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Gene: Sccpdh (saccharopine dehydrogenase (putative)) Rattus norvegicus

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Symbol:

Sccpdh

Name:

saccharopine dehydrogenase (putative)

RGD ID:

1311440

Description:

Predicted to enable oxidoreductase activity. Predicted to be involved in glycolipid biosynthetic process. Predicted to be located in midbody. Predicted to be active in lipid droplet. Orthologous to human SCCPDH (saccharopine dehydrogenase (putative)); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC103689999; LOC305021; probable saccharopine dehydrogenase; RGD1311440; saccharopine dehydrogenase-like oxidoreductase; similar to RIKEN cDNA C330023F11

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SCCPDH (saccharopine dehydrogenase (putative))	RGD	RGD
Mus musculus (house mouse):	Sccpdh (saccharopine dehydrogenase (putative))	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Sccpdh (saccharopine dehydrogenase (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SCCPDH (saccharopine dehydrogenase (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SCCPDH (saccharopine dehydrogenase (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sccpdh (saccharopine dehydrogenase (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SCCPDH (saccharopine dehydrogenase (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SCCPDH (saccharopine dehydrogenase (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sccpdh (saccharopine dehydrogenase (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Sccpdh (saccharopine dehydrogenase (putative))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Sccpdh (saccharopine dehydrogenase (putative))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SCCPDH (saccharopine dehydrogenase (putative))	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sccpdhb (saccharopine dehydrogenase b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sccpdha.1 (saccharopine dehydrogenase a, tandem duplicate 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sccpdha.2 (saccharopine dehydrogenase a, tandem duplicate 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F22F7.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Sccpdh1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Sccpdh2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y50D4B.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y50D4B.2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ldp-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sccpdh	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	93,932,086 - 93,953,840 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	93,912,395 - 93,954,192 (+)	Ensembl				GRCr8
mRatBN7.2	13	91,400,120 - 91,421,875 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	91,400,190 - 91,422,222 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	93,905,325 - 93,927,079 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	95,305,490 - 95,327,244 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	92,480,155 - 92,501,909 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	97,941,720 - 97,963,474 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	97,941,757 - 97,963,824 (+)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	13	97,702,097 - 97,724,153 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	102,717,994 - 102,739,748 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	95,349,783 - 95,371,537 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	90,951,306 - 90,973,041 (+)	NCBI		Celera
RGSC_v3.1	13	95,538,718 - 95,560,472 (+)	NCBI
Cytogenetic Map	13	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

5-fluorouracil (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

arsane (ISO)

arsenic atom (ISO)

benzatropine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

Brodifacoum (EXP)

Butylbenzyl phthalate (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

chlordecone (ISO)

chloroquine (EXP)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

ethanol (ISO)

eugenol (EXP)

fenthion (ISO)

folic acid (ISO)

fulvestrant (ISO)

hydrogen sulfide (ISO)

hydroquinone O-beta-D-glucopyranoside (ISO)

ivermectin (ISO)

L-methionine (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (ISO)

nefazodone (EXP)

panobinostat (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tamibarotene (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glycolipid biosynthetic process (IBA)

Cellular Component

lipid droplet (IBA,IEA,ISO)

membrane (IEA)

midbody (IEA,ISO)

mitochondrion (ISO)

Molecular Function

oxidoreductase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:14741744	PMID:15166316	PMID:15489334	PMID:18614015	PMID:19946888	PMID:20833797	PMID:21630459	PMID:21700703	PMID:22871113	PMID:34800366

Genomics

Comparative Map Data

Sccpdh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	93,932,086 - 93,953,840 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	93,912,395 - 93,954,192 (+)	Ensembl				GRCr8
mRatBN7.2	13	91,400,120 - 91,421,875 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	91,400,190 - 91,422,222 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	93,905,325 - 93,927,079 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	95,305,490 - 95,327,244 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	92,480,155 - 92,501,909 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	97,941,720 - 97,963,474 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	97,941,757 - 97,963,824 (+)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	13	97,702,097 - 97,724,153 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	102,717,994 - 102,739,748 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	95,349,783 - 95,371,537 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	90,951,306 - 90,973,041 (+)	NCBI		Celera
RGSC_v3.1	13	95,538,718 - 95,560,472 (+)	NCBI
Cytogenetic Map	13	q26	NCBI

SCCPDH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	246,724,409 - 246,768,137 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	246,724,064 - 246,768,137 (+)	Ensembl			hg38	GRCh38
GRCh37	1	246,887,711 - 246,931,439 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	244,954,001 - 244,998,062 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	220,179,744 - 220,223,684 (+)	NCBI		Celera
Cytogenetic Map	1	q44	NCBI
HuRef	1	217,266,816 - 217,320,028 (+)	NCBI		HuRef
CHM1_1	1	248,159,687 - 248,203,735 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	246,150,883 - 246,194,527 (+)	NCBI		T2T-CHM13v2.0

Sccpdh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	179,495,796 - 179,514,754 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	179,495,775 - 179,514,754 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	179,667,749 - 179,687,189 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	179,668,210 - 179,687,189 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	181,598,362 - 181,617,315 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	181,504,906 - 181,523,859 (+)	NCBI		MGSCv36	mm8
Celera	1	186,740,196 - 186,750,794 (+)	NCBI		Celera
Cytogenetic Map	1	H4	NCBI
cM Map	1	83.62	NCBI

Sccpdh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	9,582,429 - 9,617,936 (+)	Ensembl
ChiLan1.0	NW_004955406	9,582,429 - 9,617,936 (+)	NCBI	ChiLan1.0	ChiLan1.0

SCCPDH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	2,351,023 - 2,397,044 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	2,571,477 - 2,614,657 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	222,351,645 - 222,394,804 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	227,819,720 - 227,862,568 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	227,819,720 - 227,862,048 (+)	Ensembl			panPan2	panpan1.1

SCCPDH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	37,449,528 - 37,488,047 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	37,449,738 - 37,487,682 (+)	NCBI			canFam3	CanFam3.1
CanFam3.1 Ensembl	7	37,449,738 - 37,487,682 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	36,931,071 - 36,968,669 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	37,281,229 - 37,320,776 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	37,281,171 - 37,324,416 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	37,121,407 - 37,159,227 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	37,128,990 - 37,166,575 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	37,398,495 - 37,436,108 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sccpdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	50,437,567 - 50,469,957 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	4,276,920 - 4,310,146 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	4,277,340 - 4,309,717 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SCCPDH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	15,205,648 - 15,264,489 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	10	15,205,644 - 15,264,416 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	17,524,007 - 17,572,010 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SCCPDH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	83,763,742 - 83,814,843 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	83,763,852 - 83,814,325 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	86,045,765 - 86,113,269 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sccpdh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624771	12,935,789 - 12,969,425 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624771	12,935,789 - 12,969,444 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Sccpdh
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	57,994,740 - 58,016,225 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Sccpdh
244 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	94
Count of miRNA genes:	65
Interacting mature miRNAs:	71
Transcripts:	ENSRNOT00000003791, ENSRNOT00000057787
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	83286150	109350286	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	72984506	99745408	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

D13Got83

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	91,398,646 - 91,398,815 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	97,940,247 - 97,940,415	NCBI	Rnor6.0
Rnor_6.0	13	97,700,587 - 97,700,755	NCBI	Rnor6.0
Rnor_5.0	13	102,949,498 - 102,949,666	UniSTS	Rnor5.0
Rnor_5.0	13	102,716,521 - 102,716,689	UniSTS	Rnor5.0
RGSC_v3.4	13	95,348,311 - 95,348,478	RGD	RGSC3.4
RGSC_v3.4	13	95,348,310 - 95,348,478	UniSTS	RGSC3.4
Celera	13	90,949,837 - 90,950,005	UniSTS
RGSC_v3.1	13	95,537,247 - 95,537,414	RGD
RH 3.4 Map	13	605.4	UniSTS
RH 3.4 Map	13	605.4	RGD
RH 2.0 Map	13	671.1	RGD
Cytogenetic Map	13	q26	UniSTS

D13Got73

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	91,398,651 - 91,398,907 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	97,940,252 - 97,940,507	NCBI	Rnor6.0
Rnor_6.0	13	97,700,592 - 97,700,847	NCBI	Rnor6.0
Rnor_5.0	13	102,949,503 - 102,949,758	UniSTS	Rnor5.0
Rnor_5.0	13	102,716,526 - 102,716,781	UniSTS	Rnor5.0
RGSC_v3.4	13	95,348,315 - 95,348,570	UniSTS	RGSC3.4
RGSC_v3.4	13	95,348,314 - 95,348,570	RGD	RGSC3.4
Celera	13	90,949,842 - 90,950,097	UniSTS
RGSC_v3.1	13	95,537,250 - 95,537,506	RGD
Cytogenetic Map	13	q26	UniSTS

RH128743

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	91,422,017 - 91,422,202 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	97,963,617 - 97,963,801	NCBI	Rnor6.0
Rnor_6.0	13	97,723,957 - 97,724,141	NCBI	Rnor6.0
Rnor_5.0	13	102,739,891 - 102,740,075	UniSTS	Rnor5.0
Rnor_5.0	13	102,972,868 - 102,973,052	UniSTS	Rnor5.0
RGSC_v3.4	13	95,371,680 - 95,371,864	UniSTS	RGSC3.4
Celera	13	90,973,184 - 90,973,368	UniSTS
Cytogenetic Map	13	q26	UniSTS

AA850814

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	91,421,938 - 91,422,131 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	97,963,538 - 97,963,730	NCBI	Rnor6.0
Rnor_6.0	13	97,723,878 - 97,724,070	NCBI	Rnor6.0
Rnor_5.0	13	102,972,789 - 102,972,981	UniSTS	Rnor5.0
Rnor_5.0	13	102,739,812 - 102,740,004	UniSTS	Rnor5.0
RGSC_v3.4	13	95,371,601 - 95,371,793	UniSTS	RGSC3.4
Celera	13	90,973,105 - 90,973,297	UniSTS
RH 3.4 Map	13	605.2	UniSTS
Cytogenetic Map	13	q26	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
22	5	60	180	105	100	71	79	71	12	354	176	11	153	82	99	29	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC115369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000003791 ⟹ ENSRNOP00000003791

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	93,931,793 - 93,954,189 (+)	Ensembl
mRatBN7.2 Ensembl	13	91,400,190 - 91,422,222 (+)	Ensembl
Rnor_6.0 Ensembl	13	97,941,757 - 97,963,824 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000057787 ⟹ ENSRNOP00000054601

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	93,931,793 - 93,954,189 (+)	Ensembl
mRatBN7.2 Ensembl	13	91,400,223 - 91,421,875 (+)	Ensembl
Rnor_6.0 Ensembl	13	97,702,097 - 97,724,153 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000129164 ⟹ ENSRNOP00000102220

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	93,912,395 - 93,954,192 (+)	Ensembl

RefSeq Acc Id:

NM_001013985 ⟹ NP_001014007

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	93,932,086 - 93,953,840 (+)	NCBI
mRatBN7.2	13	91,400,120 - 91,421,875 (+)	NCBI
Rnor_6.0	13	97,941,720 - 97,963,474 (+)	NCBI
Rnor_5.0	13	102,717,994 - 102,739,748 (+)	NCBI
RGSC_v3.4	13	95,349,783 - 95,371,537 (+)	RGD
Celera	13	90,951,306 - 90,973,041 (+)	RGD

Sequence:

show sequence

CGACAGCGGCCAAGACAGCGGCGGTTGCTGCGCCCGGTACTGGGGTCGCGGCCTGAGGCGCAGG
CGCGGTGGACTCAGCCCGCCCCGGGCTGCGGCTCGCAGTGGACTCGTCATGGCGACGGAGCAGA
GGCCTTTCCAGCTGGTGGTGTTCGGCGCCTCTGGCTTCACCGGCCAGTTCGTGACGGAGGAGGT
GGCCCGGGAGCAGATGGCCTCGGAGCAGAGCTCCCGCCTGCCCTGGGCCGTGGCGGGCCGCTCC
AAGGAGAAGCTGCAGCAAGTGCTGGAGAAGGCTGCCCAGAAGCTGGGAAGAGCAACACTATCAT
CTGAAGTTGGAATAATAATCTGTGATATCAGTAATCCAGCCTCACTTGATGAAATGGCTAAAAA
GGCAACACTTGTCCTCAACTGCGTAGGACCTTATCGATTTTATGGAGAACCTGTAGTAAAAGCA
TGTATTGAAAATGGAACAAGTTGCATTGACATCTGTGGGGAACCTCAGTTTCTGGAACTAATGC
ATGTAAAGTATCATGAGAAAGCTGCAGAGAAGGGGGTTTATATCATTGGAAGCAGTGGCTTTGA
CTCCATCCCAGCAGATCTAGGAGTGCTATACACCCGAAACCAGATGAACGGCACTTTAACTGCT
GTAGAAAGCTTTCTGACTATAAATTCGGGACCTGAGGGGTTGTGTATTCATGACGGAACCTGGA
AGTCAGCAATTTATGGTTTTGGCGATAAGGGCAGTTTAAGGAAACTGCGGAGTGTATCAAATCT
GAAACCTGTCCCAGTTATTGGCTCGAAGTTGAAAAGAAGGTGGCCAGTTAGCTATTGCAGAGAG
CTGAACTCGTATGCCATTCCTTTTTTGGGATCTGATATGTCGGTTGTGAAAAGGACTCAGCGTT
ACTTGCATGAAAATTTAGAGGACTCACCAGTTCAGTATGCCGCTTACATAACGGTGGGAGGCAT
CACCTCTGTGATTAAGCTGATGTTTGCAGGACTTTTCTTTTTATTCTTTGTGAAGTTTAGCATT
GGAAGACAACTTCTTGTAAAGTTCCCATGGCTCTTTTCCTTTGGTTATTTTTCAAAACGAGGTC
CAACACAAAAACAGATGGATGAGTCATCATTCACAATGACATTCTTTGGTCAAGGATACAGCCA
TGGCGTTAGTGCTGAAAAGAACAAACCAAATATCAGAATCTGTACTCAAGTGAAGGGACCAGAG
GCTGGCTACGTGGCTACTCCCATAGCCATGGTTCAGGCTGCCGTGACTTTCCTGAATGATGCCT
CTGACCTTCCAAAAGGGGGCGGTGTCTTCACTCCTGGAGCAGCCTTCTCCAGAACCAAGTTGAT
CGACAGACTCAACCAGCACGGCATTCAATTCAGTGTCATTAGCAGCTCTGAAGTGTAAACATTT
GAAGACTAATCTAATCATAAAATGCACAAATGCGTCTGTATTTGATATGTGAAATCCTTCATAT
GCTTGTCTGACTGTACGTGGACTCTCAAGTATAAAATATCTGTACATTAAAAGCAGGAAATTAT
ACTATCTTATCTAAACTCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001014007	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79215	(Get FASTA)	NCBI Sequence Viewer
	EDL94812	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000003791
	ENSRNOP00000003791.4
GenBank Protein	Q6AY30	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001014007 ⟸ NM_001013985

- UniProtKB:

Q6AY30 (UniProtKB/Swiss-Prot), A6JGF6 (UniProtKB/TrEMBL), A0A8L2QQT2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MATEQRPFQLVVFGASGFTGQFVTEEVAREQMASEQSSRLPWAVAGRSKEKLQQVLEKAAQKLG
RATLSSEVGIIICDISNPASLDEMAKKATLVLNCVGPYRFYGEPVVKACIENGTSCIDICGEPQ
FLELMHVKYHEKAAEKGVYIIGSSGFDSIPADLGVLYTRNQMNGTLTAVESFLTINSGPEGLCI
HDGTWKSAIYGFGDKGSLRKLRSVSNLKPVPVIGSKLKRRWPVSYCRELNSYAIPFLGSDMSVV
KRTQRYLHENLEDSPVQYAAYITVGGITSVIKLMFAGLFFLFFVKFSIGRQLLVKFPWLFSFGY
FSKRGPTQKQMDESSFTMTFFGQGYSHGVSAEKNKPNIRICTQVKGPEAGYVATPIAMVQAAVT
FLNDASDLPKGGGVFTPGAAFSRTKLIDRLNQHGIQFSVISSSEV

hide sequence

Ensembl Acc Id:

ENSRNOP00000003791 ⟸ ENSRNOT00000003791

Ensembl Acc Id:

ENSRNOP00000054601 ⟸ ENSRNOT00000057787

Ensembl Acc Id:

ENSRNOP00000102220 ⟸ ENSRNOT00000129164

Protein Domains

Saccharopine dehydrogenase NADP binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AY30-F1-model_v2	AlphaFold	Q6AY30	1-429	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699053

Promoter ID:

EPDNEW_R9578

Type:

initiation region

Name:

LOC103689999_1

Description:

saccharopine dehydrogenase-like oxidoreductase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	97,941,820 - 97,941,880	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311440	AgrOrtholog
BioCyc Gene	G2FUF-17137	BioCyc
Ensembl Genes	ENSRNOG00000037984	Ensembl
	ENSRNOG00000046051	Ensembl
	ENSRNOG00000066712	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000003791	ENTREZGENE
	ENSRNOT00000003791.7	UniProtKB/Swiss-Prot
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:6889267	IMAGE-MGC_LOAD
	IMAGE:7131885	IMAGE-MGC_LOAD
InterPro	NAD(P)-bd_dom_sf	UniProtKB/Swiss-Prot
	Saccharopine_DH-like_oxidrdct	UniProtKB/Swiss-Prot
	Sacchrp_dh_NADP	UniProtKB/Swiss-Prot
KEGG Report	rno:305021	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:73004	IMAGE-MGC_LOAD
	MGC:94278	IMAGE-MGC_LOAD
NCBI Gene	305021	ENTREZGENE
PANTHER	SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE	UniProtKB/Swiss-Prot
	UNCHARACTERIZED	UniProtKB/Swiss-Prot
Pfam	Sacchrp_dh_NADP	UniProtKB/Swiss-Prot
PhenoGen	Sccpdh	PhenoGen
RatGTEx	ENSRNOG00000037984	RatGTEx
	ENSRNOG00000046051	RatGTEx
	ENSRNOG00000066712	RatGTEx
Superfamily-SCOP	SSF51735	UniProtKB/Swiss-Prot
UniProt	A0A8L2QQT2	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LMG5_RAT	UniProtKB/TrEMBL
	A6JGF6	ENTREZGENE, UniProtKB/TrEMBL
	Q6AY30	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Sccpdh	saccharopine dehydrogenase (putative)	LOC103689999	saccharopine dehydrogenase-like oxidoreductase	Data merged from RGD:9250610	737654	PROVISIONAL
2014-08-25	LOC103689999	saccharopine dehydrogenase-like oxidoreductase			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-30	Sccpdh	saccharopine dehydrogenase (putative)	RGD1311440	similar to RIKEN cDNA C330023F11	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1311440	similar to RIKEN cDNA C330023F11	RGD1311440_predicted	similar to RIKEN cDNA C330023F11 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1311440_predicted	similar to RIKEN cDNA C330023F11 (predicted)	LOC305021_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC305021_predicted	similar to RIKEN cDNA C330023F11 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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