Fbxw11 (F-box and WD repeat domain containing 11) - Rat Genome Database

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Gene: Fbxw11 (F-box and WD repeat domain containing 11) Rattus norvegicus
Analyze
Symbol: Fbxw11
Name: F-box and WD repeat domain containing 11
RGD ID: 1309121
Description: Predicted to enable several functions, including dynein complex binding activity; microtubule plus-end binding activity; and ubiquitin-like ligase-substrate adaptor activity. Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in several processes, including microtubule cytoskeleton organization; positive regulation of macromolecule metabolic process; and transport along microtubule. Predicted to act upstream of or within negative regulation of canonical NF-kappaB signal transduction; positive regulation of canonical NF-kappaB signal transduction; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in centrosome; cytosol; and nucleus. Predicted to be part of SCF ubiquitin ligase complex and microtubule associated complex. Predicted to be active in several cellular components, including cytoplasmic microtubule; kinetochore; and neuronal cell body. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: F-box and WD-40 domain protein 11; F-box/WD repeat-containing protein 11; LOC303024
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,737,181 - 17,834,834 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1017,720,444 - 17,834,834 (+)EnsemblGRCr8
mRatBN7.21017,232,735 - 17,330,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,227,181 - 17,330,571 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1021,981,943 - 22,079,366 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,470,550 - 21,567,952 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,958,675 - 17,056,257 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,542,374 - 17,640,718 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,542,374 - 17,640,718 (+)Ensemblrn6Rnor6.0
Rnor_5.01017,430,246 - 17,528,590 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41017,502,480 - 17,600,199 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1016,877,301 - 16,974,446 (+)NCBICelera
RGSC_v3.11017,503,612 - 17,599,012 (+)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11158290   PMID:11896578   PMID:14673179   PMID:16880511   PMID:16885022   PMID:18782782   PMID:18929646   PMID:19028597   PMID:19966869   PMID:20347421   PMID:21399614  


Genomics

Comparative Map Data
Fbxw11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,737,181 - 17,834,834 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1017,720,444 - 17,834,834 (+)EnsemblGRCr8
mRatBN7.21017,232,735 - 17,330,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,227,181 - 17,330,571 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1021,981,943 - 22,079,366 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,470,550 - 21,567,952 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,958,675 - 17,056,257 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,542,374 - 17,640,718 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,542,374 - 17,640,718 (+)Ensemblrn6Rnor6.0
Rnor_5.01017,430,246 - 17,528,590 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41017,502,480 - 17,600,199 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1016,877,301 - 16,974,446 (+)NCBICelera
RGSC_v3.11017,503,612 - 17,599,012 (+)NCBI
Cytogenetic Map10q12NCBI
FBXW11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385171,861,549 - 172,006,638 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5171,861,548 - 172,006,873 (-)Ensemblhg38GRCh38
GRCh375171,288,553 - 171,433,642 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365171,221,161 - 171,366,482 (-)NCBIBuild 36Build 36hg18NCBI36
Celera5167,321,013 - 167,466,463 (-)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5166,384,918 - 166,530,978 (-)NCBIHuRef
CHM1_15170,721,014 - 170,866,350 (-)NCBICHM1_1
T2T-CHM13v2.05172,401,847 - 172,546,952 (-)NCBIT2T-CHM13v2.0
Fbxw11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,592,595 - 32,696,816 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,592,724 - 32,696,816 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381132,642,555 - 32,746,816 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,642,724 - 32,746,816 (+)Ensemblmm10GRCm38
MGSCv371132,542,875 - 32,646,816 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361132,542,875 - 32,646,816 (+)NCBIMGSCv36mm8
Celera1135,097,954 - 35,164,258 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.02NCBI
Fbxw11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,687,493 - 24,834,345 (-)Ensembl
ChiLan1.0NW_00495540824,703,477 - 24,834,522 (-)NCBIChiLan1.0ChiLan1.0
FBXW11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24166,996,014 - 167,146,079 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15165,135,553 - 165,285,624 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05167,207,643 - 167,354,730 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15174,124,499 - 174,271,971 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5174,124,499 - 174,271,977 (-)EnsemblpanPan2panpan1.1
FBXW11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,238,695 - 40,363,445 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,238,737 - 40,361,125 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha440,187,588 - 40,312,355 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0440,613,819 - 40,738,727 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl440,613,835 - 40,738,782 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,429,468 - 40,554,217 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0440,619,623 - 40,744,342 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0441,129,822 - 41,254,632 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fbxw11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,508,434 - 94,619,239 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,256,657 - 3,341,994 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,256,658 - 3,341,918 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXW11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,212,607 - 52,337,913 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11652,212,401 - 52,337,893 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,561,220 - 56,654,277 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXW11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12374,015,964 - 74,154,285 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2374,015,964 - 74,154,062 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660344,473,459 - 4,624,970 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxw11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473317,985,546 - 18,121,398 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fbxw11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v195,488,288 - 5,584,910 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fbxw11
557 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:219
Count of miRNA genes:169
Interacting mature miRNAs:180
Transcripts:ENSRNOT00000064079
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
737823Alc12Alcohol consumption QTL 124.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101774978420796344Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101576223019737486Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat

Markers in Region
D10Rat182  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81017,749,784 - 17,749,933 (+)Marker Load Pipeline
mRatBN7.21017,245,513 - 17,245,662 (+)MAPPERmRatBN7.2
Rnor_6.01017,555,386 - 17,555,534NCBIRnor6.0
Rnor_5.01017,443,258 - 17,443,406UniSTSRnor5.0
RGSC_v3.41017,515,123 - 17,515,458RGDRGSC3.4
RGSC_v3.41017,515,215 - 17,515,363UniSTSRGSC3.4
Celera1016,890,021 - 16,890,169UniSTS
RGSC_v3.11017,516,172 - 17,516,507RGD
RH 2.0 Map10183.0RGD
SHRSP x BN Map1017.15RGD
Cytogenetic Map10q12UniSTS
RH142282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21017,330,378 - 17,330,548 (+)MAPPERmRatBN7.2
Rnor_6.01017,640,513 - 17,640,682NCBIRnor6.0
Rnor_5.01017,528,385 - 17,528,554UniSTSRnor5.0
RGSC_v3.41017,599,994 - 17,600,163UniSTSRGSC3.4
Celera1016,974,241 - 16,974,410UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001395595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000064079   ⟹   ENSRNOP00000059948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,737,184 - 17,834,818 (+)Ensembl
mRatBN7.2 Ensembl1017,232,953 - 17,330,571 (+)Ensembl
Rnor_6.0 Ensembl1017,542,374 - 17,640,718 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079698   ⟹   ENSRNOP00000069447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,798,683 - 17,834,834 (+)Ensembl
mRatBN7.2 Ensembl1017,294,414 - 17,330,440 (+)Ensembl
Rnor_6.0 Ensembl1017,579,284 - 17,640,693 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098062   ⟹   ENSRNOP00000082146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,803,925 - 17,834,834 (+)Ensembl
mRatBN7.2 Ensembl1017,299,656 - 17,330,571 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102539   ⟹   ENSRNOP00000079990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,737,185 - 17,834,819 (+)Ensembl
mRatBN7.2 Ensembl1017,227,181 - 17,330,571 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118219   ⟹   ENSRNOP00000091319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,737,197 - 17,834,834 (+)Ensembl
mRatBN7.2 Ensembl1017,227,326 - 17,330,571 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118897   ⟹   ENSRNOP00000097046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,737,197 - 17,834,834 (+)Ensembl
mRatBN7.2 Ensembl1017,232,989 - 17,330,571 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000136657   ⟹   ENSRNOP00000101191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,720,444 - 17,834,834 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000167115   ⟹   ENSRNOP00000109220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,737,356 - 17,834,834 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000170302   ⟹   ENSRNOP00000109654
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,737,183 - 17,834,833 (+)Ensembl
RefSeq Acc Id: NM_001395595   ⟹   NP_001382524
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,197 - 17,834,834 (+)NCBI
mRatBN7.21017,232,926 - 17,330,574 (+)NCBI
RefSeq Acc Id: NM_001395596   ⟹   NP_001382525
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,197 - 17,834,834 (+)NCBI
mRatBN7.21017,232,926 - 17,330,574 (+)NCBI
RefSeq Acc Id: NM_001414338   ⟹   NP_001401267
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,197 - 17,834,834 (+)NCBI
mRatBN7.21017,232,926 - 17,330,574 (+)NCBI
RefSeq Acc Id: XM_017597238   ⟹   XP_017452727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
mRatBN7.21017,232,957 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597240   ⟹   XP_017452729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,181 - 17,834,819 (+)NCBI
mRatBN7.21017,232,735 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597241   ⟹   XP_017452730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,181 - 17,834,819 (+)NCBI
mRatBN7.21017,232,735 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597243   ⟹   XP_017452732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
mRatBN7.21017,232,957 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597244   ⟹   XP_017452733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
mRatBN7.21017,232,957 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039085889   ⟹   XP_038941817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,189 - 17,834,819 (+)NCBI
mRatBN7.21017,232,735 - 17,330,564 (+)NCBI
RefSeq Acc Id: XM_039085890   ⟹   XP_038941818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
mRatBN7.21017,232,957 - 17,330,564 (+)NCBI
RefSeq Acc Id: XM_063268958   ⟹   XP_063125028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
RefSeq Acc Id: XP_017452727   ⟸   XM_017597238
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452732   ⟸   XM_017597243
- Peptide Label: isoform X5
- UniProtKB: D3ZXC6 (UniProtKB/TrEMBL),   A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452733   ⟸   XM_017597244
- Peptide Label: isoform X6
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452729   ⟸   XM_017597240
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452730   ⟸   XM_017597241
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069447   ⟸   ENSRNOT00000079698
Ensembl Acc Id: ENSRNOP00000059948   ⟸   ENSRNOT00000064079
RefSeq Acc Id: XP_038941817   ⟸   XM_039085889
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GIW9 (UniProtKB/TrEMBL),   A0A0G2JVE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941818   ⟸   XM_039085890
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZPA1 (UniProtKB/TrEMBL),   A0A8I5ZUE3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000091319   ⟸   ENSRNOT00000118219
Ensembl Acc Id: ENSRNOP00000082146   ⟸   ENSRNOT00000098062
Ensembl Acc Id: ENSRNOP00000079990   ⟸   ENSRNOT00000102539
Ensembl Acc Id: ENSRNOP00000097046   ⟸   ENSRNOT00000118897
RefSeq Acc Id: NP_001382524   ⟸   NM_001395595
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401267   ⟸   NM_001414338
- Peptide Label: isoform 3
- UniProtKB: A0A8I5ZUE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001382525   ⟸   NM_001395596
- Peptide Label: isoform 2
- UniProtKB: A0A8I6GMC9 (UniProtKB/TrEMBL),   A0A0G2JVE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125028   ⟸   XM_063268958
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZUE3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109654   ⟸   ENSRNOT00000170302
Ensembl Acc Id: ENSRNOP00000101191   ⟸   ENSRNOT00000136657
Ensembl Acc Id: ENSRNOP00000109220   ⟸   ENSRNOT00000167115
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVE0-F1-model_v2 AlphaFold A0A0G2JVE0 1-531 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309121 AgrOrtholog
BioCyc Gene G2FUF-25621 BioCyc
Ensembl Genes ENSRNOG00000004395 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064079 ENTREZGENE
  ENSRNOT00000064079.4 UniProtKB/TrEMBL
  ENSRNOT00000079698.3 UniProtKB/TrEMBL
  ENSRNOT00000098062 ENTREZGENE
  ENSRNOT00000098062.2 UniProtKB/TrEMBL
  ENSRNOT00000102539 ENTREZGENE
  ENSRNOT00000102539.2 UniProtKB/TrEMBL
  ENSRNOT00000118219 ENTREZGENE
  ENSRNOT00000118219.2 UniProtKB/TrEMBL
  ENSRNOT00000118897 ENTREZGENE
  ENSRNOT00000118897.2 UniProtKB/TrEMBL
  ENSRNOT00000136657 ENTREZGENE
  ENSRNOT00000136657.1 UniProtKB/TrEMBL
  ENSRNOT00000167115 ENTREZGENE
  ENSRNOT00000167115.1 UniProtKB/TrEMBL
  ENSRNOT00000170302 ENTREZGENE
  ENSRNOT00000170302.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  6.10.250.1840 UniProtKB/TrEMBL
InterPro Beta-prop_TEP1_2nd UniProtKB/TrEMBL
  Beta-TrCP_D UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD-F-box_domain-protein UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene 303024 ENTREZGENE
PANTHER F-BOX AND WD REPEAT DOMAIN-CONTAINING 11-B UniProtKB/TrEMBL
  WD40 REPEAT PF20 UniProtKB/TrEMBL
Pfam Beta-prop_TEP1_2nd UniProtKB/TrEMBL
  Beta-TrCP_D UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Fbxw11 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004395 RatGTEx
SMART Beta-TrCP_D UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF81383 UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt A0A0G2JVE0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZPA1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZUE3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GIW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GMC9 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L034_RAT UniProtKB/TrEMBL
  A0ABK0LEL5_RAT UniProtKB/TrEMBL
  A0ABK0M0S1_RAT UniProtKB/TrEMBL
  D3ZXC6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-25 Fbxw11  F-box and WD repeat domain containing 11  Fbxw11  F-box and WD-40 domain protein 11   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Fbxw11  F-box and WD-40 domain protein 11   Fbxw11_predicted  F-box and WD-40 domain protein 11 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fbxw11_predicted  F-box and WD-40 domain protein 11 (predicted)      Symbol and Name status set to approved 70820 APPROVED