Mtss1 (MTSS I-BAR domain containing 1) - Rat Genome Database

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Gene: Mtss1 (MTSS I-BAR domain containing 1) Rattus norvegicus
Analyze
Symbol: Mtss1
Name: MTSS I-BAR domain containing 1
RGD ID: 1309883
Description: Predicted to enable several functions, including actin binding activity; identical protein binding activity; and phospholipid binding activity. Predicted to be involved in several processes, including adherens junction maintenance; positive regulation of actin filament bundle assembly; and renal tubule development. Predicted to act upstream of or within several processes, including actin filament polymerization; bone mineralization; and magnesium ion homeostasis. Predicted to be located in adherens junction and cytoplasm. Predicted to be active in actin cytoskeleton and cytoplasmic side of plasma membrane. Orthologous to human MTSS1 (MTSS I-BAR domain containing 1); PARTICIPATES IN Hedgehog signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362918; metastasis suppressor 1; metastasis suppressor protein 1; MTSS1, I-BAR domain containing
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8792,378,228 - 92,517,444 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl792,378,238 - 92,517,303 (-)EnsemblGRCr8
mRatBN7.2790,488,751 - 90,628,007 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl790,488,754 - 90,627,968 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx792,378,389 - 92,517,504 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0794,579,545 - 94,718,670 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0794,406,806 - 94,546,154 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0798,820,799 - 98,960,878 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl798,820,812 - 98,960,837 (-)Ensemblrn6Rnor6.0
Rnor_5.0799,419,324 - 99,558,069 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4795,808,266 - 95,947,927 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera787,254,103 - 87,391,446 (-)NCBICelera
RGSC_v3.1795,753,976 - 95,979,992 (+)NCBI
Cytogenetic Map7q33NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
asbestos  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (EXP)
bromobenzene  (EXP)
buspirone  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
dibenz[a,h]anthracene  (ISO)
diclofenac  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
FR900359  (ISO)
furan  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
isoprenaline  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
medroxyprogesterone acetate  (ISO)
mercury dibromide  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
nefazodone  (EXP)
nickel sulfate  (ISO)
nitrates  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (EXP)
phenformin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
succimer  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
tanespimycin  (ISO)
temozolomide  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12482861   PMID:12570871   PMID:14752106   PMID:17292833   PMID:20181743   PMID:21406566   PMID:23032931  


Genomics

Comparative Map Data
Mtss1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8792,378,228 - 92,517,444 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl792,378,238 - 92,517,303 (-)EnsemblGRCr8
mRatBN7.2790,488,751 - 90,628,007 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl790,488,754 - 90,627,968 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx792,378,389 - 92,517,504 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0794,579,545 - 94,718,670 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0794,406,806 - 94,546,154 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0798,820,799 - 98,960,878 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl798,820,812 - 98,960,837 (-)Ensemblrn6Rnor6.0
Rnor_5.0799,419,324 - 99,558,069 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4795,808,266 - 95,947,927 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera787,254,103 - 87,391,446 (-)NCBICelera
RGSC_v3.1795,753,976 - 95,979,992 (+)NCBI
Cytogenetic Map7q33NCBI
MTSS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388124,550,784 - 124,728,473 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8124,550,776 - 124,728,775 (-)Ensemblhg38GRCh38
GRCh378125,563,025 - 125,740,714 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368125,632,206 - 125,809,911 (-)NCBIBuild 36Build 36hg18NCBI36
Build 348125,632,211 - 125,809,840NCBI
Celera8121,751,140 - 121,928,858 (-)NCBICelera
Cytogenetic Map8q24.13NCBI
HuRef8120,888,491 - 121,064,564 (-)NCBIHuRef
CHM1_18125,603,268 - 125,780,983 (-)NCBICHM1_1
T2T-CHM13v2.08125,683,798 - 125,861,532 (-)NCBIT2T-CHM13v2.0
Mtss1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391558,813,083 - 58,955,805 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1558,813,083 - 58,953,854 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381558,941,234 - 59,083,956 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1558,941,234 - 59,082,005 (-)Ensemblmm10GRCm38
MGSCv371558,772,789 - 58,913,581 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361558,773,330 - 58,912,072 (-)NCBIMGSCv36mm8
Celera1560,471,026 - 60,611,759 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1525.09NCBI
Mtss1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555403,204,367 - 3,346,026 (-)Ensembl
ChiLan1.0NW_0049555403,204,357 - 3,346,026 (-)NCBIChiLan1.0ChiLan1.0
MTSS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27141,972,425 - 142,152,510 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18117,483,597 - 117,661,073 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08121,235,545 - 121,413,037 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18123,987,583 - 124,164,827 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8123,987,577 - 124,032,339 (-)EnsemblpanPan2panpan1.1
MTSS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11322,633,001 - 22,794,960 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1322,635,230 - 22,794,453 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1322,598,451 - 22,760,081 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01322,974,900 - 23,136,665 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1322,974,902 - 23,136,652 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11322,695,751 - 22,857,455 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01322,805,300 - 22,967,342 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01323,048,188 - 23,210,026 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mtss1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530315,537,415 - 15,690,947 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647022,963,496 - 23,117,226 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647022,963,498 - 23,117,923 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTSS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl414,933,331 - 15,103,253 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1414,933,290 - 15,103,256 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2415,692,248 - 15,759,809 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MTSS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18119,114,241 - 119,297,945 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8119,114,078 - 119,297,943 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603920,888,424 - 21,071,923 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtss1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473530,512,464 - 30,659,718 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473530,512,474 - 30,659,727 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mtss1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11233,467,346 - 233,606,645 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mtss1
566 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:310
Count of miRNA genes:200
Interacting mature miRNAs:253
Transcripts:ENSRNOT00000011984
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)771103011106126789Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
1641908Teswt1Testicular weight QTL 13.28testis mass (VT:1000644)both testes wet weight (CMO:0000175)78211124596700643Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
724537Niddm52Non-insulin dependent diabetes mellitus QTL 520.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)78211124595485241Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
RH129192  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2790,488,808 - 90,488,994 (+)MAPPERmRatBN7.2
Rnor_6.0798,820,857 - 98,821,042NCBIRnor6.0
Rnor_5.0799,419,382 - 99,419,567UniSTSRnor5.0
RGSC_v3.4795,947,688 - 95,947,873UniSTSRGSC3.4
Celera787,254,157 - 87,254,342UniSTS
Cytogenetic Map7q33UniSTS
RH133924  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2790,489,239 - 90,489,444 (+)MAPPERmRatBN7.2
Rnor_6.0798,821,288 - 98,821,492NCBIRnor6.0
Rnor_5.0799,419,813 - 99,420,017UniSTSRnor5.0
RGSC_v3.4795,947,238 - 95,947,442UniSTSRGSC3.4
Celera787,254,588 - 87,254,792UniSTS
RH 3.4 Map7612.9UniSTS
Cytogenetic Map7q33UniSTS
RH144190  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2790,532,824 - 90,533,025 (+)MAPPERmRatBN7.2
Rnor_6.0798,865,135 - 98,865,335NCBIRnor6.0
Rnor_5.0799,463,034 - 99,463,234UniSTSRnor5.0
RGSC_v3.4795,903,190 - 95,903,390UniSTSRGSC3.4
Celera787,297,493 - 87,297,693UniSTS
Cytogenetic Map7q33UniSTS
BF400005  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2790,622,534 - 90,622,754 (+)MAPPERmRatBN7.2
Rnor_6.0798,955,553 - 98,955,772NCBIRnor6.0
Rnor_5.0799,552,769 - 99,552,988UniSTSRnor5.0
RGSC_v3.4795,813,515 - 95,813,734UniSTSRGSC3.4
Celera787,386,607 - 87,386,826UniSTS
Cytogenetic Map7q33UniSTS
AW524128  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2790,490,324 - 90,490,414 (+)MAPPERmRatBN7.2
Rnor_6.0798,822,373 - 98,822,462NCBIRnor6.0
Rnor_5.0799,420,898 - 99,420,987UniSTSRnor5.0
RGSC_v3.4795,946,268 - 95,946,357UniSTSRGSC3.4
Celera787,255,673 - 87,255,762UniSTS
RH 3.4 Map7613.1UniSTS
Cytogenetic Map7q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001130563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011984   ⟹   ENSRNOP00000011984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl792,378,238 - 92,517,303 (-)Ensembl
mRatBN7.2 Ensembl790,488,764 - 90,627,842 (-)Ensembl
Rnor_6.0 Ensembl798,820,812 - 98,960,736 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080155   ⟹   ENSRNOP00000072200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl792,379,393 - 92,517,303 (-)Ensembl
mRatBN7.2 Ensembl790,490,846 - 90,627,968 (-)Ensembl
Rnor_6.0 Ensembl798,822,769 - 98,960,837 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095868   ⟹   ENSRNOP00000086949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl792,378,238 - 92,517,303 (-)Ensembl
mRatBN7.2 Ensembl790,488,754 - 90,627,968 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104332   ⟹   ENSRNOP00000097050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl792,378,238 - 92,517,303 (-)Ensembl
mRatBN7.2 Ensembl790,488,754 - 90,627,968 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118933   ⟹   ENSRNOP00000093281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl792,378,238 - 92,478,776 (-)Ensembl
mRatBN7.2 Ensembl790,488,754 - 90,627,968 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000138407   ⟹   ENSRNOP00000105357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl792,378,238 - 92,452,416 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000166506   ⟹   ENSRNOP00000102538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl792,378,238 - 92,517,303 (-)Ensembl
RefSeq Acc Id: NM_001130563   ⟹   NP_001124035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,229 - 92,517,303 (-)NCBI
mRatBN7.2790,488,755 - 90,627,842 (-)NCBI
Rnor_6.0798,820,803 - 98,960,736 (-)NCBI
Rnor_5.0799,419,324 - 99,558,069 (-)NCBI
RGSC_v3.4795,808,266 - 95,947,927 (+)RGD
Celera787,254,103 - 87,391,446 (-)RGD
Sequence:
RefSeq Acc Id: XM_017594954   ⟹   XP_017450443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,438 (-)NCBI
mRatBN7.2790,488,751 - 90,627,980 (-)NCBI
Rnor_6.0798,820,799 - 98,960,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594956   ⟹   XP_017450445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,442 (-)NCBI
mRatBN7.2790,488,751 - 90,627,988 (-)NCBI
Rnor_6.0798,820,799 - 98,960,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594957   ⟹   XP_017450446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,439 (-)NCBI
mRatBN7.2790,488,751 - 90,627,984 (-)NCBI
Rnor_6.0798,820,799 - 98,960,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079520   ⟹   XP_038935448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,438 (-)NCBI
mRatBN7.2790,488,751 - 90,627,984 (-)NCBI
RefSeq Acc Id: XM_039079525   ⟹   XP_038935453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,436 (-)NCBI
mRatBN7.2790,488,751 - 90,627,981 (-)NCBI
RefSeq Acc Id: XM_063263846   ⟹   XP_063119916
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,442 (-)NCBI
RefSeq Acc Id: XM_063263847   ⟹   XP_063119917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,439 (-)NCBI
RefSeq Acc Id: XM_063263848   ⟹   XP_063119918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,439 (-)NCBI
RefSeq Acc Id: XM_063263849   ⟹   XP_063119919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,443 (-)NCBI
RefSeq Acc Id: XM_063263850   ⟹   XP_063119920
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,404,243 (-)NCBI
RefSeq Acc Id: XM_063263851   ⟹   XP_063119921
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,404,239 (-)NCBI
RefSeq Acc Id: XM_063263852   ⟹   XP_063119922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,444 (-)NCBI
RefSeq Acc Id: XM_063263853   ⟹   XP_063119923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8792,378,228 - 92,517,440 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001124035 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426881 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426882 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426883 (Get FASTA)   NCBI Sequence Viewer  
  XP_017450443 (Get FASTA)   NCBI Sequence Viewer  
  XP_017450445 (Get FASTA)   NCBI Sequence Viewer  
  XP_017450446 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935448 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935453 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119916 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119917 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119918 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119919 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119920 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119921 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119922 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119923 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM16204 (Get FASTA)   NCBI Sequence Viewer  
  EDM16205 (Get FASTA)   NCBI Sequence Viewer  
  EDM16206 (Get FASTA)   NCBI Sequence Viewer  
  EDM16207 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011984.4
  ENSRNOP00000072200
  ENSRNOP00000072200.2
  ENSRNOP00000086949
  ENSRNOP00000086949.2
  ENSRNOP00000093281
  ENSRNOP00000093281.2
  ENSRNOP00000097050
  ENSRNOP00000097050.2
  ENSRNOP00000102538
  ENSRNOP00000102538.1
  ENSRNOP00000105357.1
RefSeq Acc Id: NP_001124035   ⟸   NM_001130563
- Sequence:
RefSeq Acc Id: XP_017450445   ⟸   XM_017594956
- Peptide Label: isoform X3
- UniProtKB: A6HRL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450443   ⟸   XM_017594954
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017450446   ⟸   XM_017594957
- Peptide Label: isoform X5
- Sequence:
Ensembl Acc Id: ENSRNOP00000072200   ⟸   ENSRNOT00000080155
Ensembl Acc Id: ENSRNOP00000011984   ⟸   ENSRNOT00000011984
RefSeq Acc Id: XP_038935448   ⟸   XM_039079520
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038935453   ⟸   XM_039079525
- Peptide Label: isoform X9
- UniProtKB: A0A8I6AN35 (UniProtKB/TrEMBL),   A6HRL7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086949   ⟸   ENSRNOT00000095868
Ensembl Acc Id: ENSRNOP00000093281   ⟸   ENSRNOT00000118933
Ensembl Acc Id: ENSRNOP00000097050   ⟸   ENSRNOT00000104332
RefSeq Acc Id: XP_063119922   ⟸   XM_063263852
- Peptide Label: isoform X12
- UniProtKB: A6HRL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119919   ⟸   XM_063263849
- Peptide Label: isoform X8
- UniProtKB: A6HRL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119916   ⟸   XM_063263846
- Peptide Label: isoform X4
- UniProtKB: A6HRL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119923   ⟸   XM_063263853
- Peptide Label: isoform X13
- UniProtKB: A6HRL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119918   ⟸   XM_063263848
- Peptide Label: isoform X7
- UniProtKB: A6HRL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119917   ⟸   XM_063263847
- Peptide Label: isoform X6
- UniProtKB: A0A0G2K2D5 (UniProtKB/TrEMBL),   A6HRL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119920   ⟸   XM_063263850
- Peptide Label: isoform X10
- UniProtKB: A6HRL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119921   ⟸   XM_063263851
- Peptide Label: isoform X11
- UniProtKB: A6HRL8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105357   ⟸   ENSRNOT00000138407
Ensembl Acc Id: ENSRNOP00000102538   ⟸   ENSRNOT00000166506
Protein Domains
IMD   WH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZYM5-F1-model_v2 AlphaFold D3ZYM5 1-790 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695354
Promoter ID:EPDNEW_R5879
Type:multiple initiation site
Name:Mtss1_1
Description:MTSS1, I-BAR domain containing
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0798,960,748 - 98,960,808EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309883 AgrOrtholog
BioCyc Gene G2FUF-33295 BioCyc
Ensembl Genes ENSRNOG00000009001 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011984.7 UniProtKB/TrEMBL
  ENSRNOT00000080155 ENTREZGENE
  ENSRNOT00000080155.3 UniProtKB/TrEMBL
  ENSRNOT00000095868 ENTREZGENE
  ENSRNOT00000095868.2 UniProtKB/TrEMBL
  ENSRNOT00000104332 ENTREZGENE
  ENSRNOT00000104332.2 UniProtKB/TrEMBL
  ENSRNOT00000118933 ENTREZGENE
  ENSRNOT00000118933.2 UniProtKB/TrEMBL
  ENSRNOT00000138407.1 UniProtKB/TrEMBL
  ENSRNOT00000166506 ENTREZGENE
  ENSRNOT00000166506.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
InterPro AH/BAR-dom UniProtKB/TrEMBL
  IRSp53/MIM_homology_IMD UniProtKB/TrEMBL
  MIM/ABBA UniProtKB/TrEMBL
  WH2_actin-bd UniProtKB/TrEMBL
KEGG Report rno:362918 UniProtKB/TrEMBL
NCBI Gene 362918 ENTREZGENE
PANTHER PTHR15708 UniProtKB/TrEMBL
  PTHR15708:SF10 UniProtKB/TrEMBL
Pfam IMD UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
PhenoGen Mtss1 PhenoGen
PROSITE IMD UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009001 RatGTEx
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
UniProt A0A0G2K2D5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFD6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN35 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AWT9 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LKU5_RAT UniProtKB/TrEMBL
  A0ABK0LT84_RAT UniProtKB/TrEMBL
  A6HRL5_RAT UniProtKB/TrEMBL
  A6HRL7 ENTREZGENE, UniProtKB/TrEMBL
  A6HRL8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZYM5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-04 Mtss1  MTSS I-BAR domain containing 1  Mtss1  MTSS1, I-BAR domain containing  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-09-21 Mtss1  MTSS1, I-BAR domain containing  Mtss1  metastasis suppressor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Mtss1  metastasis suppressor 1   Mtss1_predicted  metastasis suppressor 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mtss1_predicted  metastasis suppressor 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED