Mcm4 (minichromosome maintenance complex component 4) - Rat Genome Database

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Gene: Mcm4 (minichromosome maintenance complex component 4) Rattus norvegicus
Analyze
Symbol: Mcm4
Name: minichromosome maintenance complex component 4
RGD ID: 3060
Description: Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Predicted to be involved in DNA strand elongation involved in DNA replication; double-strand break repair via break-induced replication; and mitotic DNA replication initiation. Predicted to act upstream of or within DNA replication. Predicted to be located in chromosome. Predicted to be part of CMG complex and MCM complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 54. Orthologous to human MCM4 (minichromosome maintenance complex component 4); PARTICIPATES IN cell cycle pathway, mitotic; DNA replication pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA replication licensing factor MCM4; Mcmd4; mini chromosome maintenance deficient 4 homolog; mini chromosome maintenance deficient 4 homolog (S. cerevisiae); minichromosome maintenance deficient 4; minichromosome maintenance deficient 4 homolog; minichromosome maintenance deficient 4 homolog (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Mcm4-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81198,762,599 - 98,776,300 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1198,762,634 - 98,776,536 (+)EnsemblGRCr8
mRatBN7.21185,258,443 - 85,272,144 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1185,258,443 - 85,272,144 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1193,985,465 - 93,999,169 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01186,646,623 - 86,660,327 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01185,700,230 - 85,713,934 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,511,191 - 89,524,892 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,511,191 - 89,524,892 (+)Ensemblrn6Rnor6.0
Rnor_5.01192,565,514 - 92,579,215 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41187,169,742 - 87,183,443 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1183,998,817 - 84,012,516 (+)NCBICelera
RGSC_v3.11187,215,525 - 87,215,708 (+)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-citrinin  (ISO)
(-)-demecolcine  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4,6-tribromophenol  (ISO)
2-butoxyethanol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-methylcholanthrene  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atropine  (ISO)
avobenzone  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
corticosterone  (EXP)
coumarin  (EXP,ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
DDT  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl maleate  (EXP)
dioxygen  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
equol  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
geldanamycin  (ISO)
glycine betaine  (EXP)
glyphosate  (ISO)
GSK-J4  (ISO)
GW 3965  (ISO)
GW 4064  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
lead(0)  (ISO)
lidocaine  (EXP)
lithium chloride  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel dichloride  (ISO)
nimesulide  (EXP)
nitrates  (ISO)
Nonylphenol  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
silicon dioxide  (ISO)
silver(1+) nitrate  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP,ISO)
troglitazone  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IEA)
MCM complex  (IBA,IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:9305914   PMID:15917436   PMID:17296731   PMID:19135898   PMID:19946888   PMID:22082260   PMID:23264620   PMID:31505169  


Genomics

Comparative Map Data
Mcm4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81198,762,599 - 98,776,300 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1198,762,634 - 98,776,536 (+)EnsemblGRCr8
mRatBN7.21185,258,443 - 85,272,144 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1185,258,443 - 85,272,144 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1193,985,465 - 93,999,169 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01186,646,623 - 86,660,327 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01185,700,230 - 85,713,934 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,511,191 - 89,524,892 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,511,191 - 89,524,892 (+)Ensemblrn6Rnor6.0
Rnor_5.01192,565,514 - 92,579,215 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41187,169,742 - 87,183,443 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1183,998,817 - 84,012,516 (+)NCBICelera
RGSC_v3.11187,215,525 - 87,215,708 (+)NCBI
Cytogenetic Map11q23NCBI
MCM4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38847,960,941 - 47,978,160 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl847,960,185 - 47,978,165 (+)Ensemblhg38GRCh38
GRCh37848,873,501 - 48,890,720 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36849,036,047 - 49,052,621 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34849,036,046 - 49,052,621NCBI
Celera844,858,902 - 44,875,475 (+)NCBICelera
Cytogenetic Map8q11.21NCBI
HuRef844,335,726 - 44,353,327 (+)NCBIHuRef
CHM1_1848,925,125 - 48,943,082 (+)NCBICHM1_1
T2T-CHM13v2.0848,337,189 - 48,354,408 (+)NCBIT2T-CHM13v2.0
Mcm4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391615,441,761 - 15,455,264 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1615,441,761 - 15,455,264 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381615,623,897 - 15,637,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1615,623,897 - 15,637,400 (-)Ensemblmm10GRCm38
MGSCv371615,623,990 - 15,637,493 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361615,537,681 - 15,550,934 (-)NCBIMGSCv36mm8
Celera1616,200,304 - 16,213,825 (-)NCBICelera
Cytogenetic Map16A2NCBI
cM Map1610.09NCBI
Mcm4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554547,891,456 - 7,908,462 (+)Ensembl
ChiLan1.0NW_0049554547,891,646 - 7,908,240 (+)NCBIChiLan1.0ChiLan1.0
MCM4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2763,594,184 - 63,611,453 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1839,287,937 - 39,304,974 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0844,387,529 - 44,404,773 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1841,779,624 - 41,794,996 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl841,778,247 - 41,794,783 (+)EnsemblpanPan2panpan1.1
MCM4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.129244,634 - 261,154 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl29244,656 - 260,991 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha29670,093 - 687,010 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.029242,674 - 259,603 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl29242,628 - 259,596 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.129241,027 - 256,505 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.029435,880 - 453,002 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.029504,123 - 521,263 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mcm4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530379,515,218 - 79,532,505 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365904,704,972 - 4,722,427 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365904,705,028 - 4,722,320 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCM4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl479,674,739 - 79,686,685 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1479,674,737 - 79,686,964 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2487,134,029 - 87,142,341 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCM4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1844,120,291 - 44,136,625 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl844,120,301 - 44,138,193 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603997,951,742 - 97,968,921 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mcm4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247357,516,516 - 7,533,760 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247357,516,510 - 7,533,789 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mcm4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14971,842 - 985,937 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:174
Count of miRNA genes:129
Interacting mature miRNAs:140
Transcripts:ENSRNOT00000002510
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat

Markers in Region
RH134441  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22141,554,236 - 141,554,419 (+)MAPPERmRatBN7.2
mRatBN7.21185,271,807 - 85,271,994 (+)MAPPERmRatBN7.2
Rnor_6.01189,524,556 - 89,524,742NCBIRnor6.0
Rnor_6.02147,480,234 - 147,480,416NCBIRnor6.0
Rnor_5.01192,578,879 - 92,579,065UniSTSRnor5.0
Rnor_5.02166,889,221 - 166,889,403UniSTSRnor5.0
RGSC_v3.42146,617,085 - 146,617,267UniSTSRGSC3.4
RGSC_v3.41187,183,107 - 87,183,293UniSTSRGSC3.4
Celera1184,012,180 - 84,012,366UniSTS
Celera2136,007,187 - 136,007,369UniSTS
RH 3.4 Map2860.0UniSTS
Cytogenetic Map11q23.2UniSTS
Cytogenetic Map2q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002510   ⟹   ENSRNOP00000002510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1198,762,634 - 98,776,536 (+)Ensembl
mRatBN7.2 Ensembl1185,258,443 - 85,272,144 (+)Ensembl
Rnor_6.0 Ensembl1189,511,191 - 89,524,892 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098009   ⟹   ENSRNOP00000090013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1185,258,443 - 85,272,132 (+)Ensembl
RefSeq Acc Id: NM_033651   ⟹   NP_387500
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81198,762,599 - 98,776,300 (+)NCBI
mRatBN7.21185,258,443 - 85,272,144 (+)NCBI
Rnor_6.01189,511,191 - 89,524,892 (+)NCBI
Rnor_5.01192,565,514 - 92,579,215 (+)NCBI
RGSC_v3.41187,169,742 - 87,183,443 (+)RGD
Celera1183,998,817 - 84,012,516 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_387500 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK01320 (Get FASTA)   NCBI Sequence Viewer  
  EDL77837 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002510
  ENSRNOP00000002510.5
RefSeq Acc Id: NP_387500   ⟸   NM_033651
- UniProtKB: G3V681 (UniProtKB/TrEMBL),   A6JSR9 (UniProtKB/TrEMBL),   A0A8I6AAZ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002510   ⟸   ENSRNOT00000002510
Ensembl Acc Id: ENSRNOP00000090013   ⟸   ENSRNOT00000098009
Protein Domains
MCM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V681-F1-model_v2 AlphaFold G3V681 1-862 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698352
Promoter ID:EPDNEW_R8877
Type:initiation region
Name:Mcm4_1
Description:minichromosome maintenance complex component 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01189,511,256 - 89,511,316EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3060 AgrOrtholog
BioCyc Gene G2FUF-20540 BioCyc
Ensembl Genes ENSRNOG00000001833 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002510 ENTREZGENE
  ENSRNOT00000002510.8 UniProtKB/TrEMBL
Gene3D-CATH 2.20.28.10 UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  mini-chromosome maintenance (MCM) complex, chain A, domain 1 UniProtKB/TrEMBL
InterPro MCM UniProtKB/TrEMBL
  MCM_4 UniProtKB/TrEMBL
  MCM_CS UniProtKB/TrEMBL
  MCM_DNA-dep_ATPase UniProtKB/TrEMBL
  MCM_lid UniProtKB/TrEMBL
  MCM_N UniProtKB/TrEMBL
  MCM_OB UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:29728 UniProtKB/TrEMBL
NCBI Gene 29728 ENTREZGENE
PANTHER PTHR11630 UniProtKB/TrEMBL
  PTHR11630:SF66 UniProtKB/TrEMBL
Pfam MCM UniProtKB/TrEMBL
  MCM4_WHD UniProtKB/TrEMBL
  MCM_lid UniProtKB/TrEMBL
  MCM_N UniProtKB/TrEMBL
  MCM_OB UniProtKB/TrEMBL
PhenoGen Mcm4 PhenoGen
PRINTS MCMFAMILY UniProtKB/TrEMBL
  MCMPROTEIN4 UniProtKB/TrEMBL
PROSITE MCM_1 UniProtKB/TrEMBL
  MCM_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001833 RatGTEx
SMART MCM UniProtKB/TrEMBL
Superfamily-SCOP Nucleic_acid_OB UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6AAZ2 ENTREZGENE
  A6JSR9 ENTREZGENE, UniProtKB/TrEMBL
  G3V681 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-24 Mcm4  minichromosome maintenance complex component 4  Mcm4  minichromosome maintenance deficient 4 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Mcm4  minichromosome maintenance deficient 4 homolog (S. cerevisiae)  Mcmd4  mini chromosome maintenance deficient 4 homolog (S. cerevisiae)  Symbol and Name updated 1299863 APPROVED
2002-06-10 Mcmd4  Mini chromosome maintenance deficient 4 homolog (S. cerevisiae)      Symbol and Name status set to approved 70586 APPROVED