Celsr1 (cadherin, EGF LAG seven-pass G-type receptor 1) - Rat Genome Database

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Gene: Celsr1 (cadherin, EGF LAG seven-pass G-type receptor 1) Rattus norvegicus
Analyze
Symbol: Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
RGD ID: 1560078
Description: Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Predicted to be involved in axonogenesis; cell-cell adhesion mediated by cadherin; and establishment of planar polarity. Predicted to act upstream of or within several processes, including apical protein localization; morphogenesis of an epithelium; and motor neuron migration. Predicted to be located in membrane and nucleoplasm. Predicted to be active in adherens junction and plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema and yellow nail syndrome. Orthologous to human CELSR1 (cadherin EGF LAG seven-pass G-type receptor 1); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cadherin EGF LAG seven-pass G-type receptor 1; cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila); flamingo-like protein celsr1; LOC300128
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87118,867,450 - 119,004,859 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7118,867,450 - 119,004,856 (-)EnsemblGRCr8
mRatBN7.27116,987,616 - 117,125,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7116,987,605 - 117,125,164 (-)EnsemblmRatBN7.2
Dahl_SR_JrHsd7120,903,514 - 121,040,909 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive7121,849,536 - 121,987,068 (-)NCBILyon_Normotensive
Lyon_Hypertensive7121,975,423 - 122,112,969 (-)NCBILyon_Hypertensive
F344_StmMcwi7120,467,481 - 120,604,871 (-)NCBIF344_StmMcwi
Rnor_6.07126,774,010 - 126,914,085 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7126,775,516 - 126,913,585 (-)Ensemblrn6Rnor6.0
Rnor_5.07126,484,850 - 126,625,684 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47123,900,366 - 124,036,122 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7113,278,640 - 113,416,057 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
clobetasol  (ISO)
cobalt dichloride  (EXP,ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (EXP,ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fucoxanthin  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glucose  (ISO)
inulin  (ISO)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
testosterone  (EXP)
tetrachloroethene  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
adherens junction  (IBA)
membrane  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Planar cell polarity signaling in vertebrates. Jones C and Chen P, Bioessays. 2007 Feb;29(2):120-32.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10932191   PMID:12842012   PMID:15632090   PMID:15744052   PMID:15955893   PMID:16687519   PMID:17229766   PMID:18849982   PMID:19357712   PMID:20223754   PMID:20353824   PMID:20631168  
PMID:20643356   PMID:20704721   PMID:32070035  


Genomics

Comparative Map Data
Celsr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87118,867,450 - 119,004,859 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7118,867,450 - 119,004,856 (-)EnsemblGRCr8
mRatBN7.27116,987,616 - 117,125,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7116,987,605 - 117,125,164 (-)EnsemblmRatBN7.2
Dahl_SR_JrHsd7120,903,514 - 121,040,909 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive7121,849,536 - 121,987,068 (-)NCBILyon_Normotensive
Lyon_Hypertensive7121,975,423 - 122,112,969 (-)NCBILyon_Hypertensive
F344_StmMcwi7120,467,481 - 120,604,871 (-)NCBIF344_StmMcwi
Rnor_6.07126,774,010 - 126,914,085 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7126,775,516 - 126,913,585 (-)Ensemblrn6Rnor6.0
Rnor_5.07126,484,850 - 126,625,684 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47123,900,366 - 124,036,122 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7113,278,640 - 113,416,057 (-)NCBICelera
Cytogenetic Map7q34NCBI
CELSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382246,361,174 - 46,537,620 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2246,360,834 - 46,537,620 (-)Ensemblhg38GRCh38
GRCh372246,757,071 - 46,933,517 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362245,135,395 - 45,311,731 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342245,077,249 - 45,253,586NCBI
Celera2230,664,148 - 30,840,512 (-)NCBICelera
Cytogenetic Map22q13.31NCBI
HuRef2229,700,771 - 29,879,343 (-)NCBIHuRef
CHM1_12246,715,504 - 46,891,675 (-)NCBICHM1_1
T2T-CHM13v2.02246,845,906 - 47,025,248 (-)NCBIT2T-CHM13v2.0
Celsr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391585,782,959 - 85,918,424 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1585,783,130 - 85,918,404 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381585,898,758 - 86,034,223 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1585,898,929 - 86,034,203 (-)Ensemblmm10GRCm38
GRCm38.p6 Ensembl1585,898,929 - 86,033,777 (-)Ensemblmm10GRCm38
MGSCv371585,729,188 - 85,864,207 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361585,726,695 - 85,861,543 (-)NCBIMGSCv36mm8
Celera1588,032,450 - 88,175,947 (-)NCBICelera
Cytogenetic Map15E2NCBI
cM Map1540.42NCBI
Celsr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541330,457,030 - 30,561,124 (-)Ensembl
ChiLan1.0NW_00495541330,455,194 - 30,561,124 (-)NCBIChiLan1.0ChiLan1.0
CELSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22356,187,757 - 56,373,480 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12258,881,830 - 59,067,171 (-)NCBINHGRI_mPanPan1
PanPan1.12245,427,275 - 45,604,286 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2245,428,159 - 45,604,453 (-)EnsemblpanPan2panpan1.1
CELSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11019,704,104 - 19,836,886 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1019,707,804 - 19,837,481 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1019,627,660 - 19,761,740 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01020,441,895 - 20,572,829 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1020,441,951 - 20,572,830 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11020,159,738 - 20,293,475 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01020,471,194 - 20,605,951 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01020,654,864 - 20,787,972 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Celsr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049453,453,384 - 3,570,250 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366293,455,887 - 3,568,566 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366293,453,384 - 3,570,250 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC102159820
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl52,980,351 - 3,203,381 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.153,114,410 - 3,203,378 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25586,808 - 596,547 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CELSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11928,842,332 - 29,030,672 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1928,844,644 - 29,030,216 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604596,500,977 - 96,687,142 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Celsr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247523,425,901 - 3,535,400 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247523,426,317 - 3,537,219 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Celsr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11255,246,197 - 255,332,429 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Celsr1
1031 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:48
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000036025
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7116269196132020414Rat
1582240Sffal1Serum free fatty acids level QTL 13.40.0021blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)7118556868125929417Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
RH131921  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27116,987,647 - 116,987,828 (+)MAPPERmRatBN7.2
Rnor_6.07126,774,042 - 126,774,222NCBIRnor6.0
Rnor_5.07126,484,882 - 126,485,062UniSTSRnor5.0
RGSC_v3.47123,899,318 - 123,899,498UniSTSRGSC3.4
Celera7113,278,672 - 113,278,852UniSTS
RH 3.4 Map7922.9UniSTS
Cytogenetic Map7q34UniSTS
RH132102  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27116,987,483 - 116,987,675 (+)MAPPERmRatBN7.2
Rnor_6.07126,773,878 - 126,774,069NCBIRnor6.0
Rnor_5.07126,484,718 - 126,484,909UniSTSRnor5.0
RGSC_v3.47123,899,154 - 123,899,345UniSTSRGSC3.4
Celera7113,278,508 - 113,278,699UniSTS
RH 3.4 Map7922.4UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 159 89 88 57 80 57 6 341 179 11 138 81 92 31 14 14

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006226188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC135400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC141997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY212290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000036025   ⟹   ENSRNOP00000029944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7118,867,450 - 119,004,856 (-)Ensembl
mRatBN7.2 Ensembl7116,987,605 - 117,125,164 (-)Ensembl
Rnor_6.0 Ensembl7126,775,516 - 126,913,585 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000158184   ⟹   ENSRNOP00000100482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7118,867,450 - 119,004,856 (-)Ensembl
RefSeq Acc Id: NM_001427591   ⟹   NP_001414520
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87118,867,450 - 119,004,856 (-)NCBI
Dahl_SR_JrHsd7120,903,514 - 121,040,909 (-)NCBI
Lyon_Normotensive7121,849,536 - 121,987,068 (-)NCBI
Lyon_Hypertensive7121,975,423 - 122,112,969 (-)NCBI
F344_StmMcwi7120,467,481 - 120,604,871 (-)NCBI
RefSeq Acc Id: XM_006242167   ⟹   XP_006242229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87118,867,451 - 119,004,859 (-)NCBI
mRatBN7.27116,987,616 - 117,125,034 (-)NCBI
Rnor_6.07126,774,010 - 126,914,084 (-)NCBI
Rnor_5.07126,484,850 - 126,625,684 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039080317   ⟹   XP_038936245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87118,867,451 - 119,004,859 (-)NCBI
mRatBN7.27116,987,616 - 117,125,035 (-)NCBI
RefSeq Acc Id: XM_063263331   ⟹   XP_063119401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87118,867,451 - 119,004,859 (-)NCBI
RefSeq Acc Id: XP_006242229   ⟸   XM_006242167
- Peptide Label: isoform X1
- UniProtKB: A6HTF9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029944   ⟸   ENSRNOT00000036025
RefSeq Acc Id: XP_038936245   ⟸   XM_039080317
- Peptide Label: isoform X2
- UniProtKB: A6HTF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414520   ⟸   NM_001427591
- UniProtKB: F1MAS4 (UniProtKB/TrEMBL),   A6HTF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119401   ⟸   XM_063263331
- Peptide Label: isoform X3
- UniProtKB: A6HTF9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100482   ⟸   ENSRNOT00000158184
Protein Domains
Cadherin   EGF-like   G-protein coupled receptors family 2 profile   GAIN-B   Laminin EGF-like   Laminin G

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560078 AgrOrtholog
BioCyc Gene G2FUF-32521 BioCyc
Ensembl Genes ENSRNOG00000021285 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036025 ENTREZGENE
  ENSRNOT00000036025.7 UniProtKB/TrEMBL
  ENSRNOT00000158184.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.220.50 UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin-like UniProtKB/TrEMBL
  Cadherin_CELSR1-3_9th UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  ConA-like_subgrp UniProtKB/TrEMBL
  EG-like_dom UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  GAIN_B UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  Growth_fac_rcpt_N_dom UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
NCBI Gene 300128 ENTREZGENE
PANTHER CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 1 UniProtKB/TrEMBL
  FAT ATYPICAL CADHERIN-RELATED UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  Cadherin UniProtKB/TrEMBL
  Cadherin_CELSR2_9th UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  GAIN UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
PhenoGen Celsr1 PhenoGen
PRINTS CADHERIN UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021285 RatGTEx
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HormR UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  SM00112 UniProtKB/TrEMBL
Superfamily-SCOP Cadherin UniProtKB/TrEMBL
  ConA_like_lec_gl UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
  Family A G protein-coupled receptor-like UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0ABK0LG69_RAT UniProtKB/TrEMBL
  A6HTF9 ENTREZGENE, UniProtKB/TrEMBL
  F1MAS4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-27 Celsr1  cadherin, EGF LAG seven-pass G-type receptor 1  Celsr1  cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Celsr1  cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)  Celsr1  cadherin EGF LAG seven-pass G-type receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Celsr1  cadherin EGF LAG seven-pass G-type receptor 1  LOC300128  flamingo-like protein celsr1  Symbol and Name updated 1299863 APPROVED
2006-02-09 LOC300128  flamingo-like protein celsr1      Symbol and Name status set to provisional 70820 PROVISIONAL