DTX3 (deltex E3 ubiquitin ligase 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: DTX3 (deltex E3 ubiquitin ligase 3) Homo sapiens
Analyze
Symbol: DTX3
Name: deltex E3 ubiquitin ligase 3
RGD ID: 1347578
HGNC Page HGNC:24457
Description: Predicted to enable ligase activity; metal ion binding activity; and ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within Notch signaling pathway. Predicted to be located in cytoplasm and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: deltex 3 homolog; deltex 3, E3 ubiquitin ligase; deltex homolog 3; deltex3; FLJ34766; MGC138863; MGC138864; probable E3 ubiquitin-protein ligase DTX3; protein deltex-3; RING finger protein 154; RING-type E3 ubiquitin transferase DTX3; RNF154
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,604,824 - 57,609,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,604,622 - 57,609,804 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,998,607 - 58,003,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,284,871 - 56,289,850 (+)NCBINCBI36Build 36hg18NCBI36
Build 341256,284,870 - 56,289,850NCBI
Celera1257,654,419 - 57,659,398 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1255,036,290 - 55,041,268 (+)NCBIHuRef
CHM1_11257,966,420 - 57,971,399 (+)NCBICHM1_1
T2T-CHM13v2.01257,572,308 - 57,578,021 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7671825   PMID:11226752   PMID:12477932   PMID:12670957   PMID:14702039   PMID:16344560   PMID:17028573   PMID:19549727   PMID:21873635   PMID:22493164   PMID:23105109   PMID:23503679  
PMID:24705354   PMID:25416956   PMID:26186194   PMID:28514442   PMID:28986522   PMID:29643511   PMID:31854042   PMID:32296183   PMID:32814053   PMID:33403043   PMID:33616774   PMID:33961781  
PMID:35563538   PMID:35782979   PMID:36614304   PMID:37108544  


Genomics

Comparative Map Data
DTX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,604,824 - 57,609,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,604,622 - 57,609,804 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,998,607 - 58,003,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,284,871 - 56,289,850 (+)NCBINCBI36Build 36hg18NCBI36
Build 341256,284,870 - 56,289,850NCBI
Celera1257,654,419 - 57,659,398 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1255,036,290 - 55,041,268 (+)NCBIHuRef
CHM1_11257,966,420 - 57,971,399 (+)NCBICHM1_1
T2T-CHM13v2.01257,572,308 - 57,578,021 (+)NCBIT2T-CHM13v2.0
Dtx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,026,242 - 127,032,367 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,026,247 - 127,031,597 (-)EnsemblGRCm39 Ensembl
GRCm3810127,190,373 - 127,196,498 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,190,378 - 127,195,728 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,627,434 - 126,632,765 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,593,327 - 126,598,658 (-)NCBIMGSCv36mm8
Celera10129,583,408 - 129,588,773 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Dtx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,898,693 - 64,904,636 (-)NCBIGRCr8
mRatBN7.2763,013,769 - 63,018,431 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,013,371 - 63,018,522 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,903,070 - 64,907,731 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,105,474 - 67,110,135 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,906,542 - 66,911,203 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,476,737 - 70,482,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,476,729 - 70,481,796 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,654,378 - 70,660,222 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,145,276 - 67,149,937 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera760,155,333 - 60,160,117 (-)NCBICelera
Cytogenetic Map7q22NCBI
Dtx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,328,725 - 5,334,092 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,328,723 - 5,334,092 (+)NCBIChiLan1.0ChiLan1.0
DTX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,731,185 - 36,734,797 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,727,956 - 36,731,568 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,316,968 - 31,322,340 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,576,351 - 31,581,819 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,577,001 - 31,579,669 (-)Ensemblpanpan1.1panPan2
DTX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,684,394 - 1,687,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,683,410 - 1,686,814 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,745,460 - 1,750,402 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,691,642 - 1,696,581 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,691,625 - 1,696,579 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,669,425 - 1,674,360 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,911,185 - 1,916,104 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0102,036,415 - 2,041,352 (+)NCBIUU_Cfam_GSD_1.0
Dtx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,115,836 - 57,121,204 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,751,387 - 1,754,353 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,749,061 - 1,754,399 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DTX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,867,711 - 22,873,393 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,867,691 - 22,873,413 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,734,097 - 24,820,351 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DTX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,512,657 - 53,517,978 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,515,043 - 53,517,330 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,444,161 - 192,449,230 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dtx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,354,077 - 10,359,769 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,353,488 - 10,359,690 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DTX3
10 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12q13.3-14.2(chr12:57013355-63042498)x1 copy number loss See cases [RCV000052813] Chr12:57013355..63042498 [GRCh38]
Chr12:57407139..63436278 [GRCh37]
Chr12:55693406..61722545 [NCBI36]
Chr12:12q13.3-14.2		 pathogenic
GRCh38/hg38 12q13.3-14.1(chr12:57041158-60273934)x1 copy number loss See cases [RCV000052814] Chr12:57041158..60273934 [GRCh38]
Chr12:57434942..60667715 [GRCh37]
Chr12:55721209..58953982 [NCBI36]
Chr12:12q13.3-14.1		 pathogenic
PIP4K2C:c.1090C>T single nucleotide variant Malignant melanoma [RCV000070145] Chr12:57601253 [GRCh38]
Chr12:57995036 [GRCh37]
Chr12:56281303 [NCBI36]
Chr12:12q13.3		 not provided
NM_001111270.2(ARHGEF25):c.371C>T (p.Ser124Phe) single nucleotide variant Malignant melanoma [RCV000062572] Chr12:57613086 [GRCh38]
Chr12:58006869 [GRCh37]
Chr12:56293136 [NCBI36]
Chr12:12q13.3		 not provided
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic|likely pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12q13.3-14.1(chr12:57582163-59031979)x1 copy number loss not provided [RCV001006506] Chr12:57582163..59031979 [GRCh37]
Chr12:12q13.3-14.1		 likely pathogenic
GRCh37/hg19 12q13.2-14.1(chr12:55552371-62126304)x3 copy number gain not provided [RCV001006505] Chr12:55552371..62126304 [GRCh37]
Chr12:12q13.2-14.1		 pathogenic
NC_000012.11:g.(?_57881874)_(58190366_?)dup duplication not provided [RCV001916382] Chr12:57881874..58190366 [GRCh37]
Chr12:12q13.3-14.1		 uncertain significance
NC_000012.11:g.(?_57971476)_(58025915_?)dup duplication Spastic paraplegia [RCV003113623] Chr12:57971476..58025915 [GRCh37]
Chr12:12q13.3		 uncertain significance
NC_000012.11:g.(?_57534470)_(58190366_?)dup duplication Familial melanoma [RCV003119257] Chr12:57534470..58190366 [GRCh37]
Chr12:12q13.3-14.1		 uncertain significance
GRCh37/hg19 12q13.3-14.1(chr12:57631073-58236597)x1 copy number loss not provided [RCV002474565] Chr12:57631073..58236597 [GRCh37]
Chr12:12q13.3-14.1		 likely pathogenic
NM_178502.4(DTX3):c.206C>G (p.Pro69Arg) single nucleotide variant not specified [RCV004189907] Chr12:57607069 [GRCh38]
Chr12:58000852 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.358G>A (p.Ala120Thr) single nucleotide variant not specified [RCV004108519] Chr12:57607221 [GRCh38]
Chr12:58001004 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.297G>C (p.Gln99His) single nucleotide variant not specified [RCV004135377] Chr12:57607160 [GRCh38]
Chr12:58000943 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.122G>A (p.Arg41Gln) single nucleotide variant not specified [RCV004215593] Chr12:57606985 [GRCh38]
Chr12:58000768 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.454C>T (p.Arg152Cys) single nucleotide variant not specified [RCV004181824] Chr12:57607317 [GRCh38]
Chr12:58001100 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.985C>T (p.Pro329Ser) single nucleotide variant not specified [RCV004185058] Chr12:57609093 [GRCh38]
Chr12:58002876 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.10G>C (p.Val4Leu) single nucleotide variant not specified [RCV004125761] Chr12:57606873 [GRCh38]
Chr12:58000656 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.304C>G (p.Leu102Val) single nucleotide variant not specified [RCV004269807] Chr12:57607167 [GRCh38]
Chr12:58000950 [GRCh37]
Chr12:12q13.3		 uncertain significance
GRCh37/hg19 12q13.3-14.1(chr12:57064059-59314016)x1 copy number loss not provided [RCV003222783] Chr12:57064059..59314016 [GRCh37]
Chr12:12q13.3-14.1		 likely pathogenic
NM_178502.4(DTX3):c.418C>G (p.Pro140Ala) single nucleotide variant not specified [RCV004350846] Chr12:57607281 [GRCh38]
Chr12:58001064 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.440C>T (p.Pro147Leu) single nucleotide variant not specified [RCV004339254] Chr12:57607303 [GRCh38]
Chr12:58001086 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.424C>T (p.Pro142Ser) single nucleotide variant not specified [RCV004379516] Chr12:57607287 [GRCh38]
Chr12:58001070 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.592G>T (p.Ala198Ser) single nucleotide variant not specified [RCV004379517] Chr12:57607455 [GRCh38]
Chr12:58001238 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.727G>A (p.Val243Ile) single nucleotide variant not specified [RCV004379518] Chr12:57607590 [GRCh38]
Chr12:58001373 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.239A>G (p.Lys80Arg) single nucleotide variant not specified [RCV004379514] Chr12:57607102 [GRCh38]
Chr12:58000885 [GRCh37]
Chr12:12q13.3		 uncertain significance
NM_178502.4(DTX3):c.406C>T (p.Arg136Trp) single nucleotide variant not specified [RCV004379515] Chr12:57607269 [GRCh38]
Chr12:58001052 [GRCh37]
Chr12:12q13.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3560
Count of miRNA genes:764
Interacting mature miRNAs:901
Transcripts:ENST00000337737, ENST00000548198, ENST00000548478, ENST00000548804, ENST00000549583, ENST00000550300, ENST00000550596, ENST00000551632, ENST00000551835
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-148470  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371257,998,787 - 57,999,096UniSTSGRCh37
Build 361256,285,054 - 56,285,363RGDNCBI36
Celera1257,654,602 - 57,654,911RGD
Cytogenetic Map12q13.3UniSTS
HuRef1255,036,473 - 55,036,782UniSTS
TNG Radiation Hybrid Map1227371.0UniSTS
DTX3__4788  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371258,002,919 - 58,003,764UniSTSGRCh37
Build 361256,289,186 - 56,290,031RGDNCBI36
Celera1257,658,734 - 57,659,579RGD
HuRef1255,040,604 - 55,041,449UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 3
Medium 2147 2222 1298 189 1112 40 3185 1340 3663 325 1401 1540 157 1031 1856 1
Low 227 737 424 430 747 420 1168 851 64 80 49 62 17 1 173 932 3
Below cutoff 20 29 2 3 59 4 2 3 3 9 6 7 1 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001286245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_178502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005268697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005268698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005268700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005268703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011538022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054371386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC022506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC025165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK092085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL831941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY225126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC114441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC114498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA684401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MH536518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000337737   ⟹   ENSP00000338050
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,604,824 - 57,609,802 (+)Ensembl
RefSeq Acc Id: ENST00000548198   ⟹   ENSP00000447873
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,604,824 - 57,609,803 (+)Ensembl
RefSeq Acc Id: ENST00000548478   ⟹   ENSP00000448224
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,605,007 - 57,607,466 (+)Ensembl
RefSeq Acc Id: ENST00000548804   ⟹   ENSP00000449294
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,604,622 - 57,609,800 (+)Ensembl
RefSeq Acc Id: ENST00000549583   ⟹   ENSP00000449688
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,604,639 - 57,607,467 (+)Ensembl
RefSeq Acc Id: ENST00000550300   ⟹   ENSP00000446996
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,607,500 - 57,609,196 (+)Ensembl
RefSeq Acc Id: ENST00000550596   ⟹   ENSP00000449118
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,604,623 - 57,606,511 (+)Ensembl
RefSeq Acc Id: ENST00000551632   ⟹   ENSP00000448696
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,604,834 - 57,609,804 (+)Ensembl
RefSeq Acc Id: ENST00000551835   ⟹   ENSP00000449950
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1257,604,623 - 57,607,009 (+)Ensembl
RefSeq Acc Id: NM_001286245   ⟹   NP_001273174
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
HuRef1255,036,091 - 55,041,272 (+)NCBI
CHM1_11257,966,221 - 57,971,403 (+)NCBI
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001286246   ⟹   NP_001273175
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
HuRef1255,036,091 - 55,041,272 (+)NCBI
CHM1_11257,966,221 - 57,971,403 (+)NCBI
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
Sequence:
RefSeq Acc Id: NM_178502   ⟹   NP_848597
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
GRCh371257,998,110 - 58,003,585 (+)NCBI
Build 361256,284,871 - 56,289,850 (+)NCBI Archive
Celera1257,654,419 - 57,659,398 (+)RGD
HuRef1255,036,091 - 55,041,272 (+)NCBI
CHM1_11257,966,221 - 57,971,403 (+)NCBI
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005268697   ⟹   XP_005268754
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005268698   ⟹   XP_005268755
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
GRCh371257,998,110 - 58,003,585 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005268700   ⟹   XP_005268757
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
GRCh371257,998,110 - 58,003,585 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005268703   ⟹   XP_005268760
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
GRCh371257,998,110 - 58,003,585 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011538022   ⟹   XP_011536324
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448876   ⟹   XP_024304644
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047428479   ⟹   XP_047284435
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
RefSeq Acc Id: XM_047428480   ⟹   XP_047284436
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
RefSeq Acc Id: XM_047428481   ⟹   XP_047284437
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
RefSeq Acc Id: XM_047428482   ⟹   XP_047284438
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,605,738 - 57,609,802 (+)NCBI
RefSeq Acc Id: XM_047428483   ⟹   XP_047284439
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
RefSeq Acc Id: XM_047428484   ⟹   XP_047284440
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,609,802 (+)NCBI
RefSeq Acc Id: XM_054371378   ⟹   XP_054227353
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,572,308 - 57,578,021 (+)NCBI
RefSeq Acc Id: XM_054371379   ⟹   XP_054227354
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
RefSeq Acc Id: XM_054371380   ⟹   XP_054227355
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
RefSeq Acc Id: XM_054371381   ⟹   XP_054227356
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
RefSeq Acc Id: XM_054371382   ⟹   XP_054227357
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,573,957 - 57,578,021 (+)NCBI
RefSeq Acc Id: XM_054371383   ⟹   XP_054227358
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
RefSeq Acc Id: XM_054371384   ⟹   XP_054227359
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
RefSeq Acc Id: XM_054371385   ⟹   XP_054227360
