Lfng (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Lfng (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) Rattus norvegicus
Analyze
Symbol: Lfng
Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGD ID: 620587
Description: Predicted to enable O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Predicted to be involved in lymphocyte differentiation; negative regulation of Notch signaling pathway involved in somitogenesis; and somitogenesis. Predicted to act upstream of or within several processes, including compartment pattern specification; positive regulation of Notch signaling pathway; and regulation of somitogenesis. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 3. Orthologous to human LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase); PARTICIPATES IN Notch signaling pathway; O-linked glycan biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; lunatic fringe gene homolog; lunatic fringe gene homolog (Drosophila); O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,144,474 - 19,152,951 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1219,124,662 - 19,152,918 (-)EnsemblGRCr8
mRatBN7.21214,030,551 - 14,038,996 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1214,018,333 - 14,039,008 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1214,839,113 - 14,847,134 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,462,384 - 15,470,633 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,489,324 - 14,497,345 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,117,767 - 16,126,211 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,118,634 - 16,126,953 (-)Ensemblrn6Rnor6.0
Rnor_5.01218,113,805 - 18,123,172 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41214,497,704 - 14,505,723 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1215,790,243 - 15,798,262 (-)NCBICelera
RGSC_v3.11214,527,632 - 14,535,651 (-)NCBI
Cytogenetic Map12q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
butylated hydroxyanisole  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
ethanol  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
lead diacetate  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methoxyacetic acid  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
pentanal  (ISO)
phenylmercury acetate  (ISO)
potassium chloride  (ISO)
progesterone  (ISO)
propanal  (ISO)
propionic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cell and molecular biology of Notch. Fiuza UM and Arias AM, J Endocrinol. 2007 Sep;194(3):459-74.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth. Mustonen T, etal., Dev Biol 2002 Aug 15;248(2):281-93.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10935626   PMID:12001066   PMID:15489334   PMID:15574878   PMID:15659488   PMID:16385447   PMID:18234727   PMID:19061953   PMID:19217325   PMID:19779553   PMID:23072809   PMID:24769233  
PMID:28089369  


Genomics

Comparative Map Data
Lfng
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,144,474 - 19,152,951 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1219,124,662 - 19,152,918 (-)EnsemblGRCr8
mRatBN7.21214,030,551 - 14,038,996 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1214,018,333 - 14,039,008 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1214,839,113 - 14,847,134 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,462,384 - 15,470,633 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,489,324 - 14,497,345 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,117,767 - 16,126,211 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,118,634 - 16,126,953 (-)Ensemblrn6Rnor6.0
Rnor_5.01218,113,805 - 18,123,172 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41214,497,704 - 14,505,723 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1215,790,243 - 15,798,262 (-)NCBICelera
RGSC_v3.11214,527,632 - 14,535,651 (-)NCBI
Cytogenetic Map12q11NCBI
LFNG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3872,512,529 - 2,529,177 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl72,512,529 - 2,529,177 (+)Ensemblhg38GRCh38
GRCh3772,552,163 - 2,568,811 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3672,526,005 - 2,535,337 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3472,330,737 - 2,341,302NCBI
Celera72,521,470 - 2,538,114 (+)NCBICelera
Cytogenetic Map7p22.3NCBI
HuRef72,469,979 - 2,486,577 (+)NCBIHuRef
CHM1_172,551,728 - 2,568,392 (+)NCBICHM1_1
T2T-CHM13v2.072,625,971 - 2,642,596 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v272,600,032 - 2,616,654 (+)NCBI
Lfng
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395140,593,096 - 140,601,300 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5140,593,075 - 140,601,300 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385140,607,341 - 140,615,545 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5140,607,320 - 140,615,545 (+)Ensemblmm10GRCm38
MGSCv375141,083,295 - 141,091,499 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365140,859,841 - 140,866,960 (+)NCBIMGSCv36mm8
Celera5137,667,846 - 137,675,959 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map579.15NCBI
Lfng
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546012,773,975 - 12,784,512 (-)Ensembl
ChiLan1.0NW_00495546012,773,975 - 12,784,512 (-)NCBIChiLan1.0ChiLan1.0
LFNG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v267,477,996 - 7,487,441 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1755,802,701 - 55,812,142 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v072,781,493 - 2,790,936 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.172,876,721 - 2,884,926 (+)NCBIPanPan1.1PanPan1.1panPan2
LFNG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1614,631,638 - 14,640,147 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl614,632,691 - 14,635,485 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha616,094,444 - 16,103,246 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0614,757,824 - 14,766,634 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl614,757,836 - 14,766,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1614,561,780 - 14,570,581 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0614,490,186 - 14,498,963 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0614,776,050 - 14,784,860 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lfng
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344142,760,468 - 142,768,231 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936823283,205 - 290,986 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936823283,207 - 290,970 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LFNG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl31,810,892 - 1,820,048 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.131,721,044 - 1,819,426 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.232,208,304 - 2,267,857 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LFNG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12819,084,527 - 19,092,305 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660902,679,194 - 2,686,982 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lfng
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474030,392,079 - 30,404,068 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474030,392,342 - 30,404,003 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lfng
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11612,589,628 - 12,598,066 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lfng
78 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:76
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000001682
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat

Markers in Region
AI236775  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81219,144,493 - 19,145,194 (+)Marker Load Pipeline
mRatBN7.21214,030,570 - 14,031,271 (+)MAPPERmRatBN7.2
Rnor_6.01216,117,787 - 16,118,487NCBIRnor6.0
Rnor_5.01218,113,612 - 18,114,289UniSTSRnor5.0
RGSC_v3.41214,497,062 - 14,497,999UniSTSRGSC3.4
Celera1215,789,852 - 15,790,538UniSTS
Cytogenetic Map12q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001682   ⟹   ENSRNOP00000001682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1219,131,324 - 19,152,918 (-)Ensembl
mRatBN7.2 Ensembl1214,018,333 - 14,039,008 (-)Ensembl
Rnor_6.0 Ensembl1216,118,634 - 16,126,953 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101623   ⟹   ENSRNOP00000086737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1219,144,900 - 19,152,918 (-)Ensembl
mRatBN7.2 Ensembl1214,030,551 - 14,039,008 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000131458   ⟹   ENSRNOP00000111620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1219,124,662 - 19,152,918 (-)Ensembl
RefSeq Acc Id: NM_133393   ⟹   NP_596884
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81219,144,899 - 19,152,918 (-)NCBI
mRatBN7.21214,030,976 - 14,038,996 (-)NCBI
Rnor_6.01216,118,192 - 16,126,211 (-)NCBI
Rnor_5.01218,113,805 - 18,123,172 (-)NCBI
RGSC_v3.41214,497,704 - 14,505,723 (-)RGD
Celera1215,790,243 - 15,798,262 (-)RGD
Sequence:
RefSeq Acc Id: XM_017598250   ⟹   XP_017453739
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81219,144,474 - 19,152,394 (-)NCBI
mRatBN7.21214,030,551 - 14,038,470 (-)NCBI
Rnor_6.01216,117,767 - 16,125,717 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063271024   ⟹   XP_063127094
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81219,145,755 - 19,152,951 (-)NCBI
Protein Sequences
Protein RefSeqs NP_596884 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453739 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127094 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH70933 (Get FASTA)   NCBI Sequence Viewer  
  BAB63256 (Get FASTA)   NCBI Sequence Viewer  
  EDL89727 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000086737
  ENSRNOP00000086737.1
GenBank Protein Q924T4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_596884   ⟸   NM_133393
- Peptide Label: precursor
- UniProtKB: Q924T4 (UniProtKB/Swiss-Prot),   A6K1R9 (UniProtKB/TrEMBL),   A0A8L2UHG7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453739   ⟸   XM_017598250
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000001682   ⟸   ENSRNOT00000001682
Ensembl Acc Id: ENSRNOP00000086737   ⟸   ENSRNOT00000101623
RefSeq Acc Id: XP_063127094   ⟸   XM_063271024
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000111620   ⟸   ENSRNOT00000131458
Protein Domains
Fringe-like glycosyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q924T4-F1-model_v2 AlphaFold Q924T4 1-378 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698453
Promoter ID:EPDNEW_R8978
Type:single initiation site
Name:Lfng_1
Description:LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01216,126,224 - 16,126,284EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620587 AgrOrtholog
BioCyc Gene G2FUF-19929 BioCyc
Ensembl Genes ENSRNOG00000001250 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000101623 ENTREZGENE
  ENSRNOT00000101623.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.550.50 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7097855 IMAGE-MGC_LOAD
InterPro Fringe UniProtKB/Swiss-Prot
  Fringe-like UniProtKB/Swiss-Prot
KEGG Report rno:170905 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91508 IMAGE-MGC_LOAD
NCBI Gene 170905 ENTREZGENE
PANTHER FRINGE-RELATED UniProtKB/Swiss-Prot
Pfam Fringe UniProtKB/Swiss-Prot
PhenoGen Lfng PhenoGen
PIRSF B-acetylgalactosaminyltfrase UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001250 RatGTEx
UniProt A0A8L2UHG7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M310_RAT UniProtKB/TrEMBL
  A6K1R9 ENTREZGENE, UniProtKB/TrEMBL
  LFNG_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-22 Lfng  LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase  Lfng  lunatic fringe gene homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Lfng  lunatic fringe gene homolog (Drosophila)      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Lfng  lunatic fringe gene homolog (Drosophila)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_process induces Hes1 expression in dental epithelium 727405