Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dtx3 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Dtx3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of DTX3 mRNA | CTD | PMID:22206623 | Dtx3 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Dtx3 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of DTX3 mRNA | CTD | PMID:17942748 | Dtx3 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of DTX3 mRNA | CTD | PMID:29097150 | Dtx3 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Dtx3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DTX3 mRNA | CTD | PMID:17942748 | Dtx3 | Rat | 17beta-estradiol | decreases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of DTX3 mRNA | CTD | PMID:31614463 | Dtx3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Dtx3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in increased expression of DTX3 mRNA; [Tetrachlorodibenzodioxin more ... | CTD | PMID:17942748|PMID:19465110 | Dtx3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DTX3 mRNA | CTD | PMID:34747641 | Dtx3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DTX3 mRNA | CTD | PMID:21296121 | Dtx3 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Dtx3 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of DTX3 mRNA | CTD | PMID:30047161 | Dtx3 | Rat | acrolein | multiple interactions | ISO | DTX3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in decreased expression of DTX3 mRNA | CTD | PMID:32845096 | Dtx3 | Rat | aflatoxin B1 | decreases methylation | ISO | DTX3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of DTX3 gene | CTD | PMID:27153756 | Dtx3 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of DTX3 mRNA | CTD | PMID:30047161 | Dtx3 | Rat | antirheumatic drug | increases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of DTX3 mRNA | CTD | PMID:24449571 | Dtx3 | Rat | benzo[a]pyrene | increases methylation | ISO | DTX3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of DTX3 promoter | CTD | PMID:27901495 | Dtx3 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of DTX3 mRNA | CTD | PMID:31163220 | Dtx3 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Dtx3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of DTX3 mRNA | CTD | PMID:33754040 | Dtx3 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of DTX3 mRNA | CTD | PMID:25181051 | Dtx3 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Dtx3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DTX3 mRNA | CTD | PMID:34947998 | Dtx3 | Rat | bisphenol F | decreases expression | ISO | Dtx3 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of DTX3 mRNA | CTD | PMID:38685157 | Dtx3 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Dtx3 | Rat | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of DTX3 mRNA | CTD | PMID:32479839 | Dtx3 | Rat | Butylbenzyl phthalate | increases expression | ISO | Dtx3 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased expression of DTX3 mRNA | CTD | PMID:28392331 | Dtx3 | Rat | cadmium dichloride | increases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of DTX3 mRNA | CTD | PMID:38568856 | Dtx3 | Rat | CGP 52608 | multiple interactions | ISO | DTX3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DTX3 gene] | CTD | PMID:28238834 | Dtx3 | Rat | chlordecone | decreases expression | ISO | Dtx3 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of DTX3 mRNA | CTD | PMID:33711761 | Dtx3 | Rat | chlorpyrifos | increases expression | ISO | Dtx3 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of DTX3 mRNA | CTD | PMID:37019170 | Dtx3 | Rat | choline | multiple interactions | ISO | Dtx3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Dtx3 | Rat | Dibutyl phosphate | affects expression | ISO | DTX3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of DTX3 mRNA | CTD | PMID:37042841 | Dtx3 | Rat | dorsomorphin | multiple interactions | ISO | DTX3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Dtx3 | Rat | doxorubicin | affects expression | ISO | DTX3 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of DTX3 mRNA | CTD | PMID:29803840 | Dtx3 | Rat | enzalutamide | affects expression | ISO | DTX3 (Homo sapiens) | 6480464 | enzalutamide affects the expression of DTX3 mRNA | CTD | PMID:30940724 | Dtx3 | Rat | ethanol | multiple interactions | ISO | Dtx3 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of DTX3 mRNA | CTD | PMID:30319688 | Dtx3 | Rat | folic acid | multiple interactions | ISO | Dtx3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Dtx3 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of DTX3 mRNA | CTD | PMID:33387578 | Dtx3 | Rat | glyphosate | increases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Glyphosate results in increased expression of DTX3 mRNA | CTD | PMID:31295307 | Dtx3 | Rat | hydrogen peroxide | affects expression | ISO | DTX3 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of DTX3 mRNA | CTD | PMID:20044591 | Dtx3 | Rat | hypochlorous acid | decreases expression | ISO | Dtx3 (Mus musculus) | 6480464 | Hypochlorous Acid results in decreased expression of DTX3 mRNA | CTD | PMID:19376150 | Dtx3 | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of DTX3 mRNA | CTD | PMID:21396975 | Dtx3 | Rat | L-methionine | multiple interactions | ISO | Dtx3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Dtx3 | Rat | methamphetamine | increases expression | ISO | Dtx3 (Mus musculus) | 6480464 | Methamphetamine results in increased expression of DTX3 mRNA | CTD | PMID:26307267 | Dtx3 | Rat | methamphetamine | increases methylation | ISO | Dtx3 (Mus musculus) | 6480464 | Methamphetamine results in increased methylation of DTX3 promoter | CTD | PMID:26307267 | Dtx3 | Rat | nickel atom | decreases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Nickel results in decreased expression of DTX3 mRNA | CTD | PMID:25583101 | Dtx3 | Rat | nickel sulfate | decreases expression | ISO | DTX3 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of DTX3 mRNA | CTD | PMID:22714537 | Dtx3 | Rat | ozone | multiple interactions | ISO | DTX3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in decreased expression of DTX3 mRNA | CTD | PMID:32845096 | Dtx3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Dtx3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of DTX3 mRNA | CTD | PMID:36331819 | Dtx3 | Rat | SB 431542 | multiple interactions | ISO | DTX3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Dtx3 | Rat | sodium arsenite | decreases expression | ISO | DTX3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of DTX3 mRNA | CTD | PMID:34032870 | Dtx3 | Rat | sodium arsenite | increases expression | ISO | DTX3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of DTX3 mRNA | CTD | PMID:39719251 | Dtx3 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of DTX3 mRNA | CTD | PMID:30047161 | Dtx3 | Rat | sunitinib | decreases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of DTX3 mRNA | CTD | PMID:31533062 | Dtx3 | Rat | temozolomide | decreases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of DTX3 mRNA | CTD | PMID:31758290 | Dtx3 | Rat | titanium dioxide | increases expression | ISO | Dtx3 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of DTX3 mRNA | CTD | PMID:29264374 | Dtx3 | Rat | valproic acid | decreases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DTX3 mRNA | CTD | PMID:23179753|PMID:26272509|PMID:28001369 | Dtx3 | Rat | valproic acid | multiple interactions | ISO | DTX3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Dtx3 | Rat | zinc sulfate | increases expression | ISO | DTX3 (Homo sapiens) | 6480464 | Zinc Sulfate results in increased expression of DTX3 mRNA | CTD | PMID:16330358 | Dtx3 | Rat | zoledronic acid | increases expression | ISO | DTX3 (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of DTX3 mRNA | CTD | PMID:20977926 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















