Advanced Search (OLGA)

Gene: Epc2 (enhancer of polycomb 2) Rattus norvegicus

Analyze

Symbol:

Epc2

Name:

enhancer of polycomb 2 (Ensembl:enhancer of polycomb homolog 2)

RGD ID:

1307271

Description:

Predicted to be involved in positive regulation of double-strand break repair via homologous recombination; regulation of cell cycle; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex; nucleosome; and piccolo histone acetyltransferase complex. Orthologous to human EPC2 (enhancer of polycomb homolog 2); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; INTERACTS WITH 6-propyl-2-thiouracil; amitrole; atrazine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

enhancer of polycomb homolog 2; enhancer of polycomb homolog 2 (Drosophila); LOC362132

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EPC2 (enhancer of polycomb 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Epc2 (enhancer of polycomb homolog 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Epc2 (enhancer of polycomb 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EPC2 (enhancer of polycomb 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EPC2 (enhancer of polycomb homolog 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Epc2 (enhancer of polycomb 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EPC2 (enhancer of polycomb homolog 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EPC2 (enhancer of polycomb 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Epc2 (enhancer of polycomb 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Epc2 (enhancer of polycomb 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CARD19 (caspase recruitment domain family member 19)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	EPC2 (enhancer of polycomb 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Epc2 (enhancer of polycomb homolog 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	epc2 (enhancer of polycomb homolog 2 (Drosophila))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	EPL1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	EPL1	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	E(Pc)	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	E(Pc)	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	epc-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	epc-1	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	epc2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	54,276,187 - 54,376,373 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	54,276,239 - 54,376,916 (+)	Ensembl				GRCr8
mRatBN7.2	3	33,867,219 - 33,967,908 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	33,867,219 - 33,967,150 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	37,245,306 - 37,338,792 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	45,830,029 - 45,923,519 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	43,642,087 - 43,735,614 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	33,641,616 - 33,741,219 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	33,641,616 - 33,740,461 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	38,799,078 - 38,898,681 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	30,420,605 - 30,536,656 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	32,058,204 - 32,153,476 (+)	NCBI		Celera
RGSC_v3.1	3	30,316,765 - 30,433,028 (+)	NCBI
Cytogenetic Map	3	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

6-propyl-2-thiouracil (EXP)

amiodarone (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

caffeine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

diclofenac (ISO)

dimethyl sulfoxide (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

ethanol (ISO)

fluoranthene (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

gentamycin (EXP)

ibuprofen (ISO)

L-methionine (ISO)

leflunomide (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

N-methyl-4-phenylpyridinium (ISO)

oxaliplatin (EXP)

paracetamol (ISO)

pentachlorophenol (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

propanal (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

testosterone (ISO)

tetrachloroethene (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

chromatin organization (IBA,IEA)

DNA-templated transcription (IEA)

positive regulation of double-strand break repair via homologous recombination (ISO)

regulation of cell cycle (ISO)

regulation of transcription by RNA polymerase II (IBA,IEA)

Cellular Component

NuA4 histone acetyltransferase complex (IBA,IEA)

nucleus (IEA)

piccolo histone acetyltransferase complex (IBA)

Molecular Function

protein-macromolecule adaptor activity (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

INO80 family mediated chromatin remodeling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Comprehensive gene review and curation	RGD comprehensive gene curation
5.	The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics.	Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.

Genomics

Comparative Map Data

Epc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	54,276,187 - 54,376,373 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	54,276,239 - 54,376,916 (+)	Ensembl				GRCr8
mRatBN7.2	3	33,867,219 - 33,967,908 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	33,867,219 - 33,967,150 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	37,245,306 - 37,338,792 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	45,830,029 - 45,923,519 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	43,642,087 - 43,735,614 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	33,641,616 - 33,741,219 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	33,641,616 - 33,740,461 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	38,799,078 - 38,898,681 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	30,420,605 - 30,536,656 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	32,058,204 - 32,153,476 (+)	NCBI		Celera
RGSC_v3.1	3	30,316,765 - 30,433,028 (+)	NCBI
Cytogenetic Map	3	q12	NCBI

EPC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	148,644,751 - 148,787,569 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	148,644,440 - 148,788,609 (+)	Ensembl			hg38	GRCh38
GRCh37	2	149,402,320 - 149,545,138 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	149,119,038 - 149,261,606 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	149,236,299 - 149,378,867	NCBI
Celera	2	143,116,707 - 143,259,286 (+)	NCBI		Celera
Cytogenetic Map	2	q23.1	NCBI
HuRef	2	141,400,948 - 141,543,639 (+)	NCBI		HuRef
CHM1_1	2	149,408,018 - 149,550,591 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	149,095,135 - 149,237,987 (+)	NCBI		T2T-CHM13v2.0

Epc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	49,341,498 - 49,441,954 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	49,341,498 - 49,441,960 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	49,450,755 - 49,551,947 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	49,451,486 - 49,551,948 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	49,307,006 - 49,407,129 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	49,273,525 - 49,373,192 (+)	NCBI		MGSCv36	mm8
Celera	2	51,125,040 - 51,224,667 (+)	NCBI		Celera
Cytogenetic Map	2	C1.1	NCBI
cM Map	2	28.62	NCBI

Epc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955440	14,573,960 - 14,646,431 (+)	Ensembl
ChiLan1.0	NW_004955440	14,573,960 - 14,645,171 (+)	NCBI	ChiLan1.0	ChiLan1.0

EPC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	26,140,608 - 26,284,335 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	26,155,574 - 26,299,294 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	11,074,397 - 11,218,181 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	153,005,269 - 153,148,789 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	153,005,176 - 153,148,644 (+)	Ensembl			panPan2	panpan1.1

EPC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	19	50,356,490 - 50,484,405 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	19	50,416,340 - 50,482,878 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	19	50,480,600 - 50,607,918 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	19	51,829,735 - 51,957,381 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	19	51,839,014 - 51,956,581 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	19	50,474,115 - 50,601,906 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	19	50,609,141 - 50,736,678 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	19	52,016,983 - 52,134,906 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Epc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	112,991,745 - 113,128,877 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	28,488,377 - 28,625,975 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	28,489,620 - 28,625,975 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EPC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	3,417,063 - 3,526,171 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	3,417,446 - 3,526,223 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	2,980,941 - 3,121,134 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EPC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	34,046,966 - 34,190,829 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	34,047,028 - 34,191,956 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	165,321,145 - 165,465,454 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Epc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624866	1,301,584 - 1,452,825 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624866	1,301,922 - 1,451,847 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Epc2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	27,328,348 - 27,419,991 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Epc2
825 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	789
Count of miRNA genes:	310
Interacting mature miRNAs:	413
Transcripts:	ENSRNOT00000051953
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	51490129	111359995	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	53651826	98651826	Rat
1298073	Cm13	Cardiac mass QTL 13	2.5		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	45423609	58601291	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	48876619	93876619	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	48876619	93876619	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	37772258	55937853	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	28625339	67641995	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	35403199	97383526	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
631832	Sach1	Saccharin preference QTL 1	2.7	0.02	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	3	47904172	92904172	Rat
2313079	Bss73	Bone structure and strength QTL 73	1.5		tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	3	47904172	70710963	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	51092561	96092561	Rat
2313076	Bss74	Bone structure and strength QTL 74	2	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	3	47904172	70710963	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	15272348	60272348	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	36425116	81425116	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	48657744	93657744	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	37796919	82796919	Rat
2313093	Bmd77	Bone mineral density QTL 77	2.2	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	3	47904172	70710963	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	38708931	67641995	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	38708931	67641995	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	48657744	93657744	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	38708931	67641995	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	50766145	95766145	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	51092561	96092561	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	50766145	95766145	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	36721849	110333156	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	38708931	67641995	Rat
2313101	Bmd76	Bone mineral density QTL 76	3.6	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	3	47904172	70710963	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	38708931	67641995	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	38708931	67641995	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	38708931	67641995	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	48657744	93657744	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	42158111	124558371	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
2325840	Bp345	Blood pressure QTL 345		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	38708931	83708931	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	48657744	93657744	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	37363734	82363734	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	36101403	81101403	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	48657744	93657744	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	42158111	124558371	Rat
2313049	Bss72	Bone structure and strength QTL 72	2.6	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	3	47904172	70710963	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	37796919	59119581	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat

Markers in Region

D2Ertd694e

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	33,966,836 - 33,967,038 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	33,740,148 - 33,740,349	NCBI	Rnor6.0
Rnor_5.0	3	38,897,610 - 38,897,811	UniSTS	Rnor5.0
RGSC_v3.4	3	30,536,343 - 30,536,544	UniSTS	RGSC3.4
Celera	3	32,153,163 - 32,153,364	UniSTS
Cytogenetic Map	3	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000051953 ⟹ ENSRNOP00000040649

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	54,276,239 - 54,376,349 (+)	Ensembl
mRatBN7.2 Ensembl	3	33,867,219 - 33,967,150 (+)	Ensembl
Rnor_6.0 Ensembl	3	33,641,616 - 33,740,461 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115060 ⟹ ENSRNOP00000083318

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	54,276,489 - 54,376,916 (+)	Ensembl
mRatBN7.2 Ensembl	3	33,867,219 - 33,967,150 (+)	Ensembl

RefSeq Acc Id:

NM_001108581 ⟹ NP_001102051

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	54,276,444 - 54,376,372 (+)	NCBI
mRatBN7.2	3	33,867,219 - 33,967,150 (+)	NCBI
Rnor_6.0	3	33,641,616 - 33,740,461 (+)	NCBI
Rnor_5.0	3	38,799,078 - 38,898,681 (+)	NCBI
RGSC_v3.4	3	30,420,605 - 30,536,656 (+)	RGD
Celera	3	32,058,204 - 32,153,476 (+)	RGD

Sequence:

show sequence

AGGCGGCGGGAGTGCTCCCCCCTCCCCGCCCGCCCCGCCGCCGCCGCCCGGGCTGTTCCTGTAA
GGCGGGGAGACAATGAGTAAACTCTCCTTCCGAGCGCGGGCGCTGGACGCCGCCAAACCGCTGC
CCATCTACCGCGGCAAGGACATGCCTGATCTCAACGACTGCGTCTCCATCAACCGGGCCGTGCC
CCAGATGCCCACCGGGATGGAGAAGGAGGAGGAATCGGAACATCACTTACAGCGAGCTATTTCA
GCACAGCAAGTATTTAGAGAAAAAAAAGAGAGCATGGTCATTCCAGTTCCTGAGGCGGAGAGCA
ACGTCAACTATTACAATCGCTTGTACAAAGGGGAGTTTAAACAGCCCAAACAGTTCATTCATAT
TCAGCCTTTTAACCTAGACAATGAGCAACCAGATTATGATATGGATTCTGAAGATGAGACATTA
TTAAATAGACTTAACAGAAAGATGGAAATTAAACCTTTGCAATTTGAAATTATGATTGACAGAC
TTGAAAAAGCCAGTTCTAACCAGCTTGTAACACTTCAAGAAGCAAAACTGCTGCTGAATGAAGA
CGACTACCTTATTAAAGCTGTATATGACTACTGGGTGAGGAAACGCAAGAACTGCAGGGGGCCG
TCCCTCATCCCCCAGATTAAGCAAGAGAAGAGAGATGGCTCTACCAACAATGATCCTTATGTTG
CCTTTCGGAGGAGAACAGAGAAGATGCAGACTCGGAAGAACCGTAAGAATGATGAGGCTTCTTA
TGAAAAGATGCTGAAGCTGAGGCGGGAGTTCAGCAGAGCCATAACAATTTTGGAAATGATTAAG
AGAAGAGAGAAAACCAAACGGGAATTATTGCACTTAACGCTGGAAGTTGTGGAAAAAAGATATC
ATTTGGGAGACTATGGGGGTGAAATCCTTAATGAAGTGAAAGTTAATAGATCAGAAAAAGAGTT
ATATGCCAGTCCAGCAACTCTTCATAATGGAAATCATCACAAAGTTCAAGAATGTAAAACTAAG
CACCCTCATCATTTGTCTTTGAAAGAAGAGGCTTCTGACGTGGTCCGTCAAAAGAAGAAGCACC
CCAAGAAGCCTAAGGCAGAGGCTGTGCTAGCCCCGCCGCAGCCCACTCCTGAGACAGTGCCTGT
GATCAATAAGAGTGACATTAAGCAATATGACTTTCAGAGCTCAGATGAAGATGAATTTCCACAG
GTACCATCTCCAGCATCAGAACCTGAAGAAGAAAATGATCCTGATGGTCCCTGTGCTTTCAGAA
GGCGGGCAGGATGCCAGTATTATGCTCCGCGTTTGGACCAAGCTAATAACCATCCGTGTGAAAG
TTCAGAGTTGGCAGACTTGGATAAGTTGAGGTATAAGCATTGTCTCACAACACTTACAGTTCCA
AGAAGATGTATAGGGTTTGCCAGGAGGCGAATTGGCAGGGGTGGAAGGGTCATAATGGACCGAA
TATCCACAGAACATGACCCCGTCCTAAAACAGATAGACCCTGAGATGCTGAATGGGCTTTCAAG
CTCTTCCCAAACTATAGACTTTTCTTCTAATTTCTCTCGGACCAATGCTTCCAGTAAACCTTGT
GAAAATAGACTGTCCCTTTCTGAAATATTAAGCAATATCAGATCATGTCGACTACAGTGTTTCC
AGCCAAGGCTACTAAATGTACAGGACATTGATAGTGAAGAATGTACCTCAAGAAAACCAGGGCA
GACTGTGAGCAGTAAAAGGGTTTCTGCAGCATCTGTAGCTTTATTGAACACCAGCAAGAACGGC
ATATCAGTCACAGGGGGCATCACAGAAGAGCAGTTTCAGACACATCAACAGCAGCTAGCTCAAA
TGCAAAGGCAGCAACTCGCGCAGCTTCAGCAGAAACAGCAATCCCAGCATTCCTCACAGCAGAC
ACATCCAAAAGCACAGGGCTCAAGCACCTCGGACTGTATGTCTAAAACACTTGACTCAGCCAGC
GCCCACTTTGCTGCATCTGCAGTGGTCAGTGCTCCTGTTCCAAGTCGCAGTGAGGGATCTAAGG
AACAGAACACTGGCCACAACAATATGAATGGTGTTGTCCAGCCTTCAGGACCCTCTAAAACATT
ATATTCCACCAATATGGCTTTATCATCCAGCCCAGGGATTTCAGCTGTACAGCTTGTAAGGACA
GTTGGCCACACTACTACAAACCACTTGATCCCAGCGTTGTGCACAAGCAGTCCTCAGACACTTC
CCATGAACAATTCCTGCCTGACCAATGCAGTGCACCTCAATAATGTCAGTGTTGTTTCTCCTGT
CAATGTGCATATCAATACACGGACTTCAGCACCATCGCCAACAGCCTTAAAACTTGCCACAGTT
GCTGCCAGTATGGACAGAGTGCCAAAGGTTACTCCCAGCAGTGCCATCAGCAGCATAGCCAGAG
AGAACCATGAACCAGAAAGACTGGGTTTAAATGGAATAGCAGAGACAACAGTAGCTATGGAAGT
GACATAACGTAAAGTGTGTGGCTTTGACCTGTGTGGACGGTTGCAGTCATTCATATTCCAGCGG
AATACAAAGGCGACACTCTGGATCACAGAGCAGAACAATGGACCCAAATGGAGTACAGTATACC
GGATGTTAAGTCGATGTATGATGTATATTTTGTAAAATTGGGAAAATCACTACCTTGTAAAATA
GTTTATTTGTATCATCAATATTATTTCTGTTACTTGAATAGTAGATATTCATCATCATGCTTTT
GCACTTGAATTTGCAACTGAATGGATTTTAAAAATAATTCTTTAATGGGATCATGAGCATGAAA
TGGGATCCTGCATCACTTGTTTTAACTATTTATTTTGCCATGTTTACATTTTGTATCTTGTAAA
AAAAAATAAATCCAACTTTGTGTCTAAAAAGTTAAAGATTCATAGCTAGGAAATGAAATTCTTG
TAATTTTTTTCTAAAGGAACTGTAAAGTTTTCACTTGGTTCATTTTGTTTCACAATTTGACTAG
ATGGACTTTTTGGTAAACACTTTAGTGGCATTTCACTGTCAAATACGACTTCAAGGCAAAATAG
TATTTTCTATTACTGTGCAGGGGAAAGGGATGGATCGATACATGCAAATTTAATGTAGTAACTC
ACTTTTCCATATATTTTGAATGTATATTTCTATTTATAATACCAGTTTATAAAAAATAATTACA
CAGAAAAAGTGGACTAGGAAATTATGCATCTAGCACATTTAAACTGTGCAGATATGAAAATTTT
TCATGGATTACATTTTATCTGAAGACTGCATATTTTAACTGGCTTTAAAACTGTAACACACCAC
ATAAAAGATATTTACCAGGTATGTATTGCATCATATCATTGCAATAATTATTGGAAGTCTATAT
ATCGAGCCATCCCAGGTTTTGGGAGGGGGGAGGGTTGTGGCAAGATTGTCTTTTCAATTTTGGA
GAGTTTTCCTGTGGCTACAAGGCAAGTAACGGGTTGGAAAACGTCTGACTGTAAGTGTTGGACA
CCTTCATAGTGTAGTGTTTTAGTGACTTTTTTATACGGTTCTTGTACATTAGATACGTGTAGTG
GTGTTTCAGAATGTTTGTTTATGCACTAGTTCAGACAACTTTCCCTGTTACTTGTTCTTGATAA
GTGAAACCTGCAGGGAAATAAAAAATACATATCAAAAC

hide sequence

RefSeq Acc Id:

XM_006234155 ⟹ XP_006234217

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	54,276,187 - 54,376,373 (+)	NCBI
mRatBN7.2	3	33,867,295 - 33,967,908 (+)	NCBI
Rnor_6.0	3	33,641,640 - 33,741,219 (+)	NCBI
Rnor_5.0	3	38,799,078 - 38,898,681 (+)	NCBI

Sequence:

show sequence

CCCGCCCGCCCCGCCGCCGCCGCCCGGGCTGTTCCTGTAAGGCGGGGAGACAATGAGTAAACTC
TCCTTCCGAGCGCGGGCGCTGGACGCCGCCAAACCGCTGCCCATCTACCGCGGCAAGGACATGC
CTGATCTCAACGACTGCGTCTCCATCAACCGGGCCGTGCCCCAGATGCCCACCGGGATGGAGAA
GGAGGAGGAATCGGAACATCACTTACAGCGAGCTATTTCAGCACAGCAAGTATTTAGAGAAAAA
AAAGAGAGCATGGTCATTCCAGTTCCTGAGGCGGAGAGCAACGTCAACTATTACAATCGCTTGT
ACAAAGGGGAGTTTAAACAGCCCAAACAGTTCATTCATATTCAGCCTTTTAACCTAGACAATGA
GCAACCAGATTATGATATGGATTCTGAAGATGAGACATTATTAAATAGACTTAACAGAAAGATG
GAAATTAAACCTTTGCAATTTGAAATTATGATTGACAGACTTGAAAAAGCCAGTTCTAACCAGC
TTGTAACACTTCAAGAAGCAAAACTGCTGCTGAATGAAGACGACTACCTTATTAAAGCTGTATA
TGACTACTGGGTGAGGAAACGCAAGAACTGCAGGGGGCCGTCCCTCATCCCCCAGATTAAGCAA
GAGAAGAGAGATGGCTCTACCAACAATGATCCTTATGTTGCCTTTCGGAGGAGAACAGAGAAGA
TGCAGACTCGGAAGAACCGTAAGAATGATGAGGCTTCTTATGAAAAGATGCTGAAGCTGAGGCG
GGAGTTCAGCAGAGCCATAACAATTTTGGAAATGATTAAGAGAAGAGAGAAAACCAAACGGGAA
TTATTGCACTTAACGCTGGAAGTTGTGGAAAAAAGATATCATTTGGGAGACTATGGGGGTGAAA
TCCTTAATGAAGTGAAAGTTAATAGATCAGAAAAAGAGTTATATGCCAGTCCAGCAACTCTTCA
TAATGGAAATCATCACAAAGTTCAAGAATGTAAAACTAAGGTACCATCTCCAGCATCAGAACCT
GAAGAAGAAAATGATCCTGATGGTCCCTGTGCTTTCAGAAGGCGGGCAGGATGCCAGTATTATG
CTCCGCGTTTGGACCAAGCTAATAACCATCCGTGTGAAAGTTCAGAGTTGGCAGACTTGGATAA
GTTGAGGTATAAGCATTGTCTCACAACACTTACAGTTCCAAGAAGATGTATAGGGTTTGCCAGG
AGGCGAATTGGCAGGGGTGGAAGGGTCATAATGGACCGAATATCCACAGAACATGACCCCGTCC
TAAAACAGATAGACCCTGAGATGCTGAATGGGCTTTCAAGCTCTTCCCAAACTATAGACTTTTC
TTCTAATTTCTCTCGGACCAATGCTTCCAGTAAACCTTGTGAAAATAGACTGTCCCTTTCTGAA
ATATTAAGCAATATCAGATCATGTCGACTACAGTGTTTCCAGCCAAGGCTACTAAATGTACAGG
ACATTGATAGTGAAGAATGTACCTCAAGAAAACCAGGGCAGACTGTGAGCAGTAAAAGGGTTTC
TGCAGCATCTGTAGCTTTATTGAACACCAGCAAGAACGGCATATCAGTCACAGGGGGCATCACA
GAAGAGCAGTTTCAGACACATCAACAGCAGCTAGCTCAAATGCAAAGGCAGCAACTCGCGCAGC
TTCAGCAGAAACAGCAATCCCAGCATTCCTCACAGCAGACACATCCAAAAGCACAGGGCTCAAG
CACCTCGGACTGTATGTCTAAAACACTTGACTCAGCCAGCGCCCACTTTGCTGCATCTGCAGTG
GTCAGTGCTCCTGTTCCAAGTCGCAGTGAGGGATCTAAGGAACAGAACACTGGCCACAACAATA
TGAATGGTGTTGTCCAGCCTTCAGGACCCTCTAAAACATTATATTCCACCAATATGGCTTTATC
ATCCAGCCCAGGGATTTCAGCTGTACAGCTTGTAAGGACAGTTGGCCACACTACTACAAACCAC
TTGATCCCAGCGTTGTGCACAAGCAGTCCTCAGACACTTCCCATGAACAATTCCTGCCTGACCA
ATGCAGTGCACCTCAATAATGTCAGTGTTGTTTCTCCTGTCAATGTGCATATCAATACACGGAC
TTCAGCACCATCGCCAACAGCCTTAAAACTTGCCACAGTTGCTGCCAGTATGGACAGAGTGCCA
AAGGTTACTCCCAGCAGTGCCATCAGCAGCATAGCCAGAGAGAACCATGAACCAGAAAGACTGG
GTTTAAATGGAATAGCAGAGACAACAGTAGCTATGGAAGTGACATAACGTAAAGTGTGTGGCTT
TGACCTGTGTGGACGGTTGCAGTCATTCATATTCCAGCGGAATACAAAGGCGACACTCTGGATC
ACAGAGCAGAACAATGGACCCAAATGGAGTACAGTATACCGGATGTTAAGTCGATGTATGATGT
ATATTTTGTAAAATTGGGAAAATCACTACCTTGTAAAATAGTTTATTTGTATCATCAATATTAT
TTCTGTTACTTGAATAGTAGATATTCATCATCATGCTTTTGCACTTGAATTTGCAACTGAATGG
ATTTTAAAAATAATTCTTTAATGGGATCATGAGCATGAAATGGGATCCTGCATCACTTGTTTTA
ACTATTTATTTTGCCATGTTTACATTTTGTATCTTGTAAAAAAAAATAAATCCAACTTTGTGTC
TAAAAAGTTAAAGATTCATAGCTAGGAAATGAAATTCTTGTAATTTTTTTCTAAAGGAACTGTA
AAGTTTTCACTTGGTTCATTTTGTTTCACAATTTGACTAGATGGACTTTTTGGTAAACACTTTA
GTGGCATTTCACTGTCAAATACGACTTCAAGGCAAAATAGTATTTTCTATTACTGTGCAGGGGA
AAGGGATGGATCGATACATGCAAATTTAATGTAGTAACTCACTTTTCCATATATTTTGAATGTA
TATTTCTATTTATAATACCAGTTTATAAAAAATAATTACACAGAAAAAGTGGACTAGGAAATTA
TGCATCTAGCACATTTAAACTGTGCAGATATGAAAATTTTTCATGGATTACATTTTATCTGAAG
ACTGCATATTTTAACTGGCTTTAAAACTGTAACACACCACATAAAAGATATTTACCAGGTATGT
ATTGCATCATATCATTGCAATAATTATTGGAAGTCTATATATCGAGCCATCCCAGGTTTTGGGA
GGGGGGAGGGTTGTGGCAAGATTGTCTTTTCAATTTTGGAGAGTTTTCCTGTGGCTACAAGGCA
AGTAACGGGTTGGAAAACGTCTGACTGTAAGTGTTGGACACCTTCATAGTGTAGTGTTTTAGTG
ACTTTTTTATACGGTTCTTGTACATTAGATACGTGTAGTGGTGTTTCAGAATGTTTGTTTATGC
ACTAGTTCAGACAACTTTCCCTGTTACTTGTTCTTGATAAGTGAAACCTGCAGGGAAATAAAAA
ATACATATCAAAACACGGCCATGCTGCATATGTGTTTATTTCACCATGTGCACACAGTGTGAGC
GAGGACAGGAGGGACAGGCCGGCACGTGCAGCACATGTCCCCCCAGGCTTTCCTGGCATTGAGG
AGAAGGTCTAAGGCTCATCCCTGGGCTCGATTGGGTTTCAGATAATCCAATATAAACTACCTTT
GCTATGAAAGTTCTTAAACTATTTTACAGAATGTAAGTAATTTGCAGTATAGCAGTCATTGAAA
TCTCATAAATGAGCCTCCTTTTATAAGTAAATAGAGTATAGTGTAGAATTATATTGCGAGGGGG
TTTTGGAAGTCCTGGGAAATGTAAATATTTTTAATGAATATGATTAAAACCATTTCAAACCAAA
CATAATTTTATACCGTTTTTATATCTGCAGTCCTGAAAGTTGTAAACTTATTGTCAGTTAAATT
AATGGGCCAGGATTTCTGCTGAGAGTGGTTTTTATTCAGATCCTAAATGTAAAGCAATTTATGG
TCAAAACCACAGGGGGAAAAATAAATTTAATGACTTTGTCGGTTGTGACCTGATAGGATCCATG
CTCGTTTTTGCCATACTACCTCTGGGGTTCACTGCTGATGATATAAAGGAAATAACTTGATTGA
TATGTATATGACTGTGTTCATTCTGCTTACAGTTGGATGTATCTTGCTATTAAGAATTTGAAAC
AACTCAGTGCTAATTTCAGAGAAAGCTTCTCCCCTCCCCCATTTCGCTGAAGTAAAGCATGAAG
TTAA

hide sequence

RefSeq Acc Id:

XM_063284106 ⟹ XP_063140176

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	54,276,187 - 54,376,373 (+)	NCBI

RefSeq Acc Id:

XM_063284107 ⟹ XP_063140177

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	54,276,187 - 54,376,373 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102051	(Get FASTA)	NCBI Sequence Viewer
	XP_006234217	(Get FASTA)	NCBI Sequence Viewer
	XP_063140176	(Get FASTA)	NCBI Sequence Viewer
	XP_063140177	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM00465	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000040649
	ENSRNOP00000040649.3
	ENSRNOP00000083318
	ENSRNOP00000083318.1

RefSeq Acc Id:

NP_001102051 ⟸ NM_001108581

- UniProtKB:

D4ADG5 (UniProtKB/TrEMBL), A6JEZ5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQV
FREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRL
NRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIP
QIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREK
TKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRSEKELYASPATLHNGNHHKVQECKTKHPHH
LSLKEEASDVVRQKKKHPKKPKAEAVLAPPQPTPETVPVINKSDIKQYDFQSSDEDEFPQVPSP
ASEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCESSELADLDKLRYKHCLTTLTVPRRCI
GFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGLSSSSQTIDFSSNFSRTNASSKPCENRL
SLSEILSNIRSCRLQCFQPRLLNVQDIDSEECTSRKPGQTVSSKRVSAASVALLNTSKNGISVT
GGITEEQFQTHQQQLAQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFA
ASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALSSSPGISAVQLVRTVGHT
TTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASM
DRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT

hide sequence

RefSeq Acc Id:	XP_006234217 ⟸ XM_006234155
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5ZZ28 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQV FREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRL NRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRKNCRGPSLIP QIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREK TKRELLHLTLEVVEKRYHLGDYGGEILNEVKVNRSEKELYASPATLHNGNHHKVQECKTKVPSP ASEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCESSELADLDKLRYKHCLTTLTVPRRCI GFARRRIGRGGRVIMDRISTEHDPVLKQIDPEMLNGLSSSSQTIDFSSNFSRTNASSKPCENRL SLSEILSNIRSCRLQCFQPRLLNVQDIDSEECTSRKPGQTVSSKRVSAASVALLNTSKNGISVT GGITEEQFQTHQQQLAQMQRQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFA ASAVVSAPVPSRSEGSKEQNTGHNNMNGVVQPSGPSKTLYSTNMALSSSPGISAVQLVRTVGHT TTNHLIPALCTSSPQTLPMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASM DRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT hide sequence

Ensembl Acc Id:

ENSRNOP00000040649 ⟸ ENSRNOT00000051953

Ensembl Acc Id:

ENSRNOP00000083318 ⟸ ENSRNOT00000115060

RefSeq Acc Id:	XP_063140176 ⟸ XM_063284106
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063140177 ⟸ XM_063284107
- Peptide Label:	isoform X2

Protein Domains

Enhancer of polycomb C-terminal Enhancer of polycomb-like N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ADG5-F1-model_v2	AlphaFold	D4ADG5	1-808	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307271	AgrOrtholog
BioCyc Gene	G2FUF-49762	BioCyc
Ensembl Genes	ENSRNOG00000029447	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000051953	ENTREZGENE
	ENSRNOT00000051953.5	UniProtKB/TrEMBL
	ENSRNOT00000115060	ENTREZGENE
	ENSRNOT00000115060.2	UniProtKB/TrEMBL
InterPro	E_Pc_C	UniProtKB/TrEMBL
	Enhancer_of_polycomb-like	UniProtKB/TrEMBL
	Enhancer_polycomb	UniProtKB/TrEMBL
KEGG Report	rno:362132	UniProtKB/TrEMBL
NCBI Gene	362132	ENTREZGENE
PANTHER	PTHR14898	UniProtKB/TrEMBL
Pfam	E_Pc_C	UniProtKB/TrEMBL
	EPL1	UniProtKB/TrEMBL
PhenoGen	Epc2	PhenoGen
RatGTEx	ENSRNOG00000029447	RatGTEx
UniProt	A0A8I5ZZ28	ENTREZGENE, UniProtKB/TrEMBL
	A6JEZ5	ENTREZGENE, UniProtKB/TrEMBL
	D4ADG5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2025-11-13	Epc2	enhancer of polycomb 2	Epc2	enhancer of polycomb homolog 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-11	Epc2	enhancer of polycomb homolog 2	Epc2	enhancer of polycomb homolog 2 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-11	Epc2	enhancer of polycomb homolog 2	Epc2	enhancer of polycomb homolog 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Epc2	enhancer of polycomb homolog 2 (Drosophila)	Epc2_predicted	enhancer of polycomb homolog 2 (Drosophila) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Epc2_predicted	enhancer of polycomb homolog 2 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - CTD

RGD Manual Annotations