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Gene: Tdrkh (tudor and KH domain containing) Rattus norvegicus

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Symbol:

Tdrkh

Name:

tudor and KH domain containing

RGD ID:

1311196

Description:

Predicted to enable RNA binding activity. Predicted to be involved in several processes, including P granule organization; male meiotic nuclear division; and piRNA processing. Predicted to be located in mitochondrion; pi-body; and piP-body. Predicted to be active in P granule. Orthologous to human TDRKH (tudor and KH domain containing); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC310652; RGD1311196; similar to hypothetical protein; tudor and KH domain containing protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TDRKH (tudor and KH domain containing)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tdrkh (tudor and KH domain containing protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tdrkh (tudor and KH domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TDRKH (tudor and KH domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TDRKH (tudor and KH domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tdrkh (tudor and KH domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TDRKH (tudor and KH domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TDRKH (tudor and KH domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tdrkh (tudor and KH domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tdrkh (tudor and KH domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GINS4 (GINS complex subunit 4)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	TDRKH (tudor and KH domain containing)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tdrkh (tudor and KH domain containing protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tdrkh (tudor and KH domain containing)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tdrkh (tudor and KH domain containing)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	papi	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	papi	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tdrkh	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	184,736,255 - 184,760,534 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	184,737,591 - 184,762,052 (+)	Ensembl				GRCr8
mRatBN7.2	2	182,049,175 - 182,071,516 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	182,049,215 - 182,070,755 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	189,712,414 - 189,733,897 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	187,516,655 - 187,538,169 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	182,344,882 - 182,366,365 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	195,649,813 - 195,674,217 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	195,651,930 - 195,674,616 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	215,130,507 - 215,152,911 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	189,384,598 - 189,406,184 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	174,599,591 - 174,620,986 (+)	NCBI		Celera
RGSC_v3.1	2	189,334,719 - 189,351,762 (+)	NCBI
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

azoospermia (ISO)

spinal muscular atrophy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

Brodifacoum (EXP)

butanal (ISO)

Butylbenzyl phthalate (EXP)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

chlorpyrifos (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

folic acid (ISO)

fragrance (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

heptanal (ISO)

hexanal (ISO)

inulin (ISO)

ivermectin (ISO)

lead(0) (ISO)

methylmercury chloride (ISO)

nonanal (ISO)

octanal (ISO)

okadaic acid (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

parathion (ISO)

PCB138 (EXP)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

propanal (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

thapsigargin (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fertilization (ISO)

male meiotic nuclear division (ISO)

P granule organization (IBA)

piRNA processing (IBA,ISO)

spermatogenesis (IBA,ISO)

Cellular Component

cytoplasm (ISO)

mitochondrion (IEA,ISO)

P granule (IBA)

pi-body (ISO)

piP-body (ISO)

Molecular Function

nucleic acid binding (IEA)

protein binding (ISO)

RNA binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:18614015	PMID:19918066	PMID:23714778

Genomics

Comparative Map Data

Tdrkh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	184,736,255 - 184,760,534 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	184,737,591 - 184,762,052 (+)	Ensembl				GRCr8
mRatBN7.2	2	182,049,175 - 182,071,516 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	182,049,215 - 182,070,755 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	189,712,414 - 189,733,897 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	187,516,655 - 187,538,169 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	182,344,882 - 182,366,365 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	195,649,813 - 195,674,217 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	195,651,930 - 195,674,616 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	215,130,507 - 215,152,911 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	189,384,598 - 189,406,184 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	174,599,591 - 174,620,986 (+)	NCBI		Celera
RGSC_v3.1	2	189,334,719 - 189,351,762 (+)	NCBI
Cytogenetic Map	2	q34	NCBI

TDRKH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	151,766,486 - 151,790,534 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	151,769,799 - 151,791,416 (-)	Ensembl			hg38	GRCh38
GRCh37	1	151,744,044 - 151,763,010 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	150,010,664 - 150,029,634 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	148,557,115 - 148,576,071	NCBI
Celera	1	124,858,715 - 124,877,693 (-)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	123,120,939 - 123,139,873 (-)	NCBI		HuRef
CHM1_1	1	153,139,168 - 153,158,334 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	150,889,872 - 150,914,019 (-)	NCBI		T2T-CHM13v2.0

Tdrkh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	94,320,551 - 94,342,161 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	94,320,580 - 94,341,975 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	94,413,243 - 94,434,854 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	94,413,273 - 94,434,668 (+)	Ensembl			mm10	GRCm38
MGSCv37	3	94,217,240 - 94,235,421 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	94,498,722 - 94,518,054 (+)	NCBI		MGSCv36	mm8
Celera	3	95,858,144 - 95,876,325 (+)	NCBI		Celera
Cytogenetic Map	3	F2.1	NCBI
cM Map	3	40.62	NCBI

Tdrkh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955589	631,462 - 649,936 (+)	Ensembl
ChiLan1.0	NW_004955589	630,989 - 649,936 (+)	NCBI	ChiLan1.0	ChiLan1.0

TDRKH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	98,032,230 - 98,051,946 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	97,783,329 - 97,803,137 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	127,128,857 - 127,149,197 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	130,772,891 - 130,792,942 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	130,774,515 - 130,792,942 (-)	Ensembl			panPan2	panpan1.1

TDRKH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	60,794,937 - 60,807,852 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	60,795,813 - 60,805,449 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	60,236,314 - 60,248,221 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	61,811,520 - 61,823,418 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	61,811,508 - 61,825,743 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	60,638,277 - 60,650,172 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	60,724,607 - 60,736,336 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	61,453,522 - 61,465,433 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tdrkh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	22,937,417 - 22,951,740 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	1,967,639 - 1,982,134 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	1,968,001 - 1,982,073 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TDRKH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	97,415,914 - 97,438,691 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	97,415,891 - 97,438,262 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	106,438,836 - 106,461,263 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TDRKH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	11,895,882 - 11,916,981 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	11,896,380 - 11,916,031 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	11,455,327 - 11,489,647 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tdrkh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	19,444,049 - 19,463,788 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624772	19,447,092 - 19,463,796 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tdrkh
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	62,741,185 - 62,763,551 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tdrkh
81 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	54
Count of miRNA genes:	44
Interacting mature miRNAs:	54
Transcripts:	ENSRNOT00000028299
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	163997722	225110681	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	169358774	214358774	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	138595962	205135428	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	124537199	209621565	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
12879836	Kidm61	Kidney mass QTL 61		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	154723085	199723085	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	145807215	190807215	Rat
12879837	Am2	Aortic mass QTL 2		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	154723085	199723085	Rat
10043139	Iddm55	Insulin dependent diabetes mellitus QTL 55	3.1	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	150313808	195313808	Rat
12879838	Cm86	Cardiac mass QTL 86		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	154723085	199723085	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	205135267	Rat
12879839	Cm85	Cardiac mass QTL 85		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	154723085	199723085	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170652929	215652929	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	220931218	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	171994826	205135428	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	143565208	188565208	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
12879840	Bw179	Body weight QTL 179		0.005	body mass (VT:0001259)	body weight (CMO:0000012)	2	154723085	199723085	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	139067258	192287892	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	159440760	195313808	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	144882354	205135428	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
1357991	Ael2	Aortic elastin QTL 2	4.2	0.000071	aorta elastin amount (VT:0003905)	aortic elastin	2	169227906	214227906	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1578671	Bmd10	Bone mineral density QTL 10	5.4		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	175931416	220931416	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	182024327	227024327	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	159440760	228950743	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	184482291	229482291	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	143746578	205135428	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150096616	195096616	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	145306936	212705578	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	113746222	205135428	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	147287892	192287892	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	223841096	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	117415288	205135428	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150096616	195096616	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	182635347	227635347	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	220008837	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	165453811	210453811	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	163253030	208253030	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat

Markers in Region

D2Got353

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,053,950 - 182,054,089 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	195,656,666 - 195,656,804	NCBI	Rnor6.0
Rnor_5.0	2	215,135,360 - 215,135,498	UniSTS	Rnor5.0
RGSC_v3.4	2	189,389,307 - 189,389,445	UniSTS	RGSC3.4
Celera	2	174,604,327 - 174,604,454	UniSTS
Cytogenetic Map	2	q34	UniSTS

AW531502

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,048,154 - 182,048,317 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	195,650,870 - 195,651,032	NCBI	Rnor6.0
Rnor_5.0	2	215,129,564 - 215,129,726	UniSTS	Rnor5.0
RGSC_v3.4	2	189,383,511 - 189,383,673	UniSTS	RGSC3.4
Celera	2	174,598,531 - 174,598,693	UniSTS
RH 3.4 Map	2	1199.1	UniSTS
Cytogenetic Map	2	q34	UniSTS

AU046921

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	2	184,753,877 - 184,754,087 (+)	Marker Load Pipeline
mRatBN7.2	2	182,064,845 - 182,065,057 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	195,667,561 - 195,667,770	NCBI	Rnor6.0
Rnor_5.0	2	215,146,255 - 215,146,464	UniSTS	Rnor5.0
RGSC_v3.4	2	189,400,202 - 189,400,411	UniSTS	RGSC3.4
Cytogenetic Map	2	q34	UniSTS

RH136685

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,048,432 - 182,048,619 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	195,651,148 - 195,651,334	NCBI	Rnor6.0
Rnor_5.0	2	215,129,842 - 215,130,028	UniSTS	Rnor5.0
RGSC_v3.4	2	189,383,789 - 189,383,975	UniSTS	RGSC3.4
Celera	2	174,598,809 - 174,598,995	UniSTS
RH 3.4 Map	2	1197.58	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH137835

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,065,814 - 182,065,939 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	195,668,528 - 195,668,652	NCBI	Rnor6.0
Rnor_5.0	2	215,147,222 - 215,147,346	UniSTS	Rnor5.0
RGSC_v3.4	2	189,401,169 - 189,401,293	UniSTS	RGSC3.4
Celera	2	174,616,046 - 174,616,170	UniSTS
RH 3.4 Map	2	1198.1	UniSTS
Cytogenetic Map	2	q34	UniSTS

AI145009

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,071,121 - 182,071,302 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	195,673,835 - 195,674,015	NCBI	Rnor6.0
Rnor_5.0	2	215,152,529 - 215,152,709	UniSTS	Rnor5.0
RGSC_v3.4	2	189,406,476 - 189,406,656	UniSTS	RGSC3.4
Celera	2	174,621,353 - 174,621,533	UniSTS
RH 3.4 Map	2	1198.4	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	91	59	6	351	191	11	144	77	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC133978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC059161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000028299 ⟹ ENSRNOP00000028298

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	184,737,592 - 184,759,656 (+)	Ensembl
mRatBN7.2 Ensembl	2	182,049,215 - 182,070,755 (+)	Ensembl
Rnor_6.0 Ensembl	2	195,651,930 - 195,673,468 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081335 ⟹ ENSRNOP00000072448

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	195,665,454 - 195,674,616 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000130858 ⟹ ENSRNOP00000103700

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	184,738,265 - 184,762,052 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000150036 ⟹ ENSRNOP00000100860

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	184,737,591 - 184,755,165 (+)	Ensembl

RefSeq Acc Id:

NM_001014038 ⟹ NP_001014060

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	184,738,247 - 184,759,785 (+)	NCBI
mRatBN7.2	2	182,049,215 - 182,070,755 (+)	NCBI
Rnor_6.0	2	195,651,930 - 195,673,468 (+)	NCBI
Rnor_5.0	2	215,130,507 - 215,152,911 (+)	NCBI
Celera	2	174,599,591 - 174,620,986 (+)	NCBI

Sequence:

show sequence

GCTAGGCGGCTGCGCCGAGGGAGCGACGGGGCGGCGGCGGTGCGGGTGAGGTGCGAGGCGAAGC
GCGCAGCGTGCAACTCTGGAGGAGCGGATGTTAAGTCGGAGTACAGCAGAAAATGTCCACCGAA
CGAACTTCATGGACAAACCTGTCCACTATTCAGAAAATAGCCCTGGGCCTGGGAATTCCAGCAA
GTGCGACAGTTGCCTACATCCTGTATCGTCGATACAGGGAAAGTAGAGAAGAGAGATTGACATT
TGTTGGAGAAGATGACATTGAAATAGAGATGCGAGTTCCCCAAGAAGCTGTGAAGCTCATCATT
GGTCGACAAGGAGCCAATATTAAACAGCTGCGGAAGCAGACAGGTGCTCGGATTGATGTGGACA
CGGAGGATGTAGGCGATGAGCGGGTGCTGCTGATCAGTGGTTTTCCTGTTCAGGTGTGCAAGGC
CAAAGCAGCAATCCATCAAATCCTGACAGAGAACACCCCAGTGTTTGAGCAACTCTCTGTCCCC
CAGAGATCTGTGGGCAGAATCATAGGGAGAGGCGGTGAGACCATTCGTTCTATCTGTAAGGCTT
CTGGAGCCAAAATCACTTGCGACAAGGAATCAGAGGGAACATTACTACTCTCACGACTTATAAA
AATCTCAGGAACACAGAAGGAAGTGGCTGCAGCCAAGCATCTGATACTGGAGAAAGTTTCAGAA
GATGAGGAACTTCGGAAGAGAATTGCCCATTCTGCAGAAACCAGAGTCCCCCGAAAGCAGCCAA
TCAGCGTGAGAAGAGAGGAAGTGACAGAGCCTGGTGGAGCTGGAGAAGCAGCTTTATGGAAAAA
TACAAATTCTAGCATGGGACCAGCTGCACCCCTGGAAGTTCCTCTCCGCAAAGGAGGTGGTGAT
ATGGTTGTTGTAGGACCAAAAGAAGGTTCCTGGGAGAAACCTAATGATGACAGCTTTCAGAATT
CTGGTGCCCAGAGCAGTCCAGAGACGTCTATGTTTGAAATTCCCAGTCCTGACTTCAGTTTCCA
TGCTGATGAGTACCTAGAAGTCTACGTTTCTGCTTCTGAACACCCTAACCACTTCTGGATCCAG
ATCATTGGTTCCCGCAGCCTACAGTTGGATAAACTTGTCAGTGAGATGACCCAGCACTATGAGA
ATAGTCTGCCTGAAGACCTGACTGTGCATGTAGGAGACATTGTAGCAGCACCCTTATCTACAAA
TGGTTCCTGGTATCGAGCCCGGGTTCTGGGAACCTTGGAAAATGGAAACTTGGACCTCTACTTT
GTTGACTTTGGAGATAATGGAGATTGCCCACTAAAGGATCTCAGGGCTCTCAGGAGTGACTTTC
TAAGTCTCCCATTTCAAGCAATAGAATGCAGTCTGGCACGGATTGCCCCCTCAGGTGAAGAGTG
GGAAGAGGAAGCTCTAGATGAGTTTGACAGACTCACTCACTGTGCTGACTGGAAGCCCCTGGTG
GCCAAGATTTCTAGCTATGTCCAGACTGGAATTTCAACTTGGCCAAAGGTCTATTTATATGATA
CCAGCAATGGAAAGAAACTTGATATTGGGCTAGAATTAGTTCGTAAAGGATATGCAGTTGAACT
TCCTGAAGACATGGAAGAAAATAGAACTGTCCCAGATATGTTGAAGGACATGGCCACAGAAACA
GATGATTCTCTTGCAAGCATACTCACTGAGACAAAAAAGAGCCCTGAAGAGATACCACATACCC
TGTCCTGCCTCAGCTTATCAGAAGCTGCCTCTATGTCTGGTGATGATAACCTTGAAGATGACTT
ATTCTGAAATTTGGGCTTCAGCTGCTGGATCAGCCATCTGCTTTGCTGTGTGAGTGGTGCTGTC
ATCTGTCTGTAGCAACAGGAAAGTAGTGGGGGTGACAACACCCTCTTCCCTGTGCTCCTACGTG
TGTACATTTGTCTGCCGCATCTTTGATGCAGCTTAACCTGCTCTCAGTCC

hide sequence

RefSeq Acc Id:

