Hira (histone cell cycle regulator) - Rat Genome Database

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Gene: Hira (histone cell cycle regulator) Rattus norvegicus
Analyze
Symbol: Hira
Name: histone cell cycle regulator
RGD ID: 1584950
Description: Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and histone binding activity. Predicted to contribute to nucleosome binding activity. Predicted to be involved in nucleosome assembly. Predicted to act upstream of or within gastrulation; muscle cell differentiation; and osteoblast differentiation. Predicted to be located in nucleus. Predicted to be part of HIR complex. Predicted to be active in chromatin. Orthologous to human HIRA (histone cell cycle regulator); PARTICIPATES IN histone modification pathway; INTERACTS WITH 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: HIR histone cell cycle regulation defective homolog A; HIR histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulation defective homolog A; LOC100911837; LOC363849; protein HIRA-like; similar to histone cell cycle regulation defective homolog A isoform 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81195,528,831 - 95,637,565 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1195,528,831 - 95,638,549 (-)EnsemblGRCr8
mRatBN7.21182,024,469 - 82,133,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,024,469 - 82,133,529 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1190,753,636 - 90,862,674 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,414,851 - 83,523,894 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,468,120 - 82,577,162 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,168,196 - 86,276,430 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,168,196 - 86,276,430 (-)Ensemblrn6Rnor6.0
Rnor_5.01189,270,162 - 89,378,396 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera1180,805,603 - 80,913,841 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Histone chaperones in nucleosome assembly and human disease. Burgess RJ and Zhang Z, Nat Struct Mol Biol. 2013 Jan;20(1):14-22. doi: 10.1038/nsmb.2461.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. HIRA Gene is Lower Expressed in the Myocardium of Patients with Tetralogy of Fallot. Ju ZR, etal., Chin Med J (Engl). 2016 Oct 20;129(20):2403-2408. doi: 10.4103/0366-6999.191745.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis. Valenzuela N, etal., Dis Model Mech. 2016 Mar;9(3):335-45. doi: 10.1242/dmm.022889.
Additional References at PubMed
PMID:11884616   PMID:14718166   PMID:15922569   PMID:18570454   PMID:22705305  


Genomics

Comparative Map Data
Hira
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81195,528,831 - 95,637,565 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1195,528,831 - 95,638,549 (-)EnsemblGRCr8
mRatBN7.21182,024,469 - 82,133,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,024,469 - 82,133,529 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1190,753,636 - 90,862,674 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,414,851 - 83,523,894 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,468,120 - 82,577,162 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,168,196 - 86,276,430 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,168,196 - 86,276,430 (-)Ensemblrn6Rnor6.0
Rnor_5.01189,270,162 - 89,378,396 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera1180,805,603 - 80,913,841 (-)NCBICelera
Cytogenetic Map11q23NCBI
HIRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,330,698 - 19,431,733 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,330,693 - 19,447,450 (-)Ensemblhg38GRCh38
GRCh372219,318,221 - 19,419,256 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,698,224 - 17,799,219 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342217,692,777 - 17,793,773NCBI
Celera223,170,348 - 3,271,476 (-)NCBICelera
Cytogenetic Map22q11.21ENTREZGENE
HuRef222,938,779 - 3,039,800 (-)NCBIHuRef
CHM1_12219,317,795 - 19,418,793 (-)NCBICHM1_1
T2T-CHM13v2.02219,707,409 - 19,808,564 (-)NCBIT2T-CHM13v2.0
Hira
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,695,500 - 18,789,059 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,695,787 - 18,789,059 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381618,876,750 - 18,970,309 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,877,037 - 18,970,309 (+)Ensemblmm10GRCm38
MGSCv371618,876,843 - 18,970,402 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361618,790,313 - 18,883,872 (+)NCBIMGSCv36mm8
Celera1619,450,807 - 19,544,362 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.69NCBI
LOC102009660
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544218,581,370 - 18,673,761 (+)Ensembl
ChiLan1.0NW_00495544218,581,370 - 18,673,590 (+)NCBIChiLan1.0ChiLan1.0
LOC100977781
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22328,955,170 - 29,056,833 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,498,613 - 31,604,572 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,087,846 - 2,191,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12217,765,598 - 17,845,654 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2217,765,598 - 17,847,084 (-)EnsemblpanPan2panpan1.1
HIRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,777,984 - 29,867,992 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,778,086 - 29,867,559 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2629,733,351 - 29,822,268 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02631,179,782 - 31,268,951 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,179,884 - 31,268,655 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,227,072 - 29,316,422 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,852,492 - 28,941,149 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,939,424 - 30,028,570 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101957075
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,372,372 - 139,471,877 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366193,282,173 - 3,380,151 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366193,282,170 - 3,380,151 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,029,126 - 51,102,409 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11451,029,117 - 51,102,409 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,596,123 - 54,669,440 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HIRA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,324,050 - 6,424,999 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,324,253 - 6,425,641 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666085508,725 - 609,791 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101713307
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247479 - 95,643 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
LOC116898681
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v144,123,424 - 4,228,737 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:325
Count of miRNA genes:206
Interacting mature miRNAs:241
Transcripts:ENSRNOT00000075164
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)119046178196556255Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
D11Got81  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,126,584 - 82,126,804 (+)MAPPERmRatBN7.2
Rnor_6.01186,269,803 - 86,270,022NCBIRnor6.0
Rnor_5.01189,371,769 - 89,371,988UniSTSRnor5.0
Celera1180,907,218 - 80,907,437UniSTS
RH 3.4 Map11698.3RGD
RH 3.4 Map11698.3UniSTS
BE115254  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,091,728 - 82,091,892 (+)MAPPERmRatBN7.2
Rnor_6.01185,870,299 - 85,870,462NCBIRnor6.0
Rnor_6.01186,235,449 - 86,235,612NCBIRnor6.0
Rnor_5.01189,337,415 - 89,337,578UniSTSRnor5.0
Rnor_5.01188,970,630 - 88,970,793UniSTSRnor5.0
Celera1180,872,849 - 80,873,012UniSTS
RH 3.4 Map11694.1UniSTS
Hira  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,132,470 - 82,132,627 (+)MAPPERmRatBN7.2
Rnor_6.01186,275,689 - 86,275,845NCBIRnor6.0
Rnor_5.01189,377,655 - 89,377,811UniSTSRnor5.0
Celera1180,913,100 - 80,913,256UniSTS
Cytogenetic Map11p12UniSTS
D22S1095E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,024,581 - 82,024,683 (+)MAPPERmRatBN7.2
Rnor_6.01185,802,649 - 85,802,750NCBIRnor6.0
Rnor_6.01186,168,309 - 86,168,410NCBIRnor6.0
Rnor_5.01189,270,275 - 89,270,376UniSTSRnor5.0
Rnor_5.01188,902,980 - 88,903,081UniSTSRnor5.0
Celera1180,805,716 - 80,805,817UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 89 88 57 92 57 6 354 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001135760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010055965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000071462   ⟹   ENSRNOP00000065274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1195,528,831 - 95,638,549 (-)Ensembl
mRatBN7.2 Ensembl1182,024,469 - 82,133,529 (-)Ensembl
Rnor_6.0 Ensembl1185,802,605 - 85,895,613 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075164   ⟹   ENSRNOP00000064357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1195,528,831 - 95,637,565 (-)Ensembl
mRatBN7.2 Ensembl1182,024,469 - 82,133,212 (-)Ensembl
Rnor_6.0 Ensembl1186,168,196 - 86,276,430 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000121679   ⟹   ENSRNOP00000098904
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1195,528,831 - 95,637,024 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129451   ⟹   ENSRNOP00000109055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1195,528,831 - 95,637,024 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000151189   ⟹   ENSRNOP00000111605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1195,528,831 - 95,636,281 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155365   ⟹   ENSRNOP00000110143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1195,528,831 - 95,633,939 (-)Ensembl
RefSeq Acc Id: NM_001135760   ⟹   NP_001129232
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81195,528,831 - 95,637,565 (-)NCBI
mRatBN7.21182,024,469 - 82,133,212 (-)NCBI
Rnor_6.01186,168,196 - 86,276,430 (-)NCBI
Rnor_5.01189,270,162 - 89,378,396 (-)NCBI
Celera1180,805,603 - 80,913,841 (-)RGD
Sequence:
RefSeq Acc Id: XM_063270678   ⟹   XP_063126748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81195,528,831 - 95,636,962 (-)NCBI
RefSeq Acc Id: XM_063270679   ⟹   XP_063126749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81195,528,831 - 95,636,962 (-)NCBI
RefSeq Acc Id: XM_063270680   ⟹   XP_063126750
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81195,528,831 - 95,633,644 (-)NCBI
RefSeq Acc Id: XM_063270681   ⟹   XP_063126751
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81195,528,831 - 95,636,883 (-)NCBI
RefSeq Acc Id: XM_063270682   ⟹   XP_063126752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81195,528,831 - 95,619,827 (-)NCBI
RefSeq Acc Id: XM_063270683   ⟹   XP_063126753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81195,528,831 - 95,618,004 (-)NCBI
RefSeq Acc Id: XR_010055965
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81195,552,752 - 95,636,962 (-)NCBI
RefSeq Acc Id: NP_001129232   ⟸   NM_001135760
- UniProtKB: M0R4R2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064357   ⟸   ENSRNOT00000075164
Ensembl Acc Id: ENSRNOP00000065274   ⟸   ENSRNOT00000071462
RefSeq Acc Id: XP_063126749   ⟸   XM_063270679
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063126748   ⟸   XM_063270678
- Peptide Label: isoform X1
- UniProtKB: M0R756 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126751   ⟸   XM_063270681
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063126750   ⟸   XM_063270680
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063126752   ⟸   XM_063270682
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063126753   ⟸   XM_063270683
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000110143   ⟸   ENSRNOT00000155365
Ensembl Acc Id: ENSRNOP00000109055   ⟸   ENSRNOT00000129451
Ensembl Acc Id: ENSRNOP00000098904   ⟸   ENSRNOT00000121679
Ensembl Acc Id: ENSRNOP00000111605   ⟸   ENSRNOT00000151189
Protein Domains
CAF1B/HIR1 beta-propeller   Protein HIRA-like C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R756-F1-model_v2 AlphaFold M0R756 1-1010 view protein structure
AF-M0R4R2-F1-model_v2 AlphaFold M0R4R2 1-1015 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698294
Promoter ID:EPDNEW_R8817
Type:multiple initiation site
Name:Hira_1
Description:histone cell cycle regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01186,275,971 - 86,276,031EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584950 AgrOrtholog
BioCyc Gene G2FUF-20678 BioCyc
Ensembl Genes ENSRNOG00000045770 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000049255 Ensembl
Ensembl Transcript ENSRNOT00000071462.4 UniProtKB/TrEMBL
  ENSRNOT00000075164 ENTREZGENE
  ENSRNOT00000075164.3 UniProtKB/TrEMBL
  ENSRNOT00000121679 ENTREZGENE
  ENSRNOT00000121679.1 UniProtKB/TrEMBL
  ENSRNOT00000129451 ENTREZGENE
  ENSRNOT00000129451.1 UniProtKB/TrEMBL
  ENSRNOT00000151189 ENTREZGENE
  ENSRNOT00000151189.1 UniProtKB/TrEMBL
  ENSRNOT00000155365.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro CAF1B_HIR1_beta-prop UniProtKB/TrEMBL
  HIR1 UniProtKB/TrEMBL
  Hira UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:363849 UniProtKB/TrEMBL
NCBI Gene 363849 ENTREZGENE
PANTHER PROTEIN HIRA UniProtKB/TrEMBL
  PTHR13831 UniProtKB/TrEMBL
Pfam Beta-prop_CAF1B_HIR1 UniProtKB/TrEMBL
  Hira UniProtKB/TrEMBL
PhenoGen Hira PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000045770 RatGTEx
  ENSRNOG00000049255 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0ABK0LB50_RAT UniProtKB/TrEMBL
  A0ABK0LH58_RAT UniProtKB/TrEMBL
  A0ABK0LUM4_RAT UniProtKB/TrEMBL
  A0ABK0LY86_RAT UniProtKB/TrEMBL
  M0R4R2 ENTREZGENE, UniProtKB/TrEMBL
  M0R756 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Hira  histone cell cycle regulator  LOC100911837  protein HIRA-like  Data merged from RGD:6490647 737654 PROVISIONAL
2013-09-16 Hira  histone cell cycle regulator  Hira  HIR histone cell cycle regulation defective homolog A (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911837  protein HIRA-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-12-01 Hira  HIR histone cell cycle regulation defective homolog A (S. cerevisiae)  LOC363849  similar to histone cell cycle regulation defective homolog A isoform 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC363849  similar to histone cell cycle regulation defective homolog A isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL