - 12,501,798UniSTSRGSC3.4
RGSC_v3.415106,020,163 - 106,020,801UniSTSRGSC3.4
Celera1596,847,637 - 96,848,275UniSTS
Celera1812,045,603 - 12,045,783UniSTS
Cytogenetic Map15q24UniSTS
RH133768  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,040,273 - 98,040,459 (+)MAPPERmRatBN7.2
Rnor_6.015106,292,526 - 106,292,711NCBIRnor6.0
Rnor_5.015109,688,425 - 109,688,610UniSTSRnor5.0
RGSC_v3.415106,021,203 - 106,021,388UniSTSRGSC3.4
Celera1596,848,677 - 96,848,862UniSTS
Celera1593,556,470 - 93,556,654UniSTS
RH 3.4 Map15644.7UniSTS
Cytogenetic Map15q24UniSTS
RH140893  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,040,776 - 98,040,976 (+)MAPPERmRatBN7.2
Rnor_6.015106,293,029 - 106,293,228NCBIRnor6.0
Rnor_5.015109,688,928 - 109,689,127UniSTSRnor5.0
RGSC_v3.415106,021,706 - 106,021,905UniSTSRGSC3.4
Celera1596,849,180 - 96,849,379UniSTS
RH 3.4 Map15687.7UniSTS
Cytogenetic Map15q24UniSTS
C76941  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21812,037,856 - 12,038,058 (-)MAPPERmRatBN7.2
mRatBN7.21598,037,637 - 98,039,268 (+)MAPPERmRatBN7.2
Rnor_6.015106,289,890 - 106,291,520NCBIRnor6.0
Rnor_6.01815,440,144 - 15,440,345NCBIRnor6.0
Rnor_5.01815,218,833 - 15,219,034UniSTSRnor5.0
Rnor_5.015109,685,789 - 109,687,419UniSTSRnor5.0
RGSC_v3.41812,501,764 - 12,501,965UniSTSRGSC3.4
RGSC_v3.415106,018,567 - 106,020,197UniSTSRGSC3.4
Celera1596,846,041 - 96,847,671UniSTS
Celera1812,045,749 - 12,045,950UniSTS
Cytogenetic Map15q24UniSTS
RH126066  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,039,208 - 98,039,909 (+)MAPPERmRatBN7.2
Rnor_6.015106,291,461 - 106,292,161NCBIRnor6.0
Rnor_5.015109,687,360 - 109,688,060UniSTSRnor5.0
RGSC_v3.415106,020,138 - 106,020,838UniSTSRGSC3.4
Celera1596,847,612 - 96,848,312UniSTS
Cytogenetic Map15q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 5
Medium 3 43 57 41 19 41 8 11 74 35 36 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000014859   ⟹   ENSRNOP00000014859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1598,005,299 - 98,041,126 (+)Ensembl
Rnor_6.0 Ensembl15106,257,650 - 106,292,112 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000072538   ⟹   ENSRNOP00000066802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1598,005,789 - 98,041,126 (+)Ensembl
Rnor_6.0 Ensembl15106,257,650 - 106,292,112 (+)Ensembl
RefSeq Acc Id: NM_001427143   ⟹   NP_001414072
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,412,248 - 104,447,985 (+)NCBI
RefSeq Acc Id: XM_017599929   ⟹   XP_017455418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,397,626 - 104,447,356 (+)NCBI
mRatBN7.21597,990,755 - 98,041,074 (+)NCBI
Rnor_6.015106,243,110 - 106,292,172 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039093991   ⟹   XP_038949919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,397,626 - 104,447,356 (+)NCBI
mRatBN7.21597,990,755 - 98,041,074 (+)NCBI
RefSeq Acc Id: XM_063274353   ⟹   XP_063130423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,397,690 - 104,447,356 (+)NCBI
RefSeq Acc Id: XM_063274354   ⟹   XP_063130424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,398,040 - 104,447,356 (+)NCBI
RefSeq Acc Id: XM_063274355   ⟹   XP_063130425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,412,664 - 104,447,356 (+)NCBI
RefSeq Acc Id: XM_224534   ⟹   XP_224534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,397,690 - 104,447,356 (+)NCBI
mRatBN7.21597,991,169 - 98,041,074 (+)NCBI
Rnor_6.015106,243,145 - 106,293,326 (+)NCBI
Rnor_5.015109,639,020 - 109,689,209 (+)NCBI
RGSC_v3.415105,944,155 - 106,021,407 (+)RGD
Sequence:
RefSeq Acc Id: XP_224534   ⟸   XM_224534
- Peptide Label: isoform X2
- UniProtKB: D4A781 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455418   ⟸   XM_017599929
- Peptide Label: isoform X2
- UniProtKB: D4A781 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000066802   ⟸   ENSRNOT00000072538
RefSeq Acc Id: ENSRNOP00000014859   ⟸   ENSRNOT00000014859
RefSeq Acc Id: XP_038949919   ⟸   XM_039093991
- Peptide Label: isoform X2
- UniProtKB: D4A781 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130423   ⟸   XM_063274353
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130424   ⟸   XM_063274354
- Peptide Label: isoform X2
- UniProtKB: D4A781 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414072   ⟸   NM_001427143
- UniProtKB: D4A781 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130425   ⟸   XM_063274355
- Peptide Label: isoform X3
- UniProtKB: M0RB74 (UniProtKB/TrEMBL)
Protein Domains
Importin N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A781-F1-model_v2 AlphaFold D4A781 1-1097 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699888
Promoter ID:EPDNEW_R10401
Type:initiation region
Name:Ipo5_1
Description:importin 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.015106,257,629 - 106,257,689EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308715 AgrOrtholog
BioCyc Gene G2FUF-12384 BioCyc
Ensembl Genes ENSRNOG00000010989 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014859.9 UniProtKB/TrEMBL
  ENSRNOT00000072538.3 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  HEAT UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  Importin_beta UniProtKB/TrEMBL
  Importin_rep_4 UniProtKB/TrEMBL
  Importin_rep_5 UniProtKB/TrEMBL
  Importin_rep_6 UniProtKB/TrEMBL
  TOG UniProtKB/TrEMBL
KEGG Report rno:306182 UniProtKB/TrEMBL
NCBI Gene 306182 ENTREZGENE
PANTHER IMPORTIN-5 UniProtKB/TrEMBL
  PTHR10527 UniProtKB/TrEMBL
Pfam HEAT UniProtKB/TrEMBL
  HEAT_EZ UniProtKB/TrEMBL
  Importin_rep_4 UniProtKB/TrEMBL
  Importin_rep_5 UniProtKB/TrEMBL
  Importin_rep_6 UniProtKB/TrEMBL
PhenoGen Ipo5 PhenoGen
PROSITE IMPORTIN_B_NT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010989 RatGTEx
SMART TOG UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt D4A781 ENTREZGENE, UniProtKB/TrEMBL
  M0RB74 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Ipo5  importin 5  LOC685210  similar to RAN binding protein 5  Data merged from RGD:1596486 1643240 APPROVED
2008-05-15 Ipo5  importin 5  Ranbp5  RAN binding protein 5   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ranbp5  RAN binding protein 5   Ranbp5_predicted  RAN binding protein 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC685210  similar to RAN binding protein 5      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Ranbp5_predicted  RAN binding protein 5 (predicted)  Kpnb3_predicted  karyopherin (importin) beta 3 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Kpnb3_predicted  karyopherin (importin) beta 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED