EPC2 (enhancer of polycomb homolog 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: EPC2 (enhancer of polycomb homolog 2) Pan paniscus
Analyze
Symbol: EPC2
Name: enhancer of polycomb homolog 2
RGD ID: 11975114
Description: INVOLVED IN chromatin organization (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH autosomal dominant intellectual developmental disorder 1 (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21326,140,608 - 26,284,335 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B26,155,574 - 26,299,294 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B11,074,397 - 11,218,181 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B153,005,269 - 153,148,789 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B153,005,176 - 153,148,644 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EPC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21326,140,608 - 26,284,335 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B26,155,574 - 26,299,294 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B11,074,397 - 11,218,181 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B153,005,269 - 153,148,789 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B153,005,176 - 153,148,644 (+)Ensemblpanpan1.1panPan2
EPC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382148,644,751 - 148,787,569 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2148,644,440 - 148,787,569 (+)EnsemblGRCh38hg38GRCh38
GRCh372149,402,320 - 149,545,138 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362149,119,038 - 149,261,606 (+)NCBINCBI36Build 36hg18NCBI36
Build 342149,236,299 - 149,378,867NCBI
Celera2143,116,707 - 143,259,286 (+)NCBICelera
Cytogenetic Map2q23.1NCBI
HuRef2141,400,948 - 141,543,639 (+)NCBIHuRef
CHM1_12149,408,018 - 149,550,591 (+)NCBICHM1_1
T2T-CHM13v2.02149,095,135 - 149,237,987 (+)NCBIT2T-CHM13v2.0
Epc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39249,341,498 - 49,441,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl249,341,498 - 49,441,960 (+)EnsemblGRCm39 Ensembl
GRCm38249,450,755 - 49,551,947 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl249,451,486 - 49,551,948 (+)EnsemblGRCm38mm10GRCm38
MGSCv37249,307,006 - 49,407,129 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36249,273,525 - 49,373,192 (+)NCBIMGSCv36mm8
Celera251,125,040 - 51,224,667 (+)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map228.62NCBI
Epc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8354,276,187 - 54,376,373 (+)NCBIGRCr8
mRatBN7.2333,867,219 - 33,967,908 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl333,867,219 - 33,967,150 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx337,245,306 - 37,338,792 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0345,830,029 - 45,923,519 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0343,642,087 - 43,735,614 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0333,641,616 - 33,741,219 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl333,641,616 - 33,740,461 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0338,799,078 - 38,898,681 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4330,420,605 - 30,536,656 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1330,316,765 - 30,433,028 (+)NCBI
Celera332,058,204 - 32,153,476 (+)NCBICelera
Cytogenetic Map3q12NCBI
Epc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544014,573,960 - 14,646,431 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544014,573,960 - 14,645,171 (+)NCBIChiLan1.0ChiLan1.0
EPC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11950,356,490 - 50,484,405 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1950,416,340 - 50,482,878 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1950,480,600 - 50,607,918 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01951,829,735 - 51,957,381 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1951,839,014 - 51,956,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11950,474,115 - 50,601,906 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01950,609,141 - 50,736,678 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01952,016,983 - 52,134,906 (+)NCBIUU_Cfam_GSD_1.0
Epc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303112,991,745 - 113,128,877 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646928,488,377 - 28,625,975 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646928,489,620 - 28,625,975 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl153,417,063 - 3,526,171 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1153,417,446 - 3,526,223 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2152,980,941 - 3,121,134 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11034,046,966 - 34,190,829 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1034,047,028 - 34,191,956 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040165,321,145 - 165,465,454 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Epc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248661,301,584 - 1,452,825 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248661,301,922 - 1,451,847 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057430   ⟹   ENSPPAP00000034547
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B153,005,176 - 153,148,644 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057438   ⟹   ENSPPAP00000034555
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B153,005,309 - 153,051,813 (+)Ensembl
RefSeq Acc Id: XM_003816689   ⟹   XP_003816737
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21326,140,608 - 26,284,334 (-)NCBI
NHGRI_mPanPan12B26,155,574 - 26,299,293 (-)NCBI
Mhudiblu_PPA_v02B11,074,397 - 11,218,179 (-)NCBI
PanPan1.12B153,005,269 - 153,148,789 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034954023   ⟹   XP_034809914
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21326,140,608 - 26,284,335 (-)NCBI
NHGRI_mPanPan12B26,155,574 - 26,299,294 (-)NCBI
Mhudiblu_PPA_v02B11,074,397 - 11,218,181 (-)NCBI
RefSeq Acc Id: XM_034954024   ⟹   XP_034809915
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21326,140,608 - 26,284,334 (-)NCBI
NHGRI_mPanPan12B26,155,574 - 26,299,293 (-)NCBI
Mhudiblu_PPA_v02B11,074,397 - 11,218,179 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003816737 (Get FASTA)   NCBI Sequence Viewer  
  XP_034809914 (Get FASTA)   NCBI Sequence Viewer  
  XP_034809915 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034547
  ENSPPAP00000034547.1
  ENSPPAP00000034555.1
Reference Protein Sequences
RefSeq Acc Id: XP_003816737   ⟸   XM_003816689
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BXZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034809914   ⟸   XM_034954023
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034809915   ⟸   XM_034954024
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000034555   ⟸   ENSPPAT00000057438
RefSeq Acc Id: ENSPPAP00000034547   ⟸   ENSPPAT00000057430
Protein Domains
Enhancer of polycomb C-terminal   Enhancer of polycomb-like N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040114 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057430.1 UniProtKB/TrEMBL
  ENSPPAT00000057438.1 UniProtKB/TrEMBL
InterPro Enhancer_polycomb UniProtKB/TrEMBL
  Enhancer_polycomb-like_N UniProtKB/TrEMBL
  Enhancer_polycomb_C UniProtKB/TrEMBL
KEGG Report pps:100977128 UniProtKB/TrEMBL
NCBI Gene EPC2 ENTREZGENE
PANTHER ENHANCER OF POLYCOMB HOMOLOG 2 UniProtKB/TrEMBL
  PTHR14898 UniProtKB/TrEMBL
Pfam E_Pc_C UniProtKB/TrEMBL
  EPL1 UniProtKB/TrEMBL
UniProt A0A2R9BXZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C1B3_PANPA UniProtKB/TrEMBL