Sccpdh (saccharopine dehydrogenase (putative))

Gene: Sccpdh (saccharopine dehydrogenase (putative)) Ictidomys tridecemlineatus

Analyze

Symbol:

Sccpdh

Name:

saccharopine dehydrogenase (putative)

RGD ID:

12516447

Description:

INVOLVED IN glycolipid biosynthetic process (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 54 (ortholog); gastrointestinal stromal tumor (ortholog); parathyroid carcinoma (ortholog); FOUND IN lipid droplet (inferred); membrane (inferred); midbody (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

putative saccharopine dehydrogenase (putative); saccharopine dehydrogenase-like oxidoreductase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	50,437,567 - 50,469,957 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	4,276,920 - 4,310,146 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	4,277,340 - 4,309,717 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 54 (ISO)

gastrointestinal stromal tumor (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glycolipid biosynthetic process (IEA)

Cellular Component

lipid droplet (IEA)

membrane (IEA)

midbody (IEA)

mitochondrion (IEA)

plasma membrane (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Sccpdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	50,437,567 - 50,469,957 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	4,276,920 - 4,310,146 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	4,277,340 - 4,309,717 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SCCPDH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	246,724,409 - 246,768,137 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	246,724,409 - 246,768,137 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	246,887,711 - 246,931,439 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	244,954,001 - 244,998,062 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	220,179,744 - 220,223,684 (+)	NCBI		Celera
Cytogenetic Map	1	q44	NCBI
HuRef	1	217,266,816 - 217,320,028 (+)	NCBI		HuRef
CHM1_1	1	248,159,687 - 248,203,735 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	246,150,883 - 246,194,527 (+)	NCBI		T2T-CHM13v2.0

Sccpdh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	179,495,796 - 179,514,754 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	179,495,775 - 179,514,754 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	179,667,749 - 179,687,189 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	179,668,210 - 179,687,189 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	181,598,362 - 181,617,315 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	181,504,906 - 181,523,859 (+)	NCBI		MGSCv36	mm8
Celera	1	186,740,196 - 186,750,794 (+)	NCBI		Celera
Cytogenetic Map	1	H4	NCBI
cM Map	1	83.62	NCBI

Sccpdh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	93,932,086 - 93,953,840 (+)	NCBI		GRCr8
mRatBN7.2	13	91,400,120 - 91,421,875 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	91,400,190 - 91,422,222 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	93,905,325 - 93,927,079 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	95,305,490 - 95,327,244 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	92,480,155 - 92,501,909 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	97,941,720 - 97,963,474 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	97,941,757 - 97,963,824 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	13	97,702,097 - 97,724,153 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	102,717,994 - 102,739,748 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	95,349,783 - 95,371,537 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	95,538,718 - 95,560,472 (+)	NCBI
Celera	13	90,951,306 - 90,973,041 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

Sccpdh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	9,582,429 - 9,617,936 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	9,582,429 - 9,617,936 (+)	NCBI	ChiLan1.0	ChiLan1.0

SCCPDH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	2,351,023 - 2,397,044 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	2,571,477 - 2,614,657 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	222,351,645 - 222,394,804 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	227,819,720 - 227,862,568 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	227,819,720 - 227,862,048 (+)	Ensembl	panpan1.1		panPan2

SCCPDH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	37,449,528 - 37,488,047 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	37,449,738 - 37,487,682 (+)	NCBI	CanFam3.1		canFam3	CanFam3.1
CanFam3.1 Ensembl	7	37,449,738 - 37,487,682 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	36,931,071 - 36,968,669 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	37,281,229 - 37,320,776 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	37,281,171 - 37,324,416 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	37,121,407 - 37,159,227 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	37,128,990 - 37,166,575 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	37,398,495 - 37,436,108 (+)	NCBI		UU_Cfam_GSD_1.0

SCCPDH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	15,205,648 - 15,264,489 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	15,205,644 - 15,264,416 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	17,524,007 - 17,572,010 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SCCPDH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	83,763,742 - 83,814,843 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	83,763,852 - 83,814,325 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	86,045,765 - 86,113,269 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sccpdh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624771	12,935,789 - 12,969,425 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624771	12,935,789 - 12,969,444 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005326557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000007499 ⟹ ENSSTOP00000006702

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936526	4,276,920 - 4,310,146 (-)	Ensembl

RefSeq Acc Id:

XM_005326557 ⟹ XP_005326614

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	50,437,567 - 50,469,957 (+)	NCBI
SpeTri2.0	NW_004936526	4,277,340 - 4,309,717 (-)	NCBI

Sequence:

show sequence

GGCGGTTGCTGCGCCCGGTACTGGAGTCGTGGCTTGAGGCGCAGGCGCAGTGCATTCAGCCCAC
CCCGGGCCTCGGCTCGCTGTGGACTCGTCATGGCGACCGAGCAAAGGCCTTTCCAGCTGGTGGT
TTTCGGCGCCTCCGGCTTCACGGGCCAGTTCGTGACCGAGGAGGTAGCCCGGGAGCAGGGGGCC
CCGGATCGGAGCTCCCCCCTGCCGTGGGCGGTGGCGGGCCGTTCCCGGGAGAAGCTGCAGCGAG
TGCTGGAGAAGGCTGCACTGAAGCTGGGAAGACCGACACTGCCATCTGAAGTTGGAGTAATAAT
TTGTGATATCACTAACCCAGCCTCACTGGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAAT
TGTGTAGGACCTTATCGATTTTATGGAGAACCTGTAGTAAAAGCATGTGTTGAAAATGGAACTA
GCTGTATTGACATCTGTGGAGAACCTGAGTTTCTGGAACTAATGTATTTGAAGTATCATGAGAA
AGCTGCTGAAAAAGGTGTTTATATCATTGGAAGCAGTGGCTTTGACTCCATTCCAGCAGATCTG
GGAGTAATATATACCAGAAATCAAATGAACGGTACTTTGACTGCTGTGGAAAGTTTTCTTACTG
TACATTCAGGACCTGAGGGATTGTGTATTCATGATGGTACCTGGAAGTCAGCAATTTATGGTTT
TGGAGCTCGGAGTAATTTGAGAAAACTAAGAAGTGCATCAAATCTGAAACCTGTCCCACTTATT
GGTACAAAATTGAAAAAAAGGTGGCCTGTTTCTTATTGTAGAGAACTCAACACATATTCCATTC
CTTTCTTGGGATCTGATATGTCTGTTGTAAAGCGGACTCAACGTTACTTGTATGAAGTTTTAGA
AGAATCACCAGTTCAATATGCTGCTTATATAACTGTGGGAGGCATCACCTCTGTTATTAAGCTG
ATGTTTGCAGGACTTTTCTTTTTATTTTTTGTGAGGTTTGGCATTGGAAGGCATCTTCTCATAA
AATTCCCATGGCTCTTCTCCTTTGGTTATTTTTCCAAACAAGGTCCAACACAAAAACAGATGGA
TGGCTCATCATTTACATTGACATTCTTTGGTCAAGGATACAAACAAGGCCTTTCTACTGATAAG
CTCAAACCAAATATCAGAATTTGTACTCAGGTGAAAGGACCAGAGGCTGGCTATGTGACTACCC
CCATAGCCATGGTTCAGGCAGCCATGACTCTTCTAAACGATGTCTCTGATCTTCCTAAGGCGGG
CGGTGTCTTCACACCTGGGGCAGCTTTCTCCAAAACAAAATTGATCGACAGACTCGGACAACAT
GGTATTGAATTTAGTGTCATTAGCAGCTCTGAAGTCTAAACATTTGAAGAATTAGCTGAAGTCA
TAAAATGCATGATTAACAGCTTCTGTATTTGATATTTGAAATTCTTCTATAAACCTATCTGACT
GTATATGGAAAAGATTGTCAAATCTAAATACCTACACATTAAAGGCAGGAAATTGTACTAGCTT
ACTCTAACTTTCAAATCTCAGCTGATTTATGATTTTCTTGCTTGTGAGAGAAAACTAATATTTG
ACTAATTTTTTCATTGAAATGTTCTTGGTAAATTTTATGAATGTGCTGGCAGGTCAGATGGTGG
AGGAAGTGTCCTTGTCTGTGTTGCTAACTGCATTCTAGTGAGGATTGCTGGGGTTGGCTTTCAG
CCAGGGCAGTAACTGCTGCCTTGCTTGCCATGGTGTTGAATGGAATCTCACCCTCCAGTGAGTT
TCTCTGCATATTGTGTGAGCTTTTGCTAAATTAAACTGCACTTTTTTTCTATTTTAGCATAGTT
TTTCACCCATCTACATTGATTTTGGACTGTTTACCTAAGTTGAATAATAAAGGATTTTCAATTG
AA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005326614	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000006702.3
GenBank Protein	KAG3257969	(Get FASTA)	NCBI Sequence Viewer
	KAG3257970	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005326614 ⟸ XM_005326557

- UniProtKB:

I3M9V4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MATEQRPFQLVVFGASGFTGQFVTEEVAREQGAPDRSSPLPWAVAGRSREKLQRVLEKAALKLG
RPTLPSEVGVIICDITNPASLDEMAKQATVVLNCVGPYRFYGEPVVKACVENGTSCIDICGEPE
FLELMYLKYHEKAAEKGVYIIGSSGFDSIPADLGVIYTRNQMNGTLTAVESFLTVHSGPEGLCI
HDGTWKSAIYGFGARSNLRKLRSASNLKPVPLIGTKLKKRWPVSYCRELNTYSIPFLGSDMSVV
KRTQRYLYEVLEESPVQYAAYITVGGITSVIKLMFAGLFFLFFVRFGIGRHLLIKFPWLFSFGY
FSKQGPTQKQMDGSSFTLTFFGQGYKQGLSTDKLKPNIRICTQVKGPEAGYVTTPIAMVQAAMT
LLNDVSDLPKAGGVFTPGAAFSKTKLIDRLGQHGIEFSVISSSEV

hide sequence

RefSeq Acc Id:

ENSSTOP00000006702 ⟸ ENSSTOT00000007499

Protein Domains

Saccharopine dehydrogenase NADP binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000007502	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000007499.3	UniProtKB/TrEMBL
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	Sacchrp_dh_NADP	UniProtKB/TrEMBL
NCBI Gene	Sccpdh	ENTREZGENE
PANTHER	SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	Sacchrp_dh_NADP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51735	UniProtKB/TrEMBL
UniProt	I3M9V4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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