Symbol:
Amelx
Name:
amelogenin, X-linked
RGD ID:
2107
Description:
Enables identical protein binding activity. A structural constituent of tooth enamel. Involved in response to calcium ion; response to nutrient; and response to xenobiotic stimulus. Located in endocytic vesicle. Biomarker of autosomal dominant hypocalcemia. Human ortholog(s) of this gene implicated in amelogenesis imperfecta and amelogenesis imperfecta type 1E. Orthologous to several human genes including AMELX (amelogenin X-linked); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
Amel; amelogenin; amelogenin X chromosome; amelogenin, X isoform; leucine-rich amelogenin peptide; LRAP
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
AMELX (amelogenin X-linked) HGNC
Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Amelx (amelogenin, X-linked) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Amelx (amelogenin X-linked) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
AMELY (amelogenin Y-linked) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
AMELX (amelogenin X-linked) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Amelx (amelogenin X-linked) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
AMELX (amelogenin X-linked) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
AMELX (amelogenin X-linked) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Amelx (amelogenin X-linked) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
AMELY (amelogenin Y-linked) HGNC
Inparanoid, OrthoDB, Panther
Alliance orthologs 3
Homo sapiens (human):
AMELX (amelogenin X-linked)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|OMA|OrthoFinder|PANTHER)
Mus musculus (house mouse):
Amelx (amelogenin, X-linked)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
AMELY (amelogenin Y-linked)
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
amelx
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 28,648,803 - 28,660,099 (+) NCBI GRCr8 mRatBN7.2 X 25,076,362 - 25,087,660 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 25,076,362 - 25,087,660 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 26,080,937 - 26,092,217 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 29,502,009 - 29,513,289 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 25,735,122 - 25,746,420 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 26,439,197 - 26,450,495 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 26,439,197 - 26,450,495 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 45,763,451 - 45,769,374 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 X 45,816,919 - 45,822,842 (+) NCBI Celera X 25,496,279 - 25,507,557 (+) NCBI Celera Cytogenetic Map X q13 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Molecular Function
calcium ion binding (IEA,ISO) growth factor activity (IEA,ISO) hydroxyapatite binding (IEA,ISO) identical protein binding (IDA,IEA,ISO) protein binding (ISO) protein homodimerization activity (IEA,ISO) sodium ion binding (IEA,ISO) structural constituent of tooth enamel (IBA,IDA,IEA,ISO,TAS)
1.
Molecular cloning and DNA sequence of rat amelogenin and a comparative analysis of mammalian amelogenin protein sequence divergence.
Bonass WA, etal., Biochem Biophys Res Commun 1994 Jan 28;198(2):755-63.
2.
Intracellular nanosphere subunit assembly as revealed by amelogenin molecular cross-linking studies.
Brookes SJ, etal., Eur J Oral Sci. 2006 May;114 Suppl 1:280-4; discussion 285-6, 382.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
Amelogenin-deficient mice display an amelogenesis imperfecta phenotype.
Gibson CW, etal., J Biol Chem 2001 Aug 24;276(34):31871-5. Epub 2001 Jun 13.
5.
Molecular basis and consequences of a deletion in the amelogenin gene, analyzed by capture PCR.
Lagerstrom-Fermer M, etal., Genomics 1993 Jul;17(1):89-92.
6.
Alternative splicing of amelogenin mRNA from rat incisor ameloblasts.
Li R, etal., J Dent Res 1995 Dec;74(12):1880-5.
7.
Immunocytochemical study of amelogenin deposition during the early odontogenesis of molars in alendronate-treated newborn rats.
Massa LF, etal., J Histochem Cytochem. 2006 Jun;54(6):713-25. Epub 2006 Feb 6.
8.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
9.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.
Internalization of amelogenin by dendritic cells of the papillary layer during transition and early maturation stages.
Nishikawa S and Sasaki F, Histochem Cell Biol. 1999 Oct;112(4):301-5.
11.
OMIM Disease Annotation Pipeline
OMIM Disease Annotation Pipeline
12.
Expression of amelogenin in odontoblasts.
Papagerakis P, etal., Bone. 2003 Mar;32(3):228-40.
13.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
15.
Changes in amelogenesis in the rat incisor following short-term hypocalcaemia.
Yamaguti PM, etal., Arch Oral Biol. 2005 Feb;50(2):185-8.
Amelx Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 28,648,803 - 28,660,099 (+) NCBI GRCr8 mRatBN7.2 X 25,076,362 - 25,087,660 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 25,076,362 - 25,087,660 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 26,080,937 - 26,092,217 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 29,502,009 - 29,513,289 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 25,735,122 - 25,746,420 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 26,439,197 - 26,450,495 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 26,439,197 - 26,450,495 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 45,763,451 - 45,769,374 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 X 45,816,919 - 45,822,842 (+) NCBI Celera X 25,496,279 - 25,507,557 (+) NCBI Celera Cytogenetic Map X q13 NCBI
AMELX Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 X 11,293,413 - 11,309,588 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl X 11,293,413 - 11,300,761 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 X 11,311,533 - 11,318,881 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 X 11,221,454 - 11,228,802 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Celera X 15,438,990 - 15,446,338 (+) NCBI Celera Cytogenetic Map X p22.2 NCBI HuRef X 9,091,155 - 9,098,355 (+) NCBI HuRef CHM1_1 X 11,342,001 - 11,349,349 (+) NCBI CHM1_1 T2T-CHM13v2.0 X 10,875,912 - 10,892,087 (+) NCBI T2T-CHM13v2.0
Amelx Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 X 167,959,110 - 167,970,205 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl X 167,959,110 - 167,970,196 (-) Ensembl GRCm39 Ensembl GRCm38 X 169,176,114 - 169,187,209 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl X 169,176,114 - 169,187,200 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 X 165,614,046 - 165,625,141 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 X 164,524,127 - 164,531,314 (-) NCBI MGSCv36 mm8 Celera X 152,339,918 - 152,351,218 (-) NCBI Celera Cytogenetic Map X F5 NCBI cM Map X 78.95 NCBI
Amelx Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955544 1,969,216 - 1,979,063 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955544 1,974,889 - 1,979,063 (-) NCBI ChiLan1.0 ChiLan1.0
AMELY Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 Y 43,791,359 - 44,000,131 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 Y 2,926,868 - 3,135,641 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 X 3,898,819 - 3,930,686 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 X 11,214,103 - 11,221,443 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl X 11,214,103 - 11,221,443 (+) Ensembl panpan1.1 panPan2
AMELX Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 X 7,822,513 - 7,828,692 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl X 7,822,859 - 7,830,351 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha X 7,779,650 - 7,787,144 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 X 7,776,327 - 7,783,824 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl X 7,776,321 - 7,783,816 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 X 7,759,322 - 7,766,816 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 X 7,795,375 - 7,802,872 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 X 7,790,231 - 7,797,728 (+) NCBI UU_Cfam_GSD_1.0
Amelx Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 X 1,168,483 - 1,174,166 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936470 1,169,906 - 1,179,604 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936470 1,169,906 - 1,174,166 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
AMELX Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl X 8,055,782 - 8,063,449 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 X 8,055,246 - 8,063,457 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 X 8,669,948 - 8,677,620 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
AMELX Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 X 9,927,740 - 9,934,104 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl X 9,741,594 - 9,745,776 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 ChlSab1.1 Ensembl X 9,741,594 - 9,745,776 (+) NCBI ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666056 11,535,786 - 11,539,980 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Amelx
.
Predicted Target Of
Count of predictions: 106 Count of miRNA genes: 89 Interacting mature miRNAs: 98 Transcripts: ENSRNOT00000005328, ENSRNOT00000052176 Prediction methods: Microtar, Miranda, Pita, Rnahybrid, Targetscan Result types: miRGate_prediction
1598873 Memor2 Memory QTL 2 2.5 exploratory behavior trait (VT:0010471) average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674) X 20990947 41052531 Rat 70165 Bp64 Blood pressure QTL 64 5.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) X 1448129 31706553 Rat 1298071 Edpm12 Estrogen-dependent pituitary mass QTL 12 3.2 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) X 2927898 47927898 Rat 2290375 Gluco34 Glucose level QTL 34 2.75 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) X 20990947 41203591 Rat 731181 Uae27 Urinary albumin excretion QTL 27 2.7 0.0059 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) X 1 43491017 Rat 61430 Cia18 Collagen induced arthritis QTL 18 3.1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) X 14843113 120568734 Rat 10755455 Coatc13 Coat color QTL 13 0 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 7 4406000 49406000 Rat 631666 Iddm5 Insulin dependent diabetes mellitus QTL 5 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) X 4494549 49494549 Rat 71116 Niddm16 Non-insulin dependent diabetes mellitus QTL 16 7.81 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) X 15297802 60297802 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
3
10
14
45
31
36
12
20
12
1
85
49
35
13
15
24
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000005328 ⟹ ENSRNOP00000005328
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 25,077,763 - 25,081,877 (+) Ensembl Rnor_6.0 Ensembl X 26,440,598 - 26,445,191 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000052176 ⟹ ENSRNOP00000048382
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 25,076,362 - 25,087,660 (+) Ensembl Rnor_6.0 Ensembl X 26,439,197 - 26,450,495 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000078843 ⟹ ENSRNOP00000069787
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 25,076,362 - 25,083,664 (+) Ensembl Rnor_6.0 Ensembl X 26,439,197 - 26,446,499 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000087268 ⟹ ENSRNOP00000068556
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 25,076,362 - 25,087,660 (+) Ensembl Rnor_6.0 Ensembl X 26,439,197 - 26,450,495 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000087293 ⟹ ENSRNOP00000075671
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl X 26,440,584 - 26,446,499 (+) Ensembl
RefSeq Acc Id:
NM_001271073 ⟹ NP_001258002
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 28,648,803 - 28,660,099 (+) NCBI mRatBN7.2 X 25,076,362 - 25,087,660 (+) NCBI Rnor_6.0 X 26,439,197 - 26,450,495 (+) NCBI Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI Celera X 25,496,279 - 25,507,557 (+) NCBI
Sequence:
TCGGATCAAGCATCCCTGAGCTTCAGACAGAAAGTCACTGAGCATACACTCAAGAACCATCAAGAAATGGGGACCTGGATCTTGTTTGCCTGCCTCCTGGGAGCAGCTTTTGCTATGCCCCTACCACC
hide sequence
RefSeq Acc Id:
NM_001271074 ⟹ NP_001258003
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 28,648,803 - 28,660,099 (+) NCBI mRatBN7.2 X 25,076,362 - 25,087,660 (+) NCBI Rnor_6.0 X 26,439,197 - 26,450,495 (+) NCBI Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI Celera X 25,496,279 - 25,507,557 (+) NCBI
Sequence:
TCGGATCAAGCATCCCTGAGCTTCAGACAGAAAGTCACTGAGCATACACTCAAGAACCATCAAGAAATGGGGACCTGGATCTTGTTTGCCTGCCTCCTGGGAGCAGCTTTTGCTATGCCCCTACCACC
hide sequence
RefSeq Acc Id:
NM_001271075 ⟹ NP_001258004
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 28,648,803 - 28,660,099 (+) NCBI mRatBN7.2 X 25,076,362 - 25,087,660 (+) NCBI Rnor_6.0 X 26,439,197 - 26,450,495 (+) NCBI Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI Celera X 25,496,279 - 25,507,557 (+) NCBI
Sequence:
TCGGATCAAGCATCCCTGAGCTTCAGACAGAAAGTCACTGAGCATACACTCAAGAACCATCAAG
hide sequence
RefSeq Acc Id:
NM_001271076 ⟹ NP_001258005
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 28,648,803 - 28,660,099 (+) NCBI mRatBN7.2 X 25,076,362 - 25,087,660 (+) NCBI Rnor_6.0 X 26,439,197 - 26,450,495 (+) NCBI Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI Celera X 25,496,279 - 25,507,557 (+) NCBI
Sequence:
TCGGATCAAGCATCCCTGAGCTTCAGACAGAAAGTCACTGAGCATACACTCAAGAACCATCAAGAAATGGGGACCTGGATCTTGTTTGCCTGCCTCCTGGGAGCAGCTTTTGCTATGCCCCTACCACC
hide sequence
RefSeq Acc Id:
NM_001271077 ⟹ NP_001258006
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 28,648,803 - 28,656,111 (+) NCBI mRatBN7.2 X 25,076,362 - 25,083,672 (+) NCBI Rnor_6.0 X 26,439,197 - 26,446,507 (+) NCBI Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI Celera X 25,496,279 - 25,503,569 (+) NCBI
Sequence:
TCGGATCAAGCATCCCTGAGCTTCAGACAGAAAGTCACTGAGCATACACTCAAGAACCATCAAGAAATGGGGACCTGGATCTTGTTTGCCTGCCTCCTGGGAGCAGCTTTTGCTATGCCCCTACCACC
hide sequence
RefSeq Acc Id:
NM_001271078 ⟹ NP_001258007
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 28,648,803 - 28,656,111 (+) NCBI mRatBN7.2 X 25,076,362 - 25,083,672 (+) NCBI Rnor_6.0 X 26,439,197 - 26,446,507 (+) NCBI Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI Celera X 25,496,279 - 25,503,569 (+) NCBI
Sequence:
TCGGATCAAGCATCCCTGAGCTTCAGACAGAAAGTCACTGAGCATACACTCAAGAACCATCAAG
hide sequence
RefSeq Acc Id:
NM_019154 ⟹ NP_062027
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 28,648,803 - 28,656,111 (+) NCBI mRatBN7.2 X 25,076,362 - 25,083,672 (+) NCBI Rnor_6.0 X 26,440,584 - 26,446,507 (+) NCBI Rnor_5.0 X 26,843,989 - 26,855,287 (+) NCBI RGSC_v3.4 X 45,763,451 - 45,769,374 (+) RGD Celera X 25,497,666 - 25,503,569 (+) NCBI
Sequence:
AAGAACCATCAAGAAATGGGGACCTGGATCTTGTTTGCCTGCCTCCTGGGAGCAGCTTTTGCTATGCCCCTACCACCTCATCCTGGGAGCCCTGGTTATATCAACTTAAGCTATGAGAAGTCACATTC
hide sequence
RefSeq Acc Id:
NP_062027 ⟸ NM_019154
- Peptide Label:
isoform 5 precursor
- UniProtKB:
Q63640 (UniProtKB/Swiss-Prot), Q62945 (UniProtKB/Swiss-Prot), Q78E56 (UniProtKB/Swiss-Prot), P63278 (UniProtKB/Swiss-Prot), A6K2F1 (UniProtKB/TrEMBL), A0A8L2UHN6 (UniProtKB/TrEMBL)
- Sequence:
MGTWILFACLLGAAFAMPLPPHPGSPGYINLSYEKSHSQAINTDRTALVLTPLKWYQSMIRQPYPSYGYEPMGGWLHHQIIPVLSQQHPPSHTLQPHHHLPVVPAQQPVAPQQPMMPVPGHHSMTPTQ
hide sequence
RefSeq Acc Id:
NP_001258003 ⟸ NM_001271074
- Peptide Label:
isoform 1 precursor
- UniProtKB:
A6K2E8 (UniProtKB/TrEMBL), A0A8L2UHN6 (UniProtKB/TrEMBL)
- Sequence:
MGTWILFACLLGAAFAMPLPPHPGSPGYINLSYEVLTPLKWYQSMIRQPYPSYGYEPMGGWLHHQIIPVLSQQHPPSHTLQPHHHLPVVPAQQPVAPQQPMMPVPGHHSMTPTQHHQPNIPPSAQQPF
hide sequence
RefSeq Acc Id:
NP_001258002 ⟸ NM_001271073
- Peptide Label:
isoform 2 precursor
- UniProtKB:
A6K2E9 (UniProtKB/TrEMBL)
- Sequence:
MGTWILFACLLGAAFAMPLPPHPGSPGYINLSYEVLTPLKWYQSMIRQPHPPSHTLQPHHHLPVVPAQQPVAPQQPMMPVPGHHSMTPTQHHQPNIPPSAQQPFQQPFQPQAIPPQSHQPMQPQSPLH
hide sequence
RefSeq Acc Id:
NP_001258004 ⟸ NM_001271075
- Peptide Label:
isoform 3 precursor
- UniProtKB:
Q63642 (UniProtKB/TrEMBL), A6K2F0 (UniProtKB/TrEMBL)
- Sequence:
MGTWILFACLLGAAFAMPLPPHPGSPGYINLSYEVLTPLKWYQSMIRQPPLSPILPELPLEAWPATDKTKREEVAFSPMKWYQGTARHPLNMETTTEK
hide sequence
RefSeq Acc Id:
NP_001258005 ⟸ NM_001271076
- Peptide Label:
isoform 4 precursor
- UniProtKB:
A0A0G2JT37 (UniProtKB/TrEMBL)
- Sequence:
MGTWILFACLLGAAFAMPLPPHPGSPGYINLSYEVLTPLKWYQSMIRQPAFSPMKWYQGTARHPLNMETTTEK
hide sequence
RefSeq Acc Id:
NP_001258006 ⟸ NM_001271077
- Peptide Label:
isoform 6 precursor
- UniProtKB:
A6K2F2 (UniProtKB/TrEMBL), A0A8L2UHN6 (UniProtKB/TrEMBL)
- Sequence:
MGTWILFACLLGAAFAMPLPPHPGSPGYINLSYEVLTPLKWYQSMIRQPYPSYGYEPMGGWLHHQIIPVLSQQHPPSHTLQPHHHLPVVPAQQPVAPQQPMMPVPGHHSMTPTQHHQPNIPPSAQQPF
hide sequence
RefSeq Acc Id:
NP_001258007 ⟸ NM_001271078
- Peptide Label:
isoform 7 precursor
- UniProtKB:
A6K2F3 (UniProtKB/TrEMBL)
- Sequence:
MGTWILFACLLGAAFAMPLPPHPGSPGYINLSYEVLTPLKWYQSMIRQPPLSPILPELPLEAWPATDKTKREEVD
hide sequence
Ensembl Acc Id:
ENSRNOP00000075671 ⟸ ENSRNOT00000087293
Ensembl Acc Id:
ENSRNOP00000068556 ⟸ ENSRNOT00000087268
Ensembl Acc Id:
ENSRNOP00000005328 ⟸ ENSRNOT00000005328
Ensembl Acc Id:
ENSRNOP00000069787 ⟸ ENSRNOT00000078843
Ensembl Acc Id:
ENSRNOP00000048382 ⟸ ENSRNOT00000052176
BioCyc Gene G2FUF-2677 BioCyc
Ensembl Genes ENSRNOG00000003965 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000052176 ENTREZGENE
ENSRNOT00000052176.5 UniProtKB/Swiss-Prot
ENSRNOT00000078843 ENTREZGENE
ENSRNOT00000078843.2 UniProtKB/Swiss-Prot
ENSRNOT00000087268 ENTREZGENE
InterPro Amelogenin UniProtKB/Swiss-Prot
KEGG Report rno:29160 UniProtKB/Swiss-Prot
NCBI Gene 29160 ENTREZGENE
PANTHER AMELOGENIN, Y ISOFORM UniProtKB/Swiss-Prot
PTHR46794 UniProtKB/Swiss-Prot
Pfam Amelogenin UniProtKB/Swiss-Prot
PhenoGen Amelx PhenoGen
PRINTS AMELOGENIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003965 RatGTEx
SMART Amelogenin UniProtKB/Swiss-Prot
UniProt A0A0G2JT37 ENTREZGENE, UniProtKB/TrEMBL
A0A8L2UHN6 ENTREZGENE, UniProtKB/TrEMBL
A6K2E8 ENTREZGENE, UniProtKB/TrEMBL
A6K2E9 ENTREZGENE, UniProtKB/TrEMBL
A6K2F0 ENTREZGENE, UniProtKB/TrEMBL
A6K2F1 ENTREZGENE, UniProtKB/TrEMBL
A6K2F2 ENTREZGENE, UniProtKB/TrEMBL
A6K2F3 ENTREZGENE, UniProtKB/TrEMBL
AMELX_RAT UniProtKB/Swiss-Prot
B2BY38_RAT UniProtKB/TrEMBL
P63278 ENTREZGENE
Q62945 ENTREZGENE
Q63640 ENTREZGENE
Q63641_RAT UniProtKB/TrEMBL
Q63642 ENTREZGENE, UniProtKB/TrEMBL
Q78E56 ENTREZGENE
UniProt Secondary P45559 UniProtKB/Swiss-Prot
Q62945 UniProtKB/Swiss-Prot
Q63640 UniProtKB/Swiss-Prot
Q78E56 UniProtKB/Swiss-Prot
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2012-01-06
Amelx
amelogenin, X-linked
Amelx
amelogenin X chromosome
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2004-03-01
Amelx
amelogenin X chromosome
Amel
amelogenin
Symbol and Name updated to reflect Human and Mouse nomenclature
625702 APPROVED
2002-06-10
Amel
amelogenin
Symbol and Name status set to approved
70586 APPROVED
Note Type
Note
Reference
gene_function
structural component of the enamel matrix
632201
gene_process
may play a role in mineralization
632201