XM_006232870 ⟹ XP_006232932

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	184,738,222 - 184,760,534 (+)	NCBI
mRatBN7.2	2	182,049,175 - 182,071,516 (+)	NCBI
Rnor_6.0	2	195,651,912 - 195,674,217 (+)	NCBI
Rnor_5.0	2	215,130,507 - 215,152,911 (+)	NCBI

Sequence:

show sequence

GCGGCTAAAAAGCGGTCCGCTAGGCGGCTGCGCCGAGGGAGCGACGGGGCGGCGGCGGTGCGGG
TGAGGTGCGAGGCGAAGCGCGCAGCGTGCAACTCTGGAGGAGCGGATGTTAAGTCGGAGTACAG
CAGAAAATGTCCACCGAACGAACTTCATGGACAAACCTGTCCACTATTCAGAAAATAGCCCTGG
GCCTGGGAATTCCAGCAAGTGCGACAGTTGCCTACATCCTGTATCGTCGATACAGGGAAAGTAG
AGAAGAGAGATTGACATTTGTTGGAGAAGATGACATTGAAATAGAGATGCGAGTTCCCCAAGAA
GCTGTGAAGCTCATCATTGGTCGACAAGGAGCCAATATTAAACAGCTGCGGAAGCAGACAGGTG
CTCGGATTGATGTGGACACGGAGGATGTAGGCGATGAGCGGGTGCTGCTGATCAGTGGTTTTCC
TGTTCAGGTGTGCAAGGCCAAAGCAGCAATCCATCAAATCCTGACAGAGAACACCCCAGTGTTT
GAGCAACTCTCTGTCCCCCAGAGATCTGTGGGCAGAATCATAGGGAGAGGCGGTGAGACCATTC
GTTCTATCTGTAAGGCTTCTGGAGCCAAAATCACTTGCGACAAGGAATCAGAGGGAACATTACT
ACTCTCACGACTTATAAAAATCTCAGGAACACAGAAGGAAGTGGCTGCAGCCAAGCATCTGATA
CTGGAGAAAGTTTCAGAAGATGAGGAACTTCGGAAGAGAATTGCCCATTCTGCAGAAACCAGAG
TCCCCCGAAAGCAGCCAATCAGCGTGAGAAGAGAGGAAGTGACAGAGCCTGGTGGAGCTGGAGA
AGCAGCTTTATGGAAAAATACAAATTCTAGCATGGGACCAGCTGCACCCCTGGAAGTTCCTCTC
CGCAAAGGAGGTGGTGATATGGTTGTTGTAGGACCAAAAGAAGGTTCCTGGGAGAAACCTAATG
ATGACAGCTTTCAGAATTCTGGTGCCCAGAGCAGTCCAGAGACGTCTATGTTTGAAATTCCCAG
TCCTGACTTCAGTTTCCATGCTGATGAGTACCTAGAAGTCTACGTTTCTGCTTCTGAACACCCT
AACCACTTCTGGATCCAGATCATTGGTTCCCGCAGCCTACAGTTGGATAAACTTGTCAGTGAGA
TGACCCAGCACTATGAGAATAGTCTGCCTGAAGACCTGACTGTGCATGTAGGAGACATTGTAGC
AGCACCCTTATCTACAAATGGTTCCTGGTATCGAGCCCGGGTTCTGGGAACCTTGGAAAATGGA
AACTTGGACCTCTACTTTGTTGACTTTGGAGATAATGGAGATTGCCCACTAAAGGATCTCAGGG
CTCTCAGGAGTGACTTTCTAAGTCTCCCATTTCAAGCAATAGAATGCAGTCTGGCACGGATTGC
CCCCTCAGGTGAAGAGTGGGAAGAGGAAGCTCTAGATGAGTTTGACAGACTCACTCACTGTGCT
GACTGGAAGCCCCTGGTGGCCAAGATTTCTAGCTATGTCCAGACTGGAATTTCAACTTGGCCAA
AGGTCTATTTATATGATACCAGCAATGGAAAGAAACTTGATATTGGGCTAGAATTAGTTCGTAA
AGGATATGCAGTTGAACTTCCTGAAGACATGGAAGAAAATAGAACTGTCCCAGATATGTTGAAG
GACATGGCCACAGAAACAGATGATTCTCTTGCAAGCATACTCACTGAGACAAAAAAGAGCCCTG
AAGAGATACCACATACCCTGTCCTGCCTCAGCTTATCAGAAGCTGCCTCTATGTCTGGTGATGA
TAACCTTGAAGATGACTTATTCTGAAATTTGGGCTTCAGCTGCTGGATCAGCCATCTGCTTTGC
TGTGGTGTGGTGCCAGGAGAGAGGAGTCTATGATAAGAGATCCATGAAGTCCTTTACTTCACAT
GTATGACTTGCTGTGGATCAGATCCATTTCCATTCCGTTGGACTTACCAGAAGGTGACAGAGAC
AAATGGAACCAGATTCCTCCACTTCACTCCTCTGGTCCCTCCCCTATCTTTCAATGCTGGAATG
CTGCTGCATAATTCCCAGCCTCTTCATGGCAGCTTCAGTTCCCTGCCAGTGATAATTTGCATTA
CTGCTAGGCTATGGTTTTTTTGTGGGGTTTTTTTGTATGTTTTGTTTGTTTTTTGAGGCTGGGA
AACAGCCAAGGTTTGGGCATTGGAAGTGAGGATTCTGCAGATTTCTGACTCACCTTATTAGTGA
CTATAGTTATAGGAAGTATTTGGTGGACTCAGAAGACTGCAGTTGTCAGGAGATAAGGCAAAAA
TCAGCATAAATATATTTAAAAGCTTCATGGGAGGGGAAGAGAGTGCTACCTCTCACCCTCAGTT
GCTGGGGCTGTTGGAGACAGGCGTGGTGAAGCAGTCCTCCAGCTGTTTCTTTGTGAACTTTAAA
GTACAACTAGAAAACGCAACCTAGGAAATGTTGTAAACTGCAAATATGTGTCTGTGTATACACA
CAACTAGAGAAAGAATGAATGTATAGTTCTGCTTAATTTGGGGAATTGTTTGCTAAATAAAGTT
CTCAAAAAAACTTA

hide sequence

RefSeq Acc Id:

XM_063281868 ⟹ XP_063137938

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	184,736,255 - 184,760,534 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014060	(Get FASTA)	NCBI Sequence Viewer
	XP_006232932	(Get FASTA)	NCBI Sequence Viewer
	XP_063137938	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH59161	(Get FASTA)	NCBI Sequence Viewer
	EDL85789	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000028298
	ENSRNOP00000028298.6
	ENSRNOP00000100860.1
	ENSRNOP00000103700
	ENSRNOP00000103700.1

RefSeq Acc Id:

NP_001014060 ⟸ NM_001014038

- UniProtKB:

G3V8T7 (UniProtKB/TrEMBL), A6K2Q7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSTERTSWTNLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAV
KLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVFEQ
LSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILE
KVSEDEELRKRIAHSAETRVPRKQPISVRREEVTEPGGAGEAALWKNTNSSMGPAAPLEVPLRK
GGGDMVVVGPKEGSWEKPNDDSFQNSGAQSSPETSMFEIPSPDFSFHADEYLEVYVSASEHPNH
FWIQIIGSRSLQLDKLVSEMTQHYENSLPEDLTVHVGDIVAAPLSTNGSWYRARVLGTLENGNL
DLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGEEWEEEALDEFDRLTHCADW
KPLVAKISSYVQTGISTWPKVYLYDTSNGKKLDIGLELVRKGYAVELPEDMEENRTVPDMLKDM
ATETDDSLASILTETKKSPEEIPHTLSCLSLSEAASMSGDDNLEDDLF

hide sequence

RefSeq Acc Id:	XP_006232932 ⟸ XM_006232870
- Peptide Label:	isoform X1
- UniProtKB:	G3V8T7 (UniProtKB/TrEMBL), A6K2Q7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSTERTSWTNLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAV KLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVFEQ LSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILE KVSEDEELRKRIAHSAETRVPRKQPISVRREEVTEPGGAGEAALWKNTNSSMGPAAPLEVPLRK GGGDMVVVGPKEGSWEKPNDDSFQNSGAQSSPETSMFEIPSPDFSFHADEYLEVYVSASEHPNH FWIQIIGSRSLQLDKLVSEMTQHYENSLPEDLTVHVGDIVAAPLSTNGSWYRARVLGTLENGNL DLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGEEWEEEALDEFDRLTHCADW KPLVAKISSYVQTGISTWPKVYLYDTSNGKKLDIGLELVRKGYAVELPEDMEENRTVPDMLKDM ATETDDSLASILTETKKSPEEIPHTLSCLSLSEAASMSGDDNLEDDLF hide sequence

