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Gene: Dmrta1 (DMRT-like family A1) Rattus norvegicus

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Symbol:

Dmrta1

Name:

DMRT-like family A1

RGD ID:

1309796

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to act upstream of or within male mating behavior and ovarian follicle development. Predicted to be active in nucleus. Orthologous to human DMRTA1 (DMRT like family A1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; aflatoxin B1.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

doublesex and mab-3 related transcription factor like family A1; doublesex- and mab-3-related transcription factor A1; LOC313352

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DMRTA1 (DMRT like family A1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Dmrta1 (doublesex and mab-3 related transcription factor like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dmrta1 (DMRT like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DMRTA1 (DMRT like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DMRTA1 (DMRT like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dmrta1 (DMRT like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DMRTA1 (DMRT like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DMRTA1 (DMRT like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dmrta1 (DMRT like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Dmrta1 (DMRT like family A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GAL3ST3 (galactose-3-O-sulfotransferase 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	DMRTA1 (DMRT like family A1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dmrta1 (doublesex and mab-3 related transcription factor like family A1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dmd-5	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	dmd-5	Alliance	DIOPT (OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	dmrt99B	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	dmrt99B	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	dmrta1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	109,531,704 - 109,538,244 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	109,531,586 - 109,538,246 (+)	Ensembl				GRCr8
mRatBN7.2	5	104,415,893 - 104,422,433 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	104,415,893 - 104,422,433 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	106,855,751 - 106,862,301 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	108,585,360 - 108,591,908 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	108,649,792 - 108,656,328 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	108,278,217 - 108,284,757 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	108,278,217 - 108,284,757 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	112,243,272 - 112,249,812 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	109,337,767 - 109,344,307 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	103,121,749 - 103,128,297 (+)	NCBI		Celera
RGSC_v3.1	5	109,104,948 - 109,347,367 (+)	NCBI
Cytogenetic Map	5	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

aflatoxin B1 (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

cisplatin (ISO)

cypermethrin (ISO)

dextran sulfate (ISO)

dibutyl phthalate (EXP,ISO)

N-nitrosodiethylamine (ISO)

paraquat (ISO)

phenobarbital (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triptonide (ISO)

XL147 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

male mating behavior (ISO)

ovarian follicle development (ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

sex differentiation (IBA)

Cellular Component

nucleus (IBA,IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

identical protein binding (IEA,ISO)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (IEA,ISO)

sequence-specific double-stranded DNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16982677	PMID:17605809	PMID:23679989

Genomics

Comparative Map Data

Dmrta1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	109,531,704 - 109,538,244 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	109,531,586 - 109,538,246 (+)	Ensembl				GRCr8
mRatBN7.2	5	104,415,893 - 104,422,433 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	104,415,893 - 104,422,433 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	106,855,751 - 106,862,301 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	108,585,360 - 108,591,908 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	108,649,792 - 108,656,328 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	108,278,217 - 108,284,757 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	108,278,217 - 108,284,757 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	112,243,272 - 112,249,812 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	109,337,767 - 109,344,307 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	103,121,749 - 103,128,297 (+)	NCBI		Celera
RGSC_v3.1	5	109,104,948 - 109,347,367 (+)	NCBI
Cytogenetic Map	5	q32	NCBI

DMRTA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	22,446,824 - 22,455,740 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	22,446,824 - 22,455,740 (+)	Ensembl			hg38	GRCh38
GRCh37	9	22,446,823 - 22,455,739 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	22,436,840 - 22,442,472 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	22,436,839 - 22,442,472	NCBI
Celera	9	22,385,141 - 22,390,773 (+)	NCBI		Celera
Cytogenetic Map	9	p21.3	NCBI
HuRef	9	22,410,720 - 22,416,354 (+)	NCBI		HuRef
CHM1_1	9	22,446,555 - 22,452,185 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	22,461,237 - 22,470,151 (+)	NCBI		T2T-CHM13v2.0

Dmrta1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	89,576,435 - 89,583,003 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	89,567,673 - 89,583,009 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	89,688,198 - 89,694,766 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	89,679,436 - 89,694,772 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	89,354,889 - 89,361,457 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	89,180,216 - 89,186,784 (+)	NCBI		MGSCv36	mm8
Celera	4	88,147,830 - 88,154,392 (+)	NCBI		Celera
Cytogenetic Map	4	C4	NCBI
cM Map	4	42.15	NCBI

Dmrta1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	11,920,468 - 11,927,988 (-)	Ensembl
ChiLan1.0	NW_004955472	11,923,796 - 11,925,127 (-)	NCBI	ChiLan1.0	ChiLan1.0

DMRTA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	102,107,167 - 102,112,823 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	102,109,835 - 102,118,768 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	22,280,250 - 22,289,180 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	22,895,686 - 22,901,290 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	22,895,891 - 22,900,745 (+)	Ensembl			panPan2	panpan1.1

DMRTA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	41,566,159 - 41,571,649 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	41,566,174 - 41,571,166 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	40,244,756 - 40,250,250 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	42,505,472 - 42,510,935 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	42,505,472 - 42,510,687 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	41,178,729 - 41,184,192 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	41,066,582 - 41,072,081 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	41,680,502 - 41,685,988 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dmrta1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	156,239,707 - 156,245,340 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936652	3,908,542 - 3,915,388 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936652	3,909,238 - 3,915,415 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DMRTA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	200,406,764 - 200,414,334 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	200,410,020 - 200,414,904 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	223,542,194 - 223,549,436 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DMRTA1
(Chlorocebus sabaeus - green monkey)

No map positions available.

Dmrta1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	26,309,744 - 26,318,326 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624736	26,309,929 - 26,318,249 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Dmrta1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	64,600,641 - 64,607,177 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Dmrta1
43 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	790
Count of miRNA genes:	302
Interacting mature miRNAs:	391
Transcripts:	ENSRNOT00000038972
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	102105698	152749382	Rat
1357396	Bw44	Body weight QTL 44	4.19		body mass (VT:0001259)	body weight (CMO:0000012)	5	73779642	118779642	Rat
2303586	Gluco52	Glucose level QTL 52	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	100826632	145826632	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
1298070	Scl18	Serum cholesterol level QTL 18	3.7		blood LDL cholesterol amount (VT:0000181)	calculated plasma low density lipoprotein cholesterol level (CMO:0001245)	5	84630798	129630798	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
2302381	Bw84	Body weight QTL 84	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
1357402	Bw46	Body weight QTL 46	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
7411582	Foco3	Food consumption QTL 3	7.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
1598859	Cm66	Cardiac mass QTL 66	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	84630798	129630798	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1582212	Livw2	Liver weight QTL 2	3.5	0.0004	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	5	104018576	124314782	Rat
7411564	Bw135	Body weight QTL 135		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	92583776	137583776	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	98972960	143972960	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
7411601	Foco12	Food consumption QTL 12	19.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
2303618	Vencon1	Ventilatory control QTL 1	3.8		respiration trait (VT:0001943)	oxygen consumption (CMO:0002169)	5	100826632	145826632	Rat
7394708	Emca11	Estrogen-induced mammary cancer QTL 11			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	73176602	118176602	Rat
1598846	Bp293	Blood pressure QTL 293	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	84630798	129630798	Rat
7394710	Emca12	Estrogen-induced mammary cancer QTL 12			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	94034903	139034903	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	69474415	114474415	Rat
1358909	Kidm25	Kidney mass QTL 25	1.87		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	95062526	133270832	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
1600362	Mcs19	Mammary carcinoma susceptibility QTL 19	2.5		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	82032155	127032155	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	74335621	156302135	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	64589016	109589016	Rat
1298086	Bp156	Blood pressure QTL 156			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	89369373	134369373	Rat
2290005	Mcs24	Mammary carcinoma susceptibility QTL 24			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	69835120	114835120	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	70969494	136328156	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	97492524	133270832	Rat
2312671	Scl64	Serum cholesterol level QTL 64		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	73779642	118779642	Rat
1358889	Bp261	Blood pressure QTL 261	2.86		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	95062526	133270832	Rat
6903316	Bw113	Body weight QTL 113	2	0.0103	body mass (VT:0001259)	body weight (CMO:0000012)	5	92881678	137881678	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	104262817	153890625	Rat

Markers in Region

D5Mit5

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	104,250,862 - 104,251,008 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	108,092,659 - 108,092,802	NCBI	Rnor6.0
Rnor_5.0	5	112,057,862 - 112,058,005	UniSTS	Rnor5.0
RGSC_v3.4	5	109,163,281 - 109,163,425	RGD	RGSC3.4
RGSC_v3.4	5	109,163,282 - 109,163,425	UniSTS	RGSC3.4
Celera	5	102,964,236 - 102,964,379	UniSTS
RGSC_v3.1	5	109,168,508 - 109,168,651	RGD
RH 3.4 Map	5	744.8	UniSTS
RH 3.4 Map	5	744.8	RGD
RH 2.0 Map	5	676.5	RGD
SHRSP x BN Map	5	58.1599	RGD
FHH x ACI Map	5	52.48	RGD
Cytogenetic Map	5	q32	UniSTS

BF389091

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	104,410,894 - 104,411,055 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	108,273,219 - 108,273,379	NCBI	Rnor6.0
Rnor_5.0	5	112,238,274 - 112,238,434	UniSTS	Rnor5.0
RGSC_v3.4	5	109,332,769 - 109,332,929	UniSTS	RGSC3.4
Celera	5	103,116,755 - 103,116,915	UniSTS
RH 3.4 Map	5	745.5	UniSTS
Cytogenetic Map	5	q32	UniSTS

BF397897

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	104,422,245 - 104,422,380 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	108,284,570 - 108,284,704	NCBI	Rnor6.0
Rnor_5.0	5	112,249,625 - 112,249,759	UniSTS	Rnor5.0
RGSC_v3.4	5	109,344,120 - 109,344,254	UniSTS	RGSC3.4
Celera	5	103,128,110 - 103,128,244	UniSTS
RH 3.4 Map	5	745.5	UniSTS
Cytogenetic Map	5	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
6	11	38	128	47	45	18	22	18	6	141	84	3	107	25	89	27	13	13

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000038972 ⟹ ENSRNOP00000032876

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	109,531,586 - 109,538,246 (+)	Ensembl
mRatBN7.2 Ensembl	5	104,415,893 - 104,422,433 (+)	Ensembl
Rnor_6.0 Ensembl	5	108,278,217 - 108,284,757 (+)	Ensembl

RefSeq Acc Id:

NM_001107945 ⟹ NP_001101415

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	109,531,704 - 109,538,244 (+)	NCBI
mRatBN7.2	5	104,415,893 - 104,422,433 (+)	NCBI
Rnor_6.0	5	108,278,217 - 108,284,757 (+)	NCBI
Rnor_5.0	5	112,243,272 - 112,249,812 (+)	NCBI
RGSC_v3.4	5	109,337,767 - 109,344,307 (+)	RGD
Celera	5	103,121,749 - 103,128,297 (+)	RGD

Sequence:

show sequence

GTGCGTGGAGCAGGACAGCGGGACCTAGGCCGGTCCTCAGCGGATATCTCTACAGGGTCGCTCT
GGACAGCGCGCCCTTGCTGGTTTCCACTCCTCAGAAGCGACTTCTCACAATGGAGCAATTTCCT
CGTAGAGACCGCAGTGGCGGGTGCCGACCCCATCTGGGCCCAGGGCGGGCTGTTGCTCCCGCTT
CGGCTGCGCGGTCGGTGTCGTCGGGGATCCCGGTGTCCGCGACTTTCCTAAGGCCGCCTGGCCT
TTTTCTGCGATCCACCGCAAGTGCGGGTCGCGCAGGATGCGTTCCGGGTCCTGGGCTGGATAGG
GCGTTGGGGGCGGTGGGCTGCGGCTACCCGCGGACCCCGAAGTGCGCCCGTTGTCGCAACCATG
GCGTGGTGTCAGCGCTCAAGGGCCACAAGCGCTTCTGCCGCTGGCGGGACTGCGCGTGTGCCAA
GTGCACCCTGATCGCCGAGCGCCAGCGTGTCATGGCCGCGCAGGTGGCGCTGCGCAGGCAGCAG
GCGCAGGAGGAGAGCGAGGCCCGTGGGCTGCACAGGCTCCTGTACCAGGGGCCATCGGGGCCCG
GGGCTCCAGCCTCGGGGGGCAGCGGCAGGACCGAGAGTCCCCAGGTTTTGAGTAGCCCCATGAC
TGTAGCTGCTCTGGGAGCGGGTGCCTCTAGACACCCTGGGAGCCGGTCTGTCCCAGCTTTCGAG
GTTTTCCAGCAAGATTTTGCTGAGAGAAAGCAGGAACCAAAACAGAGTAACTGTGAGTCATGCC
AGAGTAGACACGAAGAACCAGTCTCCAACACTCATCACCGTTCTCCGGGATCATCTAACGGTAA
TGTTACCATGGAGAAACAGGGCTTCATGTCATCTATTTCAGAACAGTCGGACAAATCGACCATC
ATCCTGTCTCCTTGCCCCACGGATCAGTCAGGAGGAGAAGACAGCCCCAGGTCCTTCTCTTCCT
CTGACCTGGAATCAGGGAATGAAAGCGAGTGGGCCAGAGACTACACTGCTACCACAGCCAGCCT
TTCCACGGTGACCTCAAGACCACGAGACCCTCTCGGAATTCTTACCAGGATTTTTCCAGGTTAC
AAGCGTAGCCGCTTAGAAGGCATCCTACAGTTCTGCAAGGGAGATGTAGTCCAAGCCATTGAAC
AGATCTTAAATGGGAAAGAACATAAGCCAGACTGCAGGGACCTAGCACATGCAGACTTGGAAAA
TGCAGCCTTTCAGAGGGCTTCAGATTTTAGTCTTGCTGGCATTGGCTTTGGGACTCTAAATAAT
AAATCAGCTCTCTCTCCTCTTGAAGCTGCGTCTGCTGCTTACGGAGGAGATTCATCTCTCTACA
GTTTCAATCCTAGGCTAGCTTTCAGCCCACTGCGCCTGGCATATTCTTCTCCAGGAAGAGCACT
GTCTGGTTTTATGTCGCCTTACCTAACGCCTGGACTCGTTCCAGCATTGCCTTTTCGGCCAACT
TTGGATTATGCATTTCCAGGGATGATTAGGGAGCCGCCCCACCTTCCTAGCAAACATTTAGTAA
CTGGTGGTAGACTGTATTTCAGGCCCAATCAGGAGCACCTGTAACATATTCACTCTACCATTCT
GTGGTGTTTCTGGAGCCATGCAACACATACACACACAGGCACGCACACACGCATGTACGCACAC
ACCCTTATTAATGTACTTCAAAGAGCATAAGAATGACCTCTCAGTCTTAATTGCTATTTTTCTA
AGCAGTGTAATATATTTTAGATTTTCTTTAGCATTTATTAAATCAAAAAGCATTTAATCATTAT
ATATGCCTTGAATAAACTTATTTCAGGAAATACTATTATTTTAAACTAATGAATTTTCTCCCTA
AATTATCACTTTTATTATAAAGTCATACATGCTTTTATTTTATTGTACAGTTGGGGTTATAGTT
GTGAACATGTGTAAAAAGAAATTCGTATGGCAGAATATGAACCAGGAGTGGGAGATTGTGGTTA
TTATTCTAAAACAACTCTATCTTCCCCTCTTCCTTTTTCCCTCCCGTCTTTTCCTCCTCCACCA
CAGATGAGCCAGAAATTGTTCCAAGTATTTAAAAACATTTTATTTGCTGATAAATGACCAATAG
TAAGCAATCCTAATAAATTTGAATATATTTTTTGGAATGTCCGTTTTTGTACTCTTTAGCTACT
ATTTGTAGAAAGGAAATATTTTTGAATGTTCTCTTTAAAGTTATTGTAAATGCACAAAGAACTT
TAGGGTCATAAGAAGCAAGACCCTGCCCTCTTCTGGCCACTATCACAAACTGCAATTCAGTTCT
GAGAAAACAAGTGGTTTTCTAACTGTTACAGACTAACACGTTTGTGAAGTAACCATTTTGGATC
ATGGTGTATTTATTTTCATGTTTTGAAATGTTTTCTCTTAAGGATAATTTTTGAGTAGCTTATG
CTTTTATCTGGGGATACAGTCCTTATCATTTGTTTTAGATAACTTGTCACCCATTCTCAAAGGT
AAGAAGAAATTATTCAACAACCAAGTTATCTGCTCAGATAAATATCTACTGATTCTATATAAAG
TATATTTAATGTATTTAGTAGAGACAAAATTTCCAAAGGTCAGTAAAACTTGCTGCCTTTAAAA
ACTTAGTGGTGTTCTAGAGTCTTAAGGCATCCATTTCTTTCCCCACCTGGAGCATTTAAAATCA
TCCATCTAGCATTTCAATTCAGCCACTGGGAAGCCCCAGGAAAAAACGGCTCATGGAACACCTG
TACAATGTTTTCCTCATGTGCCTTAAGTTTTAAACGGACAATGGCTTCACTGTATTGTGGAGAA
TAATGAAGACTCAGATGTGGTAGGAATTGGAGATATCTTTATCTGAGCAGCAAGAATCACTAGA
CATTTTTTAAAATTATTTTTACATATGTGTGTCCTTTCCACTAAGCTAATAAGTTTTCACAGTG
TATTTTACCAAAAAAAAAAAAAATCTAATGCATGACTGGAGAGTATCTCATGCTGATTTGGAAT
GCAACGTGTTTAACAATTTGCATAAATGTTAATGGAGCAGGATGGAGGAACAGTCTGTAAAATG
TAGGTGGATACACTGCTCACCTTTTGTGTGCAAAACAAAATGGAGAAACCCTTCAGGCTCAGAG
CCTGAATACTGTACGAAGTCTGGCAACCAATTGCTCTGCAGCCAACATATATTAAGATCAGACT
GATTTTGGATGATGGCTCTTTCAACCAAATGATTCTACCAAGTGGCCCGTTAGTACACGACTGT
GAGTAGTTTCCTGAGATTCTATGTCTCCTAAAATGTATTCAGATCAGGACACTTGGTGACCCTA
GAGTTGTTTTTATTTTATGAATCTACTATCTACATTCTATTTTTGAGATACAGTAGATCCTGTT
CAGGACGTCAAATGTACAGTATGATGTAAAGAGAGCTTTAGTAAATGGCAGAAATCTGGATGAA
AAGTACAGCAATTCTAGCATTGCTGGATTCTTCATAAAATTAACATAACAATGTGAGCATATTG
GCTGTGTGGTGATGGCCACCTTTAATCCCAGCATTCAGAAGGCAGAGGCAGATAAATCTCTAAG
TTAAAGGCCAGCCTGGTCTACAAAATGAGCTCCAGAACAGCCATGGCTACATAGAGAAACTCTG
TCTTAAAAACAAAACAAAACAAACAATAACAAAAACATGTGGACATATTATTTTAATTATCTAA
ATATTAAGTTAATTTTCATGATGCACTATATAGTCTAAACAATTCATACCACTCTTAAGACCTA
AATAACTTTATAAAATAGGAAATTCTTCCAACTACCAGCTAGACATTGAGGAAACCGAAGCTCA
GATCTGTATAATCAGTCCCAAGGGTAATAATAGTATGAGTTACCAGGAAGGCTTTCTTACTTTA
GTAATTTGAGACTGTTAGATATGAGAAAGGATTATGCATGTTTCGTTGCAGCTTTGTGTGGTGT
CTGATGCATAATATGTGGCAAATAGTACCTCATTATTTACTGATTAATAAAAGTATTAGATG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101415	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL97747	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032876
	ENSRNOP00000032876.4

RefSeq Acc Id:

NP_001101415 ⟸ NM_001107945

- UniProtKB:

D3ZIZ0 (UniProtKB/TrEMBL), A6JRF5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEQFPRRDRSGGCRPHLGPGRAVAPASAARSVSSGIPVSATFLRPPGLFLRSTASAGRAGCVPG
PGLDRALGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVA
LRRQQAQEESEARGLHRLLYQGPSGPGAPASGGSGRTESPQVLSSPMTVAALGAGASRHPGSRS
VPAFEVFQQDFAERKQEPKQSNCESCQSRHEEPVSNTHHRSPGSSNGNVTMEKQGFMSSISEQS
DKSTIILSPCPTDQSGGEDSPRSFSSSDLESGNESEWARDYTATTASLSTVTSRPRDPLGILTR
IFPGYKRSRLEGILQFCKGDVVQAIEQILNGKEHKPDCRDLAHADLENAAFQRASDFSLAGIGF
GTLNNKSALSPLEAASAAYGGDSSLYSFNPRLAFSPLRLAYSSPGRALSGFMSPYLTPGLVPAL
PFRPTLDYAFPGMIREPPHLPSKHLVTGGRLYFRPNQEHL

hide sequence

Ensembl Acc Id:

ENSRNOP00000032876 ⟸ ENSRNOT00000038972

Protein Domains

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZIZ0-F1-model_v2	AlphaFold	D3ZIZ0	1-488	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309796	AgrOrtholog
BioCyc Gene	G2FUF-40761	BioCyc
Ensembl Genes	ENSRNOG00000024093	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038972	ENTREZGENE
	ENSRNOT00000038972.6	UniProtKB/TrEMBL
Gene3D-CATH	4.10.1040.10	UniProtKB/TrEMBL
InterPro	DM_DNA-bd	UniProtKB/TrEMBL
	DM_DNA-bd_sf	UniProtKB/TrEMBL
	DMA	UniProtKB/TrEMBL
	DMRT/dsx/mab-3	UniProtKB/TrEMBL
	DMRT5_1_DMB_dom	UniProtKB/TrEMBL
	UBA-like	UniProtKB/TrEMBL
KEGG Report	rno:313352	UniProtKB/TrEMBL
NCBI Gene	313352	ENTREZGENE
PANTHER	DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A1	UniProtKB/TrEMBL
	PTHR12322	UniProtKB/TrEMBL
Pfam	DMA	UniProtKB/TrEMBL
	DMRT5_DMB	UniProtKB/TrEMBL
	PF00751	UniProtKB/TrEMBL
PhenoGen	Dmrta1	PhenoGen
PROSITE	DM_1	UniProtKB/TrEMBL
	DM_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000024093	RatGTEx
SMART	SM00301	UniProtKB/TrEMBL
Superfamily-SCOP	DM_DNA_bd	UniProtKB/TrEMBL
	UBA_like	UniProtKB/TrEMBL
UniProt	A6JRF5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZIZ0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-17	Dmrta1	DMRT-like family A1	Dmrta1	doublesex and mab-3 related transcription factor like family A1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Dmrta1	doublesex and mab-3 related transcription factor like family A1	Dmrta1_predicted	doublesex and mab-3 related transcription factor like family A1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Dmrta1_predicted	doublesex and mab-3 related transcription factor like family A1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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