Tpst1 (tyrosylprotein sulfotransferase 1) - Rat Genome Database

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Gene: Tpst1 (tyrosylprotein sulfotransferase 1) Rattus norvegicus
Analyze
Symbol: Tpst1
Name: tyrosylprotein sulfotransferase 1
RGD ID: 1308473
Description: Predicted to enable protein homodimerization activity and protein-tyrosine sulfotransferase activity. Predicted to be involved in post-translational protein modification. Predicted to be located in Golgi membrane. Predicted to be active in Golgi lumen and trans-Golgi network. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human TPST1 (tyrosylprotein sulfotransferase 1); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC288617; MGC125193; protein-tyrosine sulfotransferase 1; TPST-1; tyrosylprotein sulfotransferase-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,180,688 - 32,247,478 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1232,180,936 - 32,241,821 (-)EnsemblGRCr8
mRatBN7.21226,544,536 - 26,605,706 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,544,536 - 26,605,704 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1227,692,616 - 27,753,470 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,303,130 - 28,363,985 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,364,920 - 27,425,024 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,045,753 - 30,112,377 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,045,751 - 30,106,893 (-)Ensemblrn6Rnor6.0
Rnor_5.01231,983,194 - 32,048,893 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41227,585,380 - 27,648,581 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1228,258,820 - 28,319,594 (-)NCBICelera
RGSC_v3.11227,448,607 - 27,511,801 (-)NCBI
Cytogenetic Map12q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
choline  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
cytarabine  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (EXP)
diuron  (EXP)
endosulfan  (EXP)
ethanol  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
glycidyl methacrylate  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
nefazodone  (EXP)
nitrates  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
tibolone  (ISO)
titanium dioxide  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi apparatus  (IBA,IEA,ISO)
Golgi lumen  (IEA,ISO)
Golgi membrane  (IEA,ISO,ISS)
trans-Golgi network  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Impact of Genetic Variation in MicroRNA-binding Site on Susceptibility to Colorectal Cancer. Kang BW, etal., Anticancer Res. 2016 Jul;36(7):3353-61.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9501187   PMID:12477932   PMID:15489334   PMID:16859706   PMID:17046811   PMID:28821720  


Genomics

Comparative Map Data
Tpst1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,180,688 - 32,247,478 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1232,180,936 - 32,241,821 (-)EnsemblGRCr8
mRatBN7.21226,544,536 - 26,605,706 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,544,536 - 26,605,704 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1227,692,616 - 27,753,470 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,303,130 - 28,363,985 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,364,920 - 27,425,024 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,045,753 - 30,112,377 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,045,751 - 30,106,893 (-)Ensemblrn6Rnor6.0
Rnor_5.01231,983,194 - 32,048,893 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41227,585,380 - 27,648,581 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1228,258,820 - 28,319,594 (-)NCBICelera
RGSC_v3.11227,448,607 - 27,511,801 (-)NCBI
Cytogenetic Map12q12NCBI
TPST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38766,198,790 - 66,360,443 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl766,205,289 - 66,420,549 (+)Ensemblhg38GRCh38
GRCh37765,670,321 - 65,825,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36765,307,750 - 65,462,865 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34765,114,463 - 65,269,579NCBI
Celera766,288,228 - 66,443,350 (-)NCBICelera
Cytogenetic Map7q11.21NCBI
HuRef761,856,837 - 62,012,019 (+)NCBIHuRef
CHM1_1765,765,874 - 65,920,745 (+)NCBICHM1_1
T2T-CHM13v2.0767,420,877 - 67,582,531 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2765,007,777 - 65,162,926 (+)NCBI
Tpst1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395130,102,167 - 130,164,575 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5130,102,167 - 130,164,570 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385130,073,326 - 130,135,734 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5130,073,326 - 130,135,729 (+)Ensemblmm10GRCm38
MGSCv375130,549,196 - 130,611,602 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365130,358,029 - 130,420,432 (+)NCBIMGSCv36mm8
Celera5127,079,934 - 127,142,580 (+)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map568.53NCBI
Tpst1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554568,520,906 - 8,618,107 (+)Ensembl
ChiLan1.0NW_0049554568,523,362 - 8,616,891 (+)NCBIChiLan1.0ChiLan1.0
TPST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2681,520,599 - 81,670,282 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17129,847,958 - 129,997,430 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0759,707,582 - 59,856,809 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1773,271,704 - 73,419,642 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl773,271,704 - 73,419,642 (+)EnsemblpanPan2panpan1.1
TPST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.16950,068 - 1,050,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl6905,637 - 1,055,080 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha62,608,899 - 2,750,367 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.06713,770 - 855,612 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl6611,487 - 855,471 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.16657,087 - 790,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.06650,999 - 792,726 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.06822,824 - 964,596 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tpst1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344126,443,739 - 126,539,126 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365437,497,424 - 7,565,483 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365437,497,431 - 7,592,790 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl316,407,609 - 16,585,485 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1316,407,607 - 16,525,788 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2316,660,057 - 16,771,040 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TPST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1281,925,002 - 2,065,405 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl281,925,056 - 2,065,632 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607014,573,481 - 14,714,049 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpst1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247408,503,484 - 8,588,004 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247408,479,113 - 8,587,942 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tpst1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11623,850,190 - 23,910,359 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tpst1
528 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:352
Count of miRNA genes:129
Interacting mature miRNAs:135
Transcripts:ENSRNOT00000001200, ENSRNOT00000065868
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122977552242298555Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)122963663737764351Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat

Markers in Region
AU048323  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21226,575,214 - 26,575,340 (+)MAPPERmRatBN7.2
Rnor_6.01230,076,431 - 30,076,556NCBIRnor6.0
Rnor_5.01232,012,946 - 32,013,071UniSTSRnor5.0
RGSC_v3.41227,616,792 - 27,616,917UniSTSRGSC3.4
Celera1228,289,140 - 28,289,265UniSTS
Cytogenetic Map12q13UniSTS
RH136945  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21226,544,608 - 26,544,810 (+)MAPPERmRatBN7.2
Rnor_6.01230,045,826 - 30,046,027NCBIRnor6.0
Rnor_5.01231,983,267 - 31,983,468UniSTSRnor5.0
RGSC_v3.41227,585,217 - 27,585,418UniSTSRGSC3.4
Celera1228,258,657 - 28,258,858UniSTS
RH 3.4 Map12451.2UniSTS
Cytogenetic Map12q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001200   ⟹   ENSRNOP00000001200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1232,181,820 - 32,241,821 (-)Ensembl
mRatBN7.2 Ensembl1226,544,536 - 26,605,704 (-)Ensembl
Rnor_6.0 Ensembl1230,046,001 - 30,106,893 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000065868   ⟹   ENSRNOP00000060104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1232,180,936 - 32,241,821 (-)Ensembl
mRatBN7.2 Ensembl1226,544,634 - 26,605,704 (-)Ensembl
Rnor_6.0 Ensembl1230,046,001 - 30,106,889 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084968   ⟹   ENSRNOP00000070504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1232,180,974 - 32,241,821 (-)Ensembl
mRatBN7.2 Ensembl1226,544,541 - 26,605,644 (-)Ensembl
Rnor_6.0 Ensembl1230,045,751 - 30,083,824 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000148267   ⟹   ENSRNOP00000104549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1232,202,860 - 32,241,821 (-)Ensembl
RefSeq Acc Id: NM_001011903   ⟹   NP_001011903
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,180,924 - 32,241,821 (-)NCBI
mRatBN7.21226,544,772 - 26,605,675 (-)NCBI
Rnor_6.01230,045,989 - 30,106,889 (-)NCBI
Rnor_5.01231,983,194 - 32,048,893 (-)NCBI
RGSC_v3.41227,585,380 - 27,648,581 (-)RGD
Celera1228,258,820 - 28,319,594 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249234   ⟹   XP_006249296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,180,688 - 32,241,889 (-)NCBI
mRatBN7.21226,544,536 - 26,605,706 (-)NCBI
Rnor_6.01230,045,753 - 30,106,819 (-)NCBI
Rnor_5.01231,983,194 - 32,048,893 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063271164   ⟹   XP_063127234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81232,180,688 - 32,247,478 (-)NCBI
RefSeq Acc Id: NP_001011903   ⟸   NM_001011903
- UniProtKB: Q3KR92 (UniProtKB/Swiss-Prot),   A6J0M9 (UniProtKB/TrEMBL),   Q6AYS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249296   ⟸   XM_006249234
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QSG0 (UniProtKB/TrEMBL),   Q6AYS9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070504   ⟸   ENSRNOT00000084968
Ensembl Acc Id: ENSRNOP00000060104   ⟸   ENSRNOT00000065868
Ensembl Acc Id: ENSRNOP00000001200   ⟸   ENSRNOT00000001200
RefSeq Acc Id: XP_063127234   ⟸   XM_063271164
- Peptide Label: isoform X1
- UniProtKB: Q3KR92 (UniProtKB/Swiss-Prot),   A6J0M9 (UniProtKB/TrEMBL),   Q6AYS9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000104549   ⟸   ENSRNOT00000148267

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3KR92-F1-model_v2 AlphaFold Q3KR92 1-370 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698583
Promoter ID:EPDNEW_R9103
Type:multiple initiation site
Name:Tpst1_1
Description:tyrosylprotein sulfotransferase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01230,106,911 - 30,106,971EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308473 AgrOrtholog
BioCyc Gene G2FUF-19524 BioCyc
Ensembl Genes ENSRNOG00000000900 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001200 ENTREZGENE
  ENSRNOT00000001200.6 UniProtKB/Swiss-Prot
  ENSRNOT00000065868 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7106945 IMAGE-MGC_LOAD
  IMAGE:7381985 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  TPST UniProtKB/Swiss-Prot
KEGG Report rno:288617 UniProtKB/Swiss-Prot
MGC_CLONE MGC:125193 IMAGE-MGC_LOAD
  MGC:93723 IMAGE-MGC_LOAD
NCBI Gene 288617 ENTREZGENE
PANTHER PROTEIN-TYROSINE SULFOTRANSFERASE 1 UniProtKB/Swiss-Prot
  PTHR12788 UniProtKB/Swiss-Prot
Pfam Sulfotransfer_3 UniProtKB/Swiss-Prot
PhenoGen Tpst1 PhenoGen
RatGTEx ENSRNOG00000000900 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8L2QSG0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R3F8_RAT UniProtKB/TrEMBL
  A0ABK0LS35_RAT UniProtKB/TrEMBL
  A6J0M9 ENTREZGENE, UniProtKB/TrEMBL
  Q3KR92 ENTREZGENE
  Q6AYS9 ENTREZGENE, UniProtKB/TrEMBL
  TPST1_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-06 Tpst1  tyrosylprotein sulfotransferase 1  Tpst1  protein-tyrosine sulfotransferase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Tpst1  protein-tyrosine sulfotransferase 1  Tpst1  tyrosylprotein sulfotransferase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tpst1  tyrosylprotein sulfotransferase 1  Tpst1_predicted  tyrosylprotein sulfotransferase 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tpst1_predicted  tyrosylprotein sulfotransferase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED