Osgin1 (oxidative stress induced growth inhibitor 1) - Rat Genome Database

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Gene: Osgin1 (oxidative stress induced growth inhibitor 1) Rattus norvegicus
Analyze
Symbol: Osgin1
Name: oxidative stress induced growth inhibitor 1
RGD ID: 620679
Description: Predicted to enable growth factor activity. Predicted to be involved in negative regulation of cell growth. Orthologous to human OSGIN1 (oxidative stress induced growth inhibitor 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Okl38; oxidative stress-induced growth inhibitor 1; pregnancy-induced growth inhibitor
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,380,336 - 64,409,165 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1964,401,173 - 64,409,162 (+)EnsemblGRCr8
mRatBN7.21947,471,750 - 47,500,517 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,492,171 - 47,500,516 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1954,279,628 - 54,294,893 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01954,960,419 - 54,975,701 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,173,810 - 57,189,105 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,056,808 - 52,085,491 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,077,109 - 52,085,496 (+)Ensemblrn6Rnor6.0
Rnor_5.01962,818,232 - 62,834,031 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41949,675,215 - 49,690,479 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1946,744,527 - 46,759,791 (+)NCBICelera
RGSC_v3.11949,680,095 - 49,695,359 (+)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butoxyethanol  (ISO)
2-hydroxyethyl methacrylate  (ISO)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
Aflatoxin G1  (ISO)
Aflatoxin G2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
azathioprine  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP,ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (EXP,ISO)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chloroprene  (ISO)
chloroquine  (EXP)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corn oil  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diethyl malate  (ISO)
diethyl maleate  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
enniatin  (ISO)
epoxiconazole  (ISO)
fenofibrate  (EXP)
fenthion  (ISO)
fentin chloride  (EXP)
ferric oxide  (EXP)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
fulvestrant  (ISO)
furan  (EXP,ISO)
genistein  (ISO)
gentamycin  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
GW 4064  (ISO)
hydrogen peroxide  (ISO)
ifosfamide  (ISO)
inulin  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
LY294002  (ISO)
menadione  (ISO)
mercury dichloride  (EXP)
metformin  (EXP)
methamphetamine  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
naphthalene  (ISO)
nevirapine  (ISO)
nitrofen  (EXP)
ochratoxin A  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
oxycodone  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
propiconazole  (ISO)
quercetin  (EXP)
quinolin-8-ol  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 203580  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sotorasib  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
trametinib  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
midbody  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning and characterization of a novel pregnancy-induced growth inhibitor in mammary gland. Huynh H, etal., Endocrinology 2001 Aug;142(8):3607-15.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1302223   PMID:12477932   PMID:15217983  


Genomics

Comparative Map Data
Osgin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,380,336 - 64,409,165 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1964,401,173 - 64,409,162 (+)EnsemblGRCr8
mRatBN7.21947,471,750 - 47,500,517 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,492,171 - 47,500,516 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1954,279,628 - 54,294,893 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01954,960,419 - 54,975,701 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,173,810 - 57,189,105 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,056,808 - 52,085,491 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,077,109 - 52,085,496 (+)Ensemblrn6Rnor6.0
Rnor_5.01962,818,232 - 62,834,031 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41949,675,215 - 49,690,479 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1946,744,527 - 46,759,791 (+)NCBICelera
RGSC_v3.11949,680,095 - 49,695,359 (+)NCBI
Cytogenetic Map19q12NCBI
OSGIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381683,953,240 - 83,966,332 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1683,931,311 - 83,966,333 (+)Ensemblhg38GRCh38
GRCh371683,986,845 - 83,999,937 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361682,540,173 - 82,557,438 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1668,283,632 - 68,302,337 (+)NCBICelera
Cytogenetic Map16q23.3NCBI
HuRef1669,737,904 - 69,751,578 (+)NCBIHuRef
CHM1_11685,398,355 - 85,411,465 (+)NCBICHM1_1
T2T-CHM13v2.01690,019,300 - 90,032,388 (+)NCBIT2T-CHM13v2.0
Osgin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,160,874 - 120,172,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8120,160,863 - 120,172,995 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388119,425,882 - 119,446,257 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,434,124 - 119,446,256 (+)Ensemblmm10GRCm38
MGSCv378121,961,062 - 121,970,156 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368122,323,139 - 122,332,233 (+)NCBIMGSCv36mm8
Celera8123,654,251 - 123,663,345 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map867.71NCBI
OSGIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21893,679,420 - 93,714,857 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11699,596,537 - 99,631,845 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01664,555,632 - 64,590,930 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11683,942,912 - 83,978,111 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1683,942,912 - 83,978,111 (+)EnsemblpanPan2panpan1.1
OSGIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1568,344,406 - 68,377,842 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha568,358,285 - 68,392,074 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0568,642,665 - 68,676,414 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl568,642,008 - 68,676,232 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1568,590,364 - 68,624,216 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0568,426,772 - 68,460,641 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0568,842,573 - 68,876,492 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Osgin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934928,050,244 - 28,075,053 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366413,803,767 - 3,813,041 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366413,803,799 - 3,812,995 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSGIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl64,642,764 - 4,653,487 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.164,642,762 - 4,656,113 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
OSGIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1569,365,072 - 69,378,319 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl569,365,096 - 69,378,319 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660476,409,526 - 6,422,520 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Osgin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247463,577,184 - 3,610,079 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Osgin1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11739,084,621 - 39,093,009 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:62
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000020225
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
D3Rat22  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21947,483,643 - 47,483,996 (+)MAPPERmRatBN7.2
Rnor_6.01952,068,621 - 52,068,973NCBIRnor6.0
Rnor_5.01962,817,161 - 62,817,513UniSTSRnor5.0
RGSC_v3.41949,673,571 - 49,674,008RGDRGSC3.4
RGSC_v3.41949,673,609 - 49,673,961UniSTSRGSC3.4
Celera1946,742,921 - 46,743,273UniSTS
RGSC_v3.11949,678,490 - 49,678,842RGD
RH 3.4 Map19650.9UniSTS
RH 3.4 Map19650.9RGD
RH 2.0 Map19676.2RGD
FHH x ACI Map360.54RGD
Cytogenetic Map19q12UniSTS
AU047953  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81964,400,269 - 64,400,403 (+)Marker Load Pipeline
mRatBN7.21947,491,621 - 47,491,755 (+)MAPPERmRatBN7.2
Rnor_6.01952,076,596 - 52,076,729NCBIRnor6.0
Rnor_5.01962,825,136 - 62,825,269UniSTSRnor5.0
RGSC_v3.41949,681,584 - 49,681,717UniSTSRGSC3.4
Celera1946,750,896 - 46,751,029UniSTS
Cytogenetic Map19q12UniSTS
AI236754  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21947,500,358 - 47,500,491 (+)MAPPERmRatBN7.2
Rnor_6.01952,085,333 - 52,085,465NCBIRnor6.0
Rnor_5.01962,833,873 - 62,834,005UniSTSRnor5.0
RGSC_v3.41949,690,321 - 49,690,453UniSTSRGSC3.4
Celera1946,759,633 - 46,759,765UniSTS
RH 3.4 Map19648.6UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 154 91 90 59 92 59 6 356 192 11 133 81 92 31 15 15

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001433950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF549441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF549442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY081218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC091111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000020225   ⟹   ENSRNOP00000020225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1964,401,173 - 64,409,162 (+)Ensembl
mRatBN7.2 Ensembl1947,492,171 - 47,500,514 (+)Ensembl
Rnor_6.0 Ensembl1952,077,109 - 52,085,490 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079240   ⟹   ENSRNOP00000072990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1947,495,826 - 47,500,516 (+)Ensembl
Rnor_6.0 Ensembl1952,077,501 - 52,085,496 (+)Ensembl
RefSeq Acc Id: NM_138504   ⟹   NP_612513
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,393,901 - 64,409,165 (+)NCBI
mRatBN7.21947,485,250 - 47,500,517 (+)NCBI
Rnor_6.01952,070,227 - 52,085,491 (+)NCBI
Rnor_5.01962,818,232 - 62,834,031 (+)NCBI
RGSC_v3.41949,675,215 - 49,690,479 (+)RGD
Celera1946,744,527 - 46,759,791 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255706   ⟹   XP_006255768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,336 - 64,409,165 (+)NCBI
mRatBN7.21947,471,750 - 47,500,517 (+)NCBI
Rnor_6.01952,056,808 - 52,085,491 (+)NCBI
Rnor_5.01962,818,232 - 62,834,031 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097443   ⟹   XP_038953371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
mRatBN7.21947,471,750 - 47,500,517 (+)NCBI
RefSeq Acc Id: XM_039097445   ⟹   XP_038953373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
mRatBN7.21947,471,750 - 47,500,517 (+)NCBI
RefSeq Acc Id: XM_039097446   ⟹   XP_038953374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
mRatBN7.21947,471,750 - 47,500,517 (+)NCBI
RefSeq Acc Id: XM_039097447   ⟹   XP_038953375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
mRatBN7.21947,471,750 - 47,500,517 (+)NCBI
RefSeq Acc Id: XM_063277754   ⟹   XP_063133824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277755   ⟹   XP_063133825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277756   ⟹   XP_063133826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277757   ⟹   XP_063133827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277758   ⟹   XP_063133828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,583 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277759   ⟹   XP_063133829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277760   ⟹   XP_063133830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277761   ⟹   XP_063133831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277762   ⟹   XP_063133832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,400 - 64,409,165 (+)NCBI
RefSeq Acc Id: XM_063277763   ⟹   XP_063133833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,380,532 - 64,409,165 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001420879 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420883 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420885 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420886 (Get FASTA)   NCBI Sequence Viewer  
  NP_612513 (Get FASTA)   NCBI Sequence Viewer  
  XP_006255768 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953371 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953373 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953374 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953375 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133824 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133825 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133826 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133827 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133828 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133829 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133830 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133831 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133832 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133833 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91111 (Get FASTA)   NCBI Sequence Viewer  
  AAL89808 (Get FASTA)   NCBI Sequence Viewer  
  AAN59895 (Get FASTA)   NCBI Sequence Viewer  
  AAN59896 (Get FASTA)   NCBI Sequence Viewer  
  EDL92665 (Get FASTA)   NCBI Sequence Viewer  
  EDL92666 (Get FASTA)   NCBI Sequence Viewer  
  EDL92667 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020225
  ENSRNOP00000020225.3
RefSeq Acc Id: NP_612513   ⟸   NM_138504
- UniProtKB: Q8R430 (UniProtKB/TrEMBL),   F7EN26 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255768   ⟸   XM_006255706
- Peptide Label: isoform X1
- UniProtKB: Q8R430 (UniProtKB/TrEMBL),   F7EN26 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072990   ⟸   ENSRNOT00000079240
Ensembl Acc Id: ENSRNOP00000020225   ⟸   ENSRNOT00000020225
RefSeq Acc Id: XP_038953373   ⟸   XM_039097445
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953374   ⟸   XM_039097446
- Peptide Label: isoform X1
- UniProtKB: Q8R430 (UniProtKB/TrEMBL),   F7EN26 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953371   ⟸   XM_039097443
- Peptide Label: isoform X1
- UniProtKB: Q8R430 (UniProtKB/TrEMBL),   F7EN26 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953375   ⟸   XM_039097447
- Peptide Label: isoform X1
- UniProtKB: Q8R430 (UniProtKB/TrEMBL),   F7EN26 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133824   ⟸   XM_063277754
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133832   ⟸   XM_063277762
- Peptide Label: isoform X1
- UniProtKB: F7EN26 (UniProtKB/TrEMBL),   Q8R430 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133830   ⟸   XM_063277760
- Peptide Label: isoform X1
- UniProtKB: F7EN26 (UniProtKB/TrEMBL),   Q8R430 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133825   ⟸   XM_063277755
- Peptide Label: isoform X1
- UniProtKB: F7EN26 (UniProtKB/TrEMBL),   Q8R430 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133829   ⟸   XM_063277759
- Peptide Label: isoform X1
- UniProtKB: F7EN26 (UniProtKB/TrEMBL),   Q8R430 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133826   ⟸   XM_063277756
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133827   ⟸   XM_063277757
- Peptide Label: isoform X1
- UniProtKB: F7EN26 (UniProtKB/TrEMBL),   Q8R430 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133831   ⟸   XM_063277761
- Peptide Label: isoform X1
- UniProtKB: F7EN26 (UniProtKB/TrEMBL),   Q8R430 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133833   ⟸   XM_063277763
- Peptide Label: isoform X1
- UniProtKB: F7EN26 (UniProtKB/TrEMBL),   Q8R430 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133828   ⟸   XM_063277758
- Peptide Label: isoform X1
- UniProtKB: F7EN26 (UniProtKB/TrEMBL),   Q8R430 (UniProtKB/TrEMBL),   A0A0G2K4C7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R430-F1-model_v2 AlphaFold Q8R430 1-478 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701179
Promoter ID:EPDNEW_R11701
Type:single initiation site
Name:Osgin1_1
Description:oxidative stress induced growth inhibitor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01952,077,154 - 52,077,214EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620679 AgrOrtholog
BioCyc Gene G2FUF-5518 BioCyc
Ensembl Genes ENSRNOG00000014948 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020225 ENTREZGENE
  ENSRNOT00000020225.7 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7106386 IMAGE-MGC_LOAD
InterPro FAD/NAD-bd_sf UniProtKB/TrEMBL
  OKL38_fam UniProtKB/TrEMBL
KEGG Report rno:171493 UniProtKB/TrEMBL
MGC_CLONE MGC:108541 IMAGE-MGC_LOAD
NCBI Gene 171493 ENTREZGENE
PANTHER PTHR15192 UniProtKB/TrEMBL
  PTHR15192:SF15 UniProtKB/TrEMBL
Pfam Pyr_redox_3 UniProtKB/TrEMBL
PhenoGen Osgin1 PhenoGen
RatGTEx ENSRNOG00000014948 RatGTEx
Superfamily-SCOP SSF51905 UniProtKB/TrEMBL
UniProt A0A0G2K4C7 ENTREZGENE
  F7EN26 ENTREZGENE, UniProtKB/TrEMBL
  Q8R430 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-22 Osgin1  oxidative stress induced growth inhibitor 1  Okl38  pregnancy-induced growth inhibitor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Okl38  pregnancy-induced growth inhibitor      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Okl38  pregnancy-induced growth inhibitor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression displays increased expression in mammary epithelial cells during pregnancy and lactation 1302223
gene_physical_interaction overexpression of the human homolog reduces tumor formation in dimethylbenz(A)anthracene (DMBA)-induced mammary tumors 1302223