Cysltr2 (cysteinyl leukotriene receptor 2) - Rat Genome Database

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Gene: Cysltr2 (cysteinyl leukotriene receptor 2) Rattus norvegicus
Analyze
Symbol: Cysltr2
Name: cysteinyl leukotriene receptor 2
RGD ID: 619797
Description: Predicted to enable cysteinyl leukotriene receptor activity and galanin receptor activity. Involved in several processes, including cellular response to hypoxia; negative regulation of glial cell proliferation; and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in aspirin-induced respiratory disease and asthma. Orthologous to human CYSLTR2 (cysteinyl leukotriene receptor 2); PARTICIPATES IN endothelin signaling pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH ammonium chloride; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cyslt2; cysteinyl leukotriene CysLT2 receptor; RSBPT32
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81554,599,043 - 54,638,314 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1554,598,818 - 54,713,597 (-)EnsemblGRCr8
mRatBN7.21548,189,476 - 48,228,750 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1548,189,073 - 48,304,136 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1552,335,467 - 52,371,705 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01553,447,041 - 53,483,279 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01550,280,153 - 50,323,717 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01554,903,290 - 54,941,742 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1554,905,274 - 54,906,203 (-)Ensemblrn6Rnor6.0
Rnor_5.01558,626,639 - 58,627,568 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41553,647,500 - 53,648,429 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1547,842,400 - 47,878,749 (-)NCBICelera
RGSC_v3.11553,663,279 - 53,664,209 (-)NCBI
Cytogenetic Map15p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA,ISO)
plasma membrane  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice. Beller TC, etal., J Biol Chem. 2004 Oct 29;279(44):46129-34. Epub 2004 Aug 24.
2. Association between a polymorphism in cysteinyl leukotriene receptor 2 on chromosome 13q14 and atopic asthma. Fukai H, etal., Pharmacogenetics. 2004 Oct;14(10):683-90.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Activation of CysLT receptors induces astrocyte proliferation and death after oxygen-glucose deprivation. Huang XJ, etal., Glia. 2008 Jan 1;56(1):27-37.
5. Cysteinyl leukotriene receptors are expressed by tonsillar T cells of children with obstructive sleep apnea. Kaditis AG, etal., Chest. 2008 Aug;134(2):324-31. Epub 2008 May 19.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Mouse Genome Database (MGD) Mouse Genome Database (MGD)
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics. Park JS, etal., Pharmacogenet Genomics. 2005 Jul;15(7):483-92.
10. Expression of eicosanoid receptors subtypes and eosinophilic inflammation: implication on chronic rhinosinusitis. Perez-Novo CA, etal., Respir Res. 2006 May 12;7:75.
11. A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma. Pillai SG, etal., Pharmacogenetics. 2004 Sep;14(9):627-33.
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14. CysLT2 receptor-mediated AQP4 up-regulation is involved in ischemic-like injury through activation of ERK and p38 MAPK in rat astrocytes. Qi LL, etal., Life Sci. 2011 Jan 3;88(1-2):50-6. Epub 2010 Nov 3.
15. GOA pipeline RGD automated data pipeline
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Comprehensive gene review and curation RGD comprehensive gene curation
18. Involvement of leukotrienes in the pathogenesis of silica-induced pulmonary fibrosis in mice. Shimbori C, etal., Exp Lung Res. 2010 Jun;36(5):292-301.
19. Involvement of cysteinyl leukotriene receptors in angiogenesis in rat thoracic aortic rings. Xu L, etal., Pharmazie. 2010 Oct;65(10):750-4.
20. Expression of cysteinyl leukotriene receptor in brain tissues of rats with Streptococcus pneumoniae meningitis. Yu S, etal., Int J Clin Exp Pathol. 2019 Dec 1;12(12):4242-4252. eCollection 2019.
21. Cysteinyl leukotriene receptor 2 is spatiotemporally involved in neuron injury, astrocytosis and microgliosis after focal cerebral ischemia in rats. Zhao CZ, etal., Neuroscience. 2011 Jun 12.
Additional References at PubMed
PMID:11591709   PMID:11854273  


Genomics

Comparative Map Data
Cysltr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81554,599,043 - 54,638,314 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1554,598,818 - 54,713,597 (-)EnsemblGRCr8
mRatBN7.21548,189,476 - 48,228,750 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1548,189,073 - 48,304,136 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1552,335,467 - 52,371,705 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01553,447,041 - 53,483,279 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01550,280,153 - 50,323,717 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01554,903,290 - 54,941,742 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1554,905,274 - 54,906,203 (-)Ensemblrn6Rnor6.0
Rnor_5.01558,626,639 - 58,627,568 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41553,647,500 - 53,648,429 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1547,842,400 - 47,878,749 (-)NCBICelera
RGSC_v3.11553,663,279 - 53,664,209 (-)NCBI
Cytogenetic Map15p11NCBI
CYSLTR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381348,653,929 - 48,711,226 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1348,653,709 - 48,711,227 (+)Ensemblhg38GRCh38
GRCh371349,228,065 - 49,285,362 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361348,178,952 - 48,181,499 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341348,178,951 - 48,181,499NCBI
Celera1330,335,737 - 30,338,284 (+)NCBICelera
Cytogenetic Map13q14.2NCBI
HuRef1330,074,309 - 30,076,858 (+)NCBIHuRef
CHM1_11349,248,517 - 49,251,064 (+)NCBICHM1_1
T2T-CHM13v2.01347,874,204 - 47,931,486 (+)NCBIT2T-CHM13v2.0
Cysltr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391473,263,043 - 73,286,554 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1473,263,043 - 73,286,554 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381473,025,672 - 73,049,114 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1473,025,603 - 73,049,114 (-)Ensemblmm10GRCm38
MGSCv371473,428,935 - 73,448,921 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361471,764,210 - 71,784,144 (-)NCBIMGSCv36mm8
Celera1470,545,510 - 70,565,476 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1438.54NCBI
Cysltr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554312,263,698 - 2,282,635 (+)Ensembl
ChiLan1.0NW_0049554312,203,342 - 2,282,635 (+)NCBIChiLan1.0ChiLan1.0
CYSLTR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21450,096,264 - 50,153,487 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11348,747,376 - 48,804,604 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01329,796,598 - 29,853,676 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11348,497,679 - 48,556,159 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1348,551,757 - 48,552,797 (+)EnsemblpanPan2panpan1.1
CYSLTR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1222,914,960 - 2,962,517 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl222,917,514 - 2,918,551 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha222,942,924 - 2,990,494 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0222,903,750 - 2,951,364 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,906,323 - 2,907,360 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1222,813,420 - 2,861,018 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0222,859,844 - 2,924,179 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0222,881,301 - 2,928,917 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cysltr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945158,401,599 - 158,442,112 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365651,917,970 - 1,919,027 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYSLTR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1118,987,174 - 19,011,015 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11118,988,665 - 19,011,015 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21119,465,520 - 19,487,725 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYSLTR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1326,578,248 - 26,624,364 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605717,279,511 - 17,460,410 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cysltr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247486,040,564 - 6,043,454 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cysltr2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11251,379,857 - 51,381,005 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cysltr2
232 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:124
Interacting mature miRNAs:136
Transcripts:ENSRNOT00000020186
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
7411725Strs7Sensitivity to stroke QTL 73.8cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)154446544756583797Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 3 50 135 69 68 37 92 37 6 293 168 9 111 69 82 31 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000020186   ⟹   ENSRNOP00000020187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1554,905,274 - 54,906,203 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101826   ⟹   ENSRNOP00000095936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1548,190,320 - 48,278,229 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102995   ⟹   ENSRNOP00000083658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1548,189,073 - 48,197,531 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105845   ⟹   ENSRNOP00000091083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1554,598,818 - 54,637,294 (-)Ensembl
mRatBN7.2 Ensembl1548,189,073 - 48,304,136 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112031   ⟹   ENSRNOP00000083081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1548,190,245 - 48,227,991 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115019   ⟹   ENSRNOP00000087467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1554,598,818 - 54,638,621 (-)Ensembl
mRatBN7.2 Ensembl1548,190,245 - 48,304,136 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000132639   ⟹   ENSRNOP00000109886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1554,598,818 - 54,638,621 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000147034   ⟹   ENSRNOP00000112049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1554,598,859 - 54,637,565 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000154021   ⟹   ENSRNOP00000108565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1554,598,818 - 54,638,621 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155423   ⟹   ENSRNOP00000102185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1554,598,818 - 54,713,597 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000169893   ⟹   ENSRNOP00000100900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1554,601,009 - 54,663,951 (-)Ensembl
RefSeq Acc Id: NM_133413   ⟹   NP_596904
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81554,599,043 - 54,638,314 (-)NCBI
mRatBN7.21548,189,476 - 48,228,750 (-)NCBI
Rnor_6.01554,905,274 - 54,906,203 (-)NCBI
Rnor_5.01558,626,639 - 58,627,568 (-)NCBI
RGSC_v3.41553,647,500 - 53,648,429 (-)RGD
Sequence:
RefSeq Acc Id: NR_131894
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81554,600,853 - 54,638,314 (-)NCBI
mRatBN7.21548,191,286 - 48,228,750 (-)NCBI
Rnor_6.01554,904,221 - 54,940,071 (-)NCBI
Celera1547,842,400 - 47,878,749 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_596904 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB60816 (Get FASTA)   NCBI Sequence Viewer  
  CAJ58196 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000083081.1
  ENSRNOP00000083658.1
  ENSRNOP00000087467
  ENSRNOP00000087467.1
  ENSRNOP00000091083.1
  ENSRNOP00000095936.1
GenBank Protein Q924T9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_596904   ⟸   NM_133413
- UniProtKB: Q924T9 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020187   ⟸   ENSRNOT00000020186
Ensembl Acc Id: ENSRNOP00000095936   ⟸   ENSRNOT00000101826
Ensembl Acc Id: ENSRNOP00000091083   ⟸   ENSRNOT00000105845
Ensembl Acc Id: ENSRNOP00000087467   ⟸   ENSRNOT00000115019
Ensembl Acc Id: ENSRNOP00000083081   ⟸   ENSRNOT00000112031
Ensembl Acc Id: ENSRNOP00000083658   ⟸   ENSRNOT00000102995
Ensembl Acc Id: ENSRNOP00000102185   ⟸   ENSRNOT00000155423
Ensembl Acc Id: ENSRNOP00000100900   ⟸   ENSRNOT00000169893
Ensembl Acc Id: ENSRNOP00000109886   ⟸   ENSRNOT00000132639
Ensembl Acc Id: ENSRNOP00000112049   ⟸   ENSRNOT00000147034
Ensembl Acc Id: ENSRNOP00000108565   ⟸   ENSRNOT00000154021

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q924T9-F1-model_v2 AlphaFold Q924T9 1-309 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619797 AgrOrtholog
BioCyc Gene G2FUF-13172 BioCyc
Ensembl Genes ENSRNOG00000015042 Ensembl
  ENSRNOG00000067464 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000101826.1 UniProtKB/Swiss-Prot
  ENSRNOT00000102995.1 UniProtKB/Swiss-Prot
  ENSRNOT00000105845.1 UniProtKB/Swiss-Prot
  ENSRNOT00000112031.1 UniProtKB/Swiss-Prot
  ENSRNOT00000115019 ENTREZGENE
  ENSRNOT00000115019.1 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro CLT2_recept UniProtKB/Swiss-Prot
  Cyst_leuk_rcpt UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
KEGG Report rno:170926 UniProtKB/Swiss-Prot
NCBI Gene 170926 ENTREZGENE
PANTHER G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Cysltr2 PhenoGen
PRINTS CYSLT2RECPTR UniProtKB/Swiss-Prot
  CYSLTRECPTR UniProtKB/Swiss-Prot
  GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015042 RatGTEx
  ENSRNOG00000067464 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt CLTR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Cysltr2  cysteinyl leukotriene receptor 2  Cyslt2  cysteinyl leukotriene CysLT2 receptor  Symbol and Name updated 1299863 APPROVED
2002-08-07 Cyslt2  cysteinyl leukotriene CysLT2 receptor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function mouse homolog is a putative cysteinyl leukotriene receptor 704405