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
RefSeq Acc Id: XM_054371386   ⟹   XP_054227361
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01257,573,043 - 57,578,021 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001273174 (Get FASTA)   NCBI Sequence Viewer  
  NP_001273175 (Get FASTA)   NCBI Sequence Viewer  
  NP_848597 (Get FASTA)   NCBI Sequence Viewer  
  XP_005268754 (Get FASTA)   NCBI Sequence Viewer  
  XP_005268755 (Get FASTA)   NCBI Sequence Viewer  
  XP_005268757 (Get FASTA)   NCBI Sequence Viewer  
  XP_005268760 (Get FASTA)   NCBI Sequence Viewer  
  XP_011536324 (Get FASTA)   NCBI Sequence Viewer  
  XP_024304644 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284435 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284436 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284437 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284438 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284439 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284440 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227353 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227354 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227355 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227356 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227357 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227358 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227359 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227360 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227361 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI14442 (Get FASTA)   NCBI Sequence Viewer  
  AAI14499 (Get FASTA)   NCBI Sequence Viewer  
  AAP57520 (Get FASTA)   NCBI Sequence Viewer  
  AXL48294 (Get FASTA)   NCBI Sequence Viewer  
  BAC03801 (Get FASTA)   NCBI Sequence Viewer  
  BAC04344 (Get FASTA)   NCBI Sequence Viewer  
  BAG54727 (Get FASTA)   NCBI Sequence Viewer  
  CAD38593 (Get FASTA)   NCBI Sequence Viewer  
  EAW97032 (Get FASTA)   NCBI Sequence Viewer  
  EAW97033 (Get FASTA)   NCBI Sequence Viewer  
  EAW97034 (Get FASTA)   NCBI Sequence Viewer  
  EAW97035 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000338050
  ENSP00000338050.3
  ENSP00000446996.1
  ENSP00000447873
  ENSP00000447873.1
  ENSP00000448224.1
  ENSP00000448696
  ENSP00000448696.1
  ENSP00000449118.1
  ENSP00000449294
  ENSP00000449294.1
  ENSP00000449688.1
  ENSP00000449950.1
GenBank Protein Q8N9I9 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_848597   ⟸   NM_178502
- Peptide Label: isoform a
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005268754   ⟸   XM_005268697
- Peptide Label: isoform X1
- UniProtKB: Q8N9I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005268755   ⟸   XM_005268698
- Peptide Label: isoform X1
- UniProtKB: Q8N9I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005268760   ⟸   XM_005268703
- Peptide Label: isoform X2
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005268757   ⟸   XM_005268700
- Peptide Label: isoform X1
- UniProtKB: Q8N9I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001273175   ⟸   NM_001286246
- Peptide Label: isoform a
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001273174   ⟸   NM_001286245
- Peptide Label: isoform b
- UniProtKB: Q8N9I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011536324   ⟸   XM_011538022
- Peptide Label: isoform X2
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_024304644   ⟸   XM_024448876
- Peptide Label: isoform X2
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000338050   ⟸   ENST00000337737
RefSeq Acc Id: ENSP00000449294   ⟸   ENST00000548804
RefSeq Acc Id: ENSP00000448224   ⟸   ENST00000548478
RefSeq Acc Id: ENSP00000447873   ⟸   ENST00000548198
RefSeq Acc Id: ENSP00000449688   ⟸   ENST00000549583
RefSeq Acc Id: ENSP00000446996   ⟸   ENST00000550300
RefSeq Acc Id: ENSP00000449118   ⟸   ENST00000550596
RefSeq Acc Id: ENSP00000448696   ⟸   ENST00000551632
RefSeq Acc Id: ENSP00000449950   ⟸   ENST00000551835
RefSeq Acc Id: XP_047284436   ⟸   XM_047428480
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047284440   ⟸   XM_047428484
- Peptide Label: isoform X2
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_047284435   ⟸   XM_047428479
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047284439   ⟸   XM_047428483
- Peptide Label: isoform X2
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_047284437   ⟸   XM_047428481
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047284438   ⟸   XM_047428482
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054227353   ⟸   XM_054371378
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054227360   ⟸   XM_054371385
- Peptide Label: isoform X2
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054227359   ⟸   XM_054371384
- Peptide Label: isoform X2
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054227354   ⟸   XM_054371379
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054227355   ⟸   XM_054371380
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054227356   ⟸   XM_054371381
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054227361   ⟸   XM_054371386
- Peptide Label: isoform X2
- UniProtKB: Q8NAU6 (UniProtKB/Swiss-Prot),   Q8N9I9 (UniProtKB/Swiss-Prot),   Q53ZZ2 (UniProtKB/Swiss-Prot),   Q8NDS8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054227358   ⟸   XM_054371383
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054227357   ⟸   XM_054371382
- Peptide Label: isoform X1
Protein Domains
Deltex C-terminal   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8N9I9-F1-model_v2 AlphaFold Q8N9I9 1-347 view protein structure

Promoters
RGD ID:6789876
Promoter ID:HG_KWN:15988
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid
Transcripts:NM_178502,   UC001SOV.1,   UC001SOX.1,   UC001SOY.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361256,284,716 - 56,285,227 (+)MPROMDB
RGD ID:7224573
Promoter ID:EPDNEW_H18033
Type:initiation region
Name:DTX3_2
Description:deltex E3 ubiquitin ligase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18034  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,609 - 57,604,669EPDNEW
RGD ID:7224577
Promoter ID:EPDNEW_H18034
Type:multiple initiation site
Name:DTX3_1
Description:deltex E3 ubiquitin ligase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18033  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381257,604,824 - 57,604,884EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:24457 AgrOrtholog
COSMIC DTX3 COSMIC
Ensembl Genes ENSG00000178498 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000337737 ENTREZGENE
  ENST00000337737.8 UniProtKB/Swiss-Prot
  ENST00000548198 ENTREZGENE
  ENST00000548198.5 UniProtKB/Swiss-Prot
  ENST00000548478.1 UniProtKB/TrEMBL
  ENST00000548804 ENTREZGENE
  ENST00000548804.5 UniProtKB/Swiss-Prot
  ENST00000549583.5 UniProtKB/TrEMBL
  ENST00000550300.1 UniProtKB/TrEMBL
  ENST00000550596.5 UniProtKB/TrEMBL
  ENST00000551632 ENTREZGENE
  ENST00000551632.1 UniProtKB/Swiss-Prot
  ENST00000551835.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.390.130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000178498 GTEx
HGNC ID HGNC:24457 ENTREZGENE
Human Proteome Map DTX3 Human Proteome Map
InterPro Deltex_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Deltex_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Deltex_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:196403 UniProtKB/Swiss-Prot
NCBI Gene 196403 ENTREZGENE
OMIM 613142 OMIM
PANTHER E3 UBIQUITIN-PROTEIN LIGASE DTX3-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12622 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DTC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C3HC4_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134887936 PharmGKB
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0C4DGI8_HUMAN UniProtKB/TrEMBL
  A0A1Y8EH36_HUMAN UniProtKB/TrEMBL
  A0A346B4X6_HUMAN UniProtKB/TrEMBL
  DTX3_HUMAN UniProtKB/Swiss-Prot
  F8VUZ4_HUMAN UniProtKB/TrEMBL
  F8VV96_HUMAN UniProtKB/TrEMBL
  H0YHF9_HUMAN UniProtKB/TrEMBL
  Q53ZZ2 ENTREZGENE
  Q8N9I9 ENTREZGENE
  Q8NAU6 ENTREZGENE
  Q8NDS8 ENTREZGENE
UniProt Secondary Q53ZZ2 UniProtKB/Swiss-Prot
  Q8NAU6 UniProtKB/Swiss-Prot
  Q8NDS8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-21 DTX3  deltex E3 ubiquitin ligase 3  DTX3  deltex 3, E3 ubiquitin ligase  Symbol and/or name change 5135510 APPROVED
2014-02-04 DTX3  deltex 3, E3 ubiquitin ligase  DTX3  deltex homolog 3 (Drosophila)  Symbol and/or name change 5135510 APPROVED