Ensembl Acc Id:

ENSRNOP00000028298 ⟸ ENSRNOT00000028299

Ensembl Acc Id:

ENSRNOP00000072448 ⟸ ENSRNOT00000081335

RefSeq Acc Id:	XP_063137938 ⟸ XM_063281868
- Peptide Label:	isoform X1
- UniProtKB:	G3V8T7 (UniProtKB/TrEMBL), A6K2Q7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000103700 ⟸ ENSRNOT00000130858

Ensembl Acc Id:

ENSRNOP00000100860 ⟸ ENSRNOT00000150036

Protein Domains

K Homology Tudor

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V8T7-F1-model_v2	AlphaFold	G3V8T7	1-560	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691523

Promoter ID:

EPDNEW_R2047

Type:

multiple initiation site

Name:

Tdrkh_1

Description:

tudor and KH domain containing

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	195,651,929 - 195,651,989	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311196	AgrOrtholog
BioCyc Gene	G2FUF-52165	BioCyc
Ensembl Genes	ENSRNOG00000020860	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000028299	ENTREZGENE
	ENSRNOT00000028299.9	UniProtKB/TrEMBL
	ENSRNOT00000130858	ENTREZGENE
	ENSRNOT00000130858.1	UniProtKB/TrEMBL
	ENSRNOT00000150036.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.30.140	UniProtKB/TrEMBL
	2.40.50.90	UniProtKB/TrEMBL
	3.30.1370.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:6887770	IMAGE-MGC_LOAD
InterPro	IPR004087	UniProtKB/TrEMBL
	KH-I_TDRKH_rpt1	UniProtKB/TrEMBL
	KH-I_TDRKH_rpt2	UniProtKB/TrEMBL
	KH_dom_type_1_sf	UniProtKB/TrEMBL
	KH_type_1	UniProtKB/TrEMBL
	Staphylococcal_nuclease/TUDOR	UniProtKB/TrEMBL
	TDRD2-like_tudor	UniProtKB/TrEMBL
	Tudor	UniProtKB/TrEMBL
	Tudor_domain_containing	UniProtKB/TrEMBL
KEGG Report	rno:310652	UniProtKB/TrEMBL
MGC_CLONE	MGC:72982	IMAGE-MGC_LOAD
NCBI Gene	310652	ENTREZGENE
PANTHER	KH DOMAIN CONTAINING RNA BINDING PROTEIN	UniProtKB/TrEMBL
	TUDOR AND KH DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	TUDOR DOMAIN CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	KH_1	UniProtKB/TrEMBL
	TUDOR	UniProtKB/TrEMBL
PhenoGen	Tdrkh	PhenoGen
PROSITE	KH_TYPE_1	UniProtKB/TrEMBL
	TUDOR	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000020860	RatGTEx
SMART	SM00322	UniProtKB/TrEMBL
	TUDOR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54791	UniProtKB/TrEMBL
	Tudor/PWWP/MBT	UniProtKB/TrEMBL
UniProt	A0ABK0L3D0_RAT	UniProtKB/TrEMBL
	A0ABK0L8L7_RAT	UniProtKB/TrEMBL
	A6K2Q7	ENTREZGENE, UniProtKB/TrEMBL
	G3V8T7	ENTREZGENE, UniProtKB/TrEMBL
	Q6PCT7_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-23	Tdrkh	tudor and KH domain containing	Tdrkh	tudor and KH domain containing protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-27	Tdrkh	tudor and KH domain containing protein	RGD1311196	similar to hypothetical protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1311196	similar to hypothetical protein	RGD1311196_predicted	similar to hypothetical protein (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1311196_predicted	similar to hypothetical protein (predicted)	LOC310652_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC310652_predicted	similar to hypothetical protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar