Heatr1 (HEAT repeat containing 1) - Rat Genome Database

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Gene: Heatr1 (HEAT repeat containing 1) Rattus norvegicus
Analyze
Symbol: Heatr1
Name: HEAT repeat containing 1
RGD ID: 1564769
Description: Predicted to enable snoRNA binding activity. Predicted to be involved in several processes, including maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of RNA metabolic process; and protein localization to nucleolus. Predicted to be located in nucleolus. Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in pancreatic ductal carcinoma. Orthologous to human HEATR1 (HEAT repeat containing 1); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HEAT repeat containing 1-like 1; HEAT repeat-containing protein 1; Heatr1l1; LOC108348069; LOC361262; RGD1564769; similar to BAP28 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81762,745,008 - 62,785,609 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1762,745,008 - 62,785,186 (-)EnsemblGRCr8
mRatBN7.21758,053,288 - 58,093,895 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1758,051,700 - 58,093,948 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1761,242,806 - 61,283,163 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01765,245,917 - 65,286,278 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01759,400,119 - 59,440,480 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01766,446,135 - 66,488,303 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1766,446,162 - 66,619,250 (+)Ensemblrn6Rnor6.0
Rnor_5.01768,191,902 - 68,234,059 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41768,613,162 - 68,654,896 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1762,440,337 - 62,481,984 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
dibenz[a,h]anthracene  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folpet  (ISO)
formaldehyde  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
inulin  (ISO)
ivermectin  (ISO)
menadione  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nitrates  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. HEATR1 Negatively Regulates Akt to Help Sensitize Pancreatic Cancer Cells to Chemotherapy. Liu T, etal., Cancer Res. 2016 Feb 1;76(3):572-81. doi: 10.1158/0008-5472.CAN-15-0671. Epub 2015 Dec 16.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Glioma-associated antigen HEATR1 induces functional cytotoxic T lymphocytes in patients with glioma. Wu ZB, etal., J Immunol Res. 2014;2014:131494. doi: 10.1155/2014/131494. Epub 2014 Jul 9.
Additional References at PubMed
PMID:17699751   PMID:19946888   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Heatr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81762,745,008 - 62,785,609 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1762,745,008 - 62,785,186 (-)EnsemblGRCr8
mRatBN7.21758,053,288 - 58,093,895 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1758,051,700 - 58,093,948 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1761,242,806 - 61,283,163 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01765,245,917 - 65,286,278 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01759,400,119 - 59,440,480 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01766,446,135 - 66,488,303 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1766,446,162 - 66,619,250 (+)Ensemblrn6Rnor6.0
Rnor_5.01768,191,902 - 68,234,059 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41768,613,162 - 68,654,896 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1762,440,337 - 62,481,984 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
HEATR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381236,549,005 - 236,604,516 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1236,549,005 - 236,604,516 (-)Ensemblhg38GRCh38
GRCh371236,712,305 - 236,767,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361234,780,594 - 234,834,437 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1209,960,588 - 210,016,126 (-)NCBICelera
Cytogenetic Map1q43NCBI
HuRef1207,169,321 - 207,224,840 (-)NCBIHuRef
CHM1_11237,985,198 - 238,040,643 (-)NCBICHM1_1
T2T-CHM13v2.01235,949,959 - 236,005,476 (-)NCBIT2T-CHM13v2.0
Heatr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391312,410,256 - 12,453,774 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1312,409,908 - 12,455,170 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381312,395,375 - 12,438,893 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1312,395,027 - 12,440,289 (+)Ensemblmm10GRCm38
MGSCv371312,487,642 - 12,531,160 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361312,449,708 - 12,493,226 (+)NCBIMGSCv36mm8
Celera1312,311,864 - 12,355,146 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map134.56NCBI
Heatr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554923,627,889 - 3,672,269 (+)Ensembl
ChiLan1.0NW_0049554923,627,889 - 3,672,269 (+)NCBIChiLan1.0ChiLan1.0
HEATR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,581,348 - 12,635,455 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,793,437 - 12,847,301 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01212,110,229 - 212,164,299 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11217,109,359 - 217,164,794 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1217,109,359 - 217,164,791 (-)EnsemblpanPan2panpan1.1
HEATR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.143,501,191 - 3,547,212 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl43,501,571 - 3,547,100 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha43,547,564 - 3,593,598 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.043,521,595 - 3,567,840 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl43,521,651 - 3,567,834 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.143,534,410 - 3,580,650 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.043,651,290 - 3,697,540 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.043,871,796 - 3,917,820 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Heatr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934440,146,286 - 40,190,751 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648416,312,223 - 16,357,099 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648416,310,766 - 16,355,977 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEATR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1454,821,171 - 54,869,857 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11454,821,073 - 54,870,873 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21458,794,708 - 58,843,358 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HEATR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12573,684,845 - 73,743,594 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2573,685,895 - 73,743,654 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605575,774,282 - 75,836,312 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Heatr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477514,047,985 - 14,094,438 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477514,047,970 - 14,095,356 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Heatr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11426,143,783 - 26,184,468 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Heatr1
234 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:225
Count of miRNA genes:140
Interacting mature miRNAs:149
Transcripts:ENSRNOT00000070825, ENSRNOT00000071829
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174949693265155015Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)173006647275066472Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)173310464578104645Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172328632264246472Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)172652205171522051Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)173544694975762341Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172201970567019705Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)173310464578104645Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)176109144668550213Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172385892668858926Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172385892668858926Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172723344565155015Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172723344572233445Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172385892668858926Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172385892668858926Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172385892668858926Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat

Markers in Region
RH124435  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21758,058,060 - 58,058,338 (-)MAPPERmRatBN7.2
Rnor_6.01766,614,415 - 66,614,692NCBIRnor6.0
Rnor_6.01766,481,665 - 66,481,942NCBIRnor6.0
Rnor_5.01768,227,421 - 68,227,698UniSTSRnor5.0
Rnor_5.01768,357,444 - 68,357,721UniSTSRnor5.0
RGSC_v3.41768,619,523 - 68,619,800UniSTSRGSC3.4
Celera1762,475,347 - 62,475,624UniSTS
Cytogenetic Map17q12.1UniSTS
RH133085  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X77,848,602 - 77,848,801NCBIRnor5.0
Rnor_5.01768,233,390 - 68,233,588NCBIRnor5.0
RGSC_v3.41768,613,633 - 68,613,830UniSTSRGSC3.4
RGSC_v3.4X94,781,342 - 94,781,540UniSTSRGSC3.4
Celera1762,481,316 - 62,481,513UniSTS
CeleraX72,954,475 - 72,954,673UniSTS
RH 3.4 Map17610.79UniSTS
Cytogenetic MapXq31UniSTS
Cytogenetic Map17q12.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 6 55 163 80 79 48 92 48 6 322 177 11 142 76 91 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000070825   ⟹   ENSRNOP00000064012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1762,745,008 - 62,785,186 (-)Ensembl
mRatBN7.2 Ensembl1758,051,700 - 58,093,948 (-)Ensembl
Rnor_6.0 Ensembl1766,446,569 - 66,486,500 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000071829   ⟹   ENSRNOP00000065894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1762,745,008 - 62,785,186 (-)Ensembl
mRatBN7.2 Ensembl1758,051,700 - 58,093,948 (-)Ensembl
Rnor_6.0 Ensembl1766,579,319 - 66,619,250 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000078906   ⟹   ENSRNOP00000069390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1766,446,162 - 66,613,839 (+)Ensembl
RefSeq Acc Id: NM_001108418   ⟹   NP_001101888
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81762,745,008 - 62,785,186 (-)NCBI
mRatBN7.21758,053,288 - 58,093,466 (-)NCBI
Rnor_6.01766,446,569 - 66,488,303 (+)NCBI
Rnor_5.01768,191,902 - 68,234,059 (+)NCBI
RGSC_v3.41768,613,162 - 68,654,896 (-)RGD
Celera1762,440,337 - 62,481,984 (+)RGD
Sequence:
RefSeq Acc Id: XM_017600630   ⟹   XP_017456119
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81762,745,008 - 62,785,609 (-)NCBI
mRatBN7.21758,053,410 - 58,093,895 (-)NCBI
Rnor_6.01766,446,135 - 66,486,715 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600631   ⟹   XP_017456120
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81762,745,008 - 62,785,599 (-)NCBI
mRatBN7.21758,053,410 - 58,093,884 (-)NCBI
Rnor_6.01766,446,135 - 66,486,715 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001101888 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456119 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456120 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM06984 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064012
  ENSRNOP00000064012.3
  ENSRNOP00000065894.4
RefSeq Acc Id: NP_001101888   ⟸   NM_001108418
- UniProtKB: M0R3U0 (UniProtKB/TrEMBL),   A6KN33 (UniProtKB/TrEMBL),   D3ZL86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456120   ⟸   XM_017600631
- Peptide Label: isoform X1
- UniProtKB: M0R3U0 (UniProtKB/TrEMBL),   A6KN33 (UniProtKB/TrEMBL),   D3ZL86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456119   ⟸   XM_017600630
- Peptide Label: isoform X1
- UniProtKB: M0R3U0 (UniProtKB/TrEMBL),   A6KN33 (UniProtKB/TrEMBL),   D3ZL86 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064012   ⟸   ENSRNOT00000070825
Ensembl Acc Id: ENSRNOP00000065894   ⟸   ENSRNOT00000071829
Ensembl Acc Id: ENSRNOP00000069390   ⟸   ENSRNOT00000078906
Protein Domains
BP28 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZL86-F1-model_v2 AlphaFold D3ZL86 1-2143 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564769 AgrOrtholog
BioCyc Gene G2FUF-8938 BioCyc
Ensembl Genes ENSRNOG00000047594 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000070825 ENTREZGENE
  ENSRNOT00000070825.4 UniProtKB/TrEMBL
  ENSRNOT00000071829.4 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  BP28_C_dom UniProtKB/TrEMBL
  HEAT_Utp10/HEAT1 UniProtKB/TrEMBL
  U3snoRNP10 UniProtKB/TrEMBL
  UTP10 UniProtKB/TrEMBL
KEGG Report rno:361262 UniProtKB/TrEMBL
NCBI Gene 361262 ENTREZGENE
PANTHER HEAT REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR13457 UniProtKB/TrEMBL
Pfam BP28CT UniProtKB/TrEMBL
  HEAT_HEATR1 UniProtKB/TrEMBL
  U3snoRNP10 UniProtKB/TrEMBL
PhenoGen Heatr1 PhenoGen
RatGTEx ENSRNOG00000047594 RatGTEx
SMART BP28CT UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A6KN33 ENTREZGENE, UniProtKB/TrEMBL
  D3ZL86 ENTREZGENE, UniProtKB/TrEMBL
  M0R3U0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Heatr1  HEAT repeat containing 1  LOC108348069  HEAT repeat-containing protein 1  Data merged from RGD:11474378 737654 PROVISIONAL
2016-08-02 LOC108348069  HEAT repeat-containing protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Heatr1  HEAT repeat containing 1   Heatr1_predicted  HEAT repeat containing 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Heatr1_predicted  HEAT repeat containing 1 (predicted)  RGD1564769_predicted  similar to BAP28 protein (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1564769_predicted  similar to BAP28 protein (predicted)  LOC361262  similar to BAP28 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC361262  similar to BAP28 protein      Symbol and Name status set to provisional 70820 PROVISIONAL