Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Map3k13 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MAP3K13 mRNA] | CTD | PMID:31150632 | Map3k13 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of MAP3K13 mRNA | CTD | PMID:32145629 | Map3k13 | Rat | 17beta-estradiol | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Estradiol results in decreased expression of MAP3K13 mRNA | CTD | PMID:39298647 | Map3k13 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MAP3K13 mRNA | CTD | PMID:26290441 | Map3k13 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MAP3K13 mRNA | CTD | PMID:33387578 | Map3k13 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Map3k13 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of MAP3K13 mRNA | CTD | PMID:20188158 | Map3k13 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of MAP3K13 mRNA | CTD | PMID:39298647 | Map3k13 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | MAP3K13 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of MAP3K13 gene | CTD | PMID:31601247 | Map3k13 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of MAP3K13 mRNA | CTD | PMID:24780913 | Map3k13 | Rat | acrylamide | increases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of MAP3K13 mRNA | CTD | PMID:32763439 | Map3k13 | Rat | aflatoxin B1 | affects expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of MAP3K13 protein | CTD | PMID:20106945 | Map3k13 | Rat | aflatoxin B1 | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of MAP3K13 mRNA | CTD | PMID:22100608 | Map3k13 | Rat | aldehydo-D-glucose | multiple interactions | ISO | Map3k13 (Mus musculus) | 6480464 | fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAP3K13 mRNA] | CTD | PMID:33448797 | Map3k13 | Rat | aldehydo-D-glucose | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Glucose results in decreased expression of MAP3K13 mRNA | CTD | PMID:33448797 | Map3k13 | Rat | aldehydo-D-glucose | increases methylation | ISO | Map3k13 (Mus musculus) | 6480464 | Glucose results in increased methylation of MAP3K13 gene | CTD | PMID:33448797 | Map3k13 | Rat | all-trans-retinoic acid | increases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of MAP3K13 mRNA | CTD | PMID:33167477 | Map3k13 | Rat | all-trans-retinoic acid | increases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Tretinoin results in increased expression of MAP3K13 mRNA | CTD | PMID:36189433 | Map3k13 | Rat | all-trans-retinoic acid | multiple interactions | ISO | Map3k13 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAP3K13 mRNA | CTD | PMID:36189433 | Map3k13 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MAP3K13 mRNA | CTD | PMID:35163327 | Map3k13 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of MAP3K13 mRNA | CTD | PMID:30047161 | Map3k13 | Rat | antirheumatic drug | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of MAP3K13 mRNA | CTD | PMID:24449571 | Map3k13 | Rat | antirheumatic drug | affects expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Antirheumatic Agents affects the expression of MAP3K13 mRNA | CTD | PMID:24449571 | Map3k13 | Rat | atrazine | increases expression | EXP | | 6480464 | Atrazine results in increased expression of MAP3K13 mRNA | CTD | PMID:36841081 | Map3k13 | Rat | benzo[a]pyrene | affects methylation | ISO | MAP3K13 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MAP3K13 promoter | CTD | PMID:27901495 | Map3k13 | Rat | benzo[a]pyrene | increases methylation | ISO | Map3k13 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of MAP3K13 exon; Benzo(a)pyrene results in increased methylation of MAP3K13 more ... | CTD | PMID:27901495 | Map3k13 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MAP3K13 mRNA | CTD | PMID:25181051 | Map3k13 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MAP3K13 mRNA | CTD | PMID:32145629 | Map3k13 | Rat | bisphenol A | increases expression | ISO | Map3k13 (Mus musculus) | 6480464 | bisphenol A results in increased expression of MAP3K13 mRNA | CTD | PMID:30245210 | Map3k13 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of MAP3K13 gene | CTD | PMID:28505145 | Map3k13 | Rat | bisphenol F | increases expression | ISO | Map3k13 (Mus musculus) | 6480464 | bisphenol F results in increased expression of MAP3K13 mRNA | CTD | PMID:38685157 | Map3k13 | Rat | cadmium dichloride | increases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of MAP3K13 mRNA | CTD | PMID:38174414|PMID:38568856 | Map3k13 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of MAP3K13 mRNA | CTD | PMID:36928142 | Map3k13 | Rat | chlorpyrifos | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of MAP3K13 mRNA | CTD | PMID:37019170 | Map3k13 | Rat | clofibrate | increases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Clofibrate results in increased expression of MAP3K13 mRNA | CTD | PMID:23811191 | Map3k13 | Rat | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of MAP3K13 mRNA | CTD | PMID:32741897 | Map3k13 | Rat | copper atom | multiple interactions | ISO | MAP3K13 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of MAP3K13 mRNA | CTD | PMID:24690739 | Map3k13 | Rat | copper(0) | multiple interactions | ISO | MAP3K13 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of MAP3K13 mRNA | CTD | PMID:24690739 | Map3k13 | Rat | copper(II) sulfate | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of MAP3K13 mRNA | CTD | PMID:19549813 | Map3k13 | Rat | cyclosporin A | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MAP3K13 mRNA | CTD | PMID:20106945|PMID:25562108 | Map3k13 | Rat | D-glucose | multiple interactions | ISO | Map3k13 (Mus musculus) | 6480464 | fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAP3K13 mRNA] | CTD | PMID:33448797 | Map3k13 | Rat | D-glucose | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Glucose results in decreased expression of MAP3K13 mRNA | CTD | PMID:33448797 | Map3k13 | Rat | D-glucose | increases methylation | ISO | Map3k13 (Mus musculus) | 6480464 | Glucose results in increased methylation of MAP3K13 gene | CTD | PMID:33448797 | Map3k13 | Rat | Dibutyl phosphate | affects expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of MAP3K13 mRNA | CTD | PMID:37042841 | Map3k13 | Rat | dicrotophos | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of MAP3K13 mRNA | CTD | PMID:28302478 | Map3k13 | Rat | disulfiram | multiple interactions | ISO | MAP3K13 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of MAP3K13 mRNA | CTD | PMID:24690739 | Map3k13 | Rat | diuron | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Diuron results in decreased expression of MAP3K13 mRNA | CTD | PMID:35967413 | Map3k13 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of MAP3K13 mRNA | CTD | PMID:29391264 | Map3k13 | Rat | ethanol | multiple interactions | ISO | MAP3K13 (Homo sapiens) | 6480464 | [Ethanol co-treated with Folic Acid] results in increased expression of MAP3K13 mRNA | CTD | PMID:23378141 | Map3k13 | Rat | fenofibrate | increases expression | EXP | | 6480464 | Fenofibrate results in increased expression of MAP3K13 mRNA | CTD | PMID:32741897 | Map3k13 | Rat | folic acid | multiple interactions | ISO | MAP3K13 (Homo sapiens) | 6480464 | [Ethanol co-treated with Folic Acid] results in increased expression of MAP3K13 mRNA | CTD | PMID:23378141 | Map3k13 | Rat | folic acid | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of MAP3K13 mRNA | CTD | PMID:25629700 | Map3k13 | Rat | fucoxanthin | multiple interactions | ISO | Map3k13 (Mus musculus) | 6480464 | fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAP3K13 mRNA] | CTD | PMID:33448797 | Map3k13 | Rat | glucose | increases methylation | ISO | Map3k13 (Mus musculus) | 6480464 | Glucose results in increased methylation of MAP3K13 gene | CTD | PMID:33448797 | Map3k13 | Rat | glucose | multiple interactions | ISO | Map3k13 (Mus musculus) | 6480464 | fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAP3K13 mRNA] | CTD | PMID:33448797 | Map3k13 | Rat | glucose | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Glucose results in decreased expression of MAP3K13 mRNA | CTD | PMID:33448797 | Map3k13 | Rat | glyphosate | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Glyphosate results in decreased expression of MAP3K13 mRNA | CTD | PMID:31295307 | Map3k13 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of MAP3K13 mRNA | CTD | PMID:30047161 | Map3k13 | Rat | methylmercury chloride | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of MAP3K13 mRNA | CTD | PMID:28001369 | Map3k13 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Map3k13 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAP3K13 mRNA | CTD | PMID:36189433 | Map3k13 | Rat | Nor-9-carboxy-delta9-THC | multiple interactions | ISO | MAP3K13 (Homo sapiens) | 6480464 | [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of MAP3K13 gene | CTD | PMID:30521419 | Map3k13 | Rat | paracetamol | affects expression | ISO | Map3k13 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MAP3K13 mRNA | CTD | PMID:17562736 | Map3k13 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MAP3K13 mRNA | CTD | PMID:33387578 | Map3k13 | Rat | paracetamol | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MAP3K13 mRNA | CTD | PMID:21420995 | Map3k13 | Rat | perfluorooctanoic acid | increases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of MAP3K13 mRNA | CTD | PMID:25868421 | Map3k13 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MAP3K13 mRNA | CTD | PMID:35163327 | Map3k13 | Rat | pirinixic acid | multiple interactions | ISO | Map3k13 (Mus musculus) | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of MAP3K13 mRNA | CTD | PMID:20813756 | Map3k13 | Rat | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of MAP3K13 mRNA | CTD | PMID:32741897 | Map3k13 | Rat | pirinixic acid | increases expression | ISO | Map3k13 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of MAP3K13 mRNA | CTD | PMID:18301758|PMID:20813756 | Map3k13 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of MAP3K13 mRNA | CTD | PMID:28903501 | Map3k13 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of MAP3K13 mRNA | CTD | PMID:30047161 | Map3k13 | Rat | quercetin | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of MAP3K13 mRNA | CTD | PMID:21632981 | Map3k13 | Rat | resorcinol | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | resorcinol results in decreased expression of MAP3K13 mRNA | CTD | PMID:22623647 | Map3k13 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of MAP3K13 mRNA | CTD | PMID:28374803 | Map3k13 | Rat | sertraline | increases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Sertraline results in increased expression of MAP3K13 mRNA | CTD | PMID:24865413 | Map3k13 | Rat | sodium arsenite | increases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MAP3K13 mRNA | CTD | PMID:22714537 | Map3k13 | Rat | sunitinib | increases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of MAP3K13 mRNA | CTD | PMID:31533062 | Map3k13 | Rat | tamoxifen | increases expression | ISO | Map3k13 (Mus musculus) | 6480464 | Tamoxifen results in increased expression of MAP3K13 mRNA | CTD | PMID:25123088 | Map3k13 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MAP3K13 mRNA] | CTD | PMID:31150632 | Map3k13 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of MAP3K13 mRNA | CTD | PMID:31150632 | Map3k13 | Rat | thapsigargin | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of MAP3K13 mRNA | CTD | PMID:22378314 | Map3k13 | Rat | trichostatin A | affects expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | trichostatin A affects the expression of MAP3K13 mRNA | CTD | PMID:28542535 | Map3k13 | Rat | triphenyl phosphate | affects expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of MAP3K13 mRNA | CTD | PMID:37042841 | Map3k13 | Rat | tunicamycin | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of MAP3K13 mRNA | CTD | PMID:22378314 | Map3k13 | Rat | valproic acid | increases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MAP3K13 mRNA | CTD | PMID:23179753 | Map3k13 | Rat | zinc sulfate | decreases expression | ISO | MAP3K13 (Homo sapiens) | 6480464 | Zinc Sulfate results in decreased expression of MAP3K13 mRNA | CTD | PMID:16330358 | | 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