Or13c25 (olfactory receptor family 13 subfamily C member 25) - Rat Genome Database

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Gene: Or13c25 (olfactory receptor family 13 subfamily C member 25) Rattus norvegicus
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Symbol: Or13c25
Name: olfactory receptor family 13 subfamily C member 25
RGD ID: 1333398
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane and nucleoplasm. Predicted to be active in plasma membrane. Orthologous to human OR13C8 (olfactory receptor family 13 subfamily C member 8); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); atrazine (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 851; olfactory receptor gene Olr851; olfactory receptor Olr851; Olr851
RGD Orthologs
Human
Mouse
Dog
Squirrel
Pig
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8572,314,084 - 72,315,043 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl572,314,084 - 72,315,043 (-)EnsemblGRCr8
mRatBN7.2567,518,691 - 67,519,650 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl567,518,123 - 67,527,767 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx569,426,799 - 69,427,758 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0571,223,530 - 71,224,489 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0571,215,611 - 71,216,570 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0569,577,499 - 69,578,458 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl569,577,499 - 69,578,458 (-)Ensemblrn6Rnor6.0
Rnor_5.0961,656,423 - 61,657,382 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4570,326,088 - 70,327,047 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera566,431,634 - 66,432,593 (-)NCBICelera
RGSC_v3.1570,331,200 - 70,332,160 (-)NCBI
Cytogenetic Map5q23NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
nucleoplasm  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or13c25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8572,314,084 - 72,315,043 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl572,314,084 - 72,315,043 (-)EnsemblGRCr8
mRatBN7.2567,518,691 - 67,519,650 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl567,518,123 - 67,527,767 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx569,426,799 - 69,427,758 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0571,223,530 - 71,224,489 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0571,215,611 - 71,216,570 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0569,577,499 - 69,578,458 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl569,577,499 - 69,578,458 (-)Ensemblrn6Rnor6.0
Rnor_5.0961,656,423 - 61,657,382 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4570,326,088 - 70,327,047 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera566,431,634 - 66,432,593 (-)NCBICelera
RGSC_v3.1570,331,200 - 70,332,160 (-)NCBI
Cytogenetic Map5q23NCBI
OR13C8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389104,569,168 - 104,570,130 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9104,569,168 - 104,570,130 (+)Ensemblhg38GRCh38
GRCh379107,331,449 - 107,332,411 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369106,371,270 - 106,372,232 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349104,411,003 - 104,411,966NCBI
Celera977,837,068 - 77,838,030 (+)NCBICelera
Cytogenetic Map9q31.1NCBI
HuRef976,934,248 - 76,935,210 (+)NCBIHuRef
CHM1_19107,478,333 - 107,479,295 (+)NCBICHM1_1
T2T-CHM13v2.09116,743,955 - 116,744,917 (+)NCBIT2T-CHM13v2.0
Or13c25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39452,910,833 - 52,911,792 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl452,910,207 - 52,919,178 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38452,910,833 - 52,911,792 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl452,910,207 - 52,919,178 (-)Ensemblmm10GRCm38
MGSCv37452,923,705 - 52,924,664 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36452,931,933 - 52,932,892 (-)NCBIMGSCv36mm8
Celera452,885,535 - 52,886,494 (-)NCBICelera
Cytogenetic Map4B2NCBI
cM Map428.57NCBI
OR13C8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11160,531,372 - 60,532,331 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1160,531,372 - 60,532,331 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1158,995,426 - 58,996,385 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01161,666,363 - 61,668,197 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1161,666,363 - 61,667,322 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11160,188,154 - 60,189,112 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01160,202,476 - 60,203,435 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01160,897,745 - 60,898,704 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101963672
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947175,720,053 - 175,721,007 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367931,369,732 - 1,371,355 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367931,370,405 - 1,371,359 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100152489
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,919,766 - 245,920,728 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11245,919,564 - 245,920,915 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21275,332,869 - 275,333,831 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC116888588
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1196,696,007 - 96,696,966 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Or13c25
1 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:76
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000045776
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
nervous system
renal system
reproductive system
respiratory system
5 3 3 2 2 12 5 10 14 1

Sequence


Ensembl Acc Id: ENSRNOT00000082758   ⟹   ENSRNOP00000071629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl572,314,084 - 72,315,043 (-)Ensembl
mRatBN7.2 Ensembl567,518,123 - 67,527,767 (-)Ensembl
Rnor_6.0 Ensembl569,577,499 - 69,578,458 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115547   ⟹   ENSRNOP00000097061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl567,518,123 - 67,527,767 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120192   ⟹   ENSRNOP00000083896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl567,518,125 - 67,527,767 (-)Ensembl
RefSeq Acc Id: NM_001000400   ⟹   NP_001000400
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8572,314,084 - 72,315,043 (-)NCBI
mRatBN7.2567,518,691 - 67,519,650 (-)NCBI
Rnor_6.0569,577,499 - 69,578,458 (-)NCBI
Rnor_5.0961,656,423 - 61,657,382 (-)NCBI
RGSC_v3.4570,326,088 - 70,327,047 (-)RGD
Celera566,431,634 - 66,432,593 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000400 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91723 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071629
  ENSRNOP00000071629.1
RefSeq Acc Id: NP_001000400   ⟸   NM_001000400
- UniProtKB: D3ZQT5 (UniProtKB/TrEMBL),   A6KDN2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071629   ⟸   ENSRNOT00000082758
Ensembl Acc Id: ENSRNOP00000083896   ⟸   ENSRNOT00000120192
Ensembl Acc Id: ENSRNOP00000097061   ⟸   ENSRNOT00000115547
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQT5-F1-model_v2 AlphaFold D3ZQT5 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333398 AgrOrtholog
BioCyc Gene G2FUF-41289 BioCyc
Ensembl Genes ENSRNOG00000052071 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082758 ENTREZGENE
  ENSRNOT00000082758.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:298040 UniProtKB/TrEMBL
NCBI Gene 298040 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or13c25 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000052071 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6KDN2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQT5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or13c25  olfactory receptor family 13 subfamily C member 25  Olr851  olfactory receptor 851  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr851  olfactory receptor 851   Olr851_predicted  olfactory receptor 851 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr851_predicted  olfactory receptor 851 (predicted)      Symbol and Name status set to approved 70820 APPROVED