Adar (adenosine deaminase, RNA-specific) - Rat Genome Database

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Gene: Adar (adenosine deaminase, RNA-specific) Rattus norvegicus
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Symbol: Adar
Name: adenosine deaminase, RNA-specific
RGD ID: 71099
Description: Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to virus; and nucleocytoplasmic transport. Predicted to act upstream of or within several processes, including hematopoietic stem cell homeostasis; hemopoiesis; and regulatory ncRNA-mediated gene silencing. Located in nuclear speck. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; Human papillomavirus infectious disease; dyschromatosis symmetrica hereditaria; and liver cirrhosis. Orthologous to human ADAR (adenosine deaminase RNA specific); PARTICIPATES IN microRNA pathway; influenza A pathway; measles pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: adenosine deaminase RNA-specific; double-stranded RNA-specific adenosine deaminase; DRADA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,436,076 - 177,475,969 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2177,436,094 - 177,475,971 (+)EnsemblGRCr8
mRatBN7.22175,138,391 - 175,178,280 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,138,403 - 175,178,282 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2182,303,808 - 182,324,734 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,326,190 - 180,347,116 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,927,089 - 174,948,007 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,045,551 - 189,085,448 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,062,443 - 189,083,236 (+)Ensemblrn6Rnor6.0
Rnor_5.02208,468,426 - 208,506,275 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42181,935,246 - 181,956,039 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2169,097,840 - 169,118,615 (+)NCBICelera
RGSC_v3.12181,885,351 - 181,906,145 (+)NCBI
Cytogenetic Map2q34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-nonylphenol  (ISO)
4-tert-Octylphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
clofibrate  (ISO)
clotrimazole  (EXP)
crocidolite asbestos  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
flutamide  (EXP)
FR900359  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
inulin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
ozone  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
poly(I:C)  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
triptonide  (ISO)
tungsten  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
mitochondrion  (ISO)
nuclear lumen  (IEA)
nuclear speck  (IDA)
nucleolus  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)
supraspliceosomal complex  (IEA,ISO,ISS)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ADAR1 overexpression is associated with cervical cancer progression and angiogenesis. Chen Y, etal., Diagn Pathol. 2017 Jan 21;12(1):12. doi: 10.1186/s13000-017-0600-0.
2. Dynamic association of RNA-editing enzymes with the nucleolus. Desterro JM, etal., J Cell Sci. 2003 May 1;116(Pt 9):1805-18.
3. Janus effects of ADAR1 on CVB3-induced viral myocarditis at different infection stages. Dong N, etal., Int J Cardiol. 2016 Nov 15;223:898-905. doi: 10.1016/j.ijcard.2016.08.315. Epub 2016 Aug 22.
4. Integrative role of vitamin D related and Interleukin-28B genes polymorphism in predicting treatment outcomes of Chronic Hepatitis C. El-Derany MO, etal., BMC Gastroenterol. 2016 Feb 24;16:19. doi: 10.1186/s12876-016-0440-5.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. A-to-I editing of microRNAs: regulating the regulators? Gommans WM Semin Cell Dev Biol. 2012 May;23(3):251-7. doi: 10.1016/j.semcdb.2011.09.018. Epub 2011 Oct 5.
7. Gene-gene and gene-environment interactions in interferon therapy for chronic hepatitis C. Lin E, etal., Pharmacogenomics. 2007 Oct;8(10):1327-35. doi: 10.2217/14622416.8.10.1327.
8. ADAR1 polymorphisms are related to severity of liver fibrosis in HIV/HCV-coinfected patients. Medrano LM, etal., Sci Rep. 2017 Oct 10;7(1):12918. doi: 10.1038/s41598-017-12885-4.
9. Gene Data Set MGD Curation, June 12, 2002
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Mutations of the RNA-specific adenosine deaminase gene (DSRAD) are involved in dyschromatosis symmetrica hereditaria. Miyamura Y, etal., Am J Hum Genet. 2003 Sep;73(3):693-9. Epub 2003 Aug 11.
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. O'Connell MA, etal., Mol Cell Biol 1995 Mar;15(3):1389-97.
14. Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer. Okugawa Y, etal., J Transl Med. 2018 Dec 18;16(1):366. doi: 10.1186/s12967-018-1740-z.
15. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. ADAR1 affects HCV infection by modulating innate immune response. Pujantell M, etal., Antiviral Res. 2018 Aug;156:116-127. doi: 10.1016/j.antiviral.2018.05.012. Epub 2018 Jun 12.
18. ADAR1 function affects HPV replication and is associated to recurrent human papillomavirus-induced dysplasia in HIV coinfected individuals. Pujantell M, etal., Sci Rep. 2019 Dec 27;9(1):19848. doi: 10.1038/s41598-019-56422-x.
19. GOA pipeline RGD automated data pipeline
20. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
22. Comprehensive gene review and curation RGD comprehensive gene curation
23. Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature. Rice GI, etal., Nat Genet. 2012 Nov;44(11):1243-8. doi: 10.1038/ng.2414. Epub 2012 Sep 23.
24. Editing of AMPA and serotonin 2C receptors in individual central neurons, controlling wakefulness. Sergeeva OA, etal., Cell Mol Neurobiol. 2007 Aug;27(5):669-80.
25. Tissue selectivity of interferon-stimulated gene expression in mice infected with Dam(+) versus Dam(-) Salmonella enterica serovar Typhimurium strains. Shtrichman R, etal., Infect Immun. 2002 Oct;70(10):5579-88. doi: 10.1128/iai.70.10.5579-5588.2002.
26. Mutation analysis of the ADAR1 gene in dyschromatosis symmetrica hereditaria and genetic differentiation from both dyschromatosis universalis hereditaria and acropigmentatio reticularis. Suzuki N, etal., J Invest Dermatol. 2005 Jun;124(6):1186-92.
27. Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene. Wang Q, etal., J Biol Chem. 2004 Feb 6;279(6):4952-61. Epub 2003 Nov 12.
28. Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis. Wang Q, etal., Science 2000 Dec 1;290(5497):1765-8.
29. Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial. Welzel TM, etal., Hepatology. 2009 Jun;49(6):1847-58. doi: 10.1002/hep.22877.
30. A functional polymorphism in ADAR1 gene affects HBsAg seroclearance both spontaneously and interferon induced. Wu X, etal., Liver Int. 2014 Nov;34(10):1560-5. doi: 10.1111/liv.12444. Epub 2014 Jan 16.
31. Adenosine deaminase that acts on RNA 1 p150 in alveolar macrophage is involved in LPS-induced lung injury. Wu Y, etal., Shock. 2009 Apr;31(4):410-15. doi: 10.1097/SHK.0b013e31817c1068.
32. ADAR1p150 Forms a Complex with Dicer to Promote miRNA-222 Activity and Regulate PTEN Expression in CVB3-Induced Viral Myocarditis. Zhang X, etal., Int J Mol Sci. 2019 Jan 18;20(2). pii: ijms20020407. doi: 10.3390/ijms20020407.
Additional References at PubMed
PMID:9020165   PMID:12954622   PMID:14615479   PMID:15556947   PMID:15858013   PMID:16475990   PMID:17369310   PMID:18362360   PMID:19060901   PMID:19124606   PMID:19651874   PMID:19805087  
PMID:19946888   PMID:21173229   PMID:21289159   PMID:22658674   PMID:22681889   PMID:23123729   PMID:23209284   PMID:23622242   PMID:24882218   PMID:28355180   PMID:31505169   PMID:34800366  


Genomics

Comparative Map Data
Adar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,436,076 - 177,475,969 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2177,436,094 - 177,475,971 (+)EnsemblGRCr8
mRatBN7.22175,138,391 - 175,178,280 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,138,403 - 175,178,282 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2182,303,808 - 182,324,734 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,326,190 - 180,347,116 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,927,089 - 174,948,007 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,045,551 - 189,085,448 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,062,443 - 189,083,236 (+)Ensemblrn6Rnor6.0
Rnor_5.02208,468,426 - 208,506,275 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42181,935,246 - 181,956,039 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2169,097,840 - 169,118,615 (+)NCBICelera
RGSC_v3.12181,885,351 - 181,906,145 (+)NCBI
Cytogenetic Map2q34NCBI
ADAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381154,582,057 - 154,627,997 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1154,581,695 - 154,628,013 (-)Ensemblhg38GRCh38
GRCh371154,554,533 - 154,600,473 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,821,157 - 152,867,061 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341151,367,612 - 151,393,742NCBI
Celera1127,626,167 - 127,672,093 (-)NCBICelera
Cytogenetic Map1q21.3ENTREZGENE
HuRef1125,917,984 - 125,963,676 (-)NCBIHuRef
CHM1_11155,950,933 - 155,996,946 (-)NCBICHM1_1
T2T-CHM13v2.01153,719,177 - 153,765,142 (-)NCBIT2T-CHM13v2.0
Adar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,622,321 - 89,660,756 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,622,329 - 89,660,753 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38389,714,469 - 89,753,455 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,715,022 - 89,753,446 (+)Ensemblmm10GRCm38
MGSCv37389,518,944 - 89,557,377 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36389,800,987 - 89,839,372 (+)NCBIMGSCv36mm8
Celera389,752,022 - 89,790,497 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.19NCBI
Adar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,078,319 - 1,106,938 (-)Ensembl
ChiLan1.0NW_0049555451,078,319 - 1,106,938 (-)NCBIChiLan1.0ChiLan1.0
ADAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2195,202,292 - 95,251,931 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,937,379 - 94,984,250 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01129,937,993 - 129,983,747 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,549,380 - 133,595,115 (-)NCBIPanPan1.1PanPan1.1panPan2
ADAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,762,021 - 42,785,192 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,748,136 - 42,782,999 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha742,237,226 - 42,275,953 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0742,632,040 - 42,655,201 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,616,310 - 42,655,189 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1742,411,330 - 42,434,458 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,449,549 - 42,488,308 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,733,156 - 42,771,908 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,150,541 - 25,177,944 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,183,079 - 4,203,435 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,183,016 - 4,208,341 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl495,154,357 - 95,197,304 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1495,154,230 - 95,197,308 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,980,303 - 104,023,300 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1209,194,611 - 9,241,102 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl209,219,937 - 9,241,329 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660388,533,486 - 8,579,871 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adar
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,812,448 - 2,839,693 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248852,783,058 - 2,839,688 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Adar
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1363,906,038 - 63,945,339 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Adar
1035 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:271
Count of miRNA genes:186
Interacting mature miRNAs:208
Transcripts:ENSRNOT00000028181
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2169358774214358774Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2138595962205135428Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
61457Niddm8Non-insulin dependent diabetes mellitus QTL 84.10.01blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2176840779178247591Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2124537199209621565Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2145807215220931416Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2122597372215234002Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085199723085Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2145807215190807215Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085199723085Rat
10043139Iddm55Insulin dependent diabetes mellitus QTL 553.10.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2150313808195313808Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085199723085Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2159440891205135267Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085199723085Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170652929215652929Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2159440891220931218Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2171994826205135428Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085178247591Rat
61473Bp19Blood pressure QTL 196.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837178247591Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2143565208188565208Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2154723085178247591Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085178247591Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2154723085199723085Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2139067258192287892Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2159440760195313808Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2144882354205135428Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1357991Ael2Aortic elastin QTL 24.20.000071aorta elastin amount (VT:0003905)aortic elastin2169227906214227906Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1578671Bmd10Bone mineral density QTL 105.4femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)2175931416220931416Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2139067258184067258Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085178247591Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2143746578205135428Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085178247591Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150096616195096616Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2154723085178247591Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2145306936212705578Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2147287892192287892Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150096616195096616Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837220008837Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2165453811210453811Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2163253030208253030Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
7488904Bp363Blood pressure QTL 3630.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2175279960178247591Rat

Markers in Region
AI710840  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,177,971 - 175,178,167 (+)MAPPERmRatBN7.2
Rnor_6.02189,085,140 - 189,085,335NCBIRnor6.0
Rnor_5.02208,507,991 - 208,508,186UniSTSRnor5.0
RGSC_v3.42181,957,943 - 181,958,138UniSTSRGSC3.4
Celera2169,120,519 - 169,120,714UniSTS
RH 3.4 Map21155.1UniSTS
Cytogenetic Map2q34UniSTS
AA964848  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,176,904 - 175,177,004 (+)MAPPERmRatBN7.2
Rnor_6.02189,084,073 - 189,084,172NCBIRnor6.0
Rnor_5.02208,506,924 - 208,507,023UniSTSRnor5.0
RGSC_v3.42181,956,876 - 181,956,975UniSTSRGSC3.4
Celera2169,119,452 - 169,119,551UniSTS
RH 3.4 Map21155.2UniSTS
Cytogenetic Map2q34UniSTS
UniSTS:479064  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,174,493 - 175,175,950 (+)MAPPERmRatBN7.2
Rnor_6.02189,081,662 - 189,083,118NCBIRnor6.0
Rnor_5.02208,504,513 - 208,505,969UniSTSRnor5.0
RGSC_v3.42181,954,465 - 181,955,921UniSTSRGSC3.4
Celera2169,117,041 - 169,118,497UniSTS
Cytogenetic Map2q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U18942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000028181   ⟹   ENSRNOP00000028181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2177,452,915 - 177,475,971 (+)Ensembl
mRatBN7.2 Ensembl2175,155,273 - 175,176,068 (+)Ensembl
Rnor_6.0 Ensembl2189,062,443 - 189,083,236 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093799   ⟹   ENSRNOP00000090863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2177,436,094 - 177,475,971 (+)Ensembl
mRatBN7.2 Ensembl2175,138,403 - 175,178,282 (+)Ensembl
RefSeq Acc Id: NM_031006   ⟹   NP_112268
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,452,964 - 177,473,757 (+)NCBI
mRatBN7.22175,155,273 - 175,176,068 (+)NCBI
Rnor_6.02189,062,443 - 189,083,236 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
RGSC_v3.42181,935,246 - 181,956,039 (+)RGD
Celera2169,097,840 - 169,118,615 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232774   ⟹   XP_006232836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,125 - 177,475,969 (+)NCBI
mRatBN7.22175,138,392 - 175,178,280 (+)NCBI
Rnor_6.02189,045,551 - 189,085,448 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232775   ⟹   XP_006232837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,106 - 177,475,969 (+)NCBI
mRatBN7.22175,138,391 - 175,178,280 (+)NCBI
Rnor_6.02189,045,551 - 189,084,195 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232776   ⟹   XP_006232838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,443,191 - 177,475,969 (+)NCBI
mRatBN7.22175,154,800 - 175,178,280 (+)NCBI
Rnor_6.02189,059,261 - 189,084,195 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232778   ⟹   XP_006232840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,118 - 177,475,969 (+)NCBI
mRatBN7.22175,138,423 - 175,178,280 (+)NCBI
Rnor_6.02189,045,593 - 189,084,195 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103210   ⟹   XP_038959138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,106 - 177,475,969 (+)NCBI
mRatBN7.22175,138,391 - 175,178,280 (+)NCBI
RefSeq Acc Id: XM_063282619   ⟹   XP_063138689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,443,193 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282620   ⟹   XP_063138690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,443,187 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282621   ⟹   XP_063138691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,104 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282622   ⟹   XP_063138692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,124 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282623   ⟹   XP_063138693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,076 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282624   ⟹   XP_063138694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,459,258 - 177,475,969 (+)NCBI
RefSeq Acc Id: NP_112268   ⟸   NM_031006
- UniProtKB: P55266 (UniProtKB/Swiss-Prot),   A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232837   ⟸   XM_006232775
- Peptide Label: isoform X2
- UniProtKB: A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232836   ⟸   XM_006232774
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AEC1 (UniProtKB/TrEMBL),   A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232840   ⟸   XM_006232778
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006232838   ⟸   XM_006232776
- Peptide Label: isoform X3
- UniProtKB: A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028181   ⟸   ENSRNOT00000028181
RefSeq Acc Id: XP_038959138   ⟸   XM_039103210
- Peptide Label: isoform X4
- UniProtKB: A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000090863   ⟸   ENSRNOT00000093799
RefSeq Acc Id: XP_063138693   ⟸   XM_063282623
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063138691   ⟸   XM_063282621
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063138692   ⟸   XM_063282622
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063138690   ⟸   XM_063282620
- Peptide Label: isoform X6
- UniProtKB: A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138689   ⟸   XM_063282619
- Peptide Label: isoform X5
- UniProtKB: A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138694   ⟸   XM_063282624
- Peptide Label: isoform X10
- UniProtKB: A6J6H3 (UniProtKB/TrEMBL)
Protein Domains
A to I editase   DRBM   Z-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P55266-F1-model_v2 AlphaFold P55266 1-1175 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691481
Promoter ID:EPDNEW_R2006
Type:multiple initiation site
Name:Adar_1
Description:adenosine deaminase, RNA-specific
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02189,062,421 - 189,062,481EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71099 AgrOrtholog
BioCyc Gene G2FUF-52400 BioCyc
Ensembl Genes ENSRNOG00000020744 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000028181 ENTREZGENE
  ENSRNOT00000093799 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
  3.30.160.20 UniProtKB/Swiss-Prot
InterPro A_deamin UniProtKB/Swiss-Prot
  ADAR1_DSRM_1 UniProtKB/Swiss-Prot
  ADAR1_DSRM_3 UniProtKB/Swiss-Prot
  dsRBD_dom UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot
  Zalpha_dom UniProtKB/Swiss-Prot
KEGG Report rno:81635 UniProtKB/Swiss-Prot
NCBI Gene 81635 ENTREZGENE
PANTHER DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE UniProtKB/Swiss-Prot
  EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN UniProtKB/Swiss-Prot
Pfam A_deamin UniProtKB/Swiss-Prot
  dsrm UniProtKB/Swiss-Prot
  z-alpha UniProtKB/Swiss-Prot
PhenoGen Adar PhenoGen
PROSITE A_DEAMIN_EDITASE UniProtKB/Swiss-Prot
  DRADA_REPEAT UniProtKB/Swiss-Prot
  DS_RBD UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020744 RatGTEx
SMART ADEAMc UniProtKB/Swiss-Prot
  DSRM UniProtKB/Swiss-Prot
  Zalpha UniProtKB/Swiss-Prot
Superfamily-SCOP dsRNA-binding domain-like UniProtKB/Swiss-Prot
  SSF46785 UniProtKB/Swiss-Prot
UniProt A0A8I6AEC1 ENTREZGENE, UniProtKB/TrEMBL
  A6J6H2 ENTREZGENE, UniProtKB/TrEMBL
  A6J6H3 ENTREZGENE, UniProtKB/TrEMBL
  DSRAD_RAT UniProtKB/Swiss-Prot
  G3V8T3 ENTREZGENE, UniProtKB/TrEMBL
  P55266 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Adar  adenosine deaminase, RNA-specific      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function modifies more frequently the adenosines in AU-rich regions 724707
gene_function modifies viral RNA genomes and may be responsible for hypermutation of certain negative-stranded viruses 724707