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Gene: Diras2 (DIRAS family GTPase 2) Rattus norvegicus

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Symbol:

Diras2

Name:

DIRAS family GTPase 2

RGD ID:

1305580

Description:

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human DIRAS2 (DIRAS family GTPase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

DIRAS family, GTP-binding RAS-like 2; GTP-binding protein Di-Ras2; LOC291006

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DIRAS2 (DIRAS family GTPase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Diras2 (DIRAS family, GTP-binding RAS-like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Diras2 (DIRAS family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DIRAS2 (DIRAS family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DIRAS2 (DIRAS family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Diras2 (DIRAS family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DIRAS2 (DIRAS family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DIRAS2 (DIRAS family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Diras2 (DIRAS family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Diras2 (DIRAS family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	DIRAS2 (DIRAS family GTPase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Diras2 (DIRAS family, GTP-binding RAS-like 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8500	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8500	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	drn-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	diras2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	diras2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	12,882,224 - 12,913,366 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	12,880,385 - 12,914,291 (+)	Ensembl				GRCr8
mRatBN7.2	17	12,730,040 - 12,761,511 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	12,725,149 - 12,761,663 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	12,691,363 - 12,692,565 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	14,296,434 - 14,297,634 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	12,613,401 - 12,614,601 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	12,738,078 - 12,766,700 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	12,762,752 - 12,763,952 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	14,826,986 - 14,858,039 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	18,604,023 - 18,605,223 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	12,518,650 - 12,519,850 (+)	NCBI		Celera
RGSC_v3.1	17	18,604,054 - 18,604,654 (+)	NCBI
Cytogenetic Map	17	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,4'-trichlorobiphenyl (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

dimethylarsinic acid (ISO)

dorsomorphin (ISO)

ethanol (ISO)

fonofos (ISO)

fructose (ISO)

fulvestrant (ISO)

glucose (ISO)

glyphosate (ISO)

lipopolysaccharide (ISO)

methylarsonic acid (ISO)

mono(2-ethylhexyl) phthalate (ISO)

ozone (ISO)

parathion (ISO)

PCB138 (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

terbufos (ISO)

tetraphene (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of MAP kinase activity (ISO)

signal transduction (IEA)

small GTPase-mediated signal transduction (IBA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

Molecular Function

GTP binding (IEA,ISO)

GTPase activity (IBA,IEA,ISO)

nucleotide binding (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12194967	PMID:25931508	PMID:26149690	PMID:33450132

Genomics

Comparative Map Data

Diras2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	12,882,224 - 12,913,366 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	12,880,385 - 12,914,291 (+)	Ensembl				GRCr8
mRatBN7.2	17	12,730,040 - 12,761,511 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	12,725,149 - 12,761,663 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	12,691,363 - 12,692,565 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	14,296,434 - 14,297,634 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	12,613,401 - 12,614,601 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	12,738,078 - 12,766,700 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	12,762,752 - 12,763,952 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	14,826,986 - 14,858,039 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	18,604,023 - 18,605,223 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	12,518,650 - 12,519,850 (+)	NCBI		Celera
RGSC_v3.1	17	18,604,054 - 18,604,654 (+)	NCBI
Cytogenetic Map	17	p14	NCBI

DIRAS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	90,609,832 - 90,642,824 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	90,609,832 - 90,642,862 (-)	Ensembl			hg38	GRCh38
GRCh37	9	93,372,114 - 93,405,106 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	92,411,934 - 92,444,928 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	90,451,667 - 90,484,662	NCBI
Celera	9	63,806,753 - 63,839,749 (-)	NCBI		Celera
Cytogenetic Map	9	q22.2	NCBI
HuRef	9	63,052,764 - 63,085,766 (-)	NCBI		HuRef
CHM1_1	9	93,518,607 - 93,551,600 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	102,774,878 - 102,807,866 (-)	NCBI		T2T-CHM13v2.0

Diras2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	52,658,411 - 52,685,390 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	52,658,416 - 52,685,315 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	52,504,375 - 52,531,354 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	52,504,380 - 52,531,279 (-)	Ensembl			mm10	GRCm38
MGSCv37	13	52,599,744 - 52,626,205 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	52,516,812 - 52,543,086 (-)	NCBI		MGSCv36	mm8
Celera	13	53,580,860 - 53,607,323 (-)	NCBI		Celera
Cytogenetic Map	13	A5	NCBI
cM Map	13	27.3	NCBI

