Gene: Diras2 (DIRAS family GTPase 2) Rattus norvegicus
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Symbol:
Diras2
Name:
DIRAS family GTPase 2
RGD ID:
1305580
Description:
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in small GTPase-mediated signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human DIRAS2 (DIRAS family GTPase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
DIRAS family, GTP-binding RAS-like 2; GTP-binding protein Di-Ras2; LOC291006
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
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Orthologs 1
Homo sapiens (human):
DIRAS2 (DIRAS family GTPase 2)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Diras2 (DIRAS family, GTP-binding RAS-like 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Diras2 (DIRAS family GTPase 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
DIRAS2 (DIRAS family GTPase 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
DIRAS2 (DIRAS family GTPase 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Diras2 (DIRAS family GTPase 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
DIRAS2 (DIRAS family GTPase 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
DIRAS2 (DIRAS family GTPase 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Diras2 (DIRAS family GTPase 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Diras2 (DIRAS family GTPase 2)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
DIRAS2 (DIRAS family GTPase 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Diras2 (DIRAS family, GTP-binding RAS-like 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG8500
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG8500
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Caenorhabditis elegans (roundworm):
drn-1
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
diras2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
diras2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 17 12,882,224 - 12,913,366 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 17 12,880,385 - 12,914,291 (+) Ensembl GRCr8 mRatBN7.2 17 12,730,040 - 12,761,511 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 17 12,725,149 - 12,761,663 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 17 12,691,363 - 12,692,565 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 17 14,296,434 - 14,297,634 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 17 12,613,401 - 12,614,601 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 17 12,868,575 - 12,869,775 (+) NCBI Dahl_SR_JrHsd Lyon_Normotensive 17 12,850,738 - 12,851,938 (+) NCBI Lyon_Normotensive Lyon_Hypertensive 17 12,861,889 - 12,863,089 (+) NCBI Lyon_Hypertensive F344_StmMcwi 17 12,936,373 - 12,937,573 (+) NCBI F344_StmMcwi Rnor_6.0 17 12,738,078 - 12,766,700 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 17 12,762,752 - 12,763,952 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 17 14,826,986 - 14,858,039 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 17 18,604,023 - 18,605,223 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 17 12,518,650 - 12,519,850 (+) NCBI Celera RGSC_v3.1 17 18,604,054 - 18,604,654 (+) NCBI Cytogenetic Map 17 p14 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Diras2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Diras2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Diras2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Diras2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Diras2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Diras2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Diras2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of DIRAS2 mRNA CTD PMID:32109520 Diras2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of DIRAS2 mRNA CTD PMID:33387578 Diras2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Diras2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Diras2 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO DIRAS2 (Homo sapiens) 6480464 2,2',4,4',5-brominated diphenyl ether results in increased expression of DIRAS2 mRNA CTD PMID:26705709 Diras2 Rat aflatoxin B1 decreases methylation ISO DIRAS2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of DIRAS2 intron CTD PMID:30157460 Diras2 Rat aldehydo-D-glucose multiple interactions ISO Diras2 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... CTD PMID:37567420 Diras2 Rat all-trans-retinoic acid multiple interactions ISO Diras2 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DIRAS2 mRNA CTD PMID:36189433 Diras2 Rat all-trans-retinoic acid increases expression ISO Diras2 (Mus musculus) 6480464 Tretinoin results in increased expression of DIRAS2 mRNA CTD PMID:36189433 Diras2 Rat arsane increases expression ISO DIRAS2 (Homo sapiens) 6480464 Arsenic results in increased expression of DIRAS2 mRNA CTD PMID:36861143 Diras2 Rat arsenic atom increases expression ISO DIRAS2 (Homo sapiens) 6480464 Arsenic results in increased expression of DIRAS2 mRNA CTD PMID:36861143 Diras2 Rat atrazine increases expression ISO DIRAS2 (Homo sapiens) 6480464 Atrazine results in increased expression of DIRAS2 mRNA CTD PMID:22378314 Diras2 Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of DIRAS2 gene CTD PMID:35440735 Diras2 Rat benzo[a]pyrene multiple interactions ISO Diras2 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to DIRAS2 promoter] CTD PMID:19654925 Diras2 Rat benzo[a]pyrene affects methylation ISO DIRAS2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of DIRAS2 5' UTR CTD PMID:27901495 Diras2 Rat benzo[a]pyrene increases methylation ISO DIRAS2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of DIRAS2 promoter CTD PMID:27901495 Diras2 Rat benzo[a]pyrene increases expression ISO DIRAS2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of DIRAS2 mRNA CTD PMID:22316170 Diras2 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Diras2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of DIRAS2 mRNA CTD PMID:34319233 Diras2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of DIRAS2 mRNA CTD PMID:25181051|PMID:30816183|PMID:34947998 Diras2 Rat bisphenol A multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of DIRAS2 gene CTD PMID:31601247 Diras2 Rat bisphenol F decreases expression ISO Diras2 (Mus musculus) 6480464 bisphenol F results in decreased expression of DIRAS2 mRNA CTD PMID:30951980 Diras2 Rat cadmium atom multiple interactions ISO Diras2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DIRAS2 more ... CTD PMID:37325564 Diras2 Rat cadmium dichloride multiple interactions ISO Diras2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DIRAS2 more ... CTD PMID:37325564 Diras2 Rat carbon nanotube decreases expression ISO Diras2 (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of DIRAS2 mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681 Diras2 Rat CGP 52608 multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to DIRAS2 gene] CTD PMID:28238834 Diras2 Rat chlorpyrifos decreases expression ISO Diras2 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of DIRAS2 mRNA CTD PMID:37019170 Diras2 Rat cyclosporin A increases expression ISO DIRAS2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of DIRAS2 mRNA CTD PMID:20106945 Diras2 Rat D-glucose multiple interactions ISO Diras2 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... CTD PMID:37567420 Diras2 Rat dexamethasone increases expression ISO Diras2 (Mus musculus) 6480464 Dexamethasone results in increased expression of DIRAS2 mRNA CTD PMID:22733784 Diras2 Rat dibutyl phthalate increases expression ISO Diras2 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of DIRAS2 mRNA CTD PMID:21266533 Diras2 Rat dimethylarsinic acid multiple interactions ISO Diras2 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... CTD PMID:34876320 Diras2 Rat dorsomorphin multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Diras2 Rat ethanol affects splicing ISO Diras2 (Mus musculus) 6480464 Ethanol affects the splicing of DIRAS2 mRNA CTD PMID:30319688 Diras2 Rat ethanol affects expression ISO Diras2 (Mus musculus) 6480464 Ethanol affects the expression of DIRAS2 mRNA CTD PMID:30319688 Diras2 Rat fonofos increases methylation ISO DIRAS2 (Homo sapiens) 6480464 Fonofos results in increased methylation of DIRAS2 promoter CTD PMID:22847954 Diras2 Rat fructose multiple interactions ISO Diras2 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... CTD PMID:37567420 Diras2 Rat fulvestrant multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of DIRAS2 gene CTD PMID:31601247 Diras2 Rat glucose multiple interactions ISO Diras2 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... CTD PMID:37567420 Diras2 Rat glyphosate multiple interactions ISO Diras2 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... CTD PMID:37567420 Diras2 Rat lipopolysaccharide multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of DIRAS2 mRNA CTD PMID:35811015 Diras2 Rat methylarsonic acid multiple interactions ISO Diras2 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... CTD PMID:34876320 Diras2 Rat mono(2-ethylhexyl) phthalate increases expression ISO Diras2 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of DIRAS2 mRNA CTD PMID:36189433 Diras2 Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Diras2 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DIRAS2 mRNA CTD PMID:36189433 Diras2 Rat ozone multiple interactions ISO Diras2 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... CTD PMID:34911549 Diras2 Rat parathion increases methylation ISO DIRAS2 (Homo sapiens) 6480464 Parathion results in increased methylation of DIRAS2 promoter CTD PMID:22847954 Diras2 Rat PCB138 multiple interactions ISO Diras2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Diras2 Rat phenylmercury acetate multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Diras2 Rat pirinixic acid multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Diras2 Rat resveratrol multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of DIRAS2 mRNA CTD PMID:23557933 Diras2 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of DIRAS2 mRNA CTD PMID:35811015 Diras2 Rat SB 431542 multiple interactions ISO DIRAS2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Diras2 Rat sodium arsenate multiple interactions ISO Diras2 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... CTD PMID:34876320 Diras2 Rat sodium arsenite increases expression ISO Diras2 (Mus musculus) 6480464 sodium arsenite results in increased expression of DIRAS2 mRNA CTD PMID:37682722 Diras2 Rat sodium arsenite multiple interactions ISO Diras2 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... CTD PMID:34876320 Diras2 Rat terbufos increases methylation ISO DIRAS2 (Homo sapiens) 6480464 terbufos results in increased methylation of DIRAS2 promoter CTD PMID:22847954 Diras2 Rat tetraphene decreases expression ISO Diras2 (Mus musculus) 6480464 benz(a)anthracene results in decreased expression of DIRAS2 mRNA CTD PMID:26377693 Diras2 Rat titanium dioxide decreases methylation ISO Diras2 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of DIRAS2 gene CTD PMID:35295148 Diras2 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of DIRAS2 mRNA CTD PMID:33387578 Diras2 Rat valproic acid decreases methylation ISO DIRAS2 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of DIRAS2 gene CTD PMID:29154799 Diras2 Rat valproic acid increases expression ISO DIRAS2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of DIRAS2 mRNA CTD PMID:24383497|PMID:26272509|PMID:28001369