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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620679
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Osgin1
Name: oxidative stress induced growth inhibitor 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Osgin1affects expressionEXP 6480464CTDbisphenol A affects the expression of OSGIN1 mRNAPMID:30903817
Osgin1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of OSGIN1 mRNAPMID:30816183 PMID:32145629 PMID:32528016
Osgin1increases expressionEXP 6480464CTDbisphenol A results in increased expression of OSGIN1 mRNAPMID:25181051
Osgin1affects expressionISOOSGIN1 (Homo sapiens)6480464CTDbisphenol A affects the expression of OSGIN1 mRNAPMID:20170705 PMID:30903817
Osgin1decreases methylationISOOsgin1 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of OSGIN1 promoterPMID:27312807
Osgin1increases expressionISOOsgin1 (Mus musculus)6480464CTDbisphenol A results in increased expression of OSGIN1 mRNAPMID:33221593 PMID:34585602
Osgin1increases expressionISOOSGIN1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of OSGIN1 mRNAPMID:29275510
Osgin1multiple interactionsISOOSGIN1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of OSGIN1 genePMID:31601247
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