Diras2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955515	1,526,333 - 1,551,811 (+)	Ensembl
ChiLan1.0	NW_004955515	1,526,436 - 1,551,811 (+)	NCBI	ChiLan1.0	ChiLan1.0

DIRAS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	48,823,151 - 48,856,390 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	48,825,551 - 48,858,780 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	61,694,582 - 61,727,808 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	89,794,504 - 89,827,725 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	89,797,897 - 89,798,496 (-)	Ensembl			panPan2	panpan1.1

DIRAS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	96,057,595 - 96,082,063 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	96,510,091 - 96,535,201 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	96,660,495 - 96,685,610 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	96,660,789 - 96,685,608 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	96,287,919 - 96,312,999 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	96,008,459 - 96,033,556 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	96,768,562 - 96,793,678 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Diras2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	12,232,904 - 12,264,012 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936780	1,380,876 - 1,381,475 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936780	1,377,569 - 1,408,889 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DIRAS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	1,964,849 - 1,987,891 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	1,964,842 - 1,987,900 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	2,406,324 - 2,406,923 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DIRAS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	101,071,595 - 101,102,883 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	101,074,992 - 101,075,591 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	89,405,540 - 89,437,227 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Diras2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624868	1,832,727 - 1,863,089 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624868	1,832,696 - 1,862,947 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Diras2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	14	70,826,004 - 70,854,890 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Diras2
398 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	69
Count of miRNA genes:	64
Interacting mature miRNAs:	67
Transcripts:	ENSRNOT00000044842
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	43999106	Rat
2300002	Iddm36	Insulin dependent diabetes mellitus QTL 36	1.98		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	9266755	40968173	Rat
2293664	Bmd28	Bone mineral density QTL 28	5.1	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	17	4360057	27233623	Rat
8552966	Pigfal18	Plasma insulin-like growth factor 1 level QTL 18	8.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	12860942	57860942	Rat
1300123	Bp194	Blood pressure QTL 194	2.82		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	2120843	42054133	Rat
1582224	Epfw4	Epididymal fat weight QTL 4	3.5	0.0058	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	17	9206505	23859062	Rat
1582225	Bw67	Body weight QTL 67	6.2	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
2302377	Scl61	Serum cholesterol level QTL 61	4.36		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	17	6221998	58177198	Rat
1582226	Bw64	Body weight QTL 64	4.2	0.0017	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9589151	Insul30	Insulin level QTL 30	8.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	12860942	57860942	Rat
10401807	Kidm52	Kidney mass QTL 52			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	1	31706603	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	4733534	49733534	Rat
9589057	Scfw6	Subcutaneous fat weight QTL 6	8.62	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	17	12860942	57860942	Rat
1582208	Kidm32	Kidney mass QTL 32	3.9	0.0018	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	9206505	23859062	Rat
9590154	Scort9	Serum corticosterone level QTL 9	23.57	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	12860942	57860942	Rat
9590088	Insglur7	Insulin/glucose ratio QTL 7	20.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	17	12860942	57860942	Rat
1549900	Iddm20	Insulin dependent diabetes mellitus QTL 20	3.7		pancreas integrity trait (VT:0010560)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	17	1	22181410	Rat
2317053	Aia25	Adjuvant induced arthritis QTL 25	2.69		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	10604694	55604694	Rat
1354613	Kidm14	Kidney mass QTL 14	6.2		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	17	1	36045694	Rat
7411666	Foco31	Food consumption QTL 31	11.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	17	12860942	57860942	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)	17	1	21499218	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	4733534	49733534	Rat
1581553	Pur14	Proteinuria QTL 14	5.3	0.0001	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	17	7985243	16523460	Rat
70184	BpQTLcluster14	Blood pressure QTL cluster 14	3.38		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	8574342	32199534	Rat
1582258	Bw76	Body weight QTL 76	4.6	0.0005	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
631207	Niddm41	Non-insulin dependent diabetes mellitus QTL 41			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	1	38037084	Rat
1582199	Insul5	Insulin level QTL 5	3.4	0.0119	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	17	9206505	23859062	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	43999106	Rat
2293648	Bmd31	Bone mineral density QTL 31	4.5	0.0001	femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	17	4360057	27233623	Rat
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	43999106	Rat
1641902	Colcr7	Colorectal carcinoma resistance QTL 7	3.35	0.0044	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	17	2120843	22087569	Rat
1582241	Bw70	Body weight QTL 70	4.6	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
1582245	Bw73	Body weight QTL 73	4.6	0.0004	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9590316	Scort21	Serum corticosterone level QTL 21	4.75	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	1	22877318	Rat

Markers in Region

D17Rat157

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	17	12,907,953 - 12,908,162 (+)	Marker Load Pipeline
mRatBN7.2	17	12,756,092 - 12,756,301 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	12,761,280 - 12,761,488	NCBI	Rnor6.0
Rnor_5.0	17	14,852,619 - 14,852,827	UniSTS	Rnor5.0
RGSC_v3.4	17	18,602,550 - 18,602,759	RGD	RGSC3.4
RGSC_v3.4	17	18,602,551 - 18,602,759	UniSTS	RGSC3.4
Celera	17	12,517,178 - 12,517,386	UniSTS
RGSC_v3.1	17	18,602,550 - 18,602,759	RGD
RH 2.0 Map	17	91.2	RGD
SHRSP x BN Map	17	10.5599	RGD
Cytogenetic Map	17	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	9	66	155	74	71	42	86	42	6	299	183	11	134	52	91	29	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001169578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039095475	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000044842 ⟹ ENSRNOP00000041046

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	17	12,762,752 - 12,763,952 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098786 ⟹ ENSRNOP00000091025

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,881,859 - 12,914,291 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,726,911 - 12,761,663 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105100 ⟹ ENSRNOP00000090855

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,881,493 - 12,913,372 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,729,947 - 12,761,663 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107110 ⟹ ENSRNOP00000093582

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,880,499 - 12,913,372 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,727,946 - 12,761,663 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118934 ⟹ ENSRNOP00000078392

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,880,385 - 12,913,645 (+)	Ensembl
mRatBN7.2 Ensembl	17	12,725,149 - 12,761,663 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000149958 ⟹ ENSRNOP00000108684

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	12,881,859 - 12,914,291 (+)	Ensembl

RefSeq Acc Id:

NM_001169578 ⟹ NP_001163049

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,909,426 - 12,910,626 (+)	NCBI
mRatBN7.2	17	12,757,565 - 12,758,765 (+)	NCBI
Rnor_6.0	17	12,762,752 - 12,763,952 (+)	NCBI
Rnor_5.0	17	14,826,986 - 14,858,039 (+)	NCBI
RGSC_v3.4	17	18,604,023 - 18,605,223 (+)	RGD
Celera	17	12,518,650 - 12,519,850 (+)	RGD

Sequence:

show sequence

CTCCTGGTCAGTAGCTGGAATTCTGAAGCAACATGCCGGAACAGAGCAATGACTACCGGGTGGC
CGTGTTTGGGGCAGGTGGCGTTGGCAAGAGCTCCCTGGTTTTGAGGTTTGTGAAAGGGACCTTC
AGGGAGAGCTACATCCCAACTGTGGAAGACACCTACCGGCAGGTGATCAGCTGTGACAAGAGCA
TCTGTACGCTGCAGATCACCGACACGACCGGGAGCCACCAGTTCCCGGCCATGCAGCGGCTGTC
CATCTCCAAGGGCCACGCCTTCATCCTGGTCTACTCCATTACCAGCCGGCAGTCCCTGGAGGAA
CTCAAGCCCATCTATGAGCAGATCTGCGAGATCAAGGGGGATGTGGAGAGCATCCCCATCATGC
TGGTGGGGAACAAGTGTGACGAGAGCCCCAACCGCGAGGTCCAGAGCAGCGAGGCGGAGGCCCT
GGCGCGCACGTGGAAGTGTGCCTTCATGGAGACATCGGCCAAGCTCAACCACAACGTCAAGGAA
CTCTTTCAGGAGCTACTGAACCTGGAGAAGCGCAGGACCGTGAGCCTCCAGATCGATGGCAAGA
AGAGCAAGCAGCAGAAGAGGAAGGAGAAGCTCAAGGGCAAGTGTGTGGTCATGTGAGAGGCCTT
TGTGCAGAAAGAGCTGCTGCTGCCCTCAGGGCCTCTCTCTTCCTCCCCTCTGTGAACCCCACTG
TCGTCAGGGCAGCATGTCCGATGCCCGTGTGTTAAACATTGCATTTGGCTGCGACACACCCTGC
AAATGTCCTTAAGAGGCATTCCACACGCCCCACTAGCCCACCCCTCAGGAGACGCAGAATCTGG
GAAGCTCTTAGCATCCCCGGGAGCGGAGGCCAGTCCTGAATGGGCTTTAGCCATTGGAAGATGA
GGGGACTCAGAGCTGTGGACCCGGGAGAAACTGAGGGTACTGTGTAATGCATGTGCGTGTGACA
TAGCTACTGGTACCACCCCACATCAGGCAACCTAGTTTGGAAGCCACTAACATCTTTGGGGGGG
GGGAGGAGCAGGCAGTCGAAGGAAGTGAGAAACCCGTGGACCCCAGCGGTTCCCATGAGTGGAT
TTTTAGTGGGATTAAAGATTAAATACCACAGTCCCCATCTAAGCGATGCTCATGCCATTCCTAC
TGACACACACTGAGGGGGTTGGCCCCCTCATTCCTCAAAGCCTTCTTAG

hide sequence

RefSeq Acc Id:

XM_006253671 ⟹ XP_006253733

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,882,224 - 12,913,366 (+)	NCBI
mRatBN7.2	17	12,730,040 - 12,761,511 (+)	NCBI
Rnor_6.0	17	12,738,078 - 12,766,700 (+)	NCBI
Rnor_5.0	17	14,826,986 - 14,858,039 (+)	NCBI

Sequence:

show sequence

GCGCGCTCCGCCTCGCGGAGCTGCGCCTGGAGACCTGCCGCTCTGAGCCGGCTCTCCCCAGGTA
CCTCCTGGTCAGTAGCTGGAATTCTGAAGCAACATGCCGGAACAGAGCAATGACTACCGGGTGG
CCGTGTTTGGGGCAGGTGGCGTTGGCAAGAGCTCCCTGGTTTTGAGGTTTGTGAAAGGGACCTT
CAGGGAGAGCTACATCCCAACTGTGGAAGACACCTACCGGCAGGTGATCAGCTGTGACAAGAGC
ATCTGTACGCTGCAGATCACCGACACGACCGGGAGCCACCAGTTCCCGGCCATGCAGCGGCTGT
CCATCTCCAAGGGCCACGCCTTCATCCTGGTCTACTCCATTACCAGCCGGCAGTCCCTGGAGGA
ACTCAAGCCCATCTATGAGCAGATCTGCGAGATCAAGGGGGATGTGGAGAGCATCCCCATCATG
CTGGTGGGGAACAAGTGTGACGAGAGCCCCAACCGCGAGGTCCAGAGCAGCGAGGCGGAGGCCC
TGGCGCGCACGTGGAAGTGTGCCTTCATGGAGACATCGGCCAAGCTCAACCACAACGTCAAGGA
ACTCTTTCAGGAGCTACTGAACCTGGAGAAGCGCAGGACCGTGAGCCTCCAGATCGATGGCAAG
AAGAGCAAGCAGCAGAAGAGGAAGGAGAAGCTCAAGGGCAAGTGTGTGGTCATGTGAGAGGCCT
TTGTGCAGAAAGAGCTGCTGCTGCCCTCAGGGCCTCTCTCTTCCTCCCCTCTGTGAACCCCACT
GTCGTCAGGGCAGCATGTCCGATGCCCGTGTGTTAAACATTGCATTTGGCTGCGACACACCCTG
CAAATGTCCTTAAGAGGCATTCCACACGCCCCACTAGCCCACCCCTCAGGAGACGCAGAATCTG
GGAAGCTCTTAGCATCCCCGGGAGCGGAGGCCAGTCCTGAATGGGCTTTAGCCATTGGAAGATG
AGGGGACTCAGAGCTGTGGACCCGGGAGAAACTGAGGGTACTGTGTAATGCATGTGCGTGTGAC
ATAGCTACTGGTACCACCCCACATCAGGCAACCTAGTTTGGAAGCCACTAACATCTTTGGGGGG
GGGGAGGAGCAGGCAGTCGAAGGAAGTGAGAAACCCGTGGACCCCAGCGGTTCCCATGAGTGGA
TTTTTAGTGGGATTAAAGATTAAATACCACAGTCCCCATCTAAGCGATGCTCATGCCATTCCTA
CTGACACACACTGAGGGGGTTGGCCCCCTCATTCCTCAAAGCCTTCTTAGCAAGTACCGTGTCA
GCCTGTTAGGAGTATACACTTCACCTGTAATGCCAAGGCCACTTGTGGCACGATGCTGTGTCAG
CACTTCTTCGGTTTCTGAGTCGGGACATTGTGACATCATGTAAACATCGCAATAACGCCCGTGT
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCCGCGCACGCGCGTGTGCGTGTGCTATA
CTTTGAGGGTTCTAGAAATGTGAACTTTCCTCCTTTTGACCTTCGAGGGTTGCCACTTCTTCCA
GCCCTCTGATTTTTAAATAAAAGGAAATAAAAGTAGGCATTTTTTTAGACTCCCTCTTCCCCTC
CCCCCAAGATGGTTTTCTTGTCTTAAATAACTCCATGTGTACCCAGCTGGGAACCAGCCAACCA
AGAGCGTCTAACAACCAGAAGCACATCCATTTTTCTAGACGACACAAGCATGTAGATGCTGTGC
ACCGCGACTTAACGAAATACTTTGAAACGGACGCTATTCACTGTGTTTTTAACGATTTATCTAC
ACCGGAAGTAGATTGCTAGGGAGTACGTCTACTTCCCGGTAAACCTTCTCCTCTCAATTTCAAC
CTTGCTAAACGTCCTGAAGAGTTCCTCAGTTCCGCATGCACCCCAGAAGAAATCCTCTCCTCAG
GACATTGAATGCACCCCATATTCCTTAGAACGAGCCCCAGCCGCTGCTTGAGGGATCAGCGGCC
AGCAGCAGATAGGTTGGTCTAGTCTCTCTTTTCTGGGCCCAGTGCCCATGCTTTAATGTAATTT
GCCTCCCATCTTGGAGTCCAGCTGGATTCTGATTATTGGAAATTCTTATGTACACAGCCAATGA
GAAGGTGTTTCACACGGTAGGATAAACCCATGCTGGTCTTTGGTGCCAGTTCGATCACTCTCTT
AGCCATCTTACCACTGACCAGCCAGCAGGTAGAGGAGGTTGTAGCACTGACTGTGTGAGCCTAA
ACAGTACTCTCATGGCCAGTGGGCAGAGGTCCCAATGCCGGGGTGTTCTGGTAGGCCTCTTGCT
CCACCATTGCCTCTGAAGCACACTGTGTTCAAACACCCTCTCTTCCTTCAGACCTCTATGATTC
AGTCCTCTTGTCTGGTCTGGCCCTCTCTGCTCTTTCAACCACAACCCACCCTGGTGATATGCTG
AGGGTCAGGGAGGTCCCTCAGAAAACCATATGCCTCAACGATCTTCCCATCTCCTTAGACTTCT
AGAACAAAACCCTTGGGGTTACCTGGGCAAGCAGCCACCCTGAGAAATGAGCAAGTCTGGGAAC
CAAGCAAGAGCCTGGAGCGCTTGTGTCCCCTTCCAGACCCACTCTGAACCTCTCCCGTCATCCC
TGTTTGTCCCCAGTGGCCATTCCCTCACAGTAACATGGAGTTGTGGAATTTTCTAGAATGTCTT
TAATTTGTTGCTCTATTTCTCCTCTCAGAGAAAACATATCAGCTTGCCATTTTGGATTTGGGAA
CAGCGAGGGAAAGACCACGGCTCTGTGGATGATGTGACATTATATACATTATATATACACATCC
TAGAGGATATATATGTTTGTGGGTGGTCCCTTCGCAGTAAAATCCTGTCTGTCCTACCGACTGT
AACCACGCTTTTGACATGAGTGTTGCTACATGCTTCCCCGTCCCCAGTGACCACACATCAAGTT
TCTTTCAGCCCCGTCAGTCAGTTTCCGGATCCCGAAGGCTTTCAGTCTTCATTGGCAGGAGGAT
CTTGCTACAGTTCCATTAAGAGTCTTTGCTCCTCTCTGTGCTGCCTGTTTGTTTAGAGGATGGG
AGGGAGGTCAGTGAAGCCTCCCTTCTCAGGCTTCATTGGGACACTGTGTTCTGTAGATCGAGCT
GAGCACTGGGTAGCTATCTTAATGTCACCTTTGGGCAAGCTTCCCTCTGACTCAGGGGCCGAGG
ACAGCGGCTTTCAGCTCTGCTTCGGTCCCATCCCAAGTCAGGAAGCTGGGCCTCTTGGTAACAT
CCCACACTGCACACGGGGCTGGAAATTCCTGACCCAGCCCCGGCTCGTTATAAAACTTGAAATA
TTGCTTTGAAGATGGCACTCTGGGGTTAAGCACGGGGCTCCATGAGTTCCCTAATCCCCAACGG
TCCCCTCTCCATTCAGTGACAAGCCATGGGCACGCATCCAATGCATTAAGTCCATACAAGAGCA
ATATATCCAAGTGTCCACTAGATCCAAACCAATATATATATATAATGTAATTTATCTTCCTGCA
CTTTCGAGGTATAAAGTAGTAAATTGTATATACCTAATCTCTATATATCCACATGCTAGTATAT
CGGTCTCACTATTTGTAACATCCTTTGTAGAACAAAATGTACTAAATATTTTAGAATTGCGCTG
TGATATCCCTCCCCACCCCCACCCCCCCAAGTTTGTAAAGCTCTGCTCCTACACGAGCTGTCTG
GAAATACCCAAAGCCAAAGGGGCATGTGGAACTCCTACAGGAAGGACACCTCCTGGGATTCAGT
AGCCCACAAAGACCTTGTGTCAAACCAACTATCTGCAGAGCGAGCATCGGCATGCGAGATGCCG
GCACATGCTCCCACTTCCGCCGGCCCTTGCTGTTCCGGTTCCATTTTTTTTTTTTTTTGGGTAT
GTCTGACATAACTCTATGGTTATGAGAATCACCTTGTATAAGGTTCTAGCGGCAGCCATGGCCC
CAATCCGTGGAACCAGTTACAATAAAGCTCAGTTACGGCACCCTGA

hide sequence

RefSeq Acc Id:

XM_039095475 ⟹ XP_038951403

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	12,891,489 - 12,913,366 (+)	NCBI
mRatBN7.2	17	12,739,607 - 12,761,511 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001163049	(Get FASTA)	NCBI Sequence Viewer
	XP_006253733	(Get FASTA)	NCBI Sequence Viewer
	XP_038951403	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000078392.1
	ENSRNOP00000090855.1
	ENSRNOP00000091025
	ENSRNOP00000091025.1
	ENSRNOP00000093582.1
	ENSRNOP00000108684
	ENSRNOP00000108684.1

RefSeq Acc Id:

NP_001163049 ⟸ NM_001169578

- UniProtKB:

A0A8I5ZKR8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTG
SHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPN
REVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKL
KGKCVVM

hide sequence

RefSeq Acc Id:

XP_006253733 ⟸ XM_006253671

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTG
SHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPN
REVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKL
KGKCVVM

hide sequence

Ensembl Acc Id:

ENSRNOP00000041046 ⟸ ENSRNOT00000044842

RefSeq Acc Id:	XP_038951403 ⟸ XM_039095475
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZKR8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000091025 ⟸ ENSRNOT00000098786

Ensembl Acc Id:

ENSRNOP00000093582 ⟸ ENSRNOT00000107110

Ensembl Acc Id:

ENSRNOP00000078392 ⟸ ENSRNOT00000118934

Ensembl Acc Id:

ENSRNOP00000090855 ⟸ ENSRNOT00000105100

Ensembl Acc Id:

ENSRNOP00000108684 ⟸ ENSRNOT00000149958

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZHX3-F1-model_v2	AlphaFold	D3ZHX3	1-199	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305580	AgrOrtholog
BioCyc Gene	G2FUF-10095	BioCyc
Ensembl Genes	ENSRNOG00000032328	Ensembl
	ENSRNOG00000062731	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000098786	ENTREZGENE
	ENSRNOT00000098786.2	UniProtKB/TrEMBL
	ENSRNOT00000105100.2	UniProtKB/TrEMBL
	ENSRNOT00000107110.2	UniProtKB/TrEMBL
	ENSRNOT00000118934.2	UniProtKB/TrEMBL
	ENSRNOT00000149958	ENTREZGENE
	ENSRNOT00000149958.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
	Small_GTPase_Ras-type	UniProtKB/TrEMBL
KEGG Report	rno:291006	UniProtKB/TrEMBL
NCBI Gene	291006	ENTREZGENE
PANTHER	PTHR24070	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PhenoGen	Diras2	PhenoGen
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000032328	RatGTEx
	ENSRNOG00000062731	RatGTEx
SMART	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8I5ZKR8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-11	Diras2	DIRAS family GTPase 2	Diras2	DIRAS family, GTP-binding RAS-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Diras2	DIRAS family, GTP-binding RAS-like 2	Diras2_predicted	DIRAS family, GTP-binding RAS-like 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Diras2_predicted	DIRAS family, GTP-binding RAS-like 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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