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Gene: Plekhg4 (pleckstrin homology and RhoGEF domain containing G4) Rattus norvegicus

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Symbol:

Plekhg4

Name:

pleckstrin homology and RhoGEF domain containing G4

RGD ID:

1310790

Description:

Predicted to enable guanyl-nucleotide exchange factor activity. Orthologous to human PLEKHG4 (pleckstrin homology and RhoGEF domain containing G4); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rho/Rac/Cdc42 mediated signaling pathway; INTERACTS WITH alpha-Zearalanol; atrazine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC307796; pleckstrin homology domain containing, family G (with RhoGef domain) member 4; puratrophin-1; RGD1310790; similar to FLJ00068 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	50,161,722 - 50,176,491 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	50,159,754 - 50,182,133 (+)	Ensembl				GRCr8
mRatBN7.2	19	33,251,788 - 33,266,490 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	33,249,706 - 33,266,357 (+)	Ensembl				mRatBN7.2
Rnor_6.0	19	37,327,395 - 37,345,047 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	37,330,930 - 37,345,040 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	48,195,669 - 48,210,367 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	35,190,188 - 35,197,607 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	32,677,414 - 32,695,066 (+)	NCBI		Celera
RGSC_v3.1	19	35,190,890 - 35,202,169 (+)	NCBI
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

spinocerebellar ataxia 31 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-palmitoylglycerol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

alpha-Zearalanol (EXP)

amiodarone (ISO)

aristolochic acid A (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

coumarin (ISO)

D-glucose (ISO)

dexamethasone (ISO)

dimethylarsinic acid (ISO)

dorsomorphin (ISO)

entinostat (ISO)

folic acid (ISO)

gallic acid (ISO)

glucose (ISO)

GSK-J4 (ISO)

indometacin (ISO)

methylarsonic acid (ISO)

mono(2-ethylhexyl) phthalate (ISO)

Muconic dialdehyde (ISO)

niclosamide (ISO)

O-methyleugenol (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

quercetin (ISO)

rotenone (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Molecular Function

guanyl-nucleotide exchange factor activity (IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

insulin responsive facilitative sugar transporter mediated glucose transport pathway (ISO)

Rho/Rac/Cdc42 mediated signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation
6.	Rho GTPases in insulin-stimulated glucose uptake.	Satoh T Small GTPases. 2014;5:e28102. doi: 10.4161/sgtp.28102. Epub 2014 Mar 10.

Additional References at PubMed

PMID:23572525	PMID:25025572

Genomics

Comparative Map Data

Plekhg4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	50,161,722 - 50,176,491 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	50,159,754 - 50,182,133 (+)	Ensembl				GRCr8
mRatBN7.2	19	33,251,788 - 33,266,490 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	33,249,706 - 33,266,357 (+)	Ensembl				mRatBN7.2
Rnor_6.0	19	37,327,395 - 37,345,047 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	37,330,930 - 37,345,040 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	48,195,669 - 48,210,367 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	35,190,188 - 35,197,607 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	32,677,414 - 32,695,066 (+)	NCBI		Celera
RGSC_v3.1	19	35,190,890 - 35,202,169 (+)	NCBI
Cytogenetic Map	19	q12	NCBI

PLEKHG4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	67,277,580 - 67,289,480 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	67,277,510 - 67,289,499 (+)	Ensembl			hg38	GRCh38
GRCh37	16	67,312,065 - 67,323,383 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	65,868,914 - 65,880,884 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	16	51,819,638 - 51,831,669 (+)	NCBI		Celera
Cytogenetic Map	16	q22.1	NCBI
HuRef	16	53,184,495 - 53,196,466 (+)	NCBI		HuRef
CHM1_1	16	68,718,769 - 68,730,759 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	73,071,877 - 73,083,777 (+)	NCBI		T2T-CHM13v2.0

Plekhg4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	106,096,272 - 106,109,492 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	106,099,906 - 106,109,494 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	105,369,640 - 105,382,860 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	105,373,274 - 105,382,862 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	107,899,281 - 107,906,762 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	108,264,510 - 108,271,991 (+)	NCBI		MGSCv36	mm8
Celera	8	109,598,528 - 109,606,009 (+)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	53.04	NCBI

Plekhg4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955484	9,344,830 - 9,356,182 (-)	NCBI	ChiLan1.0	ChiLan1.0

PLEKHG4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	76,804,149 - 76,818,746 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	82,720,546 - 82,731,397 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	47,623,234 - 47,634,704 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	67,013,034 - 67,023,917 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	67,013,926 - 67,023,917 (+)	Ensembl			panPan2	panpan1.1

PLEKHG4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	82,075,536 - 82,102,846 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	82,075,852 - 82,102,168 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	82,082,780 - 82,092,426 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	82,528,434 - 82,538,080 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	82,510,764 - 82,537,406 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	82,354,537 - 82,364,183 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	82,040,113 - 82,049,760 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	82,679,358 - 82,689,004 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Plekhg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	41,829,897 - 41,856,261 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936475	17,737,734 - 17,746,109 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLEKHG4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	27,923,617 - 27,933,153 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	27,921,598 - 27,932,680 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	25,188,898 - 25,226,383 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLEKHG4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	60,157,217 - 60,177,105 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	60,163,553 - 60,174,765 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666047	22,910,275 - 22,930,175 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plekhg4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624746	19,037,195 - 19,046,741 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Plekhg4
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	17	25,099,139 - 25,108,082 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Plekhg4
47 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	115
Count of miRNA genes:	91
Interacting mature miRNAs:	97
Transcripts:	ENSRNOT00000022439
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	19220689	64220689	Rat
9590298	Uminl5	Urine mineral level QTL 5	3.59	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	19	7997750	52997750	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	46226778	74246245	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	36289	74246245	Rat
2313395	Anxrr26	Anxiety related response QTL 26			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	19	44385134	74246245	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	32539615	74246245	Rat
1558656	Prcs1	Prostate cancer susceptibility QTL 1	5		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	19	31287532	51431640	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	31777888	74246245	Rat
9590090	Insglur8	Insulin/glucose ratio QTL 8	10.81	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	19	7997750	52997750	Rat
1554318	Bmd5	Bone mineral density QTL 5	12.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	19	23188586	68188586	Rat
1549835	Tcas7	Tongue tumor susceptibility QTL 7		0.001	tongue integrity trait (VT:0010553)	squamous cell carcinoma of the head and neck tumor number (CMO:0001876)	19	41722546	74246245	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2194317	74246245	Rat
1354633	Bw28	Body weight QTL 28	6.04		body mass (VT:0001259)	body weight (CMO:0000012)	19	40727092	54856850	Rat
8552935	Pigfal10	Plasma insulin-like growth factor 1 level QTL 10	5.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	19	7997750	52997750	Rat
631840	Niddm38	Non-insulin dependent diabetes mellitus QTL 38	3.86		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	19	10329076	74246245	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	19	5748064	50748064	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	32365311	74246245	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	24093973	69093973	Rat
2303628	Vencon9	Ventilatory control QTL 9		0.005	respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	19	23188586	68188586	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10833618	74246245	Rat
9590250	Scort11	Serum corticosterone level QTL 11	23.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	7997750	52997750	Rat
1354607	Gmadr1	Adrenal mass QTL 1	5.83		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	19	40727092	54856850	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	20109306	65109306	Rat
1354600	Salc2	Saline consumption QTL 2	9.91	0.001	drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	19	40727092	54856850	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2194317	74246245	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	6	46	154	52	51	20	55	20	6	233	130	11	132	63	92	31	14	14

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001431313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774228	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022439 ⟹ ENSRNOP00000022439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	50,160,774 - 50,169,868 (+)	Ensembl
mRatBN7.2 Ensembl	19	33,250,853 - 33,259,433 (+)	Ensembl
Rnor_6.0 Ensembl	19	37,330,930 - 37,345,040 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099933 ⟹ ENSRNOP00000076499

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	50,161,773 - 50,182,133 (+)	Ensembl
mRatBN7.2 Ensembl	19	33,252,417 - 33,259,433 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104759 ⟹ ENSRNOP00000081851

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	50,159,754 - 50,169,868 (+)	Ensembl
mRatBN7.2 Ensembl	19	33,249,706 - 33,266,357 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111373 ⟹ ENSRNOP00000087289

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	50,162,139 - 50,176,517 (+)	Ensembl
mRatBN7.2 Ensembl	19	33,250,285 - 33,259,433 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000123433 ⟹ ENSRNOP00000102904

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	50,162,139 - 50,169,868 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000161025 ⟹ ENSRNOP00000105691

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	50,159,939 - 50,169,868 (+)	Ensembl

RefSeq Acc Id:

XM_006255483 ⟹ XP_006255545

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,162,064 - 50,176,491 (+)	NCBI
mRatBN7.2	19	33,251,789 - 33,266,490 (+)	NCBI
Rnor_6.0	19	37,328,701 - 37,345,047 (+)	NCBI
Rnor_5.0	19	48,195,669 - 48,210,367 (+)	NCBI

Sequence:

show sequence

GGGTGGCCTGGGACAAGAACCAAGGACAGAACCCAAGACTGGACCTGATGCTCACTGAAGCTAG
AGGAAGGAGGAATGACAGACTGGAGTTGGGGCTGGAGAAGGACAAGTCCAAGGCCATCCTAGAC
CCTTGCTTTTCTTCAGAATCTGCCGTAGAGTTGGAGATGGGTGGAGATGCCTGTTGCTTCTACT
ACAACTGCAGCTGATACCTAGATTCATGGAGGAAAGGCCTGCCTTAGAGCCAGGGAAGGAGAGG
AAGATGAGGTGCAAAGAGAAAAAGGTTCCTGGAGCACCCCATAACAGGTGAGTGGTGGAACTAG
GTCCCAGCTGGTCTCTGGCTCCAGGGCACCAGCTTTCTTAGCCACACTTTTCTGTGATTAGGGA
AAGAGAATTCAGGGCATCCAATGAGATGGAGGCTTTGAGCCTTACAAATTTCGTCAGGCTTGGG
TCAATTCCTACCCTGAGACATAGCTACCCTCTCCACCTTCCCGTTCAACAAGTTGTGGGATTTC
TCAATTTATTTCTTGTTTATTTCTTTGTCTTTTTGTTGTTTGTTTATTTGTTTTATTAATTAAA
CCTGGGGGCTCATACAAGTCAGGCAAGGGCTCTGCCACTGAGTTACACCTCACAGCCCATCCAA
TTTGTTTTGTGGTTGGGTGGCCTGGGAACCTGAAACAGAGAGTCAGGCTACAGAGAAGTGGTCC
TCACTGTGCGCGAAAATTATCCACAAGCAGCTGCCTGGGCTTAGGGAGTCTCTCTGGACACCGC
CCCTAATCATGGACTTGCATGTCTTTTGGGGGGCCAGATCTGGGGATCACGAGCGCTGAGTGGT
CCTCATCTTGTACAGGGAAGCTGGGCAAGTATTCTCTTGTCCCATTAAGGGGCTGGTGCGGAGC
CTTGCCCTCCTCCCACAAGGGCGTTCGTTGCTTTGTTCTTAAGCCTTCTTTCCATCTGGCAGTG
CTGCGGTTCACTCACCCTTTCAGACAGTTTCAACTCGGAGCAGATCAGGCAGTGAGCACAGTGG
AATGAGAGTTGCCGGGATCGGCAGAATGAGAAGTTGAGGGAGGGCCCGCCAAGTCTCCAAGGCG
CTGAGCATAGGAGACCACCCGCCCGCGGGCCGGGATGCACAGGGTAGGTGGCGGTAGGCGTTGT
CCCCAGCTCTCTTCTGCATCCTCCTGCTGTCAGAGCGGCGCCTTCCGGACGAGCCTGTGATTCG
GTCCTCCAGACCCTAGAGGGCGCCGCGTCCACAGCGGCCTTGCGGCCCTTCGAGCCACCAGAAG
GTGGCGCCCTTGGATTCTGGGCGGCCTCGCGGTATCCATCGTTGAGGCTGTGGTGCGTTTGTTC
TTCGTTAGTTCGAGGGCTCTGTAGTCTTCTGGCTTCAGAGTTCCCTACAGCGCGTCCCAGGGGT
GTGAGTGTGTGGGTGACCCGTGAGGGGCCGGGAGCACGGGTACAGGCACCTAGGGCAGGGCCTG
GCAGGTTGGGCTGGAGCGCAGAGCGGCGCGTGAGTCTGCTAAGCCTGGGGTGAAGGTGTGCCTG
AACATAGGGCCACCCCGTAGAGGCTCATGGAAGTGTAAGCCGGCCTTAGGCCCAAAGGAGACTC
TGTATCTTCAGTCACCAGACTGGACTACTTTAGCAGCCATGCGTCCGGGGACTCGGTACCCAGC
CTAGCACTTCCTACTGCCTAGTGTTCCCGGCTTACCTGCCCGCGGAGTCTTGCCCCACCATCTT
CAAACCAGTTCCTGGATAAGCTGAAGTCTCCTTTTACATCAAGGCCTAACCCGTTACCTATTTG
TCCAGAGCAAGCCCACTCTTACCAGGGAGTGATGGAAGGGCCTCTTGAGTGTGGGGATGTCTCC
CTAGACTACCAGGGCCATGCTGCAGATGGGAGGAGGTTTGTTGTGTGCAGTTTCAGGAACACCG
GGAAGGAGGAGGAACCTGCTCACCAGATACAGGCTATGGACCCAAGACTTTCAAGACCAGCAGT
AGGGGCAACCCAAGGCATAGGGCTACAAGGAGATTTCTTATCCAAGAAGCCTCAATCACTTCCA
GATCAAAGCGCTGCAGATAGGTCAGGGGGCAACCAGAGGAGCATATTAGGAGCCCCCCAAGCCC
AGTCAGAGGAGCCAGCCTTCTCTGAAATGGAAAACTGTTTGTGTCCTGGTTCCTCCCACCTCAA
CCTGACACAGGGTGAGAATGACCATCGAGGGGGAGGATTGATAGGGGACCCAGAGCCAGGCAGA
GCGCTGCCAGCTGGCTTTAGCCCTTTATTGGAGATGTCCTCAAAGCTACCGGAGGCAGACCCTA
GTGGATCCAGCTTCCCTAGGCCTGCTGACTGCCTCCTAGCTCGAGATCTCACCTGGGAGCTACT
GGCCAGCGGCATGGCTGCCCTCCCAGGGACACGGGACATAGAAGGCCGAGCAGTGCTACTTTTG
TGTGCCCACAGCCCAGCTTGGCTTCATCCCAAGTGTAATAGCCATGAGCTGCTGAGTCTTCTGT
TCTACCTACGAGGCATCCCCAGGCCTGAGGTGCAGGCTCTGGGACTGACCGTACTAGTGGATGC
CCGAATCTGCCCACCGAGCTCTGCCCTCACCTGGGGCCTCAGCCAACTACAAGAAGCATCCCCA
GGGTCTGTACAGCAACTGCTGCTGGTTGGGAAGATGCCCGAGGACATGCCCGTGGGGCTCCAGG
CCAAGCAGCTGGCTTCTCATCAGAGCCTCCTCACCCACATTCCTAACATGGAGTTGCCTACTTC
ACTAGGAGGATGCCTGTCTTACTGCCACCAAGCCTGGCTGGATTTCCGGATGCGTCTGGAAACC
CTACAGCAGAGTTGTCAGGTGGCTTGTGCCCTGCTTCAGGGCGTCATTGACAGTATGAAGGCTA
TGCGGCAGCCCTTGGAGTCTGGAGAAGTTGGTGAGCTGCTACAGCAGGCACAGTCCCTCATGCA
GCAGGTATTAGAGTCACCACAGTTGTCATGGTTACAAAGTCAGGGAAGCCTGGAGCTCGCATGG
TTGAAACAAGGGATGCCACAGGTGGCCCTGAGCCCCGATTACAGGTCTGCAGTAGACAAGGCTG
ATGAGTTGTATGGTCAAGTGGATGAACTGTTGCATCGGCTAACCCTGAAGAGCAACCAGCGAAT
CCGGGCCCTAGAGCTCCTCCAAGCACTGGAAGCCCAGGAGGGTGTGCTGTGCCAGATTGAAGTG
TGGCTACAGGAGGTGGGCTGGCCAGGGCTGGAGGAACCAGGGGAGCCCTCACTGGACATGCTAC
TCCAGGCCCAGGGCCCTTTTCAAGAGCTGGACCTGGTTGCCCAGGAACAGGTCAAGCAAGGGGA
GAAGTTACTGCAGCCATTAGTTGGCTGGGAGGCTGCTGAACTGGGGCCCACTGGAAAGCGCTTT
CTGGCCCTGAGATCCCAGCTGATGGAATTTTCCAGAGCTTTGGCCCAGCGGCGCCAGCGGTTGG
CAGATGCTGAGAAGCTGTTTCAGTTCTTTAAGCAGGCCTCAACATGGACGGAGGAAGGGCAGCG
GGTGCTGACAGAGCTGGAGCAGGAGACCCCGGAGGTTGTGCTGCAGCGACTGCAGCTGCACTGG
AGCAAACACCCTGACTTGCCTCCTGCCCACTTCCGGAAAATGTGGGCTCTGGCTACAGGCCTAG
GCTCAGAAGGCATTCGCCAGGAATGTCGCTGGGCCTGGGCACAGTGCCAGGACACCTGGCTGGC
TCTGGATCAGAAGCGTGAGGCTGCACTAAAGCCACAATCAATGAATAGCACAGCTACTTTGTAT
GTCAGGCGGGCTCCTGCTATACCCACCATCCCTCCACTGAGGAAGTCCTACAGCTTTGATCAGA
ATCTGGGGAAGCATCTTGGAGATGCTTCCAATCGTGGCCACTGTGCAGCCACTGTTACTGACTG
CCACAGACCTGAGGCCAGAGGAGGCATCCGGCCCAGGTCATCACCTTCTGTGCCTCTGTCAGGC
AGTTCTGACTTCAGGAGCCCCAACAGGCTACAGCTAGTATTGGCGGAGATGGTGGCCACAGAGC
GTGAGTATGTCCGGGCCCTTGACTACACCATACAGAACTACTTCCCTGAGTTAGATCGGTCCGA
TGTGCCCCAGGGCCTCCGTGGCCAGCGTGCACACCTCTTTGGCAACCTTGAAAAGCTTCGGGAT
TTCCACTTCCATTTCTTCCTGCGTGAGCTAGAGGCTTGCACCCGGCACCCACCTCGAGTGGCTC
ATGCCTTCCTGCGCCACAGGGTGCAGTTTGGAATGTATGCACTCTACAGCAAGAATAAACCTCG
GTCTGATGCCCTGATGAGCAACTATGGCCACACCTTCTTCAAGGAGAAGCAGCAGGCACTGGGA
GACCACCTGGACTTGGCTTCCTACCTGCTAAAGCCCATCCAGCGCATGAGCAAGTATGCCTTAC
TGCTGCAGGAGCTGGCGAGGGCCTGTGGGGGTCCAGCACAAGAGCTGGGTGCCCTTCAGGCAGC
CCAGAGCCTTGTGCATTTCCAGCTGAGACATGGCAATGACCTGCTAGCCATGGATGCCATTCAG
GGCTGTGACGTTAACCTCAAGGAGCAGGGGCAGTTGGTACGACAGGATGAGTTCACAGTGCGGG
CTGGGCACCACAAGTCCTGTCGTCGCGTTTTCCTGTTTGAGGAGCTGCTGCTCTTCAGCAAACC
TCGACGTGGGCCTGCAGGTGTTGACATATTCACCTACAAGCGTTCCTTCAAAATGGCAGACCTC
GGCCTCACGGAGTGCTGTGGGGAAAGTAAACTGCGCTTCGAGATCTGGTTCCGACGTCGCAAGG
CCAGGGACCTGTTTGTGCTTCAGGCTTCCGATGTGGCCACCAAACAAGCCTGGACAGCTGATAT
CTCCCGTCTCCTCTGGAGGCAGGCTGTACACAACAAGGAGGTGCGCATGGCTGAGATGGCATCC
ATGGGTGTGGGGAACAAAGCCTTCTGGGACATTGCCCCCAGTGAGGAGGCTATCAATGACCGCA
ACATCAACTATGTGCTGAAAAGACGAGATGTTCGCTCTAGGGCCTCCATTGCTGTGGCCCCATT
TGACTATGACAACCCTTATCTGGGTGCCTTGGCCTCCCTACCTGGAGACCGTGCCTCTTGCTCT
GTTCTGGGGTCTCTCAATCTGCACCTGTACAGAGATCCAGCTCTTCTGGGTGTTCACTGGTCCT
TGCTTCCACCCAACTTCCCAGAAGAAGCATCACTAGATACTGAGGTGGACTTGGGCAGCCAGCC
TTCTTTGACTCCTGAGGACTCAGAGGTCTCATCCCAGTGCCCATCAGCCAGTGGCTCTAGTGGT
TCTGACAGCAGCTGTGTGTCGGGGCAGACCATGGGCAGAGGCCTTGAAGACTTGTCCTGTGAAA
CAACAACCCTGGACTCAGGCCATCCCTGCTACTTCCAGGAGAGTGAGGAGATGGATGACTGTCT
TGGGTGAGGAGGGAAGTCCTCTGGAGTACTAATTTCAAAGGCACTGTTCTTTCTTTACTTGACC
CAGCTTTCTCAAGCCAGCTAGGTTGCTGCTCCTGTCCATCTAGATTGCCAGCTCCCTCTGGTCT
ATGAATGGTAATGTCCTAGGTGTGCAGTTTTTCATGCGCCCACTCAGAATGGAACTAGGAGTTT
CCCTTTTTGTACAGGATTAGACTGTGAACTCCAGAAGATAGGAATGAGCCCAAGTTGCTGACTC
ATTCTTTGAATGTCTATATGTGCCCTGGTACATGTAGTGCTCAATAAATGTGAAGTGTTGCTGA
ATGATAGTAATACAGTTGAAACTTTACATAAAACATGTCAATAAGA

hide sequence

RefSeq Acc Id:

XM_039098211 ⟹ XP_038954139

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,162,064 - 50,176,491 (+)	NCBI
mRatBN7.2	19	33,251,788 - 33,266,490 (+)	NCBI

RefSeq Acc Id:

XM_039098212 ⟹ XP_038954140

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,162,064 - 50,169,866 (+)	NCBI
mRatBN7.2	19	33,251,789 - 33,259,945 (+)	NCBI

RefSeq Acc Id:

XM_039098213 ⟹ XP_038954141

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,161,820 - 50,176,491 (+)	NCBI
mRatBN7.2	19	33,251,788 - 33,266,490 (+)	NCBI

RefSeq Acc Id:

XM_063278642 ⟹ XP_063134712

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,161,722 - 50,176,491 (+)	NCBI

RefSeq Acc Id:

XM_063278643 ⟹ XP_063134713

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,162,064 - 50,169,866 (+)	NCBI

RefSeq Acc Id:

XM_063278644 ⟹ XP_063134714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,161,722 - 50,176,491 (+)	NCBI

RefSeq Acc Id:

XM_063278645 ⟹ XP_063134715

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,161,722 - 50,169,866 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001418242	(Get FASTA)	NCBI Sequence Viewer
	NP_001418243	(Get FASTA)	NCBI Sequence Viewer
	XP_006255545	(Get FASTA)	NCBI Sequence Viewer
	XP_038954139	(Get FASTA)	NCBI Sequence Viewer
	XP_038954140	(Get FASTA)	NCBI Sequence Viewer
	XP_038954141	(Get FASTA)	NCBI Sequence Viewer
	XP_063134712	(Get FASTA)	NCBI Sequence Viewer
	XP_063134713	(Get FASTA)	NCBI Sequence Viewer
	XP_063134714	(Get FASTA)	NCBI Sequence Viewer
	XP_063134715	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL92374	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022439
	ENSRNOP00000022439.7
	ENSRNOP00000076499
	ENSRNOP00000076499.2
	ENSRNOP00000081851.2
	ENSRNOP00000087289
	ENSRNOP00000087289.2
	ENSRNOP00000102904
	ENSRNOP00000102904.1
	ENSRNOP00000105691.1

RefSeq Acc Id:	XP_006255545 ⟸ XM_006255483
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5Y027 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEGPLECGDVSLDYQGHAADGRRFVVCSFRNTGKEEEPAHQIQAMDPRLSRPAVGATQGIGLQG DFLSKKPQSLPDQSAADRSGGNQRSILGAPQAQSEEPAFSEMENCLCPGSSHLNLTQGENDHRG GGLIGDPEPGRALPAGFSPLLEMSSKLPEADPSGSSFPRPADCLLARDLTWELLASGMAALPGT RDIEGRAVLLLCAHSPAWLHPKCNSHELLSLLFYLRGIPRPEVQALGLTVLVDARICPPSSALT WGLSQLQEASPGSVQQLLLVGKMPEDMPVGLQAKQLASHQSLLTHIPNMELPTSLGGCLSYCHQ AWLDFRMRLETLQQSCQVACALLQGVIDSMKAMRQPLESGEVGELLQQAQSLMQQVLESPQLSW LQSQGSLELAWLKQGMPQVALSPDYRSAVDKADELYGQVDELLHRLTLKSNQRIRALELLQALE AQEGVLCQIEVWLQEVGWPGLEEPGEPSLDMLLQAQGPFQELDLVAQEQVKQGEKLLQPLVGWE AAELGPTGKRFLALRSQLMEFSRALAQRRQRLADAEKLFQFFKQASTWTEEGQRVLTELEQETP EVVLQRLQLHWSKHPDLPPAHFRKMWALATGLGSEGIRQECRWAWAQCQDTWLALDQKREAALK PQSMNSTATLYVRRAPAIPTIPPLRKSYSFDQNLGKHLGDASNRGHCAATVTDCHRPEARGGIR PRSSPSVPLSGSSDFRSPNRLQLVLAEMVATEREYVRALDYTIQNYFPELDRSDVPQGLRGQRA HLFGNLEKLRDFHFHFFLRELEACTRHPPRVAHAFLRHRVQFGMYALYSKNKPRSDALMSNYGH TFFKEKQQALGDHLDLASYLLKPIQRMSKYALLLQELARACGGPAQELGALQAAQSLVHFQLRH GNDLLAMDAIQGCDVNLKEQGQLVRQDEFTVRAGHHKSCRRVFLFEELLLFSKPRRGPAGVDIF TYKRSFKMADLGLTECCGESKLRFEIWFRRRKARDLFVLQASDVATKQAWTADISRLLWRQAVH NKEVRMAEMASMGVGNKAFWDIAPSEEAINDRNINYVLKRRDVRSRASIAVAPFDYDNPYLGAL ASLPGDRASCSVLGSLNLHLYRDPALLGVHWSLLPPNFPEEASLDTEVDLGSQPSLTPEDSEVS SQCPSASGSSGSDSSCVSGQTMGRGLEDLSCETTTLDSGHPCYFQESEEMDDCLG hide sequence

Ensembl Acc Id:

ENSRNOP00000022439 ⟸ ENSRNOT00000022439

RefSeq Acc Id:	XP_038954139 ⟸ XM_039098211
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5Y027 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038954141 ⟸ XM_039098213
- Peptide Label:	isoform X4
- UniProtKB:	D3ZQ60 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038954140 ⟸ XM_039098212
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5Y027 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000087289 ⟸ ENSRNOT00000111373

Ensembl Acc Id:

ENSRNOP00000076499 ⟸ ENSRNOT00000099933

Ensembl Acc Id:

ENSRNOP00000081851 ⟸ ENSRNOT00000104759

RefSeq Acc Id:	XP_063134712 ⟸ XM_063278642
- Peptide Label:	isoform X4
- UniProtKB:	D3ZQ60 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063134714 ⟸ XM_063278644
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063134715 ⟸ XM_063278645
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_063134713 ⟸ XM_063278643
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6AG98 (UniProtKB/TrEMBL), A0A8I5Y027 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000102904 ⟸ ENSRNOT00000123433

Ensembl Acc Id:

ENSRNOP00000105691 ⟸ ENSRNOT00000161025

Protein Domains

DH PH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZQ60-F1-model_v2	AlphaFold	D3ZQ60	1-1163	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310790	AgrOrtholog
BioCyc Gene	G2FUF-5833	BioCyc
Ensembl Genes	ENSRNOG00000016479	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000022439	ENTREZGENE
	ENSRNOT00000022439.8	UniProtKB/TrEMBL
	ENSRNOT00000099933	ENTREZGENE
	ENSRNOT00000099933.2	UniProtKB/TrEMBL
	ENSRNOT00000104759.2	UniProtKB/TrEMBL
	ENSRNOT00000111373	ENTREZGENE
	ENSRNOT00000111373.2	UniProtKB/TrEMBL
	ENSRNOT00000123433	ENTREZGENE
	ENSRNOT00000123433.1	UniProtKB/TrEMBL
	ENSRNOT00000161025.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.900.10	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
InterPro	DBL_dom_sf	UniProtKB/TrEMBL
	DH-domain	UniProtKB/TrEMBL
	PH_type	UniProtKB/TrEMBL
	Pleckstrin_homology	UniProtKB/TrEMBL
	Rho_GEF_signaling-related	UniProtKB/TrEMBL
	SOS1_NGEF_PH	UniProtKB/TrEMBL
NCBI Gene	307796	ENTREZGENE
PANTHER	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING, FAMILY G (WITH RHOGEF DOMAIN) MEMBER 4	UniProtKB/TrEMBL
	RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED	UniProtKB/TrEMBL
Pfam	RhoGEF	UniProtKB/TrEMBL
	SOS1_NGEF_PH	UniProtKB/TrEMBL
PhenoGen	Plekhg4	PhenoGen
PROSITE	DH_2	UniProtKB/TrEMBL
	PH_DOMAIN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000016479	RatGTEx
SMART	RhoGEF	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
Superfamily-SCOP	DH-domain	UniProtKB/TrEMBL
	PH domain-like	UniProtKB/TrEMBL
UniProt	A0A8I5Y027	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZTC9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AG98	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LL84_RAT	UniProtKB/TrEMBL
	A0ABK0LME9_RAT	UniProtKB/TrEMBL
	A6IYP6	ENTREZGENE, UniProtKB/TrEMBL
	D3ZQ60	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-30	Plekhg4	pleckstrin homology and RhoGEF domain containing G4	Plekhg4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Plekhg4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	Plekhg4_predicted	pleckstrin homology domain containing, family G (with RhoGef domain) member 4 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Plekhg4_predicted	pleckstrin homology domain containing, family G (with RhoGef domain) member 4 (predicted)	RGD1310790_predicted	similar to FLJ00068 protein (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1310790_predicted	similar to FLJ00068 protein (predicted)	LOC307796_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC307796_predicted	similar to FLJ00068 protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations